Paraneoplastic Sjogren’s syndrome in gastric cancer
In clinical practice, various masks of oncological diseases are often found. Some of them can manifest as a variety of syndromes or symptom complexes that resemble many non-oncologic diseases, including diffuse connective tissue diseases. In some cases, paraneoplastic syndrome facilitates diagnosing...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
R F Khamitov [verfasserIn] A F Molostvova [verfasserIn] L M Salimova [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Russisch |
| Erschienen: |
2018 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
In: Kazanskij Medicinskij Žurnal - ECO-vector, 2018, 99(2018), 2, Seite 301-304 |
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| Übergeordnetes Werk: |
volume:99 ; year:2018 ; number:2 ; pages:301-304 |
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Link aufrufen |
|---|
| DOI / URN: |
10.17816/KMJ2018-301 |
|---|
| Katalog-ID: |
DOAJ031862969 |
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| 520 | |a In clinical practice, various masks of oncological diseases are often found. Some of them can manifest as a variety of syndromes or symptom complexes that resemble many non-oncologic diseases, including diffuse connective tissue diseases. In some cases, paraneoplastic syndrome facilitates diagnosing a malignant neoplasm in the early stages, but, unfortunately, can also mimic the tumor process by its more prominent manifestations, which lead to late establishment of the true cause of the disease, and therefore postpone specific treatment, creating significant clinical problems. Aim of the study was to reveal pathogenetic relationship between cancer and paraneoplastic syndrome on the example of our clinical observation. A clinical case of diagnosed paraneoplastic syndrome in the form of secondary Sjogren's syndrome, which developed long before the diagnosis of stomach cancer was made, as well as the results of clinical, instrumental, and laboratory examination of the patient, are presented. Questions of epidemiology, etiopathogenesis, and clinical picture of paraneoplastic syndrome are covered. The presented clinical case made it possible to outline the features of the course of paraneoplastic Sjogren's syndrome in gastric cancer and to identify a number of criteria for the diagnostic algorithm of this nosology. In particular, such criteria include general pathogenetic mechanisms, development only in malignant tumors, nonspecific clinical and laboratory manifestations, lack of parallelism with local symptoms of the tumor, the possibility of occurrence of paraneoplastic Sjogren's syndrome before development of local tumor symptoms and reappearance after its relapse. Oncologic diseases are characterized not only by specific symptoms characteristic for a certain organ damage (pain, bleeding, dysfunction, etc.), but also by a variety of nonspecific manifestations (fatigue, subfebrile temperature, weight loss, etc.) regardless of the nature, location and prevalence of the tumor process. | ||
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10.17816/KMJ2018-301 doi (DE-627)DOAJ031862969 (DE-599)DOAJ07471d14ea9448099639468d3b06d1eb DE-627 ger DE-627 rakwb rus R F Khamitov verfasserin aut Paraneoplastic Sjogren’s syndrome in gastric cancer 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier In clinical practice, various masks of oncological diseases are often found. Some of them can manifest as a variety of syndromes or symptom complexes that resemble many non-oncologic diseases, including diffuse connective tissue diseases. In some cases, paraneoplastic syndrome facilitates diagnosing a malignant neoplasm in the early stages, but, unfortunately, can also mimic the tumor process by its more prominent manifestations, which lead to late establishment of the true cause of the disease, and therefore postpone specific treatment, creating significant clinical problems. Aim of the study was to reveal pathogenetic relationship between cancer and paraneoplastic syndrome on the example of our clinical observation. A clinical case of diagnosed paraneoplastic syndrome in the form of secondary Sjogren's syndrome, which developed long before the diagnosis of stomach cancer was made, as well as the results of clinical, instrumental, and laboratory examination of the patient, are presented. Questions of epidemiology, etiopathogenesis, and clinical picture of paraneoplastic syndrome are covered. The presented clinical case made it possible to outline the features of the course of paraneoplastic Sjogren's syndrome in gastric cancer and to identify a number of criteria for the diagnostic algorithm of this nosology. In particular, such criteria include general pathogenetic mechanisms, development only in malignant tumors, nonspecific clinical and laboratory manifestations, lack of parallelism with local symptoms of the tumor, the possibility of occurrence of paraneoplastic Sjogren's syndrome before development of local tumor symptoms and reappearance after its relapse. Oncologic diseases are characterized not only by specific symptoms characteristic for a certain organ damage (pain, bleeding, dysfunction, etc.), but also by a variety of nonspecific manifestations (fatigue, subfebrile temperature, weight loss, etc.) regardless of the nature, location and prevalence of the tumor process. паранеопластический синдром рак желудка синдром Шёгрена Medicine R A F Molostvova verfasserin aut L M Salimova verfasserin aut In Kazanskij Medicinskij Žurnal ECO-vector, 2018 99(2018), 2, Seite 301-304 (DE-627)1760612359 25879359 nnns volume:99 year:2018 number:2 pages:301-304 https://doi.org/10.17816/KMJ2018-301 kostenfrei https://doaj.org/article/07471d14ea9448099639468d3b06d1eb kostenfrei https://journals.eco-vector.com/kazanmedj/article/view/8424 kostenfrei https://doaj.org/toc/0368-4814 Journal toc kostenfrei https://doaj.org/toc/2587-9359 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 99 2018 2 301-304 |
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10.17816/KMJ2018-301 doi (DE-627)DOAJ031862969 (DE-599)DOAJ07471d14ea9448099639468d3b06d1eb DE-627 ger DE-627 rakwb rus R F Khamitov verfasserin aut Paraneoplastic Sjogren’s syndrome in gastric cancer 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier In clinical practice, various masks of oncological diseases are often found. Some of them can manifest as a variety of syndromes or symptom complexes that resemble many non-oncologic diseases, including diffuse connective tissue diseases. In some cases, paraneoplastic syndrome facilitates diagnosing a malignant neoplasm in the early stages, but, unfortunately, can also mimic the tumor process by its more prominent manifestations, which lead to late establishment of the true cause of the disease, and therefore postpone specific treatment, creating significant clinical problems. Aim of the study was to reveal pathogenetic relationship between cancer and paraneoplastic syndrome on the example of our clinical observation. A clinical case of diagnosed paraneoplastic syndrome in the form of secondary Sjogren's syndrome, which developed long before the diagnosis of stomach cancer was made, as well as the results of clinical, instrumental, and laboratory examination of the patient, are presented. Questions of epidemiology, etiopathogenesis, and clinical picture of paraneoplastic syndrome are covered. The presented clinical case made it possible to outline the features of the course of paraneoplastic Sjogren's syndrome in gastric cancer and to identify a number of criteria for the diagnostic algorithm of this nosology. In particular, such criteria include general pathogenetic mechanisms, development only in malignant tumors, nonspecific clinical and laboratory manifestations, lack of parallelism with local symptoms of the tumor, the possibility of occurrence of paraneoplastic Sjogren's syndrome before development of local tumor symptoms and reappearance after its relapse. Oncologic diseases are characterized not only by specific symptoms characteristic for a certain organ damage (pain, bleeding, dysfunction, etc.), but also by a variety of nonspecific manifestations (fatigue, subfebrile temperature, weight loss, etc.) regardless of the nature, location and prevalence of the tumor process. паранеопластический синдром рак желудка синдром Шёгрена Medicine R A F Molostvova verfasserin aut L M Salimova verfasserin aut In Kazanskij Medicinskij Žurnal ECO-vector, 2018 99(2018), 2, Seite 301-304 (DE-627)1760612359 25879359 nnns volume:99 year:2018 number:2 pages:301-304 https://doi.org/10.17816/KMJ2018-301 kostenfrei https://doaj.org/article/07471d14ea9448099639468d3b06d1eb kostenfrei https://journals.eco-vector.com/kazanmedj/article/view/8424 kostenfrei https://doaj.org/toc/0368-4814 Journal toc kostenfrei https://doaj.org/toc/2587-9359 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 99 2018 2 301-304 |
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10.17816/KMJ2018-301 doi (DE-627)DOAJ031862969 (DE-599)DOAJ07471d14ea9448099639468d3b06d1eb DE-627 ger DE-627 rakwb rus R F Khamitov verfasserin aut Paraneoplastic Sjogren’s syndrome in gastric cancer 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier In clinical practice, various masks of oncological diseases are often found. Some of them can manifest as a variety of syndromes or symptom complexes that resemble many non-oncologic diseases, including diffuse connective tissue diseases. In some cases, paraneoplastic syndrome facilitates diagnosing a malignant neoplasm in the early stages, but, unfortunately, can also mimic the tumor process by its more prominent manifestations, which lead to late establishment of the true cause of the disease, and therefore postpone specific treatment, creating significant clinical problems. Aim of the study was to reveal pathogenetic relationship between cancer and paraneoplastic syndrome on the example of our clinical observation. A clinical case of diagnosed paraneoplastic syndrome in the form of secondary Sjogren's syndrome, which developed long before the diagnosis of stomach cancer was made, as well as the results of clinical, instrumental, and laboratory examination of the patient, are presented. Questions of epidemiology, etiopathogenesis, and clinical picture of paraneoplastic syndrome are covered. The presented clinical case made it possible to outline the features of the course of paraneoplastic Sjogren's syndrome in gastric cancer and to identify a number of criteria for the diagnostic algorithm of this nosology. In particular, such criteria include general pathogenetic mechanisms, development only in malignant tumors, nonspecific clinical and laboratory manifestations, lack of parallelism with local symptoms of the tumor, the possibility of occurrence of paraneoplastic Sjogren's syndrome before development of local tumor symptoms and reappearance after its relapse. Oncologic diseases are characterized not only by specific symptoms characteristic for a certain organ damage (pain, bleeding, dysfunction, etc.), but also by a variety of nonspecific manifestations (fatigue, subfebrile temperature, weight loss, etc.) regardless of the nature, location and prevalence of the tumor process. паранеопластический синдром рак желудка синдром Шёгрена Medicine R A F Molostvova verfasserin aut L M Salimova verfasserin aut In Kazanskij Medicinskij Žurnal ECO-vector, 2018 99(2018), 2, Seite 301-304 (DE-627)1760612359 25879359 nnns volume:99 year:2018 number:2 pages:301-304 https://doi.org/10.17816/KMJ2018-301 kostenfrei https://doaj.org/article/07471d14ea9448099639468d3b06d1eb kostenfrei https://journals.eco-vector.com/kazanmedj/article/view/8424 kostenfrei https://doaj.org/toc/0368-4814 Journal toc kostenfrei https://doaj.org/toc/2587-9359 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 99 2018 2 301-304 |
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10.17816/KMJ2018-301 doi (DE-627)DOAJ031862969 (DE-599)DOAJ07471d14ea9448099639468d3b06d1eb DE-627 ger DE-627 rakwb rus R F Khamitov verfasserin aut Paraneoplastic Sjogren’s syndrome in gastric cancer 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier In clinical practice, various masks of oncological diseases are often found. Some of them can manifest as a variety of syndromes or symptom complexes that resemble many non-oncologic diseases, including diffuse connective tissue diseases. In some cases, paraneoplastic syndrome facilitates diagnosing a malignant neoplasm in the early stages, but, unfortunately, can also mimic the tumor process by its more prominent manifestations, which lead to late establishment of the true cause of the disease, and therefore postpone specific treatment, creating significant clinical problems. Aim of the study was to reveal pathogenetic relationship between cancer and paraneoplastic syndrome on the example of our clinical observation. A clinical case of diagnosed paraneoplastic syndrome in the form of secondary Sjogren's syndrome, which developed long before the diagnosis of stomach cancer was made, as well as the results of clinical, instrumental, and laboratory examination of the patient, are presented. Questions of epidemiology, etiopathogenesis, and clinical picture of paraneoplastic syndrome are covered. The presented clinical case made it possible to outline the features of the course of paraneoplastic Sjogren's syndrome in gastric cancer and to identify a number of criteria for the diagnostic algorithm of this nosology. In particular, such criteria include general pathogenetic mechanisms, development only in malignant tumors, nonspecific clinical and laboratory manifestations, lack of parallelism with local symptoms of the tumor, the possibility of occurrence of paraneoplastic Sjogren's syndrome before development of local tumor symptoms and reappearance after its relapse. Oncologic diseases are characterized not only by specific symptoms characteristic for a certain organ damage (pain, bleeding, dysfunction, etc.), but also by a variety of nonspecific manifestations (fatigue, subfebrile temperature, weight loss, etc.) regardless of the nature, location and prevalence of the tumor process. паранеопластический синдром рак желудка синдром Шёгрена Medicine R A F Molostvova verfasserin aut L M Salimova verfasserin aut In Kazanskij Medicinskij Žurnal ECO-vector, 2018 99(2018), 2, Seite 301-304 (DE-627)1760612359 25879359 nnns volume:99 year:2018 number:2 pages:301-304 https://doi.org/10.17816/KMJ2018-301 kostenfrei https://doaj.org/article/07471d14ea9448099639468d3b06d1eb kostenfrei https://journals.eco-vector.com/kazanmedj/article/view/8424 kostenfrei https://doaj.org/toc/0368-4814 Journal toc kostenfrei https://doaj.org/toc/2587-9359 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 99 2018 2 301-304 |
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10.17816/KMJ2018-301 doi (DE-627)DOAJ031862969 (DE-599)DOAJ07471d14ea9448099639468d3b06d1eb DE-627 ger DE-627 rakwb rus R F Khamitov verfasserin aut Paraneoplastic Sjogren’s syndrome in gastric cancer 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier In clinical practice, various masks of oncological diseases are often found. Some of them can manifest as a variety of syndromes or symptom complexes that resemble many non-oncologic diseases, including diffuse connective tissue diseases. In some cases, paraneoplastic syndrome facilitates diagnosing a malignant neoplasm in the early stages, but, unfortunately, can also mimic the tumor process by its more prominent manifestations, which lead to late establishment of the true cause of the disease, and therefore postpone specific treatment, creating significant clinical problems. Aim of the study was to reveal pathogenetic relationship between cancer and paraneoplastic syndrome on the example of our clinical observation. A clinical case of diagnosed paraneoplastic syndrome in the form of secondary Sjogren's syndrome, which developed long before the diagnosis of stomach cancer was made, as well as the results of clinical, instrumental, and laboratory examination of the patient, are presented. Questions of epidemiology, etiopathogenesis, and clinical picture of paraneoplastic syndrome are covered. The presented clinical case made it possible to outline the features of the course of paraneoplastic Sjogren's syndrome in gastric cancer and to identify a number of criteria for the diagnostic algorithm of this nosology. In particular, such criteria include general pathogenetic mechanisms, development only in malignant tumors, nonspecific clinical and laboratory manifestations, lack of parallelism with local symptoms of the tumor, the possibility of occurrence of paraneoplastic Sjogren's syndrome before development of local tumor symptoms and reappearance after its relapse. Oncologic diseases are characterized not only by specific symptoms characteristic for a certain organ damage (pain, bleeding, dysfunction, etc.), but also by a variety of nonspecific manifestations (fatigue, subfebrile temperature, weight loss, etc.) regardless of the nature, location and prevalence of the tumor process. паранеопластический синдром рак желудка синдром Шёгрена Medicine R A F Molostvova verfasserin aut L M Salimova verfasserin aut In Kazanskij Medicinskij Žurnal ECO-vector, 2018 99(2018), 2, Seite 301-304 (DE-627)1760612359 25879359 nnns volume:99 year:2018 number:2 pages:301-304 https://doi.org/10.17816/KMJ2018-301 kostenfrei https://doaj.org/article/07471d14ea9448099639468d3b06d1eb kostenfrei https://journals.eco-vector.com/kazanmedj/article/view/8424 kostenfrei https://doaj.org/toc/0368-4814 Journal toc kostenfrei https://doaj.org/toc/2587-9359 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 99 2018 2 301-304 |
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Paraneoplastic Sjogren’s syndrome in gastric cancer |
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Paraneoplastic Sjogren’s syndrome in gastric cancer |
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R F Khamitov |
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paraneoplastic sjogren’s syndrome in gastric cancer |
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Paraneoplastic Sjogren’s syndrome in gastric cancer |
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In clinical practice, various masks of oncological diseases are often found. Some of them can manifest as a variety of syndromes or symptom complexes that resemble many non-oncologic diseases, including diffuse connective tissue diseases. In some cases, paraneoplastic syndrome facilitates diagnosing a malignant neoplasm in the early stages, but, unfortunately, can also mimic the tumor process by its more prominent manifestations, which lead to late establishment of the true cause of the disease, and therefore postpone specific treatment, creating significant clinical problems. Aim of the study was to reveal pathogenetic relationship between cancer and paraneoplastic syndrome on the example of our clinical observation. A clinical case of diagnosed paraneoplastic syndrome in the form of secondary Sjogren's syndrome, which developed long before the diagnosis of stomach cancer was made, as well as the results of clinical, instrumental, and laboratory examination of the patient, are presented. Questions of epidemiology, etiopathogenesis, and clinical picture of paraneoplastic syndrome are covered. The presented clinical case made it possible to outline the features of the course of paraneoplastic Sjogren's syndrome in gastric cancer and to identify a number of criteria for the diagnostic algorithm of this nosology. In particular, such criteria include general pathogenetic mechanisms, development only in malignant tumors, nonspecific clinical and laboratory manifestations, lack of parallelism with local symptoms of the tumor, the possibility of occurrence of paraneoplastic Sjogren's syndrome before development of local tumor symptoms and reappearance after its relapse. Oncologic diseases are characterized not only by specific symptoms characteristic for a certain organ damage (pain, bleeding, dysfunction, etc.), but also by a variety of nonspecific manifestations (fatigue, subfebrile temperature, weight loss, etc.) regardless of the nature, location and prevalence of the tumor process. |
| abstractGer |
In clinical practice, various masks of oncological diseases are often found. Some of them can manifest as a variety of syndromes or symptom complexes that resemble many non-oncologic diseases, including diffuse connective tissue diseases. In some cases, paraneoplastic syndrome facilitates diagnosing a malignant neoplasm in the early stages, but, unfortunately, can also mimic the tumor process by its more prominent manifestations, which lead to late establishment of the true cause of the disease, and therefore postpone specific treatment, creating significant clinical problems. Aim of the study was to reveal pathogenetic relationship between cancer and paraneoplastic syndrome on the example of our clinical observation. A clinical case of diagnosed paraneoplastic syndrome in the form of secondary Sjogren's syndrome, which developed long before the diagnosis of stomach cancer was made, as well as the results of clinical, instrumental, and laboratory examination of the patient, are presented. Questions of epidemiology, etiopathogenesis, and clinical picture of paraneoplastic syndrome are covered. The presented clinical case made it possible to outline the features of the course of paraneoplastic Sjogren's syndrome in gastric cancer and to identify a number of criteria for the diagnostic algorithm of this nosology. In particular, such criteria include general pathogenetic mechanisms, development only in malignant tumors, nonspecific clinical and laboratory manifestations, lack of parallelism with local symptoms of the tumor, the possibility of occurrence of paraneoplastic Sjogren's syndrome before development of local tumor symptoms and reappearance after its relapse. Oncologic diseases are characterized not only by specific symptoms characteristic for a certain organ damage (pain, bleeding, dysfunction, etc.), but also by a variety of nonspecific manifestations (fatigue, subfebrile temperature, weight loss, etc.) regardless of the nature, location and prevalence of the tumor process. |
| abstract_unstemmed |
In clinical practice, various masks of oncological diseases are often found. Some of them can manifest as a variety of syndromes or symptom complexes that resemble many non-oncologic diseases, including diffuse connective tissue diseases. In some cases, paraneoplastic syndrome facilitates diagnosing a malignant neoplasm in the early stages, but, unfortunately, can also mimic the tumor process by its more prominent manifestations, which lead to late establishment of the true cause of the disease, and therefore postpone specific treatment, creating significant clinical problems. Aim of the study was to reveal pathogenetic relationship between cancer and paraneoplastic syndrome on the example of our clinical observation. A clinical case of diagnosed paraneoplastic syndrome in the form of secondary Sjogren's syndrome, which developed long before the diagnosis of stomach cancer was made, as well as the results of clinical, instrumental, and laboratory examination of the patient, are presented. Questions of epidemiology, etiopathogenesis, and clinical picture of paraneoplastic syndrome are covered. The presented clinical case made it possible to outline the features of the course of paraneoplastic Sjogren's syndrome in gastric cancer and to identify a number of criteria for the diagnostic algorithm of this nosology. In particular, such criteria include general pathogenetic mechanisms, development only in malignant tumors, nonspecific clinical and laboratory manifestations, lack of parallelism with local symptoms of the tumor, the possibility of occurrence of paraneoplastic Sjogren's syndrome before development of local tumor symptoms and reappearance after its relapse. Oncologic diseases are characterized not only by specific symptoms characteristic for a certain organ damage (pain, bleeding, dysfunction, etc.), but also by a variety of nonspecific manifestations (fatigue, subfebrile temperature, weight loss, etc.) regardless of the nature, location and prevalence of the tumor process. |
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