Unsupervised Exercise and Mobility Loss in Peripheral Artery Disease: A Randomized Controlled Trial
Background Few medical therapies improve lower extremity functioning in people with lower extremity peripheral artery disease (PAD). Among people with PAD, we studied whether a group‐mediated cognitive behavioral intervention promoting home‐based unsupervised exercise prevented mobility loss and imp...
Ausführliche Beschreibung
Autor*in: |
Mary M. McDermott [verfasserIn] Jack M. Guralnik [verfasserIn] Michael H. Criqui [verfasserIn] Luigi Ferrucci [verfasserIn] Kiang Liu [verfasserIn] Bonnie Spring [verfasserIn] Lu Tian [verfasserIn] Kathryn Domanchuk [verfasserIn] Melina Kibbe [verfasserIn] Lihui Zhao [verfasserIn] Donald Lloyd Jones [verfasserIn] Yihua Liao [verfasserIn] Ying Gao [verfasserIn] W. Jack Rejeski [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2015 |
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In: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease - Wiley, 2012, 4(2015), 5, Seite n/a-n/a |
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Übergeordnetes Werk: |
volume:4 ; year:2015 ; number:5 ; pages:n/a-n/a |
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DOI / URN: |
10.1161/JAHA.114.001659 |
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Katalog-ID: |
DOAJ032510721 |
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520 | |a Background Few medical therapies improve lower extremity functioning in people with lower extremity peripheral artery disease (PAD). Among people with PAD, we studied whether a group‐mediated cognitive behavioral intervention promoting home‐based unsupervised exercise prevented mobility loss and improved functional performance compared to control. Methods and Results One hundred ninety‐four PAD participants were randomized. During months 1 to 6, the intervention group met weekly with other PAD participants and a facilitator. Group support and self‐regulatory skills were used to help participants adhere to walking exercise. Ninety‐percent of exercise was conducted at or near home. The control group attended weekly lectures. During months 6 to 12, each group received telephone contact only. Primary outcomes have been reported. Here we compare changes in exploratory outcomes of mobility loss (the inability to climb a flight of stairs or walk one‐quarter mile without assistance), walking velocity, and the Short Physical Performance Battery. Compared to controls, fewer participants randomized to the intervention experienced mobility loss at 6‐month follow‐up: 6.3% versus 26.5%, P=0.002, odds ratio=0.19 (95% CI=0.06 to 0.58) and at 12‐month follow‐up: 5.2% versus 18.5%, P=0.029, odds ratio=0.24 (95% CI=0.06 to 0.97). The intervention improved fast‐paced 4‐m walking velocity at 6‐month follow‐up (P=0.005) and the Short Physical Performance Battery at 12‐month follow‐up (P=0.027), compared to controls. Conclusions In exploratory analyses, a group‐mediated cognitive behavioral intervention promoting unsupervised walking exercise prevented mobility loss and improved functioning at 6‐ and 12‐month follow‐up in PAD patients. Clinical Trial Registration URL: http://clinicaltrials.gov. Unique identifier: NCT00693940. | ||
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700 | 0 | |a Jack M. Guralnik |e verfasserin |4 aut | |
700 | 0 | |a Michael H. Criqui |e verfasserin |4 aut | |
700 | 0 | |a Luigi Ferrucci |e verfasserin |4 aut | |
700 | 0 | |a Kiang Liu |e verfasserin |4 aut | |
700 | 0 | |a Bonnie Spring |e verfasserin |4 aut | |
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700 | 0 | |a Donald Lloyd Jones |e verfasserin |4 aut | |
700 | 0 | |a Yihua Liao |e verfasserin |4 aut | |
700 | 0 | |a Ying Gao |e verfasserin |4 aut | |
700 | 0 | |a W. Jack Rejeski |e verfasserin |4 aut | |
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10.1161/JAHA.114.001659 doi (DE-627)DOAJ032510721 (DE-599)DOAJec2ef63958634b82b57a16c582cd2058 DE-627 ger DE-627 rakwb eng RC666-701 Mary M. McDermott verfasserin aut Unsupervised Exercise and Mobility Loss in Peripheral Artery Disease: A Randomized Controlled Trial 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Few medical therapies improve lower extremity functioning in people with lower extremity peripheral artery disease (PAD). Among people with PAD, we studied whether a group‐mediated cognitive behavioral intervention promoting home‐based unsupervised exercise prevented mobility loss and improved functional performance compared to control. Methods and Results One hundred ninety‐four PAD participants were randomized. During months 1 to 6, the intervention group met weekly with other PAD participants and a facilitator. Group support and self‐regulatory skills were used to help participants adhere to walking exercise. Ninety‐percent of exercise was conducted at or near home. The control group attended weekly lectures. During months 6 to 12, each group received telephone contact only. Primary outcomes have been reported. Here we compare changes in exploratory outcomes of mobility loss (the inability to climb a flight of stairs or walk one‐quarter mile without assistance), walking velocity, and the Short Physical Performance Battery. Compared to controls, fewer participants randomized to the intervention experienced mobility loss at 6‐month follow‐up: 6.3% versus 26.5%, P=0.002, odds ratio=0.19 (95% CI=0.06 to 0.58) and at 12‐month follow‐up: 5.2% versus 18.5%, P=0.029, odds ratio=0.24 (95% CI=0.06 to 0.97). The intervention improved fast‐paced 4‐m walking velocity at 6‐month follow‐up (P=0.005) and the Short Physical Performance Battery at 12‐month follow‐up (P=0.027), compared to controls. Conclusions In exploratory analyses, a group‐mediated cognitive behavioral intervention promoting unsupervised walking exercise prevented mobility loss and improved functioning at 6‐ and 12‐month follow‐up in PAD patients. Clinical Trial Registration URL: http://clinicaltrials.gov. Unique identifier: NCT00693940. exercise mobility peripheral artery disease randomized controlled trial Diseases of the circulatory (Cardiovascular) system Jack M. Guralnik verfasserin aut Michael H. Criqui verfasserin aut Luigi Ferrucci verfasserin aut Kiang Liu verfasserin aut Bonnie Spring verfasserin aut Lu Tian verfasserin aut Kathryn Domanchuk verfasserin aut Melina Kibbe verfasserin aut Lihui Zhao verfasserin aut Donald Lloyd Jones verfasserin aut Yihua Liao verfasserin aut Ying Gao verfasserin aut W. Jack Rejeski verfasserin aut In Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease Wiley, 2012 4(2015), 5, Seite n/a-n/a (DE-627)688605427 (DE-600)2653953-6 20479980 nnns volume:4 year:2015 number:5 pages:n/a-n/a https://doi.org/10.1161/JAHA.114.001659 kostenfrei https://doaj.org/article/ec2ef63958634b82b57a16c582cd2058 kostenfrei https://doi.org/10.1161/JAHA.114.001659 kostenfrei https://doaj.org/toc/2047-9980 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2015 5 n/a-n/a |
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10.1161/JAHA.114.001659 doi (DE-627)DOAJ032510721 (DE-599)DOAJec2ef63958634b82b57a16c582cd2058 DE-627 ger DE-627 rakwb eng RC666-701 Mary M. McDermott verfasserin aut Unsupervised Exercise and Mobility Loss in Peripheral Artery Disease: A Randomized Controlled Trial 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Few medical therapies improve lower extremity functioning in people with lower extremity peripheral artery disease (PAD). Among people with PAD, we studied whether a group‐mediated cognitive behavioral intervention promoting home‐based unsupervised exercise prevented mobility loss and improved functional performance compared to control. Methods and Results One hundred ninety‐four PAD participants were randomized. During months 1 to 6, the intervention group met weekly with other PAD participants and a facilitator. Group support and self‐regulatory skills were used to help participants adhere to walking exercise. Ninety‐percent of exercise was conducted at or near home. The control group attended weekly lectures. During months 6 to 12, each group received telephone contact only. Primary outcomes have been reported. Here we compare changes in exploratory outcomes of mobility loss (the inability to climb a flight of stairs or walk one‐quarter mile without assistance), walking velocity, and the Short Physical Performance Battery. Compared to controls, fewer participants randomized to the intervention experienced mobility loss at 6‐month follow‐up: 6.3% versus 26.5%, P=0.002, odds ratio=0.19 (95% CI=0.06 to 0.58) and at 12‐month follow‐up: 5.2% versus 18.5%, P=0.029, odds ratio=0.24 (95% CI=0.06 to 0.97). The intervention improved fast‐paced 4‐m walking velocity at 6‐month follow‐up (P=0.005) and the Short Physical Performance Battery at 12‐month follow‐up (P=0.027), compared to controls. Conclusions In exploratory analyses, a group‐mediated cognitive behavioral intervention promoting unsupervised walking exercise prevented mobility loss and improved functioning at 6‐ and 12‐month follow‐up in PAD patients. Clinical Trial Registration URL: http://clinicaltrials.gov. Unique identifier: NCT00693940. exercise mobility peripheral artery disease randomized controlled trial Diseases of the circulatory (Cardiovascular) system Jack M. Guralnik verfasserin aut Michael H. Criqui verfasserin aut Luigi Ferrucci verfasserin aut Kiang Liu verfasserin aut Bonnie Spring verfasserin aut Lu Tian verfasserin aut Kathryn Domanchuk verfasserin aut Melina Kibbe verfasserin aut Lihui Zhao verfasserin aut Donald Lloyd Jones verfasserin aut Yihua Liao verfasserin aut Ying Gao verfasserin aut W. Jack Rejeski verfasserin aut In Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease Wiley, 2012 4(2015), 5, Seite n/a-n/a (DE-627)688605427 (DE-600)2653953-6 20479980 nnns volume:4 year:2015 number:5 pages:n/a-n/a https://doi.org/10.1161/JAHA.114.001659 kostenfrei https://doaj.org/article/ec2ef63958634b82b57a16c582cd2058 kostenfrei https://doi.org/10.1161/JAHA.114.001659 kostenfrei https://doaj.org/toc/2047-9980 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2015 5 n/a-n/a |
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10.1161/JAHA.114.001659 doi (DE-627)DOAJ032510721 (DE-599)DOAJec2ef63958634b82b57a16c582cd2058 DE-627 ger DE-627 rakwb eng RC666-701 Mary M. McDermott verfasserin aut Unsupervised Exercise and Mobility Loss in Peripheral Artery Disease: A Randomized Controlled Trial 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Few medical therapies improve lower extremity functioning in people with lower extremity peripheral artery disease (PAD). Among people with PAD, we studied whether a group‐mediated cognitive behavioral intervention promoting home‐based unsupervised exercise prevented mobility loss and improved functional performance compared to control. Methods and Results One hundred ninety‐four PAD participants were randomized. During months 1 to 6, the intervention group met weekly with other PAD participants and a facilitator. Group support and self‐regulatory skills were used to help participants adhere to walking exercise. Ninety‐percent of exercise was conducted at or near home. The control group attended weekly lectures. During months 6 to 12, each group received telephone contact only. Primary outcomes have been reported. Here we compare changes in exploratory outcomes of mobility loss (the inability to climb a flight of stairs or walk one‐quarter mile without assistance), walking velocity, and the Short Physical Performance Battery. Compared to controls, fewer participants randomized to the intervention experienced mobility loss at 6‐month follow‐up: 6.3% versus 26.5%, P=0.002, odds ratio=0.19 (95% CI=0.06 to 0.58) and at 12‐month follow‐up: 5.2% versus 18.5%, P=0.029, odds ratio=0.24 (95% CI=0.06 to 0.97). The intervention improved fast‐paced 4‐m walking velocity at 6‐month follow‐up (P=0.005) and the Short Physical Performance Battery at 12‐month follow‐up (P=0.027), compared to controls. Conclusions In exploratory analyses, a group‐mediated cognitive behavioral intervention promoting unsupervised walking exercise prevented mobility loss and improved functioning at 6‐ and 12‐month follow‐up in PAD patients. Clinical Trial Registration URL: http://clinicaltrials.gov. Unique identifier: NCT00693940. exercise mobility peripheral artery disease randomized controlled trial Diseases of the circulatory (Cardiovascular) system Jack M. Guralnik verfasserin aut Michael H. Criqui verfasserin aut Luigi Ferrucci verfasserin aut Kiang Liu verfasserin aut Bonnie Spring verfasserin aut Lu Tian verfasserin aut Kathryn Domanchuk verfasserin aut Melina Kibbe verfasserin aut Lihui Zhao verfasserin aut Donald Lloyd Jones verfasserin aut Yihua Liao verfasserin aut Ying Gao verfasserin aut W. Jack Rejeski verfasserin aut In Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease Wiley, 2012 4(2015), 5, Seite n/a-n/a (DE-627)688605427 (DE-600)2653953-6 20479980 nnns volume:4 year:2015 number:5 pages:n/a-n/a https://doi.org/10.1161/JAHA.114.001659 kostenfrei https://doaj.org/article/ec2ef63958634b82b57a16c582cd2058 kostenfrei https://doi.org/10.1161/JAHA.114.001659 kostenfrei https://doaj.org/toc/2047-9980 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2015 5 n/a-n/a |
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10.1161/JAHA.114.001659 doi (DE-627)DOAJ032510721 (DE-599)DOAJec2ef63958634b82b57a16c582cd2058 DE-627 ger DE-627 rakwb eng RC666-701 Mary M. McDermott verfasserin aut Unsupervised Exercise and Mobility Loss in Peripheral Artery Disease: A Randomized Controlled Trial 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Few medical therapies improve lower extremity functioning in people with lower extremity peripheral artery disease (PAD). Among people with PAD, we studied whether a group‐mediated cognitive behavioral intervention promoting home‐based unsupervised exercise prevented mobility loss and improved functional performance compared to control. Methods and Results One hundred ninety‐four PAD participants were randomized. During months 1 to 6, the intervention group met weekly with other PAD participants and a facilitator. Group support and self‐regulatory skills were used to help participants adhere to walking exercise. Ninety‐percent of exercise was conducted at or near home. The control group attended weekly lectures. During months 6 to 12, each group received telephone contact only. Primary outcomes have been reported. Here we compare changes in exploratory outcomes of mobility loss (the inability to climb a flight of stairs or walk one‐quarter mile without assistance), walking velocity, and the Short Physical Performance Battery. Compared to controls, fewer participants randomized to the intervention experienced mobility loss at 6‐month follow‐up: 6.3% versus 26.5%, P=0.002, odds ratio=0.19 (95% CI=0.06 to 0.58) and at 12‐month follow‐up: 5.2% versus 18.5%, P=0.029, odds ratio=0.24 (95% CI=0.06 to 0.97). The intervention improved fast‐paced 4‐m walking velocity at 6‐month follow‐up (P=0.005) and the Short Physical Performance Battery at 12‐month follow‐up (P=0.027), compared to controls. Conclusions In exploratory analyses, a group‐mediated cognitive behavioral intervention promoting unsupervised walking exercise prevented mobility loss and improved functioning at 6‐ and 12‐month follow‐up in PAD patients. Clinical Trial Registration URL: http://clinicaltrials.gov. Unique identifier: NCT00693940. exercise mobility peripheral artery disease randomized controlled trial Diseases of the circulatory (Cardiovascular) system Jack M. Guralnik verfasserin aut Michael H. Criqui verfasserin aut Luigi Ferrucci verfasserin aut Kiang Liu verfasserin aut Bonnie Spring verfasserin aut Lu Tian verfasserin aut Kathryn Domanchuk verfasserin aut Melina Kibbe verfasserin aut Lihui Zhao verfasserin aut Donald Lloyd Jones verfasserin aut Yihua Liao verfasserin aut Ying Gao verfasserin aut W. Jack Rejeski verfasserin aut In Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease Wiley, 2012 4(2015), 5, Seite n/a-n/a (DE-627)688605427 (DE-600)2653953-6 20479980 nnns volume:4 year:2015 number:5 pages:n/a-n/a https://doi.org/10.1161/JAHA.114.001659 kostenfrei https://doaj.org/article/ec2ef63958634b82b57a16c582cd2058 kostenfrei https://doi.org/10.1161/JAHA.114.001659 kostenfrei https://doaj.org/toc/2047-9980 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2015 5 n/a-n/a |
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10.1161/JAHA.114.001659 doi (DE-627)DOAJ032510721 (DE-599)DOAJec2ef63958634b82b57a16c582cd2058 DE-627 ger DE-627 rakwb eng RC666-701 Mary M. McDermott verfasserin aut Unsupervised Exercise and Mobility Loss in Peripheral Artery Disease: A Randomized Controlled Trial 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background Few medical therapies improve lower extremity functioning in people with lower extremity peripheral artery disease (PAD). Among people with PAD, we studied whether a group‐mediated cognitive behavioral intervention promoting home‐based unsupervised exercise prevented mobility loss and improved functional performance compared to control. Methods and Results One hundred ninety‐four PAD participants were randomized. During months 1 to 6, the intervention group met weekly with other PAD participants and a facilitator. Group support and self‐regulatory skills were used to help participants adhere to walking exercise. Ninety‐percent of exercise was conducted at or near home. The control group attended weekly lectures. During months 6 to 12, each group received telephone contact only. Primary outcomes have been reported. Here we compare changes in exploratory outcomes of mobility loss (the inability to climb a flight of stairs or walk one‐quarter mile without assistance), walking velocity, and the Short Physical Performance Battery. Compared to controls, fewer participants randomized to the intervention experienced mobility loss at 6‐month follow‐up: 6.3% versus 26.5%, P=0.002, odds ratio=0.19 (95% CI=0.06 to 0.58) and at 12‐month follow‐up: 5.2% versus 18.5%, P=0.029, odds ratio=0.24 (95% CI=0.06 to 0.97). The intervention improved fast‐paced 4‐m walking velocity at 6‐month follow‐up (P=0.005) and the Short Physical Performance Battery at 12‐month follow‐up (P=0.027), compared to controls. Conclusions In exploratory analyses, a group‐mediated cognitive behavioral intervention promoting unsupervised walking exercise prevented mobility loss and improved functioning at 6‐ and 12‐month follow‐up in PAD patients. Clinical Trial Registration URL: http://clinicaltrials.gov. Unique identifier: NCT00693940. exercise mobility peripheral artery disease randomized controlled trial Diseases of the circulatory (Cardiovascular) system Jack M. Guralnik verfasserin aut Michael H. Criqui verfasserin aut Luigi Ferrucci verfasserin aut Kiang Liu verfasserin aut Bonnie Spring verfasserin aut Lu Tian verfasserin aut Kathryn Domanchuk verfasserin aut Melina Kibbe verfasserin aut Lihui Zhao verfasserin aut Donald Lloyd Jones verfasserin aut Yihua Liao verfasserin aut Ying Gao verfasserin aut W. Jack Rejeski verfasserin aut In Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease Wiley, 2012 4(2015), 5, Seite n/a-n/a (DE-627)688605427 (DE-600)2653953-6 20479980 nnns volume:4 year:2015 number:5 pages:n/a-n/a https://doi.org/10.1161/JAHA.114.001659 kostenfrei https://doaj.org/article/ec2ef63958634b82b57a16c582cd2058 kostenfrei https://doi.org/10.1161/JAHA.114.001659 kostenfrei https://doaj.org/toc/2047-9980 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2015 5 n/a-n/a |
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Mary M. McDermott @@aut@@ Jack M. Guralnik @@aut@@ Michael H. Criqui @@aut@@ Luigi Ferrucci @@aut@@ Kiang Liu @@aut@@ Bonnie Spring @@aut@@ Lu Tian @@aut@@ Kathryn Domanchuk @@aut@@ Melina Kibbe @@aut@@ Lihui Zhao @@aut@@ Donald Lloyd Jones @@aut@@ Yihua Liao @@aut@@ Ying Gao @@aut@@ W. Jack Rejeski @@aut@@ |
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McDermott</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Unsupervised Exercise and Mobility Loss in Peripheral Artery Disease: A Randomized Controlled Trial</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2015</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background Few medical therapies improve lower extremity functioning in people with lower extremity peripheral artery disease (PAD). Among people with PAD, we studied whether a group‐mediated cognitive behavioral intervention promoting home‐based unsupervised exercise prevented mobility loss and improved functional performance compared to control. Methods and Results One hundred ninety‐four PAD participants were randomized. During months 1 to 6, the intervention group met weekly with other PAD participants and a facilitator. Group support and self‐regulatory skills were used to help participants adhere to walking exercise. Ninety‐percent of exercise was conducted at or near home. The control group attended weekly lectures. During months 6 to 12, each group received telephone contact only. Primary outcomes have been reported. Here we compare changes in exploratory outcomes of mobility loss (the inability to climb a flight of stairs or walk one‐quarter mile without assistance), walking velocity, and the Short Physical Performance Battery. Compared to controls, fewer participants randomized to the intervention experienced mobility loss at 6‐month follow‐up: 6.3% versus 26.5%, P=0.002, odds ratio=0.19 (95% CI=0.06 to 0.58) and at 12‐month follow‐up: 5.2% versus 18.5%, P=0.029, odds ratio=0.24 (95% CI=0.06 to 0.97). The intervention improved fast‐paced 4‐m walking velocity at 6‐month follow‐up (P=0.005) and the Short Physical Performance Battery at 12‐month follow‐up (P=0.027), compared to controls. Conclusions In exploratory analyses, a group‐mediated cognitive behavioral intervention promoting unsupervised walking exercise prevented mobility loss and improved functioning at 6‐ and 12‐month follow‐up in PAD patients. Clinical Trial Registration URL: http://clinicaltrials.gov. 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Mary M. McDermott |
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Unsupervised Exercise and Mobility Loss in Peripheral Artery Disease: A Randomized Controlled Trial |
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Unsupervised Exercise and Mobility Loss in Peripheral Artery Disease: A Randomized Controlled Trial |
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Mary M. McDermott Jack M. Guralnik Michael H. Criqui Luigi Ferrucci Kiang Liu Bonnie Spring Lu Tian Kathryn Domanchuk Melina Kibbe Lihui Zhao Donald Lloyd Jones Yihua Liao Ying Gao W. Jack Rejeski |
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unsupervised exercise and mobility loss in peripheral artery disease: a randomized controlled trial |
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Unsupervised Exercise and Mobility Loss in Peripheral Artery Disease: A Randomized Controlled Trial |
abstract |
Background Few medical therapies improve lower extremity functioning in people with lower extremity peripheral artery disease (PAD). Among people with PAD, we studied whether a group‐mediated cognitive behavioral intervention promoting home‐based unsupervised exercise prevented mobility loss and improved functional performance compared to control. Methods and Results One hundred ninety‐four PAD participants were randomized. During months 1 to 6, the intervention group met weekly with other PAD participants and a facilitator. Group support and self‐regulatory skills were used to help participants adhere to walking exercise. Ninety‐percent of exercise was conducted at or near home. The control group attended weekly lectures. During months 6 to 12, each group received telephone contact only. Primary outcomes have been reported. Here we compare changes in exploratory outcomes of mobility loss (the inability to climb a flight of stairs or walk one‐quarter mile without assistance), walking velocity, and the Short Physical Performance Battery. Compared to controls, fewer participants randomized to the intervention experienced mobility loss at 6‐month follow‐up: 6.3% versus 26.5%, P=0.002, odds ratio=0.19 (95% CI=0.06 to 0.58) and at 12‐month follow‐up: 5.2% versus 18.5%, P=0.029, odds ratio=0.24 (95% CI=0.06 to 0.97). The intervention improved fast‐paced 4‐m walking velocity at 6‐month follow‐up (P=0.005) and the Short Physical Performance Battery at 12‐month follow‐up (P=0.027), compared to controls. Conclusions In exploratory analyses, a group‐mediated cognitive behavioral intervention promoting unsupervised walking exercise prevented mobility loss and improved functioning at 6‐ and 12‐month follow‐up in PAD patients. Clinical Trial Registration URL: http://clinicaltrials.gov. Unique identifier: NCT00693940. |
abstractGer |
Background Few medical therapies improve lower extremity functioning in people with lower extremity peripheral artery disease (PAD). Among people with PAD, we studied whether a group‐mediated cognitive behavioral intervention promoting home‐based unsupervised exercise prevented mobility loss and improved functional performance compared to control. Methods and Results One hundred ninety‐four PAD participants were randomized. During months 1 to 6, the intervention group met weekly with other PAD participants and a facilitator. Group support and self‐regulatory skills were used to help participants adhere to walking exercise. Ninety‐percent of exercise was conducted at or near home. The control group attended weekly lectures. During months 6 to 12, each group received telephone contact only. Primary outcomes have been reported. Here we compare changes in exploratory outcomes of mobility loss (the inability to climb a flight of stairs or walk one‐quarter mile without assistance), walking velocity, and the Short Physical Performance Battery. Compared to controls, fewer participants randomized to the intervention experienced mobility loss at 6‐month follow‐up: 6.3% versus 26.5%, P=0.002, odds ratio=0.19 (95% CI=0.06 to 0.58) and at 12‐month follow‐up: 5.2% versus 18.5%, P=0.029, odds ratio=0.24 (95% CI=0.06 to 0.97). The intervention improved fast‐paced 4‐m walking velocity at 6‐month follow‐up (P=0.005) and the Short Physical Performance Battery at 12‐month follow‐up (P=0.027), compared to controls. Conclusions In exploratory analyses, a group‐mediated cognitive behavioral intervention promoting unsupervised walking exercise prevented mobility loss and improved functioning at 6‐ and 12‐month follow‐up in PAD patients. Clinical Trial Registration URL: http://clinicaltrials.gov. Unique identifier: NCT00693940. |
abstract_unstemmed |
Background Few medical therapies improve lower extremity functioning in people with lower extremity peripheral artery disease (PAD). Among people with PAD, we studied whether a group‐mediated cognitive behavioral intervention promoting home‐based unsupervised exercise prevented mobility loss and improved functional performance compared to control. Methods and Results One hundred ninety‐four PAD participants were randomized. During months 1 to 6, the intervention group met weekly with other PAD participants and a facilitator. Group support and self‐regulatory skills were used to help participants adhere to walking exercise. Ninety‐percent of exercise was conducted at or near home. The control group attended weekly lectures. During months 6 to 12, each group received telephone contact only. Primary outcomes have been reported. Here we compare changes in exploratory outcomes of mobility loss (the inability to climb a flight of stairs or walk one‐quarter mile without assistance), walking velocity, and the Short Physical Performance Battery. Compared to controls, fewer participants randomized to the intervention experienced mobility loss at 6‐month follow‐up: 6.3% versus 26.5%, P=0.002, odds ratio=0.19 (95% CI=0.06 to 0.58) and at 12‐month follow‐up: 5.2% versus 18.5%, P=0.029, odds ratio=0.24 (95% CI=0.06 to 0.97). The intervention improved fast‐paced 4‐m walking velocity at 6‐month follow‐up (P=0.005) and the Short Physical Performance Battery at 12‐month follow‐up (P=0.027), compared to controls. Conclusions In exploratory analyses, a group‐mediated cognitive behavioral intervention promoting unsupervised walking exercise prevented mobility loss and improved functioning at 6‐ and 12‐month follow‐up in PAD patients. Clinical Trial Registration URL: http://clinicaltrials.gov. Unique identifier: NCT00693940. |
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Unsupervised Exercise and Mobility Loss in Peripheral Artery Disease: A Randomized Controlled Trial |
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https://doi.org/10.1161/JAHA.114.001659 https://doaj.org/article/ec2ef63958634b82b57a16c582cd2058 https://doaj.org/toc/2047-9980 |
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Jack M. Guralnik Michael H. Criqui Luigi Ferrucci Kiang Liu Bonnie Spring Lu Tian Kathryn Domanchuk Melina Kibbe Lihui Zhao Donald Lloyd Jones Yihua Liao Ying Gao W. Jack Rejeski |
author2Str |
Jack M. Guralnik Michael H. Criqui Luigi Ferrucci Kiang Liu Bonnie Spring Lu Tian Kathryn Domanchuk Melina Kibbe Lihui Zhao Donald Lloyd Jones Yihua Liao Ying Gao W. Jack Rejeski |
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RC - Internal Medicine |
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10.1161/JAHA.114.001659 |
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RC666-701 |
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2024-07-04T01:28:42.679Z |
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McDermott</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Unsupervised Exercise and Mobility Loss in Peripheral Artery Disease: A Randomized Controlled Trial</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2015</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background Few medical therapies improve lower extremity functioning in people with lower extremity peripheral artery disease (PAD). Among people with PAD, we studied whether a group‐mediated cognitive behavioral intervention promoting home‐based unsupervised exercise prevented mobility loss and improved functional performance compared to control. Methods and Results One hundred ninety‐four PAD participants were randomized. During months 1 to 6, the intervention group met weekly with other PAD participants and a facilitator. Group support and self‐regulatory skills were used to help participants adhere to walking exercise. Ninety‐percent of exercise was conducted at or near home. The control group attended weekly lectures. During months 6 to 12, each group received telephone contact only. Primary outcomes have been reported. Here we compare changes in exploratory outcomes of mobility loss (the inability to climb a flight of stairs or walk one‐quarter mile without assistance), walking velocity, and the Short Physical Performance Battery. Compared to controls, fewer participants randomized to the intervention experienced mobility loss at 6‐month follow‐up: 6.3% versus 26.5%, P=0.002, odds ratio=0.19 (95% CI=0.06 to 0.58) and at 12‐month follow‐up: 5.2% versus 18.5%, P=0.029, odds ratio=0.24 (95% CI=0.06 to 0.97). The intervention improved fast‐paced 4‐m walking velocity at 6‐month follow‐up (P=0.005) and the Short Physical Performance Battery at 12‐month follow‐up (P=0.027), compared to controls. Conclusions In exploratory analyses, a group‐mediated cognitive behavioral intervention promoting unsupervised walking exercise prevented mobility loss and improved functioning at 6‐ and 12‐month follow‐up in PAD patients. Clinical Trial Registration URL: http://clinicaltrials.gov. 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