A Simple Measure to Assess Hyperinflation and Air Trapping: 1-Forced Expiratory Volume in Three Second / Forced Vital Capacity

Background: Several recent studies have suggested that 1 minus-forced expiratory volume expired in 3 seconds / forced vital capacity (1-FEV3/FVC) may be an indicator of distal airway obstruction and a promising measure to evaluate small airways dysfunction. Aims: To investigate the associations of 1...
Ausführliche Beschreibung

Gespeichert in:
Autor*in:

Sermin Börekçi [verfasserIn]

Tunçalp Demir [verfasserIn]

Aslı Görek Dilektaşlı [verfasserIn]

Melahat Uygun [verfasserIn]

Nurhayat Yıldırım [verfasserIn]

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2017

Schlagwörter:

with a mean age of 52.5±15.6 years. Mean FEV3/FVC and 1-FEV3/FVC were 87.05%

12.95%

respectively. The mean 1-FEV3/FVC was 4.9% in the FEV1/FVC ≥70% group (n=644) vs. 24.1% in the FEV1/FVC <70% group (n=466). A positive correlation was found between 1-FEV3/FVC and residual volume (r=0.70; p<0.0001)

functional residual capacity-pleth (r=0.61; p<0.0001)

and total lung capacity (r=0.47; p<0.0001). 1-FEV3/FVC was negatively correlated with forced expiratory flow25-75 (r=−0.84; p<0.0001). The upper limit of 95% confidence interval for 1-FEV3/FVC was 13.7%. 1-FEV3/FVC showed significant correlations with parameters of air trapping and hyperinflation measured by whole-body plethysmography. Importantly

these correlations were higher in study participants with FEV1/FVC <70% or FEV3/FVC < LLN compared to those with FEV1/FVC ≥70% or FEV3/FVC ≥ LLN

1-FEV3/FVC

hyperinflation

spirometry

Übergeordnetes Werk:

In: Balkan Medical Journal - Galenos Publishing House, 2017, 34(2017), 2, Seite 113-118

Übergeordnetes Werk:

volume:34 ; year:2017 ; number:2 ; pages:113-118

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DOI / URN:

10.4274/balkanmedj.2015.0857

Katalog-ID:

DOAJ033679541

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