Chronic Wasting Disease Prion Strain Emergence and Host Range Expansion
Human and mouse prion proteins share a structural motif that regulates resistance to common chronic wasting disease (CWD) prion strains. Successful transmission of an emergent strain of CWD prion, H95+, into mice resulted in infection. Thus, emergent CWD prion strains may have higher zoonotic potent...
Ausführliche Beschreibung
Autor*in: |
Allen Herbst [verfasserIn] Camilo Duque Velásquez [verfasserIn] Elizabeth Triscott [verfasserIn] Judd M. Aiken [verfasserIn] Debbie McKenzie [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2017 |
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Schlagwörter: |
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Übergeordnetes Werk: |
In: Emerging Infectious Diseases - Centers for Disease Control and Prevention, 2003, 23(2017), 9, Seite 1598-1600 |
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Übergeordnetes Werk: |
volume:23 ; year:2017 ; number:9 ; pages:1598-1600 |
Links: |
Link aufrufen |
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DOI / URN: |
10.3201/eid2309.161474 |
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Katalog-ID: |
DOAJ032983832 |
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Chronic Wasting Disease Prion Strain Emergence and Host Range Expansion |
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Human and mouse prion proteins share a structural motif that regulates resistance to common chronic wasting disease (CWD) prion strains. Successful transmission of an emergent strain of CWD prion, H95+, into mice resulted in infection. Thus, emergent CWD prion strains may have higher zoonotic potential than common strains. |
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Human and mouse prion proteins share a structural motif that regulates resistance to common chronic wasting disease (CWD) prion strains. Successful transmission of an emergent strain of CWD prion, H95+, into mice resulted in infection. Thus, emergent CWD prion strains may have higher zoonotic potential than common strains. |
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Human and mouse prion proteins share a structural motif that regulates resistance to common chronic wasting disease (CWD) prion strains. Successful transmission of an emergent strain of CWD prion, H95+, into mice resulted in infection. Thus, emergent CWD prion strains may have higher zoonotic potential than common strains. |
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