Action of a deproteinized xenogenic biomaterial in the process of bone repair in rats submitted to inhalation of cigarette smoke

Abstract Purpose: To investigate if the inorganic bovine bone matrix changes the bone formation in rats submitted to inhalation of cigarette smoke. Methods: Twenty Wistar rats were divided into two groups: Cigarette Clot Group (CCG), which in the inhalation chamber received the smoke of 10 cigar...
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Gespeichert in:

Autor*in:	Daniela Vieira Buchaim [verfasserIn] Patrícia Cincotto dos Santos Bueno [verfasserIn] Jesus Carlos Andreo [verfasserIn] Domingos Donizeti Roque [verfasserIn] José Sidney Roque [verfasserIn] Marcelo Garcia Zilio [verfasserIn] Jefferson Augusto Salatin [verfasserIn] Natália Kawano [verfasserIn] Gabriela Furlanette [verfasserIn] Rogério Leone Buchaim [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2018

Schlagwörter:	Biocompatible Materials Bone Regeneration Bone Transplantation Heterografts Smoking Rats.

Übergeordnetes Werk:	In: Acta Cirúrgica Brasileira - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2004, 33(2018), 4, Seite 324-332
Übergeordnetes Werk:	volume:33 ; year:2018 ; number:4 ; pages:324-332

Links:	Link aufrufen Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1590/s0102-865020180040000004

Katalog-ID:	DOAJ034790926

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520			\|a Abstract Purpose: To investigate if the inorganic bovine bone matrix changes the bone formation in rats submitted to inhalation of cigarette smoke. Methods: Twenty Wistar rats were divided into two groups: Cigarette Clot Group (CCG), which in the inhalation chamber received the smoke of 10 cigarettes, 3 times a day, 10 minutes, for 30 days and had the surgical cavity filled by clot; Cigarette Biomaterial Group (CBG), submitted to the same inhalation technique but with the cavity filled by biomaterial. Results: In CCG there was a significant difference of new bone tissue in the analyzed periods (15 and 45 days), and in 15 days, there was 4.8 ± 0.42 of bone formed and 11.73 ± 0.59 (p <0.05) in 45 days. The CBG also showed a significant difference between the periods of 15 to 45 days, being respectively 6.16 ± 0.30 and 11.60 ± 0.61. However, when the groups were compared, within the same analyzed periods, a significant difference was observed only in the period of 15 days, with the new bone percentage being greater in the CBG. Conclusion: The bone matrix acted as an osteoinductive biomaterial, biocompatible and aided in the repair process, mainly in the initial period of recovery.
650		4	\|a Biocompatible Materials
650		4	\|a Bone Regeneration
650		4	\|a Bone Transplantation
650		4	\|a Heterografts
650		4	\|a Smoking
650		4	\|a Rats.
653		0	\|a Surgery
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700	0		\|a Jesus Carlos Andreo \|e verfasserin \|4 aut
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700	0		\|a Natália Kawano \|e verfasserin \|4 aut
700	0		\|a Gabriela Furlanette \|e verfasserin \|4 aut
700	0		\|a Rogério Leone Buchaim \|e verfasserin \|4 aut
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spelling	10.1590/s0102-865020180040000004 doi (DE-627)DOAJ034790926 (DE-599)DOAJ04686367e8384ae6a254d22547341cfc DE-627 ger DE-627 rakwb eng RD1-811 Daniela Vieira Buchaim verfasserin aut Action of a deproteinized xenogenic biomaterial in the process of bone repair in rats submitted to inhalation of cigarette smoke 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Purpose: To investigate if the inorganic bovine bone matrix changes the bone formation in rats submitted to inhalation of cigarette smoke. Methods: Twenty Wistar rats were divided into two groups: Cigarette Clot Group (CCG), which in the inhalation chamber received the smoke of 10 cigarettes, 3 times a day, 10 minutes, for 30 days and had the surgical cavity filled by clot; Cigarette Biomaterial Group (CBG), submitted to the same inhalation technique but with the cavity filled by biomaterial. Results: In CCG there was a significant difference of new bone tissue in the analyzed periods (15 and 45 days), and in 15 days, there was 4.8 ± 0.42 of bone formed and 11.73 ± 0.59 (p <0.05) in 45 days. The CBG also showed a significant difference between the periods of 15 to 45 days, being respectively 6.16 ± 0.30 and 11.60 ± 0.61. However, when the groups were compared, within the same analyzed periods, a significant difference was observed only in the period of 15 days, with the new bone percentage being greater in the CBG. Conclusion: The bone matrix acted as an osteoinductive biomaterial, biocompatible and aided in the repair process, mainly in the initial period of recovery. Biocompatible Materials Bone Regeneration Bone Transplantation Heterografts Smoking Rats. Surgery Patrícia Cincotto dos Santos Bueno verfasserin aut Jesus Carlos Andreo verfasserin aut Domingos Donizeti Roque verfasserin aut José Sidney Roque verfasserin aut Marcelo Garcia Zilio verfasserin aut Jefferson Augusto Salatin verfasserin aut Natália Kawano verfasserin aut Gabriela Furlanette verfasserin aut Rogério Leone Buchaim verfasserin aut In Acta Cirúrgica Brasileira Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2004 33(2018), 4, Seite 324-332 (DE-627)320500519 (DE-600)2012156-8 16782674 nnns volume:33 year:2018 number:4 pages:324-332 https://doi.org/10.1590/s0102-865020180040000004 kostenfrei https://doaj.org/article/04686367e8384ae6a254d22547341cfc kostenfrei http://www.scielo.br/pdf/acb/v33n4/1678-2674-acb-33-04-00324.pdf kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502018000400324&tlng=en kostenfrei https://doaj.org/toc/0102-8650 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 33 2018 4 324-332
allfields_unstemmed	10.1590/s0102-865020180040000004 doi (DE-627)DOAJ034790926 (DE-599)DOAJ04686367e8384ae6a254d22547341cfc DE-627 ger DE-627 rakwb eng RD1-811 Daniela Vieira Buchaim verfasserin aut Action of a deproteinized xenogenic biomaterial in the process of bone repair in rats submitted to inhalation of cigarette smoke 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Purpose: To investigate if the inorganic bovine bone matrix changes the bone formation in rats submitted to inhalation of cigarette smoke. Methods: Twenty Wistar rats were divided into two groups: Cigarette Clot Group (CCG), which in the inhalation chamber received the smoke of 10 cigarettes, 3 times a day, 10 minutes, for 30 days and had the surgical cavity filled by clot; Cigarette Biomaterial Group (CBG), submitted to the same inhalation technique but with the cavity filled by biomaterial. Results: In CCG there was a significant difference of new bone tissue in the analyzed periods (15 and 45 days), and in 15 days, there was 4.8 ± 0.42 of bone formed and 11.73 ± 0.59 (p <0.05) in 45 days. The CBG also showed a significant difference between the periods of 15 to 45 days, being respectively 6.16 ± 0.30 and 11.60 ± 0.61. However, when the groups were compared, within the same analyzed periods, a significant difference was observed only in the period of 15 days, with the new bone percentage being greater in the CBG. Conclusion: The bone matrix acted as an osteoinductive biomaterial, biocompatible and aided in the repair process, mainly in the initial period of recovery. Biocompatible Materials Bone Regeneration Bone Transplantation Heterografts Smoking Rats. Surgery Patrícia Cincotto dos Santos Bueno verfasserin aut Jesus Carlos Andreo verfasserin aut Domingos Donizeti Roque verfasserin aut José Sidney Roque verfasserin aut Marcelo Garcia Zilio verfasserin aut Jefferson Augusto Salatin verfasserin aut Natália Kawano verfasserin aut Gabriela Furlanette verfasserin aut Rogério Leone Buchaim verfasserin aut In Acta Cirúrgica Brasileira Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2004 33(2018), 4, Seite 324-332 (DE-627)320500519 (DE-600)2012156-8 16782674 nnns volume:33 year:2018 number:4 pages:324-332 https://doi.org/10.1590/s0102-865020180040000004 kostenfrei https://doaj.org/article/04686367e8384ae6a254d22547341cfc kostenfrei http://www.scielo.br/pdf/acb/v33n4/1678-2674-acb-33-04-00324.pdf kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502018000400324&tlng=en kostenfrei https://doaj.org/toc/0102-8650 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 33 2018 4 324-332
allfieldsGer	10.1590/s0102-865020180040000004 doi (DE-627)DOAJ034790926 (DE-599)DOAJ04686367e8384ae6a254d22547341cfc DE-627 ger DE-627 rakwb eng RD1-811 Daniela Vieira Buchaim verfasserin aut Action of a deproteinized xenogenic biomaterial in the process of bone repair in rats submitted to inhalation of cigarette smoke 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Purpose: To investigate if the inorganic bovine bone matrix changes the bone formation in rats submitted to inhalation of cigarette smoke. Methods: Twenty Wistar rats were divided into two groups: Cigarette Clot Group (CCG), which in the inhalation chamber received the smoke of 10 cigarettes, 3 times a day, 10 minutes, for 30 days and had the surgical cavity filled by clot; Cigarette Biomaterial Group (CBG), submitted to the same inhalation technique but with the cavity filled by biomaterial. Results: In CCG there was a significant difference of new bone tissue in the analyzed periods (15 and 45 days), and in 15 days, there was 4.8 ± 0.42 of bone formed and 11.73 ± 0.59 (p <0.05) in 45 days. The CBG also showed a significant difference between the periods of 15 to 45 days, being respectively 6.16 ± 0.30 and 11.60 ± 0.61. However, when the groups were compared, within the same analyzed periods, a significant difference was observed only in the period of 15 days, with the new bone percentage being greater in the CBG. Conclusion: The bone matrix acted as an osteoinductive biomaterial, biocompatible and aided in the repair process, mainly in the initial period of recovery. Biocompatible Materials Bone Regeneration Bone Transplantation Heterografts Smoking Rats. Surgery Patrícia Cincotto dos Santos Bueno verfasserin aut Jesus Carlos Andreo verfasserin aut Domingos Donizeti Roque verfasserin aut José Sidney Roque verfasserin aut Marcelo Garcia Zilio verfasserin aut Jefferson Augusto Salatin verfasserin aut Natália Kawano verfasserin aut Gabriela Furlanette verfasserin aut Rogério Leone Buchaim verfasserin aut In Acta Cirúrgica Brasileira Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2004 33(2018), 4, Seite 324-332 (DE-627)320500519 (DE-600)2012156-8 16782674 nnns volume:33 year:2018 number:4 pages:324-332 https://doi.org/10.1590/s0102-865020180040000004 kostenfrei https://doaj.org/article/04686367e8384ae6a254d22547341cfc kostenfrei http://www.scielo.br/pdf/acb/v33n4/1678-2674-acb-33-04-00324.pdf kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502018000400324&tlng=en kostenfrei https://doaj.org/toc/0102-8650 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 33 2018 4 324-332
allfieldsSound	10.1590/s0102-865020180040000004 doi (DE-627)DOAJ034790926 (DE-599)DOAJ04686367e8384ae6a254d22547341cfc DE-627 ger DE-627 rakwb eng RD1-811 Daniela Vieira Buchaim verfasserin aut Action of a deproteinized xenogenic biomaterial in the process of bone repair in rats submitted to inhalation of cigarette smoke 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Purpose: To investigate if the inorganic bovine bone matrix changes the bone formation in rats submitted to inhalation of cigarette smoke. Methods: Twenty Wistar rats were divided into two groups: Cigarette Clot Group (CCG), which in the inhalation chamber received the smoke of 10 cigarettes, 3 times a day, 10 minutes, for 30 days and had the surgical cavity filled by clot; Cigarette Biomaterial Group (CBG), submitted to the same inhalation technique but with the cavity filled by biomaterial. Results: In CCG there was a significant difference of new bone tissue in the analyzed periods (15 and 45 days), and in 15 days, there was 4.8 ± 0.42 of bone formed and 11.73 ± 0.59 (p <0.05) in 45 days. The CBG also showed a significant difference between the periods of 15 to 45 days, being respectively 6.16 ± 0.30 and 11.60 ± 0.61. However, when the groups were compared, within the same analyzed periods, a significant difference was observed only in the period of 15 days, with the new bone percentage being greater in the CBG. Conclusion: The bone matrix acted as an osteoinductive biomaterial, biocompatible and aided in the repair process, mainly in the initial period of recovery. Biocompatible Materials Bone Regeneration Bone Transplantation Heterografts Smoking Rats. Surgery Patrícia Cincotto dos Santos Bueno verfasserin aut Jesus Carlos Andreo verfasserin aut Domingos Donizeti Roque verfasserin aut José Sidney Roque verfasserin aut Marcelo Garcia Zilio verfasserin aut Jefferson Augusto Salatin verfasserin aut Natália Kawano verfasserin aut Gabriela Furlanette verfasserin aut Rogério Leone Buchaim verfasserin aut In Acta Cirúrgica Brasileira Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2004 33(2018), 4, Seite 324-332 (DE-627)320500519 (DE-600)2012156-8 16782674 nnns volume:33 year:2018 number:4 pages:324-332 https://doi.org/10.1590/s0102-865020180040000004 kostenfrei https://doaj.org/article/04686367e8384ae6a254d22547341cfc kostenfrei http://www.scielo.br/pdf/acb/v33n4/1678-2674-acb-33-04-00324.pdf kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502018000400324&tlng=en kostenfrei https://doaj.org/toc/0102-8650 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 33 2018 4 324-332
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source	In Acta Cirúrgica Brasileira 33(2018), 4, Seite 324-332 volume:33 year:2018 number:4 pages:324-332
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topic_facet	Biocompatible Materials Bone Regeneration Bone Transplantation Heterografts Smoking Rats. Surgery
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authorswithroles_txt_mv	Daniela Vieira Buchaim @@aut@@ Patrícia Cincotto dos Santos Bueno @@aut@@ Jesus Carlos Andreo @@aut@@ Domingos Donizeti Roque @@aut@@ José Sidney Roque @@aut@@ Marcelo Garcia Zilio @@aut@@ Jefferson Augusto Salatin @@aut@@ Natália Kawano @@aut@@ Gabriela Furlanette @@aut@@ Rogério Leone Buchaim @@aut@@
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callnumber-first	R - Medicine
author	Daniela Vieira Buchaim
spellingShingle	Daniela Vieira Buchaim misc RD1-811 misc Biocompatible Materials misc Bone Regeneration misc Bone Transplantation misc Heterografts misc Smoking misc Rats. misc Surgery Action of a deproteinized xenogenic biomaterial in the process of bone repair in rats submitted to inhalation of cigarette smoke
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topic_title	RD1-811 Action of a deproteinized xenogenic biomaterial in the process of bone repair in rats submitted to inhalation of cigarette smoke Biocompatible Materials Bone Regeneration Bone Transplantation Heterografts Smoking Rats
topic	misc RD1-811 misc Biocompatible Materials misc Bone Regeneration misc Bone Transplantation misc Heterografts misc Smoking misc Rats. misc Surgery
topic_unstemmed	misc RD1-811 misc Biocompatible Materials misc Bone Regeneration misc Bone Transplantation misc Heterografts misc Smoking misc Rats. misc Surgery
topic_browse	misc RD1-811 misc Biocompatible Materials misc Bone Regeneration misc Bone Transplantation misc Heterografts misc Smoking misc Rats. misc Surgery
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title	Action of a deproteinized xenogenic biomaterial in the process of bone repair in rats submitted to inhalation of cigarette smoke
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title_full	Action of a deproteinized xenogenic biomaterial in the process of bone repair in rats submitted to inhalation of cigarette smoke
author_sort	Daniela Vieira Buchaim
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author_browse	Daniela Vieira Buchaim Patrícia Cincotto dos Santos Bueno Jesus Carlos Andreo Domingos Donizeti Roque José Sidney Roque Marcelo Garcia Zilio Jefferson Augusto Salatin Natália Kawano Gabriela Furlanette Rogério Leone Buchaim
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title_sort	action of a deproteinized xenogenic biomaterial in the process of bone repair in rats submitted to inhalation of cigarette smoke
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title_auth	Action of a deproteinized xenogenic biomaterial in the process of bone repair in rats submitted to inhalation of cigarette smoke
abstract	Abstract Purpose: To investigate if the inorganic bovine bone matrix changes the bone formation in rats submitted to inhalation of cigarette smoke. Methods: Twenty Wistar rats were divided into two groups: Cigarette Clot Group (CCG), which in the inhalation chamber received the smoke of 10 cigarettes, 3 times a day, 10 minutes, for 30 days and had the surgical cavity filled by clot; Cigarette Biomaterial Group (CBG), submitted to the same inhalation technique but with the cavity filled by biomaterial. Results: In CCG there was a significant difference of new bone tissue in the analyzed periods (15 and 45 days), and in 15 days, there was 4.8 ± 0.42 of bone formed and 11.73 ± 0.59 (p <0.05) in 45 days. The CBG also showed a significant difference between the periods of 15 to 45 days, being respectively 6.16 ± 0.30 and 11.60 ± 0.61. However, when the groups were compared, within the same analyzed periods, a significant difference was observed only in the period of 15 days, with the new bone percentage being greater in the CBG. Conclusion: The bone matrix acted as an osteoinductive biomaterial, biocompatible and aided in the repair process, mainly in the initial period of recovery.
abstractGer	Abstract Purpose: To investigate if the inorganic bovine bone matrix changes the bone formation in rats submitted to inhalation of cigarette smoke. Methods: Twenty Wistar rats were divided into two groups: Cigarette Clot Group (CCG), which in the inhalation chamber received the smoke of 10 cigarettes, 3 times a day, 10 minutes, for 30 days and had the surgical cavity filled by clot; Cigarette Biomaterial Group (CBG), submitted to the same inhalation technique but with the cavity filled by biomaterial. Results: In CCG there was a significant difference of new bone tissue in the analyzed periods (15 and 45 days), and in 15 days, there was 4.8 ± 0.42 of bone formed and 11.73 ± 0.59 (p <0.05) in 45 days. The CBG also showed a significant difference between the periods of 15 to 45 days, being respectively 6.16 ± 0.30 and 11.60 ± 0.61. However, when the groups were compared, within the same analyzed periods, a significant difference was observed only in the period of 15 days, with the new bone percentage being greater in the CBG. Conclusion: The bone matrix acted as an osteoinductive biomaterial, biocompatible and aided in the repair process, mainly in the initial period of recovery.
abstract_unstemmed	Abstract Purpose: To investigate if the inorganic bovine bone matrix changes the bone formation in rats submitted to inhalation of cigarette smoke. Methods: Twenty Wistar rats were divided into two groups: Cigarette Clot Group (CCG), which in the inhalation chamber received the smoke of 10 cigarettes, 3 times a day, 10 minutes, for 30 days and had the surgical cavity filled by clot; Cigarette Biomaterial Group (CBG), submitted to the same inhalation technique but with the cavity filled by biomaterial. Results: In CCG there was a significant difference of new bone tissue in the analyzed periods (15 and 45 days), and in 15 days, there was 4.8 ± 0.42 of bone formed and 11.73 ± 0.59 (p <0.05) in 45 days. The CBG also showed a significant difference between the periods of 15 to 45 days, being respectively 6.16 ± 0.30 and 11.60 ± 0.61. However, when the groups were compared, within the same analyzed periods, a significant difference was observed only in the period of 15 days, with the new bone percentage being greater in the CBG. Conclusion: The bone matrix acted as an osteoinductive biomaterial, biocompatible and aided in the repair process, mainly in the initial period of recovery.
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title_short	Action of a deproteinized xenogenic biomaterial in the process of bone repair in rats submitted to inhalation of cigarette smoke
url	https://doi.org/10.1590/s0102-865020180040000004 https://doaj.org/article/04686367e8384ae6a254d22547341cfc http://www.scielo.br/pdf/acb/v33n4/1678-2674-acb-33-04-00324.pdf http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502018000400324&tlng=en https://doaj.org/toc/0102-8650
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author2	Patrícia Cincotto dos Santos Bueno Jesus Carlos Andreo Domingos Donizeti Roque José Sidney Roque Marcelo Garcia Zilio Jefferson Augusto Salatin Natália Kawano Gabriela Furlanette Rogério Leone Buchaim
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Methods: Twenty Wistar rats were divided into two groups: Cigarette Clot Group (CCG), which in the inhalation chamber received the smoke of 10 cigarettes, 3 times a day, 10 minutes, for 30 days and had the surgical cavity filled by clot; Cigarette Biomaterial Group (CBG), submitted to the same inhalation technique but with the cavity filled by biomaterial. Results: In CCG there was a significant difference of new bone tissue in the analyzed periods (15 and 45 days), and in 15 days, there was 4.8 ± 0.42 of bone formed and 11.73 ± 0.59 (p <0.05) in 45 days. The CBG also showed a significant difference between the periods of 15 to 45 days, being respectively 6.16 ± 0.30 and 11.60 ± 0.61. However, when the groups were compared, within the same analyzed periods, a significant difference was observed only in the period of 15 days, with the new bone percentage being greater in the CBG. 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Action of a deproteinized xenogenic biomaterial in the process of bone repair in rats submitted to inhalation of cigarette smoke

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