Analysis of the combined effect of polymorphisms interferon genes OAS1, OAS3, PKR, IFNA17 and IFNG in susceptibility to chronic viral hepatitis C
Interferon system plays a key role in the antiviral response. Based on data from the literature, the most dangerous for the development of infectious diseases is the combination of risk alleles of several genes. This study focuses on the analysis of the combined effect of single nucleotide polymorph...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
V. A. Bychkov [verfasserIn] N. V. Ryazantseva [verfasserIn] V. V. Novitsky [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch ; Russisch |
| Erschienen: |
2011 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
In: Бюллетень сибирской медицины - Siberian State Medical University (Tomsk), 2016, 10(2011), 3, Seite 19-23 |
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| Übergeordnetes Werk: |
volume:10 ; year:2011 ; number:3 ; pages:19-23 |
| Links: |
Link aufrufen |
|---|
| DOI / URN: |
10.20538/1682-0363-2011-3-19-23 |
|---|
| Katalog-ID: |
DOAJ031134998 |
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Analysis of the combined effect of polymorphisms interferon genes OAS1, OAS3, PKR, IFNA17 and IFNG in susceptibility to chronic viral hepatitis C интерферон однонуклеотидные полиморфизмы хронический вирусный гепатит c прогнозные модели |
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Analysis of the combined effect of polymorphisms interferon genes OAS1, OAS3, PKR, IFNA17 and IFNG in susceptibility to chronic viral hepatitis C |
| abstract |
Interferon system plays a key role in the antiviral response. Based on data from the literature, the most dangerous for the development of infectious diseases is the combination of risk alleles of several genes. This study focuses on the analysis of the combined effect of single nucleotide polymorphisms of interferon system genes OAS1, OAS3, PKR, IFNA17 and IFNG in the predisposition to chronic viral hepatitis C. It has been shown that the accounting of several risk genes improves the prediction of development of this disease. |
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Interferon system plays a key role in the antiviral response. Based on data from the literature, the most dangerous for the development of infectious diseases is the combination of risk alleles of several genes. This study focuses on the analysis of the combined effect of single nucleotide polymorphisms of interferon system genes OAS1, OAS3, PKR, IFNA17 and IFNG in the predisposition to chronic viral hepatitis C. It has been shown that the accounting of several risk genes improves the prediction of development of this disease. |
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Interferon system plays a key role in the antiviral response. Based on data from the literature, the most dangerous for the development of infectious diseases is the combination of risk alleles of several genes. This study focuses on the analysis of the combined effect of single nucleotide polymorphisms of interferon system genes OAS1, OAS3, PKR, IFNA17 and IFNG in the predisposition to chronic viral hepatitis C. It has been shown that the accounting of several risk genes improves the prediction of development of this disease. |
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Analysis of the combined effect of polymorphisms interferon genes OAS1, OAS3, PKR, IFNA17 and IFNG in susceptibility to chronic viral hepatitis C |
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https://doi.org/10.20538/1682-0363-2011-3-19-23 https://doaj.org/article/f9892aab56cb4d63b6825739b4169a15 https://bulletin.ssmu.ru/jour/article/view/1386 https://doaj.org/toc/1682-0363 https://doaj.org/toc/1819-3684 |
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N. V. Ryazantseva V. V. Novitsky |
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10.20538/1682-0363-2011-3-19-23 |
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