Association of fat mass index versus appendicular lean mass index with physical function – The Yishun Study

Background: Increase in body fat and reduced muscle mass are common body composition changes with age and precedes functional impairment. However, it remains unclear whether increased adiposity or less lean mass is a stronger determinant of worse functional performance. This study compared the assoc...
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Autor*in:	Nien Xiang Tou [verfasserIn] Shiou Liang Wee [verfasserIn] Benedict Wei Jun Pang [verfasserIn] Lay Khoon Lau [verfasserIn] Khalid Abdul Jabbar [verfasserIn] Wei Ting Seah [verfasserIn] Kenneth Kexun Chen [verfasserIn] Tze Pin Ng [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022

Schlagwörter:	Aging Body composition Physical performance Fat mass index Appendicular lean mass index

Übergeordnetes Werk:	In: Aging and Health Research - Elsevier, 2021, 2(2022), 3, Seite 100097-
Übergeordnetes Werk:	volume:2 ; year:2022 ; number:3 ; pages:100097-

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1016/j.ahr.2022.100097

Katalog-ID:	DOAJ033471800

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245	1	0	\|a Association of fat mass index versus appendicular lean mass index with physical function – The Yishun Study
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520			\|a Background: Increase in body fat and reduced muscle mass are common body composition changes with age and precedes functional impairment. However, it remains unclear whether increased adiposity or less lean mass is a stronger determinant of worse functional performance. This study compared the association between fat versus lean mass indices with physical function among community-dwelling adults after adjusting for age and muscle strength. Methods: 542 community-dwelling adults aged between 21 and 90 years were recruited. All participants were assessed for body composition (dual X-ray absorptiometry), knee extensor strength (KES) and physical function. Fat mass and lean mass (weight in kg) were adjusted by height (in meters) squared - measured as fat mass index (FMI) and appendicular lean mass index (ALMI), respectively. Physical function was assessed using the Short Physical Performance Battery (SPPB) and the timed up and go (TUG) test. Results: FMI was significantly associated with both SPPB (ß = -0.130, p = 0.019) and TUG (ß = 0.182, p < 0.01) after accounting for ALMI and other covariates. This association was moderated by age and KES. FMI was associated with SPPB and TUG in individuals who are older or with weaker KES. While ALMI was found to be significantly associated with TUG (ß = 0.121, p = 0.023), no significant association was found between ALMI and physical function after accounting for FMI. Conclusions: Our results show that FMI is a stronger determinant of physical function than ALMI. This emphasizes the importance of reducing body fat to mitigate functional decline especially in older and weaker adults.
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650		4	\|a Body composition
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650		4	\|a Fat mass index
650		4	\|a Appendicular lean mass index
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700	0		\|a Shiou Liang Wee \|e verfasserin \|4 aut
700	0		\|a Benedict Wei Jun Pang \|e verfasserin \|4 aut
700	0		\|a Lay Khoon Lau \|e verfasserin \|4 aut
700	0		\|a Khalid Abdul Jabbar \|e verfasserin \|4 aut
700	0		\|a Wei Ting Seah \|e verfasserin \|4 aut
700	0		\|a Kenneth Kexun Chen \|e verfasserin \|4 aut
700	0		\|a Tze Pin Ng \|e verfasserin \|4 aut
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allfields	10.1016/j.ahr.2022.100097 doi (DE-627)DOAJ033471800 (DE-599)DOAJ8da574f8e9fe43a99398888eae000cdf DE-627 ger DE-627 rakwb eng RC952-954.6 Nien Xiang Tou verfasserin aut Association of fat mass index versus appendicular lean mass index with physical function – The Yishun Study 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Increase in body fat and reduced muscle mass are common body composition changes with age and precedes functional impairment. However, it remains unclear whether increased adiposity or less lean mass is a stronger determinant of worse functional performance. This study compared the association between fat versus lean mass indices with physical function among community-dwelling adults after adjusting for age and muscle strength. Methods: 542 community-dwelling adults aged between 21 and 90 years were recruited. All participants were assessed for body composition (dual X-ray absorptiometry), knee extensor strength (KES) and physical function. Fat mass and lean mass (weight in kg) were adjusted by height (in meters) squared - measured as fat mass index (FMI) and appendicular lean mass index (ALMI), respectively. Physical function was assessed using the Short Physical Performance Battery (SPPB) and the timed up and go (TUG) test. Results: FMI was significantly associated with both SPPB (ß = -0.130, p = 0.019) and TUG (ß = 0.182, p < 0.01) after accounting for ALMI and other covariates. This association was moderated by age and KES. FMI was associated with SPPB and TUG in individuals who are older or with weaker KES. While ALMI was found to be significantly associated with TUG (ß = 0.121, p = 0.023), no significant association was found between ALMI and physical function after accounting for FMI. Conclusions: Our results show that FMI is a stronger determinant of physical function than ALMI. This emphasizes the importance of reducing body fat to mitigate functional decline especially in older and weaker adults. Aging Body composition Physical performance Fat mass index Appendicular lean mass index Geriatrics Shiou Liang Wee verfasserin aut Benedict Wei Jun Pang verfasserin aut Lay Khoon Lau verfasserin aut Khalid Abdul Jabbar verfasserin aut Wei Ting Seah verfasserin aut Kenneth Kexun Chen verfasserin aut Tze Pin Ng verfasserin aut In Aging and Health Research Elsevier, 2021 2(2022), 3, Seite 100097- (DE-627)176129976X 26670321 nnns volume:2 year:2022 number:3 pages:100097- https://doi.org/10.1016/j.ahr.2022.100097 kostenfrei https://doaj.org/article/8da574f8e9fe43a99398888eae000cdf kostenfrei http://www.sciencedirect.com/science/article/pii/S2667032122000439 kostenfrei https://doaj.org/toc/2667-0321 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 2 2022 3 100097-
spelling	10.1016/j.ahr.2022.100097 doi (DE-627)DOAJ033471800 (DE-599)DOAJ8da574f8e9fe43a99398888eae000cdf DE-627 ger DE-627 rakwb eng RC952-954.6 Nien Xiang Tou verfasserin aut Association of fat mass index versus appendicular lean mass index with physical function – The Yishun Study 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Increase in body fat and reduced muscle mass are common body composition changes with age and precedes functional impairment. However, it remains unclear whether increased adiposity or less lean mass is a stronger determinant of worse functional performance. This study compared the association between fat versus lean mass indices with physical function among community-dwelling adults after adjusting for age and muscle strength. Methods: 542 community-dwelling adults aged between 21 and 90 years were recruited. All participants were assessed for body composition (dual X-ray absorptiometry), knee extensor strength (KES) and physical function. Fat mass and lean mass (weight in kg) were adjusted by height (in meters) squared - measured as fat mass index (FMI) and appendicular lean mass index (ALMI), respectively. Physical function was assessed using the Short Physical Performance Battery (SPPB) and the timed up and go (TUG) test. Results: FMI was significantly associated with both SPPB (ß = -0.130, p = 0.019) and TUG (ß = 0.182, p < 0.01) after accounting for ALMI and other covariates. This association was moderated by age and KES. FMI was associated with SPPB and TUG in individuals who are older or with weaker KES. While ALMI was found to be significantly associated with TUG (ß = 0.121, p = 0.023), no significant association was found between ALMI and physical function after accounting for FMI. Conclusions: Our results show that FMI is a stronger determinant of physical function than ALMI. This emphasizes the importance of reducing body fat to mitigate functional decline especially in older and weaker adults. Aging Body composition Physical performance Fat mass index Appendicular lean mass index Geriatrics Shiou Liang Wee verfasserin aut Benedict Wei Jun Pang verfasserin aut Lay Khoon Lau verfasserin aut Khalid Abdul Jabbar verfasserin aut Wei Ting Seah verfasserin aut Kenneth Kexun Chen verfasserin aut Tze Pin Ng verfasserin aut In Aging and Health Research Elsevier, 2021 2(2022), 3, Seite 100097- (DE-627)176129976X 26670321 nnns volume:2 year:2022 number:3 pages:100097- https://doi.org/10.1016/j.ahr.2022.100097 kostenfrei https://doaj.org/article/8da574f8e9fe43a99398888eae000cdf kostenfrei http://www.sciencedirect.com/science/article/pii/S2667032122000439 kostenfrei https://doaj.org/toc/2667-0321 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 2 2022 3 100097-
allfields_unstemmed	10.1016/j.ahr.2022.100097 doi (DE-627)DOAJ033471800 (DE-599)DOAJ8da574f8e9fe43a99398888eae000cdf DE-627 ger DE-627 rakwb eng RC952-954.6 Nien Xiang Tou verfasserin aut Association of fat mass index versus appendicular lean mass index with physical function – The Yishun Study 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Increase in body fat and reduced muscle mass are common body composition changes with age and precedes functional impairment. However, it remains unclear whether increased adiposity or less lean mass is a stronger determinant of worse functional performance. This study compared the association between fat versus lean mass indices with physical function among community-dwelling adults after adjusting for age and muscle strength. Methods: 542 community-dwelling adults aged between 21 and 90 years were recruited. All participants were assessed for body composition (dual X-ray absorptiometry), knee extensor strength (KES) and physical function. Fat mass and lean mass (weight in kg) were adjusted by height (in meters) squared - measured as fat mass index (FMI) and appendicular lean mass index (ALMI), respectively. Physical function was assessed using the Short Physical Performance Battery (SPPB) and the timed up and go (TUG) test. Results: FMI was significantly associated with both SPPB (ß = -0.130, p = 0.019) and TUG (ß = 0.182, p < 0.01) after accounting for ALMI and other covariates. This association was moderated by age and KES. FMI was associated with SPPB and TUG in individuals who are older or with weaker KES. While ALMI was found to be significantly associated with TUG (ß = 0.121, p = 0.023), no significant association was found between ALMI and physical function after accounting for FMI. Conclusions: Our results show that FMI is a stronger determinant of physical function than ALMI. This emphasizes the importance of reducing body fat to mitigate functional decline especially in older and weaker adults. Aging Body composition Physical performance Fat mass index Appendicular lean mass index Geriatrics Shiou Liang Wee verfasserin aut Benedict Wei Jun Pang verfasserin aut Lay Khoon Lau verfasserin aut Khalid Abdul Jabbar verfasserin aut Wei Ting Seah verfasserin aut Kenneth Kexun Chen verfasserin aut Tze Pin Ng verfasserin aut In Aging and Health Research Elsevier, 2021 2(2022), 3, Seite 100097- (DE-627)176129976X 26670321 nnns volume:2 year:2022 number:3 pages:100097- https://doi.org/10.1016/j.ahr.2022.100097 kostenfrei https://doaj.org/article/8da574f8e9fe43a99398888eae000cdf kostenfrei http://www.sciencedirect.com/science/article/pii/S2667032122000439 kostenfrei https://doaj.org/toc/2667-0321 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 2 2022 3 100097-
allfieldsGer	10.1016/j.ahr.2022.100097 doi (DE-627)DOAJ033471800 (DE-599)DOAJ8da574f8e9fe43a99398888eae000cdf DE-627 ger DE-627 rakwb eng RC952-954.6 Nien Xiang Tou verfasserin aut Association of fat mass index versus appendicular lean mass index with physical function – The Yishun Study 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Increase in body fat and reduced muscle mass are common body composition changes with age and precedes functional impairment. However, it remains unclear whether increased adiposity or less lean mass is a stronger determinant of worse functional performance. This study compared the association between fat versus lean mass indices with physical function among community-dwelling adults after adjusting for age and muscle strength. Methods: 542 community-dwelling adults aged between 21 and 90 years were recruited. All participants were assessed for body composition (dual X-ray absorptiometry), knee extensor strength (KES) and physical function. Fat mass and lean mass (weight in kg) were adjusted by height (in meters) squared - measured as fat mass index (FMI) and appendicular lean mass index (ALMI), respectively. Physical function was assessed using the Short Physical Performance Battery (SPPB) and the timed up and go (TUG) test. Results: FMI was significantly associated with both SPPB (ß = -0.130, p = 0.019) and TUG (ß = 0.182, p < 0.01) after accounting for ALMI and other covariates. This association was moderated by age and KES. FMI was associated with SPPB and TUG in individuals who are older or with weaker KES. While ALMI was found to be significantly associated with TUG (ß = 0.121, p = 0.023), no significant association was found between ALMI and physical function after accounting for FMI. Conclusions: Our results show that FMI is a stronger determinant of physical function than ALMI. This emphasizes the importance of reducing body fat to mitigate functional decline especially in older and weaker adults. Aging Body composition Physical performance Fat mass index Appendicular lean mass index Geriatrics Shiou Liang Wee verfasserin aut Benedict Wei Jun Pang verfasserin aut Lay Khoon Lau verfasserin aut Khalid Abdul Jabbar verfasserin aut Wei Ting Seah verfasserin aut Kenneth Kexun Chen verfasserin aut Tze Pin Ng verfasserin aut In Aging and Health Research Elsevier, 2021 2(2022), 3, Seite 100097- (DE-627)176129976X 26670321 nnns volume:2 year:2022 number:3 pages:100097- https://doi.org/10.1016/j.ahr.2022.100097 kostenfrei https://doaj.org/article/8da574f8e9fe43a99398888eae000cdf kostenfrei http://www.sciencedirect.com/science/article/pii/S2667032122000439 kostenfrei https://doaj.org/toc/2667-0321 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 2 2022 3 100097-
allfieldsSound	10.1016/j.ahr.2022.100097 doi (DE-627)DOAJ033471800 (DE-599)DOAJ8da574f8e9fe43a99398888eae000cdf DE-627 ger DE-627 rakwb eng RC952-954.6 Nien Xiang Tou verfasserin aut Association of fat mass index versus appendicular lean mass index with physical function – The Yishun Study 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Increase in body fat and reduced muscle mass are common body composition changes with age and precedes functional impairment. However, it remains unclear whether increased adiposity or less lean mass is a stronger determinant of worse functional performance. This study compared the association between fat versus lean mass indices with physical function among community-dwelling adults after adjusting for age and muscle strength. Methods: 542 community-dwelling adults aged between 21 and 90 years were recruited. All participants were assessed for body composition (dual X-ray absorptiometry), knee extensor strength (KES) and physical function. Fat mass and lean mass (weight in kg) were adjusted by height (in meters) squared - measured as fat mass index (FMI) and appendicular lean mass index (ALMI), respectively. Physical function was assessed using the Short Physical Performance Battery (SPPB) and the timed up and go (TUG) test. Results: FMI was significantly associated with both SPPB (ß = -0.130, p = 0.019) and TUG (ß = 0.182, p < 0.01) after accounting for ALMI and other covariates. This association was moderated by age and KES. FMI was associated with SPPB and TUG in individuals who are older or with weaker KES. While ALMI was found to be significantly associated with TUG (ß = 0.121, p = 0.023), no significant association was found between ALMI and physical function after accounting for FMI. Conclusions: Our results show that FMI is a stronger determinant of physical function than ALMI. This emphasizes the importance of reducing body fat to mitigate functional decline especially in older and weaker adults. Aging Body composition Physical performance Fat mass index Appendicular lean mass index Geriatrics Shiou Liang Wee verfasserin aut Benedict Wei Jun Pang verfasserin aut Lay Khoon Lau verfasserin aut Khalid Abdul Jabbar verfasserin aut Wei Ting Seah verfasserin aut Kenneth Kexun Chen verfasserin aut Tze Pin Ng verfasserin aut In Aging and Health Research Elsevier, 2021 2(2022), 3, Seite 100097- (DE-627)176129976X 26670321 nnns volume:2 year:2022 number:3 pages:100097- https://doi.org/10.1016/j.ahr.2022.100097 kostenfrei https://doaj.org/article/8da574f8e9fe43a99398888eae000cdf kostenfrei http://www.sciencedirect.com/science/article/pii/S2667032122000439 kostenfrei https://doaj.org/toc/2667-0321 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2110 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4393 GBV_ILN_4700 AR 2 2022 3 100097-
language	English
source	In Aging and Health Research 2(2022), 3, Seite 100097- volume:2 year:2022 number:3 pages:100097-
sourceStr	In Aging and Health Research 2(2022), 3, Seite 100097- volume:2 year:2022 number:3 pages:100097-
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Aging Body composition Physical performance Fat mass index Appendicular lean mass index Geriatrics
isfreeaccess_bool	true
container_title	Aging and Health Research
authorswithroles_txt_mv	Nien Xiang Tou @@aut@@ Shiou Liang Wee @@aut@@ Benedict Wei Jun Pang @@aut@@ Lay Khoon Lau @@aut@@ Khalid Abdul Jabbar @@aut@@ Wei Ting Seah @@aut@@ Kenneth Kexun Chen @@aut@@ Tze Pin Ng @@aut@@
publishDateDaySort_date	2022-01-01T00:00:00Z
hierarchy_top_id	176129976X
id	DOAJ033471800
language_de	englisch
fullrecord	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ033471800</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230501193037.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230226s2022 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.ahr.2022.100097</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ033471800</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ8da574f8e9fe43a99398888eae000cdf</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RC952-954.6</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Nien Xiang Tou</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Association of fat mass index versus appendicular lean mass index with physical function – The Yishun Study</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2022</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background: Increase in body fat and reduced muscle mass are common body composition changes with age and precedes functional impairment. However, it remains unclear whether increased adiposity or less lean mass is a stronger determinant of worse functional performance. This study compared the association between fat versus lean mass indices with physical function among community-dwelling adults after adjusting for age and muscle strength. Methods: 542 community-dwelling adults aged between 21 and 90 years were recruited. All participants were assessed for body composition (dual X-ray absorptiometry), knee extensor strength (KES) and physical function. Fat mass and lean mass (weight in kg) were adjusted by height (in meters) squared - measured as fat mass index (FMI) and appendicular lean mass index (ALMI), respectively. Physical function was assessed using the Short Physical Performance Battery (SPPB) and the timed up and go (TUG) test. Results: FMI was significantly associated with both SPPB (ß = -0.130, p = 0.019) and TUG (ß = 0.182, p < 0.01) after accounting for ALMI and other covariates. This association was moderated by age and KES. FMI was associated with SPPB and TUG in individuals who are older or with weaker KES. While ALMI was found to be significantly associated with TUG (ß = 0.121, p = 0.023), no significant association was found between ALMI and physical function after accounting for FMI. Conclusions: Our results show that FMI is a stronger determinant of physical function than ALMI. This emphasizes the importance of reducing body fat to mitigate functional decline especially in older and weaker adults.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Aging</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Body composition</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Physical performance</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Fat mass index</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Appendicular lean mass index</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Geriatrics</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Shiou Liang Wee</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Benedict Wei Jun Pang</subfield><subfield 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callnumber-first	R - Medicine
author	Nien Xiang Tou
spellingShingle	Nien Xiang Tou misc RC952-954.6 misc Aging misc Body composition misc Physical performance misc Fat mass index misc Appendicular lean mass index misc Geriatrics Association of fat mass index versus appendicular lean mass index with physical function – The Yishun Study
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topic_title	RC952-954.6 Association of fat mass index versus appendicular lean mass index with physical function – The Yishun Study Aging Body composition Physical performance Fat mass index Appendicular lean mass index
topic	misc RC952-954.6 misc Aging misc Body composition misc Physical performance misc Fat mass index misc Appendicular lean mass index misc Geriatrics
topic_unstemmed	misc RC952-954.6 misc Aging misc Body composition misc Physical performance misc Fat mass index misc Appendicular lean mass index misc Geriatrics
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title	Association of fat mass index versus appendicular lean mass index with physical function – The Yishun Study
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title_full	Association of fat mass index versus appendicular lean mass index with physical function – The Yishun Study
author_sort	Nien Xiang Tou
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author_browse	Nien Xiang Tou Shiou Liang Wee Benedict Wei Jun Pang Lay Khoon Lau Khalid Abdul Jabbar Wei Ting Seah Kenneth Kexun Chen Tze Pin Ng
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title_sort	association of fat mass index versus appendicular lean mass index with physical function – the yishun study
callnumber	RC952-954.6
title_auth	Association of fat mass index versus appendicular lean mass index with physical function – The Yishun Study
abstract	Background: Increase in body fat and reduced muscle mass are common body composition changes with age and precedes functional impairment. However, it remains unclear whether increased adiposity or less lean mass is a stronger determinant of worse functional performance. This study compared the association between fat versus lean mass indices with physical function among community-dwelling adults after adjusting for age and muscle strength. Methods: 542 community-dwelling adults aged between 21 and 90 years were recruited. All participants were assessed for body composition (dual X-ray absorptiometry), knee extensor strength (KES) and physical function. Fat mass and lean mass (weight in kg) were adjusted by height (in meters) squared - measured as fat mass index (FMI) and appendicular lean mass index (ALMI), respectively. Physical function was assessed using the Short Physical Performance Battery (SPPB) and the timed up and go (TUG) test. Results: FMI was significantly associated with both SPPB (ß = -0.130, p = 0.019) and TUG (ß = 0.182, p < 0.01) after accounting for ALMI and other covariates. This association was moderated by age and KES. FMI was associated with SPPB and TUG in individuals who are older or with weaker KES. While ALMI was found to be significantly associated with TUG (ß = 0.121, p = 0.023), no significant association was found between ALMI and physical function after accounting for FMI. Conclusions: Our results show that FMI is a stronger determinant of physical function than ALMI. This emphasizes the importance of reducing body fat to mitigate functional decline especially in older and weaker adults.
abstractGer	Background: Increase in body fat and reduced muscle mass are common body composition changes with age and precedes functional impairment. However, it remains unclear whether increased adiposity or less lean mass is a stronger determinant of worse functional performance. This study compared the association between fat versus lean mass indices with physical function among community-dwelling adults after adjusting for age and muscle strength. Methods: 542 community-dwelling adults aged between 21 and 90 years were recruited. All participants were assessed for body composition (dual X-ray absorptiometry), knee extensor strength (KES) and physical function. Fat mass and lean mass (weight in kg) were adjusted by height (in meters) squared - measured as fat mass index (FMI) and appendicular lean mass index (ALMI), respectively. Physical function was assessed using the Short Physical Performance Battery (SPPB) and the timed up and go (TUG) test. Results: FMI was significantly associated with both SPPB (ß = -0.130, p = 0.019) and TUG (ß = 0.182, p < 0.01) after accounting for ALMI and other covariates. This association was moderated by age and KES. FMI was associated with SPPB and TUG in individuals who are older or with weaker KES. While ALMI was found to be significantly associated with TUG (ß = 0.121, p = 0.023), no significant association was found between ALMI and physical function after accounting for FMI. Conclusions: Our results show that FMI is a stronger determinant of physical function than ALMI. This emphasizes the importance of reducing body fat to mitigate functional decline especially in older and weaker adults.
abstract_unstemmed	Background: Increase in body fat and reduced muscle mass are common body composition changes with age and precedes functional impairment. However, it remains unclear whether increased adiposity or less lean mass is a stronger determinant of worse functional performance. This study compared the association between fat versus lean mass indices with physical function among community-dwelling adults after adjusting for age and muscle strength. Methods: 542 community-dwelling adults aged between 21 and 90 years were recruited. All participants were assessed for body composition (dual X-ray absorptiometry), knee extensor strength (KES) and physical function. Fat mass and lean mass (weight in kg) were adjusted by height (in meters) squared - measured as fat mass index (FMI) and appendicular lean mass index (ALMI), respectively. Physical function was assessed using the Short Physical Performance Battery (SPPB) and the timed up and go (TUG) test. Results: FMI was significantly associated with both SPPB (ß = -0.130, p = 0.019) and TUG (ß = 0.182, p < 0.01) after accounting for ALMI and other covariates. This association was moderated by age and KES. FMI was associated with SPPB and TUG in individuals who are older or with weaker KES. While ALMI was found to be significantly associated with TUG (ß = 0.121, p = 0.023), no significant association was found between ALMI and physical function after accounting for FMI. Conclusions: Our results show that FMI is a stronger determinant of physical function than ALMI. This emphasizes the importance of reducing body fat to mitigate functional decline especially in older and weaker adults.
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title_short	Association of fat mass index versus appendicular lean mass index with physical function – The Yishun Study
url	https://doi.org/10.1016/j.ahr.2022.100097 https://doaj.org/article/8da574f8e9fe43a99398888eae000cdf http://www.sciencedirect.com/science/article/pii/S2667032122000439 https://doaj.org/toc/2667-0321
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author2	Shiou Liang Wee Benedict Wei Jun Pang Lay Khoon Lau Khalid Abdul Jabbar Wei Ting Seah Kenneth Kexun Chen Tze Pin Ng
author2Str	Shiou Liang Wee Benedict Wei Jun Pang Lay Khoon Lau Khalid Abdul Jabbar Wei Ting Seah Kenneth Kexun Chen Tze Pin Ng
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doi_str	10.1016/j.ahr.2022.100097
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up_date	2024-07-03T17:56:09.839Z
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However, it remains unclear whether increased adiposity or less lean mass is a stronger determinant of worse functional performance. This study compared the association between fat versus lean mass indices with physical function among community-dwelling adults after adjusting for age and muscle strength. Methods: 542 community-dwelling adults aged between 21 and 90 years were recruited. All participants were assessed for body composition (dual X-ray absorptiometry), knee extensor strength (KES) and physical function. Fat mass and lean mass (weight in kg) were adjusted by height (in meters) squared - measured as fat mass index (FMI) and appendicular lean mass index (ALMI), respectively. Physical function was assessed using the Short Physical Performance Battery (SPPB) and the timed up and go (TUG) test. Results: FMI was significantly associated with both SPPB (ß = -0.130, p = 0.019) and TUG (ß = 0.182, p < 0.01) after accounting for ALMI and other covariates. This association was moderated by age and KES. FMI was associated with SPPB and TUG in individuals who are older or with weaker KES. While ALMI was found to be significantly associated with TUG (ß = 0.121, p = 0.023), no significant association was found between ALMI and physical function after accounting for FMI. Conclusions: Our results show that FMI is a stronger determinant of physical function than ALMI. 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Association of fat mass index versus appendicular lean mass index with physical function – The Yishun Study

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