Synthesis of Methacrylate Monomers with Antibacterial Effects Against S. Mutans

A series of polymerizable quaternary ammonium compounds were synthesized with the aim of using them as immobilized antibacterial agents in methacrylate dental composites, and their structures were characterized by FT-IR, 1H-NMR, and 13C-NMR analysis. Their antibacterial activities against the oral b...
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Autor*in:	Jingwei He [verfasserIn] Monica Österblad [verfasserIn] Pekka K. Vallittu [verfasserIn] Lippo V. J. Lassila [verfasserIn] Eva Söderling [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2011

Schlagwörter:	dental materials methacrylate quaternary ammonium compounds antibacterial

Übergeordnetes Werk:	In: Molecules - MDPI AG, 2003, 16(2011), 11, Seite 9755-9763
Übergeordnetes Werk:	volume:16 ; year:2011 ; number:11 ; pages:9755-9763

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/molecules16119755

Katalog-ID:	DOAJ033536236

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520			\|a A series of polymerizable quaternary ammonium compounds were synthesized with the aim of using them as immobilized antibacterial agents in methacrylate dental composites, and their structures were characterized by FT-IR, 1H-NMR, and 13C-NMR analysis. Their antibacterial activities against the oral bacterium Streptococcus mutans were evaluated in vitro by a Minimum Inhibitory Concentration test, and the results showed that 2-dimethyl-2-hexadecyl-1-methacryloxyethyl ammonium iodide (C16) had the highest antibacterial activity against S. mutans, and 2-dimethyl-2-pentyl-1-methacryloxyethyl ammonium iodide (C5) and 2-dimethyl-2-octyl-1-methacryloxyethyl ammonium iodide (C8) did not show any inhibition.
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spelling	10.3390/molecules16119755 doi (DE-627)DOAJ033536236 (DE-599)DOAJ3212d707ee3b40baab63d456d95cf1f7 DE-627 ger DE-627 rakwb eng QD241-441 Jingwei He verfasserin aut Synthesis of Methacrylate Monomers with Antibacterial Effects Against S. Mutans 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A series of polymerizable quaternary ammonium compounds were synthesized with the aim of using them as immobilized antibacterial agents in methacrylate dental composites, and their structures were characterized by FT-IR, 1H-NMR, and 13C-NMR analysis. Their antibacterial activities against the oral bacterium Streptococcus mutans were evaluated in vitro by a Minimum Inhibitory Concentration test, and the results showed that 2-dimethyl-2-hexadecyl-1-methacryloxyethyl ammonium iodide (C16) had the highest antibacterial activity against S. mutans, and 2-dimethyl-2-pentyl-1-methacryloxyethyl ammonium iodide (C5) and 2-dimethyl-2-octyl-1-methacryloxyethyl ammonium iodide (C8) did not show any inhibition. dental materials methacrylate quaternary ammonium compounds antibacterial Organic chemistry Monica Österblad verfasserin aut Pekka K. Vallittu verfasserin aut Lippo V. J. Lassila verfasserin aut Eva Söderling verfasserin aut In Molecules MDPI AG, 2003 16(2011), 11, Seite 9755-9763 (DE-627)311313132 (DE-600)2008644-1 14203049 nnns volume:16 year:2011 number:11 pages:9755-9763 https://doi.org/10.3390/molecules16119755 kostenfrei https://doaj.org/article/3212d707ee3b40baab63d456d95cf1f7 kostenfrei http://www.mdpi.com/1420-3049/16/11/9755/ kostenfrei https://doaj.org/toc/1420-3049 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 16 2011 11 9755-9763
allfields_unstemmed	10.3390/molecules16119755 doi (DE-627)DOAJ033536236 (DE-599)DOAJ3212d707ee3b40baab63d456d95cf1f7 DE-627 ger DE-627 rakwb eng QD241-441 Jingwei He verfasserin aut Synthesis of Methacrylate Monomers with Antibacterial Effects Against S. Mutans 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A series of polymerizable quaternary ammonium compounds were synthesized with the aim of using them as immobilized antibacterial agents in methacrylate dental composites, and their structures were characterized by FT-IR, 1H-NMR, and 13C-NMR analysis. Their antibacterial activities against the oral bacterium Streptococcus mutans were evaluated in vitro by a Minimum Inhibitory Concentration test, and the results showed that 2-dimethyl-2-hexadecyl-1-methacryloxyethyl ammonium iodide (C16) had the highest antibacterial activity against S. mutans, and 2-dimethyl-2-pentyl-1-methacryloxyethyl ammonium iodide (C5) and 2-dimethyl-2-octyl-1-methacryloxyethyl ammonium iodide (C8) did not show any inhibition. dental materials methacrylate quaternary ammonium compounds antibacterial Organic chemistry Monica Österblad verfasserin aut Pekka K. Vallittu verfasserin aut Lippo V. J. Lassila verfasserin aut Eva Söderling verfasserin aut In Molecules MDPI AG, 2003 16(2011), 11, Seite 9755-9763 (DE-627)311313132 (DE-600)2008644-1 14203049 nnns volume:16 year:2011 number:11 pages:9755-9763 https://doi.org/10.3390/molecules16119755 kostenfrei https://doaj.org/article/3212d707ee3b40baab63d456d95cf1f7 kostenfrei http://www.mdpi.com/1420-3049/16/11/9755/ kostenfrei https://doaj.org/toc/1420-3049 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 16 2011 11 9755-9763
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language	English
source	In Molecules 16(2011), 11, Seite 9755-9763 volume:16 year:2011 number:11 pages:9755-9763
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topic_facet	dental materials methacrylate quaternary ammonium compounds antibacterial Organic chemistry
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authorswithroles_txt_mv	Jingwei He @@aut@@ Monica Österblad @@aut@@ Pekka K. Vallittu @@aut@@ Lippo V. J. Lassila @@aut@@ Eva Söderling @@aut@@
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callnumber-first	Q - Science
author	Jingwei He
spellingShingle	Jingwei He misc QD241-441 misc dental materials misc methacrylate misc quaternary ammonium compounds misc antibacterial misc Organic chemistry Synthesis of Methacrylate Monomers with Antibacterial Effects Against S. Mutans
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topic_title	QD241-441 Synthesis of Methacrylate Monomers with Antibacterial Effects Against S. Mutans dental materials methacrylate quaternary ammonium compounds antibacterial
topic	misc QD241-441 misc dental materials misc methacrylate misc quaternary ammonium compounds misc antibacterial misc Organic chemistry
topic_unstemmed	misc QD241-441 misc dental materials misc methacrylate misc quaternary ammonium compounds misc antibacterial misc Organic chemistry
topic_browse	misc QD241-441 misc dental materials misc methacrylate misc quaternary ammonium compounds misc antibacterial misc Organic chemistry
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title	Synthesis of Methacrylate Monomers with Antibacterial Effects Against S. Mutans
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title_full	Synthesis of Methacrylate Monomers with Antibacterial Effects Against S. Mutans
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title_sort	synthesis of methacrylate monomers with antibacterial effects against s. mutans
callnumber	QD241-441
title_auth	Synthesis of Methacrylate Monomers with Antibacterial Effects Against S. Mutans
abstract	A series of polymerizable quaternary ammonium compounds were synthesized with the aim of using them as immobilized antibacterial agents in methacrylate dental composites, and their structures were characterized by FT-IR, 1H-NMR, and 13C-NMR analysis. Their antibacterial activities against the oral bacterium Streptococcus mutans were evaluated in vitro by a Minimum Inhibitory Concentration test, and the results showed that 2-dimethyl-2-hexadecyl-1-methacryloxyethyl ammonium iodide (C16) had the highest antibacterial activity against S. mutans, and 2-dimethyl-2-pentyl-1-methacryloxyethyl ammonium iodide (C5) and 2-dimethyl-2-octyl-1-methacryloxyethyl ammonium iodide (C8) did not show any inhibition.
abstractGer	A series of polymerizable quaternary ammonium compounds were synthesized with the aim of using them as immobilized antibacterial agents in methacrylate dental composites, and their structures were characterized by FT-IR, 1H-NMR, and 13C-NMR analysis. Their antibacterial activities against the oral bacterium Streptococcus mutans were evaluated in vitro by a Minimum Inhibitory Concentration test, and the results showed that 2-dimethyl-2-hexadecyl-1-methacryloxyethyl ammonium iodide (C16) had the highest antibacterial activity against S. mutans, and 2-dimethyl-2-pentyl-1-methacryloxyethyl ammonium iodide (C5) and 2-dimethyl-2-octyl-1-methacryloxyethyl ammonium iodide (C8) did not show any inhibition.
abstract_unstemmed	A series of polymerizable quaternary ammonium compounds were synthesized with the aim of using them as immobilized antibacterial agents in methacrylate dental composites, and their structures were characterized by FT-IR, 1H-NMR, and 13C-NMR analysis. Their antibacterial activities against the oral bacterium Streptococcus mutans were evaluated in vitro by a Minimum Inhibitory Concentration test, and the results showed that 2-dimethyl-2-hexadecyl-1-methacryloxyethyl ammonium iodide (C16) had the highest antibacterial activity against S. mutans, and 2-dimethyl-2-pentyl-1-methacryloxyethyl ammonium iodide (C5) and 2-dimethyl-2-octyl-1-methacryloxyethyl ammonium iodide (C8) did not show any inhibition.
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title_short	Synthesis of Methacrylate Monomers with Antibacterial Effects Against S. Mutans
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up_date	2024-07-03T18:19:08.435Z
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