Investigation of <i<Morinda citrifolia</i< Activities through Pinoresinol and α-EG Related Gene Expression

α-EG is a unique substance that was first found in the leaves and fruits of <i<Morinda citrifolia</i< (Mc) growing in Thailand using GC-MS at 52.33% and 54.12%. It was then concentrated and its abundance quantified, along with that of pinoresinol, via GC, compared to the standards in lea...
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Autor*in:	Runglawan Sudmoon [verfasserIn] Sanit Kaewdaungdee [verfasserIn] Unchaleeporn Ameamsri [verfasserIn] Tawatchai Tanee [verfasserIn] Pornnarong Siripiyasing [verfasserIn] Warin Wonok [verfasserIn] Arunrat Chaveerach [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022

Schlagwörter:	α-EG pinoresinol qRT-PCR

Übergeordnetes Werk:	In: Plants - MDPI AG, 2013, 11(2022), 15, p 1985
Übergeordnetes Werk:	volume:11 ; year:2022 ; number:15, p 1985

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/plants11151985

Katalog-ID:	DOAJ03455775X

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allfields	10.3390/plants11151985 doi (DE-627)DOAJ03455775X (DE-599)DOAJ022b571fa0734a9d89027865b6adf68d DE-627 ger DE-627 rakwb eng QK1-989 Runglawan Sudmoon verfasserin aut Investigation of <i<Morinda citrifolia</i< Activities through Pinoresinol and α-EG Related Gene Expression 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier α-EG is a unique substance that was first found in the leaves and fruits of <i<Morinda citrifolia</i< (Mc) growing in Thailand using GC-MS at 52.33% and 54.12%. It was then concentrated and its abundance quantified, along with that of pinoresinol, via GC, compared to the standards in leaves, ufp, rfp, rawfs, and seeds. α-EG and pinoresinol, which have collagen stimulating, skin whitening, and an inhibitory effect on wrinkle formation, were found in different concentrations and amounts. Three different concentrations of the five Mc part extracts were tested on <i<NHDF</i< for gene expression related to the aforementioned activities, <i<COL1A1</i<, <i<COL1A2</i<, and <i<COL3A1</i<, <i<FGF1</i< and <i<FGF7</i< by qRT-PCR. The results showed various expression levels, both stimulatory and inhibitory, with different concentrations of plant parts and genes. Similar results were revealed when the experiments were performed with <i<Morus alba</i< (Ma), which was found to contain 20.48 g protein p/100 g leaves at concentrations of 3.11 mg/mL. The studied Mc parts seem to have advantages based on the stated objectives, gene type and level of activity of each plant part. Rawfs and leaves supplemented with Ma samples were selected for toxicity tests with PBMCs. The lack of both cell and DNA toxicity from the rawfs indicated that they can be used safely. α-EG pinoresinol <i<Morinda citrifolia</i< <i<Morus alba</i< qRT-PCR <i<COL1A1</i< Botany Sanit Kaewdaungdee verfasserin aut Unchaleeporn Ameamsri verfasserin aut Tawatchai Tanee verfasserin aut Pornnarong Siripiyasing verfasserin aut Warin Wonok verfasserin aut Arunrat Chaveerach verfasserin aut In Plants MDPI AG, 2013 11(2022), 15, p 1985 (DE-627)737288345 (DE-600)2704341-1 22237747 nnns volume:11 year:2022 number:15, p 1985 https://doi.org/10.3390/plants11151985 kostenfrei https://doaj.org/article/022b571fa0734a9d89027865b6adf68d kostenfrei https://www.mdpi.com/2223-7747/11/15/1985 kostenfrei https://doaj.org/toc/2223-7747 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2022 15, p 1985
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allfields_unstemmed	10.3390/plants11151985 doi (DE-627)DOAJ03455775X (DE-599)DOAJ022b571fa0734a9d89027865b6adf68d DE-627 ger DE-627 rakwb eng QK1-989 Runglawan Sudmoon verfasserin aut Investigation of <i<Morinda citrifolia</i< Activities through Pinoresinol and α-EG Related Gene Expression 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier α-EG is a unique substance that was first found in the leaves and fruits of <i<Morinda citrifolia</i< (Mc) growing in Thailand using GC-MS at 52.33% and 54.12%. It was then concentrated and its abundance quantified, along with that of pinoresinol, via GC, compared to the standards in leaves, ufp, rfp, rawfs, and seeds. α-EG and pinoresinol, which have collagen stimulating, skin whitening, and an inhibitory effect on wrinkle formation, were found in different concentrations and amounts. Three different concentrations of the five Mc part extracts were tested on <i<NHDF</i< for gene expression related to the aforementioned activities, <i<COL1A1</i<, <i<COL1A2</i<, and <i<COL3A1</i<, <i<FGF1</i< and <i<FGF7</i< by qRT-PCR. The results showed various expression levels, both stimulatory and inhibitory, with different concentrations of plant parts and genes. Similar results were revealed when the experiments were performed with <i<Morus alba</i< (Ma), which was found to contain 20.48 g protein p/100 g leaves at concentrations of 3.11 mg/mL. The studied Mc parts seem to have advantages based on the stated objectives, gene type and level of activity of each plant part. Rawfs and leaves supplemented with Ma samples were selected for toxicity tests with PBMCs. The lack of both cell and DNA toxicity from the rawfs indicated that they can be used safely. α-EG pinoresinol <i<Morinda citrifolia</i< <i<Morus alba</i< qRT-PCR <i<COL1A1</i< Botany Sanit Kaewdaungdee verfasserin aut Unchaleeporn Ameamsri verfasserin aut Tawatchai Tanee verfasserin aut Pornnarong Siripiyasing verfasserin aut Warin Wonok verfasserin aut Arunrat Chaveerach verfasserin aut In Plants MDPI AG, 2013 11(2022), 15, p 1985 (DE-627)737288345 (DE-600)2704341-1 22237747 nnns volume:11 year:2022 number:15, p 1985 https://doi.org/10.3390/plants11151985 kostenfrei https://doaj.org/article/022b571fa0734a9d89027865b6adf68d kostenfrei https://www.mdpi.com/2223-7747/11/15/1985 kostenfrei https://doaj.org/toc/2223-7747 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2022 15, p 1985
allfieldsGer	10.3390/plants11151985 doi (DE-627)DOAJ03455775X (DE-599)DOAJ022b571fa0734a9d89027865b6adf68d DE-627 ger DE-627 rakwb eng QK1-989 Runglawan Sudmoon verfasserin aut Investigation of <i<Morinda citrifolia</i< Activities through Pinoresinol and α-EG Related Gene Expression 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier α-EG is a unique substance that was first found in the leaves and fruits of <i<Morinda citrifolia</i< (Mc) growing in Thailand using GC-MS at 52.33% and 54.12%. It was then concentrated and its abundance quantified, along with that of pinoresinol, via GC, compared to the standards in leaves, ufp, rfp, rawfs, and seeds. α-EG and pinoresinol, which have collagen stimulating, skin whitening, and an inhibitory effect on wrinkle formation, were found in different concentrations and amounts. Three different concentrations of the five Mc part extracts were tested on <i<NHDF</i< for gene expression related to the aforementioned activities, <i<COL1A1</i<, <i<COL1A2</i<, and <i<COL3A1</i<, <i<FGF1</i< and <i<FGF7</i< by qRT-PCR. The results showed various expression levels, both stimulatory and inhibitory, with different concentrations of plant parts and genes. Similar results were revealed when the experiments were performed with <i<Morus alba</i< (Ma), which was found to contain 20.48 g protein p/100 g leaves at concentrations of 3.11 mg/mL. The studied Mc parts seem to have advantages based on the stated objectives, gene type and level of activity of each plant part. Rawfs and leaves supplemented with Ma samples were selected for toxicity tests with PBMCs. The lack of both cell and DNA toxicity from the rawfs indicated that they can be used safely. α-EG pinoresinol <i<Morinda citrifolia</i< <i<Morus alba</i< qRT-PCR <i<COL1A1</i< Botany Sanit Kaewdaungdee verfasserin aut Unchaleeporn Ameamsri verfasserin aut Tawatchai Tanee verfasserin aut Pornnarong Siripiyasing verfasserin aut Warin Wonok verfasserin aut Arunrat Chaveerach verfasserin aut In Plants MDPI AG, 2013 11(2022), 15, p 1985 (DE-627)737288345 (DE-600)2704341-1 22237747 nnns volume:11 year:2022 number:15, p 1985 https://doi.org/10.3390/plants11151985 kostenfrei https://doaj.org/article/022b571fa0734a9d89027865b6adf68d kostenfrei https://www.mdpi.com/2223-7747/11/15/1985 kostenfrei https://doaj.org/toc/2223-7747 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2022 15, p 1985
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callnumber-first	Q - Science
author	Runglawan Sudmoon
spellingShingle	Runglawan Sudmoon misc QK1-989 misc α-EG misc pinoresinol misc <i<Morinda citrifolia</i< misc <i<Morus alba</i< misc qRT-PCR misc <i<COL1A1</i< misc Botany Investigation of <i<Morinda citrifolia</i< Activities through Pinoresinol and α-EG Related Gene Expression
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topic_title	QK1-989 Investigation of <i<Morinda citrifolia</i< Activities through Pinoresinol and α-EG Related Gene Expression α-EG pinoresinol <i<Morinda citrifolia</i< <i<Morus alba</i< qRT-PCR <i<COL1A1</i<
topic	misc QK1-989 misc α-EG misc pinoresinol misc <i<Morinda citrifolia</i< misc <i<Morus alba</i< misc qRT-PCR misc <i<COL1A1</i< misc Botany
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title	Investigation of <i<Morinda citrifolia</i< Activities through Pinoresinol and α-EG Related Gene Expression
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title_full	Investigation of <i<Morinda citrifolia</i< Activities through Pinoresinol and α-EG Related Gene Expression
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title_sort	investigation of <i<morinda citrifolia</i< activities through pinoresinol and α-eg related gene expression
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title_auth	Investigation of <i<Morinda citrifolia</i< Activities through Pinoresinol and α-EG Related Gene Expression
abstract	α-EG is a unique substance that was first found in the leaves and fruits of <i<Morinda citrifolia</i< (Mc) growing in Thailand using GC-MS at 52.33% and 54.12%. It was then concentrated and its abundance quantified, along with that of pinoresinol, via GC, compared to the standards in leaves, ufp, rfp, rawfs, and seeds. α-EG and pinoresinol, which have collagen stimulating, skin whitening, and an inhibitory effect on wrinkle formation, were found in different concentrations and amounts. Three different concentrations of the five Mc part extracts were tested on <i<NHDF</i< for gene expression related to the aforementioned activities, <i<COL1A1</i<, <i<COL1A2</i<, and <i<COL3A1</i<, <i<FGF1</i< and <i<FGF7</i< by qRT-PCR. The results showed various expression levels, both stimulatory and inhibitory, with different concentrations of plant parts and genes. Similar results were revealed when the experiments were performed with <i<Morus alba</i< (Ma), which was found to contain 20.48 g protein p/100 g leaves at concentrations of 3.11 mg/mL. The studied Mc parts seem to have advantages based on the stated objectives, gene type and level of activity of each plant part. Rawfs and leaves supplemented with Ma samples were selected for toxicity tests with PBMCs. The lack of both cell and DNA toxicity from the rawfs indicated that they can be used safely.
abstractGer	α-EG is a unique substance that was first found in the leaves and fruits of <i<Morinda citrifolia</i< (Mc) growing in Thailand using GC-MS at 52.33% and 54.12%. It was then concentrated and its abundance quantified, along with that of pinoresinol, via GC, compared to the standards in leaves, ufp, rfp, rawfs, and seeds. α-EG and pinoresinol, which have collagen stimulating, skin whitening, and an inhibitory effect on wrinkle formation, were found in different concentrations and amounts. Three different concentrations of the five Mc part extracts were tested on <i<NHDF</i< for gene expression related to the aforementioned activities, <i<COL1A1</i<, <i<COL1A2</i<, and <i<COL3A1</i<, <i<FGF1</i< and <i<FGF7</i< by qRT-PCR. The results showed various expression levels, both stimulatory and inhibitory, with different concentrations of plant parts and genes. Similar results were revealed when the experiments were performed with <i<Morus alba</i< (Ma), which was found to contain 20.48 g protein p/100 g leaves at concentrations of 3.11 mg/mL. The studied Mc parts seem to have advantages based on the stated objectives, gene type and level of activity of each plant part. Rawfs and leaves supplemented with Ma samples were selected for toxicity tests with PBMCs. The lack of both cell and DNA toxicity from the rawfs indicated that they can be used safely.
abstract_unstemmed	α-EG is a unique substance that was first found in the leaves and fruits of <i<Morinda citrifolia</i< (Mc) growing in Thailand using GC-MS at 52.33% and 54.12%. It was then concentrated and its abundance quantified, along with that of pinoresinol, via GC, compared to the standards in leaves, ufp, rfp, rawfs, and seeds. α-EG and pinoresinol, which have collagen stimulating, skin whitening, and an inhibitory effect on wrinkle formation, were found in different concentrations and amounts. Three different concentrations of the five Mc part extracts were tested on <i<NHDF</i< for gene expression related to the aforementioned activities, <i<COL1A1</i<, <i<COL1A2</i<, and <i<COL3A1</i<, <i<FGF1</i< and <i<FGF7</i< by qRT-PCR. The results showed various expression levels, both stimulatory and inhibitory, with different concentrations of plant parts and genes. Similar results were revealed when the experiments were performed with <i<Morus alba</i< (Ma), which was found to contain 20.48 g protein p/100 g leaves at concentrations of 3.11 mg/mL. The studied Mc parts seem to have advantages based on the stated objectives, gene type and level of activity of each plant part. Rawfs and leaves supplemented with Ma samples were selected for toxicity tests with PBMCs. The lack of both cell and DNA toxicity from the rawfs indicated that they can be used safely.
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container_issue	15, p 1985
title_short	Investigation of <i<Morinda citrifolia</i< Activities through Pinoresinol and α-EG Related Gene Expression
url	https://doi.org/10.3390/plants11151985 https://doaj.org/article/022b571fa0734a9d89027865b6adf68d https://www.mdpi.com/2223-7747/11/15/1985 https://doaj.org/toc/2223-7747
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The studied Mc parts seem to have advantages based on the stated objectives, gene type and level of activity of each plant part. Rawfs and leaves supplemented with Ma samples were selected for toxicity tests with PBMCs. 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Investigation of <i<Morinda citrifolia</i< Activities through Pinoresinol and α-EG Related Gene Expression

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