Identification and Characterization of α-Glucosidase Inhibition Flavonol Glycosides from Jack Bean (<i<Canavalia ensiformis</i< (L.) DC

Although the intake of jack bean (<i<Canavalia ensiformis</i< (L.) DC.), an underutilized tropical legume, can potentially decrease the risk of several chronic diseases, not much effort has been directed at profiling the polyphenolics contained therein. Hence, this work aimed to identify...
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Gespeichert in:

Autor*in:	Anita M. Sutedja [verfasserIn] Emiko Yanase [verfasserIn] Irmanida Batubara [verfasserIn] Dedi Fardiaz [verfasserIn] Hanifah N. Lioe [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2020

Schlagwörter:	legume jack bean constituent profiling flavonol glycosides flavonoid

Übergeordnetes Werk:	In: Molecules - MDPI AG, 2003, 25(2020), 11, p 2481
Übergeordnetes Werk:	volume:25 ; year:2020 ; number:11, p 2481

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/molecules25112481

Katalog-ID:	DOAJ033115354

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allfieldsGer	10.3390/molecules25112481 doi (DE-627)DOAJ033115354 (DE-599)DOAJ81a938118e7249b6a76f71f1f37e7132 DE-627 ger DE-627 rakwb eng QD241-441 Anita M. Sutedja verfasserin aut Identification and Characterization of α-Glucosidase Inhibition Flavonol Glycosides from Jack Bean (<i<Canavalia ensiformis</i< (L.) DC 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Although the intake of jack bean (<i<Canavalia ensiformis</i< (L.) DC.), an underutilized tropical legume, can potentially decrease the risk of several chronic diseases, not much effort has been directed at profiling the polyphenolics contained therein. Hence, this work aimed to identify and quantify the dominant jack bean polyphenolics, which are believed to have antioxidant and other bioactivities. Four major compounds were detected and identified as kaempferol glycosides with three or four glycoside units. Their structures were established based on UV-visible, 1D, 2D NMR, and HR-ESI-MS analyses. Specifically, kaempferol 3-O-α-<span style="font-variant: small-caps;"<l</span<-rhamnopyranosyl (1→6)- β-<span style="font-variant: small-caps;"<d</span<-glucopyranosyl (1→2)-β-<span style="font-variant: small-caps;"<d</span<-galactopyranosyl-7-O-[3-O-<i<o</i<-anisoyl]-α-<span style="font-variant: small-caps;"<l</span<-rhamnopyranoside was detected for the first time, while the other three compounds have already been described in plants other than jack bean. This new compound was found to have a higher α-glucosidase inhibition activity compared to acarbose. <i<Canavalia ensiformis</i< legume jack bean constituent profiling flavonol glycosides flavonoid Organic chemistry Emiko Yanase verfasserin aut Irmanida Batubara verfasserin aut Dedi Fardiaz verfasserin aut Hanifah N. Lioe verfasserin aut In Molecules MDPI AG, 2003 25(2020), 11, p 2481 (DE-627)311313132 (DE-600)2008644-1 14203049 nnns volume:25 year:2020 number:11, p 2481 https://doi.org/10.3390/molecules25112481 kostenfrei https://doaj.org/article/81a938118e7249b6a76f71f1f37e7132 kostenfrei https://www.mdpi.com/1420-3049/25/11/2481 kostenfrei https://doaj.org/toc/1420-3049 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 25 2020 11, p 2481
allfieldsSound	10.3390/molecules25112481 doi (DE-627)DOAJ033115354 (DE-599)DOAJ81a938118e7249b6a76f71f1f37e7132 DE-627 ger DE-627 rakwb eng QD241-441 Anita M. Sutedja verfasserin aut Identification and Characterization of α-Glucosidase Inhibition Flavonol Glycosides from Jack Bean (<i<Canavalia ensiformis</i< (L.) DC 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Although the intake of jack bean (<i<Canavalia ensiformis</i< (L.) DC.), an underutilized tropical legume, can potentially decrease the risk of several chronic diseases, not much effort has been directed at profiling the polyphenolics contained therein. Hence, this work aimed to identify and quantify the dominant jack bean polyphenolics, which are believed to have antioxidant and other bioactivities. Four major compounds were detected and identified as kaempferol glycosides with three or four glycoside units. Their structures were established based on UV-visible, 1D, 2D NMR, and HR-ESI-MS analyses. Specifically, kaempferol 3-O-α-<span style="font-variant: small-caps;"<l</span<-rhamnopyranosyl (1→6)- β-<span style="font-variant: small-caps;"<d</span<-glucopyranosyl (1→2)-β-<span style="font-variant: small-caps;"<d</span<-galactopyranosyl-7-O-[3-O-<i<o</i<-anisoyl]-α-<span style="font-variant: small-caps;"<l</span<-rhamnopyranoside was detected for the first time, while the other three compounds have already been described in plants other than jack bean. This new compound was found to have a higher α-glucosidase inhibition activity compared to acarbose. <i<Canavalia ensiformis</i< legume jack bean constituent profiling flavonol glycosides flavonoid Organic chemistry Emiko Yanase verfasserin aut Irmanida Batubara verfasserin aut Dedi Fardiaz verfasserin aut Hanifah N. Lioe verfasserin aut In Molecules MDPI AG, 2003 25(2020), 11, p 2481 (DE-627)311313132 (DE-600)2008644-1 14203049 nnns volume:25 year:2020 number:11, p 2481 https://doi.org/10.3390/molecules25112481 kostenfrei https://doaj.org/article/81a938118e7249b6a76f71f1f37e7132 kostenfrei https://www.mdpi.com/1420-3049/25/11/2481 kostenfrei https://doaj.org/toc/1420-3049 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 25 2020 11, p 2481
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callnumber-first	Q - Science
author	Anita M. Sutedja
spellingShingle	Anita M. Sutedja misc QD241-441 misc <i<Canavalia ensiformis</i< misc legume misc jack bean misc constituent profiling misc flavonol glycosides misc flavonoid misc Organic chemistry Identification and Characterization of α-Glucosidase Inhibition Flavonol Glycosides from Jack Bean (<i<Canavalia ensiformis</i< (L.) DC
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topic_title	QD241-441 Identification and Characterization of α-Glucosidase Inhibition Flavonol Glycosides from Jack Bean (<i<Canavalia ensiformis</i< (L.) DC <i<Canavalia ensiformis</i< legume jack bean constituent profiling flavonol glycosides flavonoid
topic	misc QD241-441 misc <i<Canavalia ensiformis</i< misc legume misc jack bean misc constituent profiling misc flavonol glycosides misc flavonoid misc Organic chemistry
topic_unstemmed	misc QD241-441 misc <i<Canavalia ensiformis</i< misc legume misc jack bean misc constituent profiling misc flavonol glycosides misc flavonoid misc Organic chemistry
topic_browse	misc QD241-441 misc <i<Canavalia ensiformis</i< misc legume misc jack bean misc constituent profiling misc flavonol glycosides misc flavonoid misc Organic chemistry
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title	Identification and Characterization of α-Glucosidase Inhibition Flavonol Glycosides from Jack Bean (<i<Canavalia ensiformis</i< (L.) DC
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title_full	Identification and Characterization of α-Glucosidase Inhibition Flavonol Glycosides from Jack Bean (<i<Canavalia ensiformis</i< (L.) DC
author_sort	Anita M. Sutedja
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author_browse	Anita M. Sutedja Emiko Yanase Irmanida Batubara Dedi Fardiaz Hanifah N. Lioe
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title_sort	identification and characterization of α-glucosidase inhibition flavonol glycosides from jack bean (<i<canavalia ensiformis</i< (l.) dc
callnumber	QD241-441
title_auth	Identification and Characterization of α-Glucosidase Inhibition Flavonol Glycosides from Jack Bean (<i<Canavalia ensiformis</i< (L.) DC
abstract	Although the intake of jack bean (<i<Canavalia ensiformis</i< (L.) DC.), an underutilized tropical legume, can potentially decrease the risk of several chronic diseases, not much effort has been directed at profiling the polyphenolics contained therein. Hence, this work aimed to identify and quantify the dominant jack bean polyphenolics, which are believed to have antioxidant and other bioactivities. Four major compounds were detected and identified as kaempferol glycosides with three or four glycoside units. Their structures were established based on UV-visible, 1D, 2D NMR, and HR-ESI-MS analyses. Specifically, kaempferol 3-O-α-<span style="font-variant: small-caps;"<l</span<-rhamnopyranosyl (1→6)- β-<span style="font-variant: small-caps;"<d</span<-glucopyranosyl (1→2)-β-<span style="font-variant: small-caps;"<d</span<-galactopyranosyl-7-O-[3-O-<i<o</i<-anisoyl]-α-<span style="font-variant: small-caps;"<l</span<-rhamnopyranoside was detected for the first time, while the other three compounds have already been described in plants other than jack bean. This new compound was found to have a higher α-glucosidase inhibition activity compared to acarbose.
abstractGer	Although the intake of jack bean (<i<Canavalia ensiformis</i< (L.) DC.), an underutilized tropical legume, can potentially decrease the risk of several chronic diseases, not much effort has been directed at profiling the polyphenolics contained therein. Hence, this work aimed to identify and quantify the dominant jack bean polyphenolics, which are believed to have antioxidant and other bioactivities. Four major compounds were detected and identified as kaempferol glycosides with three or four glycoside units. Their structures were established based on UV-visible, 1D, 2D NMR, and HR-ESI-MS analyses. Specifically, kaempferol 3-O-α-<span style="font-variant: small-caps;"<l</span<-rhamnopyranosyl (1→6)- β-<span style="font-variant: small-caps;"<d</span<-glucopyranosyl (1→2)-β-<span style="font-variant: small-caps;"<d</span<-galactopyranosyl-7-O-[3-O-<i<o</i<-anisoyl]-α-<span style="font-variant: small-caps;"<l</span<-rhamnopyranoside was detected for the first time, while the other three compounds have already been described in plants other than jack bean. This new compound was found to have a higher α-glucosidase inhibition activity compared to acarbose.
abstract_unstemmed	Although the intake of jack bean (<i<Canavalia ensiformis</i< (L.) DC.), an underutilized tropical legume, can potentially decrease the risk of several chronic diseases, not much effort has been directed at profiling the polyphenolics contained therein. Hence, this work aimed to identify and quantify the dominant jack bean polyphenolics, which are believed to have antioxidant and other bioactivities. Four major compounds were detected and identified as kaempferol glycosides with three or four glycoside units. Their structures were established based on UV-visible, 1D, 2D NMR, and HR-ESI-MS analyses. Specifically, kaempferol 3-O-α-<span style="font-variant: small-caps;"<l</span<-rhamnopyranosyl (1→6)- β-<span style="font-variant: small-caps;"<d</span<-glucopyranosyl (1→2)-β-<span style="font-variant: small-caps;"<d</span<-galactopyranosyl-7-O-[3-O-<i<o</i<-anisoyl]-α-<span style="font-variant: small-caps;"<l</span<-rhamnopyranoside was detected for the first time, while the other three compounds have already been described in plants other than jack bean. This new compound was found to have a higher α-glucosidase inhibition activity compared to acarbose.
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container_issue	11, p 2481
title_short	Identification and Characterization of α-Glucosidase Inhibition Flavonol Glycosides from Jack Bean (<i<Canavalia ensiformis</i< (L.) DC
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author2	Emiko Yanase Irmanida Batubara Dedi Fardiaz Hanifah N. Lioe
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Hence, this work aimed to identify and quantify the dominant jack bean polyphenolics, which are believed to have antioxidant and other bioactivities. Four major compounds were detected and identified as kaempferol glycosides with three or four glycoside units. Their structures were established based on UV-visible, 1D, 2D NMR, and HR-ESI-MS analyses. Specifically, kaempferol 3-O-α-<span style="font-variant: small-caps;"<l</span<-rhamnopyranosyl (1→6)- β-<span style="font-variant: small-caps;"<d</span<-glucopyranosyl (1→2)-β-<span style="font-variant: small-caps;"<d</span<-galactopyranosyl-7-O-[3-O-<i<o</i<-anisoyl]-α-<span style="font-variant: small-caps;"<l</span<-rhamnopyranoside was detected for the first time, while the other three compounds have already been described in plants other than jack bean. 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Identification and Characterization of α-Glucosidase Inhibition Flavonol Glycosides from Jack Bean (<i<Canavalia ensiformis</i< (L.) DC

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