IPET-CT in inflammatory diseases of kidneys and bladder: diagnostic efficacy
Introduction. The incorporation of combined positron emission tomography-computed tomography (PET-CT) into clinical practice has significantly expanded the understanding of the pathogenesis of many diseases. Evidence-based data on the diagnostic efficacy in infectious and inflammatory diseases is in...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
V. B. Berdichevsky [verfasserIn] B. A. Berdichevsky [verfasserIn] A. V. Romanova [verfasserIn] F. R. Rasulov [verfasserIn] A. A. Naletov [verfasserIn] S. V. Khilkevich [verfasserIn] E. I. Gutrova [verfasserIn] A. L. Boldyrev [verfasserIn] M. A. Korabelnikov [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Russisch |
| Erschienen: |
2021 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
In: Vestnik Urologii - State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation, 2018, 9(2021), 4, Seite 13-20 |
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| Übergeordnetes Werk: |
volume:9 ; year:2021 ; number:4 ; pages:13-20 |
| Links: |
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| DOI / URN: |
10.21886/2308-6424-2021-9-4-13-20 |
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| Katalog-ID: |
DOAJ030716918 |
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| 520 | |a Introduction. The incorporation of combined positron emission tomography-computed tomography (PET-CT) into clinical practice has significantly expanded the understanding of the pathogenesis of many diseases. Evidence-based data on the diagnostic efficacy in infectious and inflammatory diseases is increasing, making this imaging method very promising. Purpose of the study. To study the diagnostic efficacy of 18F-FDG PET-CT in various chronic inflammatory diseases of kidneys and bladder.Materials and methods. A retrospective study of the results of whole-body 18F-FDG PET-CT in 45 patients was carried out. Patients underwent an investigation at various times after surgical treatment of localized oncology of the anogenital zone at the T1N0M0 stage without the involvement of the genitourinary system. It was found that 24 patients had a history of chronic pyelonephritis and 21 patients had manifestations of radiation cystitis. Repeated PET/CT scans were performed after a course of therapy for inflammatory urological diseases to assess the treatment results of the underlying pathology.Results. The latent course of chronic renal failure was accompanied by a diffuse decrease in 18F-FDG metabolism in the renal parenchyma with its partial recovery after etiotropic therapy and urine sanitation. Hypermetabolism of 18F-FDG was detected in the bladder wall during manifestations of radiation cystitis, which was leveled during therapy and relief of urinary syndrome manifestations. Bacterial and radiation inflammation differed in molecular-cell responses to the pathogen, while the results of urinalysis, indicating the effectiveness of the treatment, coincided with the visual and digital indicators of the restoration of adequate energy metabolism in the studied tissues.Conclusions. Metabolism of 18F-FDG in the kidneys and bladder can objectively reflect the nature of inflammation and complement the data on the effectiveness of the treatment. | ||
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| 650 | 4 | |a 18f-fdg metabolism | |
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| 700 | 0 | |a A. V. Romanova |e verfasserin |4 aut | |
| 700 | 0 | |a F. R. Rasulov |e verfasserin |4 aut | |
| 700 | 0 | |a A. A. Naletov |e verfasserin |4 aut | |
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| 700 | 0 | |a A. L. Boldyrev |e verfasserin |4 aut | |
| 700 | 0 | |a M. A. Korabelnikov |e verfasserin |4 aut | |
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10.21886/2308-6424-2021-9-4-13-20 doi (DE-627)DOAJ030716918 (DE-599)DOAJc09ec8d86df14e41abcd02816c5eaa30 DE-627 ger DE-627 rakwb rus RC870-923 V. B. Berdichevsky verfasserin aut IPET-CT in inflammatory diseases of kidneys and bladder: diagnostic efficacy 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction. The incorporation of combined positron emission tomography-computed tomography (PET-CT) into clinical practice has significantly expanded the understanding of the pathogenesis of many diseases. Evidence-based data on the diagnostic efficacy in infectious and inflammatory diseases is increasing, making this imaging method very promising. Purpose of the study. To study the diagnostic efficacy of 18F-FDG PET-CT in various chronic inflammatory diseases of kidneys and bladder.Materials and methods. A retrospective study of the results of whole-body 18F-FDG PET-CT in 45 patients was carried out. Patients underwent an investigation at various times after surgical treatment of localized oncology of the anogenital zone at the T1N0M0 stage without the involvement of the genitourinary system. It was found that 24 patients had a history of chronic pyelonephritis and 21 patients had manifestations of radiation cystitis. Repeated PET/CT scans were performed after a course of therapy for inflammatory urological diseases to assess the treatment results of the underlying pathology.Results. The latent course of chronic renal failure was accompanied by a diffuse decrease in 18F-FDG metabolism in the renal parenchyma with its partial recovery after etiotropic therapy and urine sanitation. Hypermetabolism of 18F-FDG was detected in the bladder wall during manifestations of radiation cystitis, which was leveled during therapy and relief of urinary syndrome manifestations. Bacterial and radiation inflammation differed in molecular-cell responses to the pathogen, while the results of urinalysis, indicating the effectiveness of the treatment, coincided with the visual and digital indicators of the restoration of adequate energy metabolism in the studied tissues.Conclusions. Metabolism of 18F-FDG in the kidneys and bladder can objectively reflect the nature of inflammation and complement the data on the effectiveness of the treatment. pet- ct 18f-fdg metabolism inflammation kidneys bladder Diseases of the genitourinary system. Urology B. A. Berdichevsky verfasserin aut A. V. Romanova verfasserin aut F. R. Rasulov verfasserin aut A. A. Naletov verfasserin aut S. V. Khilkevich verfasserin aut E. I. Gutrova verfasserin aut A. L. Boldyrev verfasserin aut M. A. Korabelnikov verfasserin aut In Vestnik Urologii State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation, 2018 9(2021), 4, Seite 13-20 (DE-627)176064014X 23086424 nnns volume:9 year:2021 number:4 pages:13-20 https://doi.org/10.21886/2308-6424-2021-9-4-13-20 kostenfrei https://doaj.org/article/c09ec8d86df14e41abcd02816c5eaa30 kostenfrei https://www.urovest.ru/jour/article/view/495 kostenfrei https://doaj.org/toc/2308-6424 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 9 2021 4 13-20 |
| spelling |
10.21886/2308-6424-2021-9-4-13-20 doi (DE-627)DOAJ030716918 (DE-599)DOAJc09ec8d86df14e41abcd02816c5eaa30 DE-627 ger DE-627 rakwb rus RC870-923 V. B. Berdichevsky verfasserin aut IPET-CT in inflammatory diseases of kidneys and bladder: diagnostic efficacy 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction. The incorporation of combined positron emission tomography-computed tomography (PET-CT) into clinical practice has significantly expanded the understanding of the pathogenesis of many diseases. Evidence-based data on the diagnostic efficacy in infectious and inflammatory diseases is increasing, making this imaging method very promising. Purpose of the study. To study the diagnostic efficacy of 18F-FDG PET-CT in various chronic inflammatory diseases of kidneys and bladder.Materials and methods. A retrospective study of the results of whole-body 18F-FDG PET-CT in 45 patients was carried out. Patients underwent an investigation at various times after surgical treatment of localized oncology of the anogenital zone at the T1N0M0 stage without the involvement of the genitourinary system. It was found that 24 patients had a history of chronic pyelonephritis and 21 patients had manifestations of radiation cystitis. Repeated PET/CT scans were performed after a course of therapy for inflammatory urological diseases to assess the treatment results of the underlying pathology.Results. The latent course of chronic renal failure was accompanied by a diffuse decrease in 18F-FDG metabolism in the renal parenchyma with its partial recovery after etiotropic therapy and urine sanitation. Hypermetabolism of 18F-FDG was detected in the bladder wall during manifestations of radiation cystitis, which was leveled during therapy and relief of urinary syndrome manifestations. Bacterial and radiation inflammation differed in molecular-cell responses to the pathogen, while the results of urinalysis, indicating the effectiveness of the treatment, coincided with the visual and digital indicators of the restoration of adequate energy metabolism in the studied tissues.Conclusions. Metabolism of 18F-FDG in the kidneys and bladder can objectively reflect the nature of inflammation and complement the data on the effectiveness of the treatment. pet- ct 18f-fdg metabolism inflammation kidneys bladder Diseases of the genitourinary system. Urology B. A. Berdichevsky verfasserin aut A. V. Romanova verfasserin aut F. R. Rasulov verfasserin aut A. A. Naletov verfasserin aut S. V. Khilkevich verfasserin aut E. I. Gutrova verfasserin aut A. L. Boldyrev verfasserin aut M. A. Korabelnikov verfasserin aut In Vestnik Urologii State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation, 2018 9(2021), 4, Seite 13-20 (DE-627)176064014X 23086424 nnns volume:9 year:2021 number:4 pages:13-20 https://doi.org/10.21886/2308-6424-2021-9-4-13-20 kostenfrei https://doaj.org/article/c09ec8d86df14e41abcd02816c5eaa30 kostenfrei https://www.urovest.ru/jour/article/view/495 kostenfrei https://doaj.org/toc/2308-6424 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 9 2021 4 13-20 |
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10.21886/2308-6424-2021-9-4-13-20 doi (DE-627)DOAJ030716918 (DE-599)DOAJc09ec8d86df14e41abcd02816c5eaa30 DE-627 ger DE-627 rakwb rus RC870-923 V. B. Berdichevsky verfasserin aut IPET-CT in inflammatory diseases of kidneys and bladder: diagnostic efficacy 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction. The incorporation of combined positron emission tomography-computed tomography (PET-CT) into clinical practice has significantly expanded the understanding of the pathogenesis of many diseases. Evidence-based data on the diagnostic efficacy in infectious and inflammatory diseases is increasing, making this imaging method very promising. Purpose of the study. To study the diagnostic efficacy of 18F-FDG PET-CT in various chronic inflammatory diseases of kidneys and bladder.Materials and methods. A retrospective study of the results of whole-body 18F-FDG PET-CT in 45 patients was carried out. Patients underwent an investigation at various times after surgical treatment of localized oncology of the anogenital zone at the T1N0M0 stage without the involvement of the genitourinary system. It was found that 24 patients had a history of chronic pyelonephritis and 21 patients had manifestations of radiation cystitis. Repeated PET/CT scans were performed after a course of therapy for inflammatory urological diseases to assess the treatment results of the underlying pathology.Results. The latent course of chronic renal failure was accompanied by a diffuse decrease in 18F-FDG metabolism in the renal parenchyma with its partial recovery after etiotropic therapy and urine sanitation. Hypermetabolism of 18F-FDG was detected in the bladder wall during manifestations of radiation cystitis, which was leveled during therapy and relief of urinary syndrome manifestations. Bacterial and radiation inflammation differed in molecular-cell responses to the pathogen, while the results of urinalysis, indicating the effectiveness of the treatment, coincided with the visual and digital indicators of the restoration of adequate energy metabolism in the studied tissues.Conclusions. Metabolism of 18F-FDG in the kidneys and bladder can objectively reflect the nature of inflammation and complement the data on the effectiveness of the treatment. pet- ct 18f-fdg metabolism inflammation kidneys bladder Diseases of the genitourinary system. Urology B. A. Berdichevsky verfasserin aut A. V. Romanova verfasserin aut F. R. Rasulov verfasserin aut A. A. Naletov verfasserin aut S. V. Khilkevich verfasserin aut E. I. Gutrova verfasserin aut A. L. Boldyrev verfasserin aut M. A. Korabelnikov verfasserin aut In Vestnik Urologii State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation, 2018 9(2021), 4, Seite 13-20 (DE-627)176064014X 23086424 nnns volume:9 year:2021 number:4 pages:13-20 https://doi.org/10.21886/2308-6424-2021-9-4-13-20 kostenfrei https://doaj.org/article/c09ec8d86df14e41abcd02816c5eaa30 kostenfrei https://www.urovest.ru/jour/article/view/495 kostenfrei https://doaj.org/toc/2308-6424 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 9 2021 4 13-20 |
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10.21886/2308-6424-2021-9-4-13-20 doi (DE-627)DOAJ030716918 (DE-599)DOAJc09ec8d86df14e41abcd02816c5eaa30 DE-627 ger DE-627 rakwb rus RC870-923 V. B. Berdichevsky verfasserin aut IPET-CT in inflammatory diseases of kidneys and bladder: diagnostic efficacy 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction. The incorporation of combined positron emission tomography-computed tomography (PET-CT) into clinical practice has significantly expanded the understanding of the pathogenesis of many diseases. Evidence-based data on the diagnostic efficacy in infectious and inflammatory diseases is increasing, making this imaging method very promising. Purpose of the study. To study the diagnostic efficacy of 18F-FDG PET-CT in various chronic inflammatory diseases of kidneys and bladder.Materials and methods. A retrospective study of the results of whole-body 18F-FDG PET-CT in 45 patients was carried out. Patients underwent an investigation at various times after surgical treatment of localized oncology of the anogenital zone at the T1N0M0 stage without the involvement of the genitourinary system. It was found that 24 patients had a history of chronic pyelonephritis and 21 patients had manifestations of radiation cystitis. Repeated PET/CT scans were performed after a course of therapy for inflammatory urological diseases to assess the treatment results of the underlying pathology.Results. The latent course of chronic renal failure was accompanied by a diffuse decrease in 18F-FDG metabolism in the renal parenchyma with its partial recovery after etiotropic therapy and urine sanitation. Hypermetabolism of 18F-FDG was detected in the bladder wall during manifestations of radiation cystitis, which was leveled during therapy and relief of urinary syndrome manifestations. Bacterial and radiation inflammation differed in molecular-cell responses to the pathogen, while the results of urinalysis, indicating the effectiveness of the treatment, coincided with the visual and digital indicators of the restoration of adequate energy metabolism in the studied tissues.Conclusions. Metabolism of 18F-FDG in the kidneys and bladder can objectively reflect the nature of inflammation and complement the data on the effectiveness of the treatment. pet- ct 18f-fdg metabolism inflammation kidneys bladder Diseases of the genitourinary system. Urology B. A. Berdichevsky verfasserin aut A. V. Romanova verfasserin aut F. R. Rasulov verfasserin aut A. A. Naletov verfasserin aut S. V. Khilkevich verfasserin aut E. I. Gutrova verfasserin aut A. L. Boldyrev verfasserin aut M. A. Korabelnikov verfasserin aut In Vestnik Urologii State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation, 2018 9(2021), 4, Seite 13-20 (DE-627)176064014X 23086424 nnns volume:9 year:2021 number:4 pages:13-20 https://doi.org/10.21886/2308-6424-2021-9-4-13-20 kostenfrei https://doaj.org/article/c09ec8d86df14e41abcd02816c5eaa30 kostenfrei https://www.urovest.ru/jour/article/view/495 kostenfrei https://doaj.org/toc/2308-6424 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 9 2021 4 13-20 |
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10.21886/2308-6424-2021-9-4-13-20 doi (DE-627)DOAJ030716918 (DE-599)DOAJc09ec8d86df14e41abcd02816c5eaa30 DE-627 ger DE-627 rakwb rus RC870-923 V. B. Berdichevsky verfasserin aut IPET-CT in inflammatory diseases of kidneys and bladder: diagnostic efficacy 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction. The incorporation of combined positron emission tomography-computed tomography (PET-CT) into clinical practice has significantly expanded the understanding of the pathogenesis of many diseases. Evidence-based data on the diagnostic efficacy in infectious and inflammatory diseases is increasing, making this imaging method very promising. Purpose of the study. To study the diagnostic efficacy of 18F-FDG PET-CT in various chronic inflammatory diseases of kidneys and bladder.Materials and methods. A retrospective study of the results of whole-body 18F-FDG PET-CT in 45 patients was carried out. Patients underwent an investigation at various times after surgical treatment of localized oncology of the anogenital zone at the T1N0M0 stage without the involvement of the genitourinary system. It was found that 24 patients had a history of chronic pyelonephritis and 21 patients had manifestations of radiation cystitis. Repeated PET/CT scans were performed after a course of therapy for inflammatory urological diseases to assess the treatment results of the underlying pathology.Results. The latent course of chronic renal failure was accompanied by a diffuse decrease in 18F-FDG metabolism in the renal parenchyma with its partial recovery after etiotropic therapy and urine sanitation. Hypermetabolism of 18F-FDG was detected in the bladder wall during manifestations of radiation cystitis, which was leveled during therapy and relief of urinary syndrome manifestations. Bacterial and radiation inflammation differed in molecular-cell responses to the pathogen, while the results of urinalysis, indicating the effectiveness of the treatment, coincided with the visual and digital indicators of the restoration of adequate energy metabolism in the studied tissues.Conclusions. Metabolism of 18F-FDG in the kidneys and bladder can objectively reflect the nature of inflammation and complement the data on the effectiveness of the treatment. pet- ct 18f-fdg metabolism inflammation kidneys bladder Diseases of the genitourinary system. Urology B. A. Berdichevsky verfasserin aut A. V. Romanova verfasserin aut F. R. Rasulov verfasserin aut A. A. Naletov verfasserin aut S. V. Khilkevich verfasserin aut E. I. Gutrova verfasserin aut A. L. Boldyrev verfasserin aut M. A. Korabelnikov verfasserin aut In Vestnik Urologii State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation, 2018 9(2021), 4, Seite 13-20 (DE-627)176064014X 23086424 nnns volume:9 year:2021 number:4 pages:13-20 https://doi.org/10.21886/2308-6424-2021-9-4-13-20 kostenfrei https://doaj.org/article/c09ec8d86df14e41abcd02816c5eaa30 kostenfrei https://www.urovest.ru/jour/article/view/495 kostenfrei https://doaj.org/toc/2308-6424 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 9 2021 4 13-20 |
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B. Berdichevsky</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">IPET-CT in inflammatory diseases of kidneys and bladder: diagnostic efficacy</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2021</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Introduction. The incorporation of combined positron emission tomography-computed tomography (PET-CT) into clinical practice has significantly expanded the understanding of the pathogenesis of many diseases. Evidence-based data on the diagnostic efficacy in infectious and inflammatory diseases is increasing, making this imaging method very promising. Purpose of the study. To study the diagnostic efficacy of 18F-FDG PET-CT in various chronic inflammatory diseases of kidneys and bladder.Materials and methods. A retrospective study of the results of whole-body 18F-FDG PET-CT in 45 patients was carried out. Patients underwent an investigation at various times after surgical treatment of localized oncology of the anogenital zone at the T1N0M0 stage without the involvement of the genitourinary system. It was found that 24 patients had a history of chronic pyelonephritis and 21 patients had manifestations of radiation cystitis. Repeated PET/CT scans were performed after a course of therapy for inflammatory urological diseases to assess the treatment results of the underlying pathology.Results. The latent course of chronic renal failure was accompanied by a diffuse decrease in 18F-FDG metabolism in the renal parenchyma with its partial recovery after etiotropic therapy and urine sanitation. Hypermetabolism of 18F-FDG was detected in the bladder wall during manifestations of radiation cystitis, which was leveled during therapy and relief of urinary syndrome manifestations. Bacterial and radiation inflammation differed in molecular-cell responses to the pathogen, while the results of urinalysis, indicating the effectiveness of the treatment, coincided with the visual and digital indicators of the restoration of adequate energy metabolism in the studied tissues.Conclusions. 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RC870-923 IPET-CT in inflammatory diseases of kidneys and bladder: diagnostic efficacy pet- ct 18f-fdg metabolism inflammation kidneys bladder |
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V. B. Berdichevsky B. A. Berdichevsky A. V. Romanova F. R. Rasulov A. A. Naletov S. V. Khilkevich E. I. Gutrova A. L. Boldyrev M. A. Korabelnikov |
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ipet-ct in inflammatory diseases of kidneys and bladder: diagnostic efficacy |
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RC870-923 |
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IPET-CT in inflammatory diseases of kidneys and bladder: diagnostic efficacy |
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Introduction. The incorporation of combined positron emission tomography-computed tomography (PET-CT) into clinical practice has significantly expanded the understanding of the pathogenesis of many diseases. Evidence-based data on the diagnostic efficacy in infectious and inflammatory diseases is increasing, making this imaging method very promising. Purpose of the study. To study the diagnostic efficacy of 18F-FDG PET-CT in various chronic inflammatory diseases of kidneys and bladder.Materials and methods. A retrospective study of the results of whole-body 18F-FDG PET-CT in 45 patients was carried out. Patients underwent an investigation at various times after surgical treatment of localized oncology of the anogenital zone at the T1N0M0 stage without the involvement of the genitourinary system. It was found that 24 patients had a history of chronic pyelonephritis and 21 patients had manifestations of radiation cystitis. Repeated PET/CT scans were performed after a course of therapy for inflammatory urological diseases to assess the treatment results of the underlying pathology.Results. The latent course of chronic renal failure was accompanied by a diffuse decrease in 18F-FDG metabolism in the renal parenchyma with its partial recovery after etiotropic therapy and urine sanitation. Hypermetabolism of 18F-FDG was detected in the bladder wall during manifestations of radiation cystitis, which was leveled during therapy and relief of urinary syndrome manifestations. Bacterial and radiation inflammation differed in molecular-cell responses to the pathogen, while the results of urinalysis, indicating the effectiveness of the treatment, coincided with the visual and digital indicators of the restoration of adequate energy metabolism in the studied tissues.Conclusions. Metabolism of 18F-FDG in the kidneys and bladder can objectively reflect the nature of inflammation and complement the data on the effectiveness of the treatment. |
| abstractGer |
Introduction. The incorporation of combined positron emission tomography-computed tomography (PET-CT) into clinical practice has significantly expanded the understanding of the pathogenesis of many diseases. Evidence-based data on the diagnostic efficacy in infectious and inflammatory diseases is increasing, making this imaging method very promising. Purpose of the study. To study the diagnostic efficacy of 18F-FDG PET-CT in various chronic inflammatory diseases of kidneys and bladder.Materials and methods. A retrospective study of the results of whole-body 18F-FDG PET-CT in 45 patients was carried out. Patients underwent an investigation at various times after surgical treatment of localized oncology of the anogenital zone at the T1N0M0 stage without the involvement of the genitourinary system. It was found that 24 patients had a history of chronic pyelonephritis and 21 patients had manifestations of radiation cystitis. Repeated PET/CT scans were performed after a course of therapy for inflammatory urological diseases to assess the treatment results of the underlying pathology.Results. The latent course of chronic renal failure was accompanied by a diffuse decrease in 18F-FDG metabolism in the renal parenchyma with its partial recovery after etiotropic therapy and urine sanitation. Hypermetabolism of 18F-FDG was detected in the bladder wall during manifestations of radiation cystitis, which was leveled during therapy and relief of urinary syndrome manifestations. Bacterial and radiation inflammation differed in molecular-cell responses to the pathogen, while the results of urinalysis, indicating the effectiveness of the treatment, coincided with the visual and digital indicators of the restoration of adequate energy metabolism in the studied tissues.Conclusions. Metabolism of 18F-FDG in the kidneys and bladder can objectively reflect the nature of inflammation and complement the data on the effectiveness of the treatment. |
| abstract_unstemmed |
Introduction. The incorporation of combined positron emission tomography-computed tomography (PET-CT) into clinical practice has significantly expanded the understanding of the pathogenesis of many diseases. Evidence-based data on the diagnostic efficacy in infectious and inflammatory diseases is increasing, making this imaging method very promising. Purpose of the study. To study the diagnostic efficacy of 18F-FDG PET-CT in various chronic inflammatory diseases of kidneys and bladder.Materials and methods. A retrospective study of the results of whole-body 18F-FDG PET-CT in 45 patients was carried out. Patients underwent an investigation at various times after surgical treatment of localized oncology of the anogenital zone at the T1N0M0 stage without the involvement of the genitourinary system. It was found that 24 patients had a history of chronic pyelonephritis and 21 patients had manifestations of radiation cystitis. Repeated PET/CT scans were performed after a course of therapy for inflammatory urological diseases to assess the treatment results of the underlying pathology.Results. The latent course of chronic renal failure was accompanied by a diffuse decrease in 18F-FDG metabolism in the renal parenchyma with its partial recovery after etiotropic therapy and urine sanitation. Hypermetabolism of 18F-FDG was detected in the bladder wall during manifestations of radiation cystitis, which was leveled during therapy and relief of urinary syndrome manifestations. Bacterial and radiation inflammation differed in molecular-cell responses to the pathogen, while the results of urinalysis, indicating the effectiveness of the treatment, coincided with the visual and digital indicators of the restoration of adequate energy metabolism in the studied tissues.Conclusions. Metabolism of 18F-FDG in the kidneys and bladder can objectively reflect the nature of inflammation and complement the data on the effectiveness of the treatment. |
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IPET-CT in inflammatory diseases of kidneys and bladder: diagnostic efficacy |
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