Phytocosmetic Emulsion Containing Extract of <i<Morus nigra</i< L. (Moraceae): Development, Stability Study, Antioxidant and Antibacterial Activities

<i<Morus nigra</i< L. is a species popularly known in the Northeast of Brazil as “amora miúra”. This species is a source of flavonoids with antioxidant activity. Antioxidants play an important role in the preservation of cosmetic formulations, and they neutralize free radicals. The objec...
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Autor*in:	Rafaela Santos de Melo [verfasserIn] Silvio Alan Gonçalves Bomfim Reis [verfasserIn] Amanda Leite Guimarães [verfasserIn] Naiane Darklei dos Santos Silva [verfasserIn] Joao Miguel Rocha [verfasserIn] Noureddine El Aouad [verfasserIn] Jackson Roberto Guedes da Silva Almeida [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022

Schlagwörter:	black mulberry phytocosmetics plant extracts antioxidants antibacterial

Übergeordnetes Werk:	In: Cosmetics - MDPI AG, 2014, 9(2022), 2, p 39
Übergeordnetes Werk:	volume:9 ; year:2022 ; number:2, p 39

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/cosmetics9020039

Katalog-ID:	DOAJ032290268

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spelling	10.3390/cosmetics9020039 doi (DE-627)DOAJ032290268 (DE-599)DOAJb1d74f1405494b4aa68af7ae60e489a6 DE-627 ger DE-627 rakwb eng QD1-999 Rafaela Santos de Melo verfasserin aut Phytocosmetic Emulsion Containing Extract of <i<Morus nigra</i< L. (Moraceae): Development, Stability Study, Antioxidant and Antibacterial Activities 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <i<Morus nigra</i< L. is a species popularly known in the Northeast of Brazil as “amora miúra”. This species is a source of flavonoids with antioxidant activity. Antioxidants play an important role in the preservation of cosmetic formulations, and they neutralize free radicals. The objective of this study was to develop a topical emulsion containing leaf extract of <i<Morus nigra</i< L., as well as to evaluate the stability, antioxidant and antibacterial activities of the formulations. A crude hydroalcoholic (70%) extract of <i<M. nigra</i< leaves (MnCE) was submitted to high-performance liquid chromatography with diode-array detection (HPLC–DAD) analysis and incorporated into an anionic base emulsion. Antioxidant activity was evaluated according to the DPPH (2,2-diphenyl-1-picrylhydrazyl) method, and the stability of the formulation was assessed for 90 days, submitting the emulsion to storage at 4, 20, and 37 °C. Microdilution techniques evaluated the antibacterial activity and a challenge test assessed the microbiological stability. Analysis by HPLC–DAD identified the flavonoids rutin and isoquercetin in the <i<M. nigra</i< extract. The emulsion and plant extract presented antioxidant activity, and the stability of the emulsion was preserved in terms of pH value and viscosity—which did not show significant changes, except for the spreadability, which was affected by the temperature. The antioxidant activity did not change significantly, except for the sample under 4 °C, which showed a considerable decrease in activity. The crude hydroalcoholic extract and formulation showed antimicrobial activity and the emulsion was considered stable in terms of organoleptic, physicochemical, and microbiological properties. <i<Morus nigra</i< black mulberry phytocosmetics plant extracts antioxidants antibacterial Chemistry Silvio Alan Gonçalves Bomfim Reis verfasserin aut Amanda Leite Guimarães verfasserin aut Naiane Darklei dos Santos Silva verfasserin aut Joao Miguel Rocha verfasserin aut Noureddine El Aouad verfasserin aut Jackson Roberto Guedes da Silva Almeida verfasserin aut In Cosmetics MDPI AG, 2014 9(2022), 2, p 39 (DE-627)750370491 (DE-600)2720868-0 20799284 nnns volume:9 year:2022 number:2, p 39 https://doi.org/10.3390/cosmetics9020039 kostenfrei https://doaj.org/article/b1d74f1405494b4aa68af7ae60e489a6 kostenfrei https://www.mdpi.com/2079-9284/9/2/39 kostenfrei https://doaj.org/toc/2079-9284 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2022 2, p 39
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allfieldsSound	10.3390/cosmetics9020039 doi (DE-627)DOAJ032290268 (DE-599)DOAJb1d74f1405494b4aa68af7ae60e489a6 DE-627 ger DE-627 rakwb eng QD1-999 Rafaela Santos de Melo verfasserin aut Phytocosmetic Emulsion Containing Extract of <i<Morus nigra</i< L. (Moraceae): Development, Stability Study, Antioxidant and Antibacterial Activities 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <i<Morus nigra</i< L. is a species popularly known in the Northeast of Brazil as “amora miúra”. This species is a source of flavonoids with antioxidant activity. Antioxidants play an important role in the preservation of cosmetic formulations, and they neutralize free radicals. The objective of this study was to develop a topical emulsion containing leaf extract of <i<Morus nigra</i< L., as well as to evaluate the stability, antioxidant and antibacterial activities of the formulations. A crude hydroalcoholic (70%) extract of <i<M. nigra</i< leaves (MnCE) was submitted to high-performance liquid chromatography with diode-array detection (HPLC–DAD) analysis and incorporated into an anionic base emulsion. Antioxidant activity was evaluated according to the DPPH (2,2-diphenyl-1-picrylhydrazyl) method, and the stability of the formulation was assessed for 90 days, submitting the emulsion to storage at 4, 20, and 37 °C. Microdilution techniques evaluated the antibacterial activity and a challenge test assessed the microbiological stability. Analysis by HPLC–DAD identified the flavonoids rutin and isoquercetin in the <i<M. nigra</i< extract. The emulsion and plant extract presented antioxidant activity, and the stability of the emulsion was preserved in terms of pH value and viscosity—which did not show significant changes, except for the spreadability, which was affected by the temperature. The antioxidant activity did not change significantly, except for the sample under 4 °C, which showed a considerable decrease in activity. The crude hydroalcoholic extract and formulation showed antimicrobial activity and the emulsion was considered stable in terms of organoleptic, physicochemical, and microbiological properties. <i<Morus nigra</i< black mulberry phytocosmetics plant extracts antioxidants antibacterial Chemistry Silvio Alan Gonçalves Bomfim Reis verfasserin aut Amanda Leite Guimarães verfasserin aut Naiane Darklei dos Santos Silva verfasserin aut Joao Miguel Rocha verfasserin aut Noureddine El Aouad verfasserin aut Jackson Roberto Guedes da Silva Almeida verfasserin aut In Cosmetics MDPI AG, 2014 9(2022), 2, p 39 (DE-627)750370491 (DE-600)2720868-0 20799284 nnns volume:9 year:2022 number:2, p 39 https://doi.org/10.3390/cosmetics9020039 kostenfrei https://doaj.org/article/b1d74f1405494b4aa68af7ae60e489a6 kostenfrei https://www.mdpi.com/2079-9284/9/2/39 kostenfrei https://doaj.org/toc/2079-9284 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2022 2, p 39
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source	In Cosmetics 9(2022), 2, p 39 volume:9 year:2022 number:2, p 39
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author	Rafaela Santos de Melo
spellingShingle	Rafaela Santos de Melo misc QD1-999 misc <i<Morus nigra</i< misc black mulberry misc phytocosmetics misc plant extracts misc antioxidants misc antibacterial misc Chemistry Phytocosmetic Emulsion Containing Extract of <i<Morus nigra</i< L. (Moraceae): Development, Stability Study, Antioxidant and Antibacterial Activities
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topic_title	QD1-999 Phytocosmetic Emulsion Containing Extract of <i<Morus nigra</i< L. (Moraceae): Development, Stability Study, Antioxidant and Antibacterial Activities <i<Morus nigra</i< black mulberry phytocosmetics plant extracts antioxidants antibacterial
topic	misc QD1-999 misc <i<Morus nigra</i< misc black mulberry misc phytocosmetics misc plant extracts misc antioxidants misc antibacterial misc Chemistry
topic_unstemmed	misc QD1-999 misc <i<Morus nigra</i< misc black mulberry misc phytocosmetics misc plant extracts misc antioxidants misc antibacterial misc Chemistry
topic_browse	misc QD1-999 misc <i<Morus nigra</i< misc black mulberry misc phytocosmetics misc plant extracts misc antioxidants misc antibacterial misc Chemistry
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title	Phytocosmetic Emulsion Containing Extract of <i<Morus nigra</i< L. (Moraceae): Development, Stability Study, Antioxidant and Antibacterial Activities
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title_full	Phytocosmetic Emulsion Containing Extract of <i<Morus nigra</i< L. (Moraceae): Development, Stability Study, Antioxidant and Antibacterial Activities
author_sort	Rafaela Santos de Melo
journal	Cosmetics
journalStr	Cosmetics
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author_browse	Rafaela Santos de Melo Silvio Alan Gonçalves Bomfim Reis Amanda Leite Guimarães Naiane Darklei dos Santos Silva Joao Miguel Rocha Noureddine El Aouad Jackson Roberto Guedes da Silva Almeida
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author-letter	Rafaela Santos de Melo
doi_str_mv	10.3390/cosmetics9020039
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title_sort	phytocosmetic emulsion containing extract of <i<morus nigra</i< l. (moraceae): development, stability study, antioxidant and antibacterial activities
callnumber	QD1-999
title_auth	Phytocosmetic Emulsion Containing Extract of <i<Morus nigra</i< L. (Moraceae): Development, Stability Study, Antioxidant and Antibacterial Activities
abstract	<i<Morus nigra</i< L. is a species popularly known in the Northeast of Brazil as “amora miúra”. This species is a source of flavonoids with antioxidant activity. Antioxidants play an important role in the preservation of cosmetic formulations, and they neutralize free radicals. The objective of this study was to develop a topical emulsion containing leaf extract of <i<Morus nigra</i< L., as well as to evaluate the stability, antioxidant and antibacterial activities of the formulations. A crude hydroalcoholic (70%) extract of <i<M. nigra</i< leaves (MnCE) was submitted to high-performance liquid chromatography with diode-array detection (HPLC–DAD) analysis and incorporated into an anionic base emulsion. Antioxidant activity was evaluated according to the DPPH (2,2-diphenyl-1-picrylhydrazyl) method, and the stability of the formulation was assessed for 90 days, submitting the emulsion to storage at 4, 20, and 37 °C. Microdilution techniques evaluated the antibacterial activity and a challenge test assessed the microbiological stability. Analysis by HPLC–DAD identified the flavonoids rutin and isoquercetin in the <i<M. nigra</i< extract. The emulsion and plant extract presented antioxidant activity, and the stability of the emulsion was preserved in terms of pH value and viscosity—which did not show significant changes, except for the spreadability, which was affected by the temperature. The antioxidant activity did not change significantly, except for the sample under 4 °C, which showed a considerable decrease in activity. The crude hydroalcoholic extract and formulation showed antimicrobial activity and the emulsion was considered stable in terms of organoleptic, physicochemical, and microbiological properties.
abstractGer	<i<Morus nigra</i< L. is a species popularly known in the Northeast of Brazil as “amora miúra”. This species is a source of flavonoids with antioxidant activity. Antioxidants play an important role in the preservation of cosmetic formulations, and they neutralize free radicals. The objective of this study was to develop a topical emulsion containing leaf extract of <i<Morus nigra</i< L., as well as to evaluate the stability, antioxidant and antibacterial activities of the formulations. A crude hydroalcoholic (70%) extract of <i<M. nigra</i< leaves (MnCE) was submitted to high-performance liquid chromatography with diode-array detection (HPLC–DAD) analysis and incorporated into an anionic base emulsion. Antioxidant activity was evaluated according to the DPPH (2,2-diphenyl-1-picrylhydrazyl) method, and the stability of the formulation was assessed for 90 days, submitting the emulsion to storage at 4, 20, and 37 °C. Microdilution techniques evaluated the antibacterial activity and a challenge test assessed the microbiological stability. Analysis by HPLC–DAD identified the flavonoids rutin and isoquercetin in the <i<M. nigra</i< extract. The emulsion and plant extract presented antioxidant activity, and the stability of the emulsion was preserved in terms of pH value and viscosity—which did not show significant changes, except for the spreadability, which was affected by the temperature. The antioxidant activity did not change significantly, except for the sample under 4 °C, which showed a considerable decrease in activity. The crude hydroalcoholic extract and formulation showed antimicrobial activity and the emulsion was considered stable in terms of organoleptic, physicochemical, and microbiological properties.
abstract_unstemmed	<i<Morus nigra</i< L. is a species popularly known in the Northeast of Brazil as “amora miúra”. This species is a source of flavonoids with antioxidant activity. Antioxidants play an important role in the preservation of cosmetic formulations, and they neutralize free radicals. The objective of this study was to develop a topical emulsion containing leaf extract of <i<Morus nigra</i< L., as well as to evaluate the stability, antioxidant and antibacterial activities of the formulations. A crude hydroalcoholic (70%) extract of <i<M. nigra</i< leaves (MnCE) was submitted to high-performance liquid chromatography with diode-array detection (HPLC–DAD) analysis and incorporated into an anionic base emulsion. Antioxidant activity was evaluated according to the DPPH (2,2-diphenyl-1-picrylhydrazyl) method, and the stability of the formulation was assessed for 90 days, submitting the emulsion to storage at 4, 20, and 37 °C. Microdilution techniques evaluated the antibacterial activity and a challenge test assessed the microbiological stability. Analysis by HPLC–DAD identified the flavonoids rutin and isoquercetin in the <i<M. nigra</i< extract. The emulsion and plant extract presented antioxidant activity, and the stability of the emulsion was preserved in terms of pH value and viscosity—which did not show significant changes, except for the spreadability, which was affected by the temperature. The antioxidant activity did not change significantly, except for the sample under 4 °C, which showed a considerable decrease in activity. The crude hydroalcoholic extract and formulation showed antimicrobial activity and the emulsion was considered stable in terms of organoleptic, physicochemical, and microbiological properties.
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title_short	Phytocosmetic Emulsion Containing Extract of <i<Morus nigra</i< L. (Moraceae): Development, Stability Study, Antioxidant and Antibacterial Activities
url	https://doi.org/10.3390/cosmetics9020039 https://doaj.org/article/b1d74f1405494b4aa68af7ae60e489a6 https://www.mdpi.com/2079-9284/9/2/39 https://doaj.org/toc/2079-9284
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