Nuclear magnetic resonance spectroscopy based metabolomics to identify novel biomarkers of alcohol-dependence

Alcohol misuse is a ravaging public health and social problem. Its harm can affect the drinkers and the whole society. Alcohol-dependence is a phase of alcohol misuse in which the drinker consumes excessive amounts of alcohol and has a continuous urge to consume alcohol. Current methods of alcohol d...
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Autor*in:	Hamza Mostafa [verfasserIn] Arwa M. Amin [verfasserIn] Nor Hayati Arif [verfasserIn] Vikneswaran a/l Murugaiyah [verfasserIn] Baharudin Ibrahim [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2017

Schlagwörter:	alcohol-dependence diagnosis metabolomics metabotype nuclear magnetic resonance

Übergeordnetes Werk:	In: Songklanakarin Journal of Science and Technology (SJST) - Prince of Songkla University, 2005, 39(2017), 2, Seite 153-162
Übergeordnetes Werk:	volume:39 ; year:2017 ; number:2 ; pages:153-162

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.14456/sjst-psu.2017.18

Katalog-ID:	DOAJ033448396

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author	Hamza Mostafa
spellingShingle	Hamza Mostafa misc T1-995 misc Q1-390 misc alcohol-dependence misc diagnosis misc metabolomics misc metabotype misc nuclear magnetic resonance misc Technology misc T misc Technology (General) misc Science misc Q misc Science (General) Nuclear magnetic resonance spectroscopy based metabolomics to identify novel biomarkers of alcohol-dependence
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title	Nuclear magnetic resonance spectroscopy based metabolomics to identify novel biomarkers of alcohol-dependence
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title_full	Nuclear magnetic resonance spectroscopy based metabolomics to identify novel biomarkers of alcohol-dependence
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title_auth	Nuclear magnetic resonance spectroscopy based metabolomics to identify novel biomarkers of alcohol-dependence
abstract	Alcohol misuse is a ravaging public health and social problem. Its harm can affect the drinkers and the whole society. Alcohol-dependence is a phase of alcohol misuse in which the drinker consumes excessive amounts of alcohol and has a continuous urge to consume alcohol. Current methods of alcohol dependence diagnoses are questionnaires and some biomarkers. However, both methods lack specificity and sensitivity. Metabolomics is a scientific field which deals with the identification and the quantification of the metabolites present in the metabolome using spectroscopic techniques such as nuclear magnetic resonance (NMR). Metabolomics helps to indicate the perturbation in the levels of metabolites in cells and tissues due to diseases or ingestion of any substances. NMR is one of the most widely used spectroscopic techniques in metabolomics because of its reproducibility and speed. Some recent metabolomics studies were conducted on alcohol consumption and alcohol misuse in animals and humans. However, few focused on identifying alcohol dependence novel biomarkers. A sensitive and specific technique such as NMR based metabolomics applied to find novel biomarkers in plasma and urine can be useful to diagnose alcohol-dependence.
abstractGer	Alcohol misuse is a ravaging public health and social problem. Its harm can affect the drinkers and the whole society. Alcohol-dependence is a phase of alcohol misuse in which the drinker consumes excessive amounts of alcohol and has a continuous urge to consume alcohol. Current methods of alcohol dependence diagnoses are questionnaires and some biomarkers. However, both methods lack specificity and sensitivity. Metabolomics is a scientific field which deals with the identification and the quantification of the metabolites present in the metabolome using spectroscopic techniques such as nuclear magnetic resonance (NMR). Metabolomics helps to indicate the perturbation in the levels of metabolites in cells and tissues due to diseases or ingestion of any substances. NMR is one of the most widely used spectroscopic techniques in metabolomics because of its reproducibility and speed. Some recent metabolomics studies were conducted on alcohol consumption and alcohol misuse in animals and humans. However, few focused on identifying alcohol dependence novel biomarkers. A sensitive and specific technique such as NMR based metabolomics applied to find novel biomarkers in plasma and urine can be useful to diagnose alcohol-dependence.
abstract_unstemmed	Alcohol misuse is a ravaging public health and social problem. Its harm can affect the drinkers and the whole society. Alcohol-dependence is a phase of alcohol misuse in which the drinker consumes excessive amounts of alcohol and has a continuous urge to consume alcohol. Current methods of alcohol dependence diagnoses are questionnaires and some biomarkers. However, both methods lack specificity and sensitivity. Metabolomics is a scientific field which deals with the identification and the quantification of the metabolites present in the metabolome using spectroscopic techniques such as nuclear magnetic resonance (NMR). Metabolomics helps to indicate the perturbation in the levels of metabolites in cells and tissues due to diseases or ingestion of any substances. NMR is one of the most widely used spectroscopic techniques in metabolomics because of its reproducibility and speed. Some recent metabolomics studies were conducted on alcohol consumption and alcohol misuse in animals and humans. However, few focused on identifying alcohol dependence novel biomarkers. A sensitive and specific technique such as NMR based metabolomics applied to find novel biomarkers in plasma and urine can be useful to diagnose alcohol-dependence.
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title_short	Nuclear magnetic resonance spectroscopy based metabolomics to identify novel biomarkers of alcohol-dependence
url	https://doi.org/10.14456/sjst-psu.2017.18 https://doaj.org/article/dfe0878394374cd8be883ca4e69368c0 http://rdo.psu.ac.th/sjstweb/journal/39-2/39-2-3.pdf https://doaj.org/toc/0125-3395
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up_date	2024-07-03T17:48:35.063Z
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Its harm can affect the drinkers and the whole society. Alcohol-dependence is a phase of alcohol misuse in which the drinker consumes excessive amounts of alcohol and has a continuous urge to consume alcohol. Current methods of alcohol dependence diagnoses are questionnaires and some biomarkers. However, both methods lack specificity and sensitivity. Metabolomics is a scientific field which deals with the identification and the quantification of the metabolites present in the metabolome using spectroscopic techniques such as nuclear magnetic resonance (NMR). Metabolomics helps to indicate the perturbation in the levels of metabolites in cells and tissues due to diseases or ingestion of any substances. NMR is one of the most widely used spectroscopic techniques in metabolomics because of its reproducibility and speed. Some recent metabolomics studies were conducted on alcohol consumption and alcohol misuse in animals and humans. 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A sensitive and specific technique such as NMR based metabolomics applied to find novel biomarkers in plasma and urine can be useful to diagnose alcohol-dependence.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">alcohol-dependence</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">diagnosis</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">metabolomics</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">metabotype</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">nuclear magnetic resonance</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Technology</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">T</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Technology (General)</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Science</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Q</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Science (General)</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Arwa M. 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Nuclear magnetic resonance spectroscopy based metabolomics to identify novel biomarkers of alcohol-dependence

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