The effect of noni fruit (Morinda citrifolia L.) extract on interleukin 4 and interleukin 10 in Wistar rats, induced by pyrazinamide, ethambutol and levofloxacin

Pyrazinamide, Ethambutol and Levofloxacin are part of the anti-tuberculosis SLD that have many side effects. This response causes an inflammatory reaction that affects pro-inflammatory cytokines interleukin 4 and interleukin 10. Morinda citrifolia L. produces anti-inflammatory activity that affects...
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Gespeichert in:

Autor*in:	Thontowi Djauhari Nur Subchi [verfasserIn] Merryana Andriani [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2019

Schlagwörter:	Morinda citrifolia L. extract, Interleukin 4 (IL-4), Interleukin 10 (IL-10)

Übergeordnetes Werk:	In: Journal of Public Health in Africa - PAGEPress Publications, 2010, 10(2019), 1s
Übergeordnetes Werk:	volume:10 ; year:2019 ; number:1s

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.4081/jphia.2019.1203

Katalog-ID:	DOAJ030835461

Internformat


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allfields	10.4081/jphia.2019.1203 doi (DE-627)DOAJ030835461 (DE-599)DOAJ768fef5402884b98b19eedcc95eaae12 DE-627 ger DE-627 rakwb eng RA1-1270 Thontowi Djauhari Nur Subchi verfasserin aut The effect of noni fruit (Morinda citrifolia L.) extract on interleukin 4 and interleukin 10 in Wistar rats, induced by pyrazinamide, ethambutol and levofloxacin 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Pyrazinamide, Ethambutol and Levofloxacin are part of the anti-tuberculosis SLD that have many side effects. This response causes an inflammatory reaction that affects pro-inflammatory cytokines interleukin 4 and interleukin 10. Morinda citrifolia L. produces anti-inflammatory activity that affects cytokines and provides protection against cell damage. A dose therapy was administered to wistar rats for two months, grouped in K- (negative control), K+ (positive control), MI (drug + Morinda citrifolia L. extract, dose of 100 mg/kg body weight), MII (drug + noni fruit extract, dose of 200 mg/kg body weight) and MIII (drug + noni fruit extract, dose of 400 mg/kg body weight). Results were examined using Rat IL-4 and IL-10 immunoassay Quantikine ELISA kits. The ANOVA (Analysis of Variance) test results showed that there was an overall IL-4 difference (sig<0.05); for IL-10 there was no great difference (sig<0.05); it was decrease trend was shown in MI and MII. However, by giving Morinda citrifolia L. extracts can significantly influence the IL-4 and IL-10, with a decreasing trend in MI and MII. Morinda citrifolia L. extract, Interleukin 4 (IL-4), Interleukin 10 (IL-10) Public aspects of medicine Merryana Andriani verfasserin aut In Journal of Public Health in Africa PAGEPress Publications, 2010 10(2019), 1s (DE-627)640380166 (DE-600)2574977-8 20389930 nnns volume:10 year:2019 number:1s https://doi.org/10.4081/jphia.2019.1203 kostenfrei https://doaj.org/article/768fef5402884b98b19eedcc95eaae12 kostenfrei https://www.publichealthinafrica.org/index.php/jphia/article/view/1203 kostenfrei https://doaj.org/toc/2038-9922 Journal toc kostenfrei https://doaj.org/toc/2038-9930 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2019 1s
spelling	10.4081/jphia.2019.1203 doi (DE-627)DOAJ030835461 (DE-599)DOAJ768fef5402884b98b19eedcc95eaae12 DE-627 ger DE-627 rakwb eng RA1-1270 Thontowi Djauhari Nur Subchi verfasserin aut The effect of noni fruit (Morinda citrifolia L.) extract on interleukin 4 and interleukin 10 in Wistar rats, induced by pyrazinamide, ethambutol and levofloxacin 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Pyrazinamide, Ethambutol and Levofloxacin are part of the anti-tuberculosis SLD that have many side effects. This response causes an inflammatory reaction that affects pro-inflammatory cytokines interleukin 4 and interleukin 10. Morinda citrifolia L. produces anti-inflammatory activity that affects cytokines and provides protection against cell damage. A dose therapy was administered to wistar rats for two months, grouped in K- (negative control), K+ (positive control), MI (drug + Morinda citrifolia L. extract, dose of 100 mg/kg body weight), MII (drug + noni fruit extract, dose of 200 mg/kg body weight) and MIII (drug + noni fruit extract, dose of 400 mg/kg body weight). Results were examined using Rat IL-4 and IL-10 immunoassay Quantikine ELISA kits. The ANOVA (Analysis of Variance) test results showed that there was an overall IL-4 difference (sig<0.05); for IL-10 there was no great difference (sig<0.05); it was decrease trend was shown in MI and MII. However, by giving Morinda citrifolia L. extracts can significantly influence the IL-4 and IL-10, with a decreasing trend in MI and MII. Morinda citrifolia L. extract, Interleukin 4 (IL-4), Interleukin 10 (IL-10) Public aspects of medicine Merryana Andriani verfasserin aut In Journal of Public Health in Africa PAGEPress Publications, 2010 10(2019), 1s (DE-627)640380166 (DE-600)2574977-8 20389930 nnns volume:10 year:2019 number:1s https://doi.org/10.4081/jphia.2019.1203 kostenfrei https://doaj.org/article/768fef5402884b98b19eedcc95eaae12 kostenfrei https://www.publichealthinafrica.org/index.php/jphia/article/view/1203 kostenfrei https://doaj.org/toc/2038-9922 Journal toc kostenfrei https://doaj.org/toc/2038-9930 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2019 1s
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allfieldsGer	10.4081/jphia.2019.1203 doi (DE-627)DOAJ030835461 (DE-599)DOAJ768fef5402884b98b19eedcc95eaae12 DE-627 ger DE-627 rakwb eng RA1-1270 Thontowi Djauhari Nur Subchi verfasserin aut The effect of noni fruit (Morinda citrifolia L.) extract on interleukin 4 and interleukin 10 in Wistar rats, induced by pyrazinamide, ethambutol and levofloxacin 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Pyrazinamide, Ethambutol and Levofloxacin are part of the anti-tuberculosis SLD that have many side effects. This response causes an inflammatory reaction that affects pro-inflammatory cytokines interleukin 4 and interleukin 10. Morinda citrifolia L. produces anti-inflammatory activity that affects cytokines and provides protection against cell damage. A dose therapy was administered to wistar rats for two months, grouped in K- (negative control), K+ (positive control), MI (drug + Morinda citrifolia L. extract, dose of 100 mg/kg body weight), MII (drug + noni fruit extract, dose of 200 mg/kg body weight) and MIII (drug + noni fruit extract, dose of 400 mg/kg body weight). Results were examined using Rat IL-4 and IL-10 immunoassay Quantikine ELISA kits. The ANOVA (Analysis of Variance) test results showed that there was an overall IL-4 difference (sig<0.05); for IL-10 there was no great difference (sig<0.05); it was decrease trend was shown in MI and MII. However, by giving Morinda citrifolia L. extracts can significantly influence the IL-4 and IL-10, with a decreasing trend in MI and MII. Morinda citrifolia L. extract, Interleukin 4 (IL-4), Interleukin 10 (IL-10) Public aspects of medicine Merryana Andriani verfasserin aut In Journal of Public Health in Africa PAGEPress Publications, 2010 10(2019), 1s (DE-627)640380166 (DE-600)2574977-8 20389930 nnns volume:10 year:2019 number:1s https://doi.org/10.4081/jphia.2019.1203 kostenfrei https://doaj.org/article/768fef5402884b98b19eedcc95eaae12 kostenfrei https://www.publichealthinafrica.org/index.php/jphia/article/view/1203 kostenfrei https://doaj.org/toc/2038-9922 Journal toc kostenfrei https://doaj.org/toc/2038-9930 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2019 1s
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callnumber-first	R - Medicine
author	Thontowi Djauhari Nur Subchi
spellingShingle	Thontowi Djauhari Nur Subchi misc RA1-1270 misc Morinda citrifolia L. extract, Interleukin 4 (IL-4), Interleukin 10 (IL-10) misc Public aspects of medicine The effect of noni fruit (Morinda citrifolia L.) extract on interleukin 4 and interleukin 10 in Wistar rats, induced by pyrazinamide, ethambutol and levofloxacin
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topic_title	RA1-1270 The effect of noni fruit (Morinda citrifolia L.) extract on interleukin 4 and interleukin 10 in Wistar rats, induced by pyrazinamide, ethambutol and levofloxacin Morinda citrifolia L. extract, Interleukin 4 (IL-4), Interleukin 10 (IL-10)
topic	misc RA1-1270 misc Morinda citrifolia L. extract, Interleukin 4 (IL-4), Interleukin 10 (IL-10) misc Public aspects of medicine
topic_unstemmed	misc RA1-1270 misc Morinda citrifolia L. extract, Interleukin 4 (IL-4), Interleukin 10 (IL-10) misc Public aspects of medicine
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title	The effect of noni fruit (Morinda citrifolia L.) extract on interleukin 4 and interleukin 10 in Wistar rats, induced by pyrazinamide, ethambutol and levofloxacin
ctrlnum	(DE-627)DOAJ030835461 (DE-599)DOAJ768fef5402884b98b19eedcc95eaae12
title_full	The effect of noni fruit (Morinda citrifolia L.) extract on interleukin 4 and interleukin 10 in Wistar rats, induced by pyrazinamide, ethambutol and levofloxacin
author_sort	Thontowi Djauhari Nur Subchi
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author_browse	Thontowi Djauhari Nur Subchi Merryana Andriani
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title_sort	effect of noni fruit (morinda citrifolia l.) extract on interleukin 4 and interleukin 10 in wistar rats, induced by pyrazinamide, ethambutol and levofloxacin
callnumber	RA1-1270
title_auth	The effect of noni fruit (Morinda citrifolia L.) extract on interleukin 4 and interleukin 10 in Wistar rats, induced by pyrazinamide, ethambutol and levofloxacin
abstract	Pyrazinamide, Ethambutol and Levofloxacin are part of the anti-tuberculosis SLD that have many side effects. This response causes an inflammatory reaction that affects pro-inflammatory cytokines interleukin 4 and interleukin 10. Morinda citrifolia L. produces anti-inflammatory activity that affects cytokines and provides protection against cell damage. A dose therapy was administered to wistar rats for two months, grouped in K- (negative control), K+ (positive control), MI (drug + Morinda citrifolia L. extract, dose of 100 mg/kg body weight), MII (drug + noni fruit extract, dose of 200 mg/kg body weight) and MIII (drug + noni fruit extract, dose of 400 mg/kg body weight). Results were examined using Rat IL-4 and IL-10 immunoassay Quantikine ELISA kits. The ANOVA (Analysis of Variance) test results showed that there was an overall IL-4 difference (sig<0.05); for IL-10 there was no great difference (sig<0.05); it was decrease trend was shown in MI and MII. However, by giving Morinda citrifolia L. extracts can significantly influence the IL-4 and IL-10, with a decreasing trend in MI and MII.
abstractGer	Pyrazinamide, Ethambutol and Levofloxacin are part of the anti-tuberculosis SLD that have many side effects. This response causes an inflammatory reaction that affects pro-inflammatory cytokines interleukin 4 and interleukin 10. Morinda citrifolia L. produces anti-inflammatory activity that affects cytokines and provides protection against cell damage. A dose therapy was administered to wistar rats for two months, grouped in K- (negative control), K+ (positive control), MI (drug + Morinda citrifolia L. extract, dose of 100 mg/kg body weight), MII (drug + noni fruit extract, dose of 200 mg/kg body weight) and MIII (drug + noni fruit extract, dose of 400 mg/kg body weight). Results were examined using Rat IL-4 and IL-10 immunoassay Quantikine ELISA kits. The ANOVA (Analysis of Variance) test results showed that there was an overall IL-4 difference (sig<0.05); for IL-10 there was no great difference (sig<0.05); it was decrease trend was shown in MI and MII. However, by giving Morinda citrifolia L. extracts can significantly influence the IL-4 and IL-10, with a decreasing trend in MI and MII.
abstract_unstemmed	Pyrazinamide, Ethambutol and Levofloxacin are part of the anti-tuberculosis SLD that have many side effects. This response causes an inflammatory reaction that affects pro-inflammatory cytokines interleukin 4 and interleukin 10. Morinda citrifolia L. produces anti-inflammatory activity that affects cytokines and provides protection against cell damage. A dose therapy was administered to wistar rats for two months, grouped in K- (negative control), K+ (positive control), MI (drug + Morinda citrifolia L. extract, dose of 100 mg/kg body weight), MII (drug + noni fruit extract, dose of 200 mg/kg body weight) and MIII (drug + noni fruit extract, dose of 400 mg/kg body weight). Results were examined using Rat IL-4 and IL-10 immunoassay Quantikine ELISA kits. The ANOVA (Analysis of Variance) test results showed that there was an overall IL-4 difference (sig<0.05); for IL-10 there was no great difference (sig<0.05); it was decrease trend was shown in MI and MII. However, by giving Morinda citrifolia L. extracts can significantly influence the IL-4 and IL-10, with a decreasing trend in MI and MII.
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title_short	The effect of noni fruit (Morinda citrifolia L.) extract on interleukin 4 and interleukin 10 in Wistar rats, induced by pyrazinamide, ethambutol and levofloxacin
url	https://doi.org/10.4081/jphia.2019.1203 https://doaj.org/article/768fef5402884b98b19eedcc95eaae12 https://www.publichealthinafrica.org/index.php/jphia/article/view/1203 https://doaj.org/toc/2038-9922 https://doaj.org/toc/2038-9930
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up_date	2024-07-03T17:14:09.260Z
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The effect of noni fruit (Morinda citrifolia L.) extract on interleukin 4 and interleukin 10 in Wistar rats, induced by pyrazinamide, ethambutol and levofloxacin

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