Genome-Wide Association Studies in Myocardial Infarction and Coronary Artery Disease

Myocardial infarction (MI) and its major determinant, coronary artery disease (CAD), are complex diseases arising from the interaction between several genetic and environmental factors. Until recently, the genetic basis of these diseases was poorly understood. Genome-wide genetic association studies...
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Autor*in:	Pier Mannucci [verfasserIn] Luca Lotta [verfasserIn] Flora Peyvandi [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2010

Schlagwörter:	Genome-wide association study Myocardial infarction Coronary artery disease

Übergeordnetes Werk:	In: Journal of Tehran University Heart Center - Tehran University of Medical Sciences, 2020, 5(2010), 3
Übergeordnetes Werk:	volume:5 ; year:2010 ; number:3

Links:	Link aufrufen Link aufrufen Journal toc Journal toc

Katalog-ID:	DOAJ031497101

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spelling	(DE-627)DOAJ031497101 (DE-599)DOAJ8461a68c1113403ea5db1a5bf24b4ed2 DE-627 ger DE-627 rakwb eng RC666-701 Pier Mannucci verfasserin aut Genome-Wide Association Studies in Myocardial Infarction and Coronary Artery Disease 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Myocardial infarction (MI) and its major determinant, coronary artery disease (CAD), are complex diseases arising from the interaction between several genetic and environmental factors. Until recently, the genetic basis of these diseases was poorly understood. Genome-wide genetic association studies have afforded a comprehensive insight into the association between genetic variants and diseases. To date, seven genome-wide association studies have been conducted in CAD/MI, identifying thirteen genomic regions at which common genetic variants influence the predisposition to these diseases. This review article summarizes the progress achieved in the genetic basis of MI and CAD by means of genome-wide association studies and the potential clinical applications of these findings. Genome-wide association study Myocardial infarction Coronary artery disease Diseases of the circulatory (Cardiovascular) system Luca Lotta verfasserin aut Flora Peyvandi verfasserin aut In Journal of Tehran University Heart Center Tehran University of Medical Sciences, 2020 5(2010), 3 (DE-627)590956302 (DE-600)2476998-8 20082371 nnns volume:5 year:2010 number:3 https://doaj.org/article/8461a68c1113403ea5db1a5bf24b4ed2 kostenfrei https://jthc.tums.ac.ir/index.php/jthc/article/view/173 kostenfrei https://doaj.org/toc/1735-8620 Journal toc kostenfrei https://doaj.org/toc/2008-2371 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 5 2010 3
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allfieldsSound	(DE-627)DOAJ031497101 (DE-599)DOAJ8461a68c1113403ea5db1a5bf24b4ed2 DE-627 ger DE-627 rakwb eng RC666-701 Pier Mannucci verfasserin aut Genome-Wide Association Studies in Myocardial Infarction and Coronary Artery Disease 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Myocardial infarction (MI) and its major determinant, coronary artery disease (CAD), are complex diseases arising from the interaction between several genetic and environmental factors. Until recently, the genetic basis of these diseases was poorly understood. Genome-wide genetic association studies have afforded a comprehensive insight into the association between genetic variants and diseases. To date, seven genome-wide association studies have been conducted in CAD/MI, identifying thirteen genomic regions at which common genetic variants influence the predisposition to these diseases. This review article summarizes the progress achieved in the genetic basis of MI and CAD by means of genome-wide association studies and the potential clinical applications of these findings. Genome-wide association study Myocardial infarction Coronary artery disease Diseases of the circulatory (Cardiovascular) system Luca Lotta verfasserin aut Flora Peyvandi verfasserin aut In Journal of Tehran University Heart Center Tehran University of Medical Sciences, 2020 5(2010), 3 (DE-627)590956302 (DE-600)2476998-8 20082371 nnns volume:5 year:2010 number:3 https://doaj.org/article/8461a68c1113403ea5db1a5bf24b4ed2 kostenfrei https://jthc.tums.ac.ir/index.php/jthc/article/view/173 kostenfrei https://doaj.org/toc/1735-8620 Journal toc kostenfrei https://doaj.org/toc/2008-2371 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 5 2010 3
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callnumber-first	R - Medicine
author	Pier Mannucci
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topic_title	RC666-701 Genome-Wide Association Studies in Myocardial Infarction and Coronary Artery Disease Genome-wide association study Myocardial infarction Coronary artery disease
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title	Genome-Wide Association Studies in Myocardial Infarction and Coronary Artery Disease
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title_sort	genome-wide association studies in myocardial infarction and coronary artery disease
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title_auth	Genome-Wide Association Studies in Myocardial Infarction and Coronary Artery Disease
abstract	Myocardial infarction (MI) and its major determinant, coronary artery disease (CAD), are complex diseases arising from the interaction between several genetic and environmental factors. Until recently, the genetic basis of these diseases was poorly understood. Genome-wide genetic association studies have afforded a comprehensive insight into the association between genetic variants and diseases. To date, seven genome-wide association studies have been conducted in CAD/MI, identifying thirteen genomic regions at which common genetic variants influence the predisposition to these diseases. This review article summarizes the progress achieved in the genetic basis of MI and CAD by means of genome-wide association studies and the potential clinical applications of these findings.
abstractGer	Myocardial infarction (MI) and its major determinant, coronary artery disease (CAD), are complex diseases arising from the interaction between several genetic and environmental factors. Until recently, the genetic basis of these diseases was poorly understood. Genome-wide genetic association studies have afforded a comprehensive insight into the association between genetic variants and diseases. To date, seven genome-wide association studies have been conducted in CAD/MI, identifying thirteen genomic regions at which common genetic variants influence the predisposition to these diseases. This review article summarizes the progress achieved in the genetic basis of MI and CAD by means of genome-wide association studies and the potential clinical applications of these findings.
abstract_unstemmed	Myocardial infarction (MI) and its major determinant, coronary artery disease (CAD), are complex diseases arising from the interaction between several genetic and environmental factors. Until recently, the genetic basis of these diseases was poorly understood. Genome-wide genetic association studies have afforded a comprehensive insight into the association between genetic variants and diseases. To date, seven genome-wide association studies have been conducted in CAD/MI, identifying thirteen genomic regions at which common genetic variants influence the predisposition to these diseases. This review article summarizes the progress achieved in the genetic basis of MI and CAD by means of genome-wide association studies and the potential clinical applications of these findings.
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title_short	Genome-Wide Association Studies in Myocardial Infarction and Coronary Artery Disease
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