DETECTION OF MARKERS OF HERPES VIRUS INFECTION AND PNEUMOCYSTOSIS IN CHILDREN FROM HIV-INFECTED MOTHERS
Aim. Study the role of herpes viruses and pneumocystis in infectious complications in children from HIV-infected mothers. Materials and methods. Sera and blood cells from 59 children from HIV-infected mothers were studied for the presence of various markers of herpes virus infections and pneumocysto...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
P. A. Savinkov [verfasserIn] T. N. Rybalkina [verfasserIn] N. V. Karazhas [verfasserIn] R. E. Boshyan [verfasserIn] M. Yu. Kalugina [verfasserIn] M. N. Kornienko [verfasserIn] E. V. Rusakova [verfasserIn] E. M. Burmistrov [verfasserIn] I. A. Soldatova [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Russisch |
| Erschienen: |
2017 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
In: Журнал микробиологии, эпидемиологии и иммунобиологии - Central Research Institute for Epidemiology, 2020, (2017), 4, Seite 67-74 |
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| Übergeordnetes Werk: |
year:2017 ; number:4 ; pages:67-74 |
| Links: |
Link aufrufen |
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| DOI / URN: |
10.36233/0372-9311-2017-4-67-74 |
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| Katalog-ID: |
DOAJ035157682 |
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| 520 | |a Aim. Study the role of herpes viruses and pneumocystis in infectious complications in children from HIV-infected mothers. Materials and methods. Sera and blood cells from 59 children from HIV-infected mothers were studied for the presence of various markers of herpes virus infections and pneumocystosis by a complex of methods of modem laboratory diagnostics. Results. Frequency of detection of markers of herpes virus infection was from 10% for chicken pox in children with non-final HIV test to 93% for herpes simplex virus in HIV-infected children from closed organized groups. Signs of active infection in children with laboratory confirmed HIV infection were diagnosed 2.5 times more frequently for HSV infection and chicken pox and 1.8 times more frequently for HHV-6 and pneumocystis than in children with non-final HIV test. Markers of various disease stages with opportunistic infections (01) were detected in children with confirmed HIV-infection: primary acute and latent forms of the infection, reactivation, reconvalescence, whereas in children with non-final HIV test maternal antibodies against herpes virus and pneumocystis predominated. Markers of active infections excluding HSV and HHV-6 were more frequently detected in children from families than in children from closed organized groups. Conclusion. The feature detected - a lower percentage of detection of markers of active forms of 01 in HI V-infected children from social institutions - is determined by the fact that observation of these children is carried out by medical personnel that have the knowledge and experience of prophylaxis of infectious complications in HIV-infected children, whereas quality anti-epidemic regimen is frequently not maintained regarding home children with HIV infection. Another factor facilitating spread of opportunistic infections is the asocial lifestyle of most of the examined families. These data dictate the necessity of enhancement of anti-epidemic regimen and prophylaxis of opportunistic infections in family loci. Not only HIV-infected children, but also all the family members should be examined for markers of herpes virus infection and pneumocystosis in order to detect sources of the infection and timely execution of the prophylaxis measures. | ||
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10.36233/0372-9311-2017-4-67-74 doi (DE-627)DOAJ035157682 (DE-599)DOAJ12f9755b32704c55a14a88b46dce60ea DE-627 ger DE-627 rakwb rus QR1-502 P. A. Savinkov verfasserin aut DETECTION OF MARKERS OF HERPES VIRUS INFECTION AND PNEUMOCYSTOSIS IN CHILDREN FROM HIV-INFECTED MOTHERS 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim. Study the role of herpes viruses and pneumocystis in infectious complications in children from HIV-infected mothers. Materials and methods. Sera and blood cells from 59 children from HIV-infected mothers were studied for the presence of various markers of herpes virus infections and pneumocystosis by a complex of methods of modem laboratory diagnostics. Results. Frequency of detection of markers of herpes virus infection was from 10% for chicken pox in children with non-final HIV test to 93% for herpes simplex virus in HIV-infected children from closed organized groups. Signs of active infection in children with laboratory confirmed HIV infection were diagnosed 2.5 times more frequently for HSV infection and chicken pox and 1.8 times more frequently for HHV-6 and pneumocystis than in children with non-final HIV test. Markers of various disease stages with opportunistic infections (01) were detected in children with confirmed HIV-infection: primary acute and latent forms of the infection, reactivation, reconvalescence, whereas in children with non-final HIV test maternal antibodies against herpes virus and pneumocystis predominated. Markers of active infections excluding HSV and HHV-6 were more frequently detected in children from families than in children from closed organized groups. Conclusion. The feature detected - a lower percentage of detection of markers of active forms of 01 in HI V-infected children from social institutions - is determined by the fact that observation of these children is carried out by medical personnel that have the knowledge and experience of prophylaxis of infectious complications in HIV-infected children, whereas quality anti-epidemic regimen is frequently not maintained regarding home children with HIV infection. Another factor facilitating spread of opportunistic infections is the asocial lifestyle of most of the examined families. These data dictate the necessity of enhancement of anti-epidemic regimen and prophylaxis of opportunistic infections in family loci. Not only HIV-infected children, but also all the family members should be examined for markers of herpes virus infection and pneumocystosis in order to detect sources of the infection and timely execution of the prophylaxis measures. hiv-infection opportunistic infections herpes virus infections pneumocystosis markers of active and acute infection infection reactivation Microbiology T. N. Rybalkina verfasserin aut N. V. Karazhas verfasserin aut R. E. Boshyan verfasserin aut M. Yu. Kalugina verfasserin aut M. N. Kornienko verfasserin aut E. V. Rusakova verfasserin aut E. M. Burmistrov verfasserin aut I. A. Soldatova verfasserin aut In Журнал микробиологии, эпидемиологии и иммунобиологии Central Research Institute for Epidemiology, 2020 (2017), 4, Seite 67-74 (DE-627)1760649171 26867613 nnns year:2017 number:4 pages:67-74 https://doi.org/10.36233/0372-9311-2017-4-67-74 kostenfrei https://doaj.org/article/12f9755b32704c55a14a88b46dce60ea kostenfrei https://microbiol.elpub.ru/jour/article/view/181 kostenfrei https://doaj.org/toc/0372-9311 Journal toc kostenfrei https://doaj.org/toc/2686-7613 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 2017 4 67-74 |
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10.36233/0372-9311-2017-4-67-74 doi (DE-627)DOAJ035157682 (DE-599)DOAJ12f9755b32704c55a14a88b46dce60ea DE-627 ger DE-627 rakwb rus QR1-502 P. A. Savinkov verfasserin aut DETECTION OF MARKERS OF HERPES VIRUS INFECTION AND PNEUMOCYSTOSIS IN CHILDREN FROM HIV-INFECTED MOTHERS 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim. Study the role of herpes viruses and pneumocystis in infectious complications in children from HIV-infected mothers. Materials and methods. Sera and blood cells from 59 children from HIV-infected mothers were studied for the presence of various markers of herpes virus infections and pneumocystosis by a complex of methods of modem laboratory diagnostics. Results. Frequency of detection of markers of herpes virus infection was from 10% for chicken pox in children with non-final HIV test to 93% for herpes simplex virus in HIV-infected children from closed organized groups. Signs of active infection in children with laboratory confirmed HIV infection were diagnosed 2.5 times more frequently for HSV infection and chicken pox and 1.8 times more frequently for HHV-6 and pneumocystis than in children with non-final HIV test. Markers of various disease stages with opportunistic infections (01) were detected in children with confirmed HIV-infection: primary acute and latent forms of the infection, reactivation, reconvalescence, whereas in children with non-final HIV test maternal antibodies against herpes virus and pneumocystis predominated. Markers of active infections excluding HSV and HHV-6 were more frequently detected in children from families than in children from closed organized groups. Conclusion. The feature detected - a lower percentage of detection of markers of active forms of 01 in HI V-infected children from social institutions - is determined by the fact that observation of these children is carried out by medical personnel that have the knowledge and experience of prophylaxis of infectious complications in HIV-infected children, whereas quality anti-epidemic regimen is frequently not maintained regarding home children with HIV infection. Another factor facilitating spread of opportunistic infections is the asocial lifestyle of most of the examined families. These data dictate the necessity of enhancement of anti-epidemic regimen and prophylaxis of opportunistic infections in family loci. Not only HIV-infected children, but also all the family members should be examined for markers of herpes virus infection and pneumocystosis in order to detect sources of the infection and timely execution of the prophylaxis measures. hiv-infection opportunistic infections herpes virus infections pneumocystosis markers of active and acute infection infection reactivation Microbiology T. N. Rybalkina verfasserin aut N. V. Karazhas verfasserin aut R. E. Boshyan verfasserin aut M. Yu. Kalugina verfasserin aut M. N. Kornienko verfasserin aut E. V. Rusakova verfasserin aut E. M. Burmistrov verfasserin aut I. A. Soldatova verfasserin aut In Журнал микробиологии, эпидемиологии и иммунобиологии Central Research Institute for Epidemiology, 2020 (2017), 4, Seite 67-74 (DE-627)1760649171 26867613 nnns year:2017 number:4 pages:67-74 https://doi.org/10.36233/0372-9311-2017-4-67-74 kostenfrei https://doaj.org/article/12f9755b32704c55a14a88b46dce60ea kostenfrei https://microbiol.elpub.ru/jour/article/view/181 kostenfrei https://doaj.org/toc/0372-9311 Journal toc kostenfrei https://doaj.org/toc/2686-7613 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 2017 4 67-74 |
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10.36233/0372-9311-2017-4-67-74 doi (DE-627)DOAJ035157682 (DE-599)DOAJ12f9755b32704c55a14a88b46dce60ea DE-627 ger DE-627 rakwb rus QR1-502 P. A. Savinkov verfasserin aut DETECTION OF MARKERS OF HERPES VIRUS INFECTION AND PNEUMOCYSTOSIS IN CHILDREN FROM HIV-INFECTED MOTHERS 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim. Study the role of herpes viruses and pneumocystis in infectious complications in children from HIV-infected mothers. Materials and methods. Sera and blood cells from 59 children from HIV-infected mothers were studied for the presence of various markers of herpes virus infections and pneumocystosis by a complex of methods of modem laboratory diagnostics. Results. Frequency of detection of markers of herpes virus infection was from 10% for chicken pox in children with non-final HIV test to 93% for herpes simplex virus in HIV-infected children from closed organized groups. Signs of active infection in children with laboratory confirmed HIV infection were diagnosed 2.5 times more frequently for HSV infection and chicken pox and 1.8 times more frequently for HHV-6 and pneumocystis than in children with non-final HIV test. Markers of various disease stages with opportunistic infections (01) were detected in children with confirmed HIV-infection: primary acute and latent forms of the infection, reactivation, reconvalescence, whereas in children with non-final HIV test maternal antibodies against herpes virus and pneumocystis predominated. Markers of active infections excluding HSV and HHV-6 were more frequently detected in children from families than in children from closed organized groups. Conclusion. The feature detected - a lower percentage of detection of markers of active forms of 01 in HI V-infected children from social institutions - is determined by the fact that observation of these children is carried out by medical personnel that have the knowledge and experience of prophylaxis of infectious complications in HIV-infected children, whereas quality anti-epidemic regimen is frequently not maintained regarding home children with HIV infection. Another factor facilitating spread of opportunistic infections is the asocial lifestyle of most of the examined families. These data dictate the necessity of enhancement of anti-epidemic regimen and prophylaxis of opportunistic infections in family loci. Not only HIV-infected children, but also all the family members should be examined for markers of herpes virus infection and pneumocystosis in order to detect sources of the infection and timely execution of the prophylaxis measures. hiv-infection opportunistic infections herpes virus infections pneumocystosis markers of active and acute infection infection reactivation Microbiology T. N. Rybalkina verfasserin aut N. V. Karazhas verfasserin aut R. E. Boshyan verfasserin aut M. Yu. Kalugina verfasserin aut M. N. Kornienko verfasserin aut E. V. Rusakova verfasserin aut E. M. Burmistrov verfasserin aut I. A. Soldatova verfasserin aut In Журнал микробиологии, эпидемиологии и иммунобиологии Central Research Institute for Epidemiology, 2020 (2017), 4, Seite 67-74 (DE-627)1760649171 26867613 nnns year:2017 number:4 pages:67-74 https://doi.org/10.36233/0372-9311-2017-4-67-74 kostenfrei https://doaj.org/article/12f9755b32704c55a14a88b46dce60ea kostenfrei https://microbiol.elpub.ru/jour/article/view/181 kostenfrei https://doaj.org/toc/0372-9311 Journal toc kostenfrei https://doaj.org/toc/2686-7613 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 2017 4 67-74 |
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10.36233/0372-9311-2017-4-67-74 doi (DE-627)DOAJ035157682 (DE-599)DOAJ12f9755b32704c55a14a88b46dce60ea DE-627 ger DE-627 rakwb rus QR1-502 P. A. Savinkov verfasserin aut DETECTION OF MARKERS OF HERPES VIRUS INFECTION AND PNEUMOCYSTOSIS IN CHILDREN FROM HIV-INFECTED MOTHERS 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim. Study the role of herpes viruses and pneumocystis in infectious complications in children from HIV-infected mothers. Materials and methods. Sera and blood cells from 59 children from HIV-infected mothers were studied for the presence of various markers of herpes virus infections and pneumocystosis by a complex of methods of modem laboratory diagnostics. Results. Frequency of detection of markers of herpes virus infection was from 10% for chicken pox in children with non-final HIV test to 93% for herpes simplex virus in HIV-infected children from closed organized groups. Signs of active infection in children with laboratory confirmed HIV infection were diagnosed 2.5 times more frequently for HSV infection and chicken pox and 1.8 times more frequently for HHV-6 and pneumocystis than in children with non-final HIV test. Markers of various disease stages with opportunistic infections (01) were detected in children with confirmed HIV-infection: primary acute and latent forms of the infection, reactivation, reconvalescence, whereas in children with non-final HIV test maternal antibodies against herpes virus and pneumocystis predominated. Markers of active infections excluding HSV and HHV-6 were more frequently detected in children from families than in children from closed organized groups. Conclusion. The feature detected - a lower percentage of detection of markers of active forms of 01 in HI V-infected children from social institutions - is determined by the fact that observation of these children is carried out by medical personnel that have the knowledge and experience of prophylaxis of infectious complications in HIV-infected children, whereas quality anti-epidemic regimen is frequently not maintained regarding home children with HIV infection. Another factor facilitating spread of opportunistic infections is the asocial lifestyle of most of the examined families. These data dictate the necessity of enhancement of anti-epidemic regimen and prophylaxis of opportunistic infections in family loci. Not only HIV-infected children, but also all the family members should be examined for markers of herpes virus infection and pneumocystosis in order to detect sources of the infection and timely execution of the prophylaxis measures. hiv-infection opportunistic infections herpes virus infections pneumocystosis markers of active and acute infection infection reactivation Microbiology T. N. Rybalkina verfasserin aut N. V. Karazhas verfasserin aut R. E. Boshyan verfasserin aut M. Yu. Kalugina verfasserin aut M. N. Kornienko verfasserin aut E. V. Rusakova verfasserin aut E. M. Burmistrov verfasserin aut I. A. Soldatova verfasserin aut In Журнал микробиологии, эпидемиологии и иммунобиологии Central Research Institute for Epidemiology, 2020 (2017), 4, Seite 67-74 (DE-627)1760649171 26867613 nnns year:2017 number:4 pages:67-74 https://doi.org/10.36233/0372-9311-2017-4-67-74 kostenfrei https://doaj.org/article/12f9755b32704c55a14a88b46dce60ea kostenfrei https://microbiol.elpub.ru/jour/article/view/181 kostenfrei https://doaj.org/toc/0372-9311 Journal toc kostenfrei https://doaj.org/toc/2686-7613 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 2017 4 67-74 |
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10.36233/0372-9311-2017-4-67-74 doi (DE-627)DOAJ035157682 (DE-599)DOAJ12f9755b32704c55a14a88b46dce60ea DE-627 ger DE-627 rakwb rus QR1-502 P. A. Savinkov verfasserin aut DETECTION OF MARKERS OF HERPES VIRUS INFECTION AND PNEUMOCYSTOSIS IN CHILDREN FROM HIV-INFECTED MOTHERS 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim. Study the role of herpes viruses and pneumocystis in infectious complications in children from HIV-infected mothers. Materials and methods. Sera and blood cells from 59 children from HIV-infected mothers were studied for the presence of various markers of herpes virus infections and pneumocystosis by a complex of methods of modem laboratory diagnostics. Results. Frequency of detection of markers of herpes virus infection was from 10% for chicken pox in children with non-final HIV test to 93% for herpes simplex virus in HIV-infected children from closed organized groups. Signs of active infection in children with laboratory confirmed HIV infection were diagnosed 2.5 times more frequently for HSV infection and chicken pox and 1.8 times more frequently for HHV-6 and pneumocystis than in children with non-final HIV test. Markers of various disease stages with opportunistic infections (01) were detected in children with confirmed HIV-infection: primary acute and latent forms of the infection, reactivation, reconvalescence, whereas in children with non-final HIV test maternal antibodies against herpes virus and pneumocystis predominated. Markers of active infections excluding HSV and HHV-6 were more frequently detected in children from families than in children from closed organized groups. Conclusion. The feature detected - a lower percentage of detection of markers of active forms of 01 in HI V-infected children from social institutions - is determined by the fact that observation of these children is carried out by medical personnel that have the knowledge and experience of prophylaxis of infectious complications in HIV-infected children, whereas quality anti-epidemic regimen is frequently not maintained regarding home children with HIV infection. Another factor facilitating spread of opportunistic infections is the asocial lifestyle of most of the examined families. These data dictate the necessity of enhancement of anti-epidemic regimen and prophylaxis of opportunistic infections in family loci. Not only HIV-infected children, but also all the family members should be examined for markers of herpes virus infection and pneumocystosis in order to detect sources of the infection and timely execution of the prophylaxis measures. hiv-infection opportunistic infections herpes virus infections pneumocystosis markers of active and acute infection infection reactivation Microbiology T. N. Rybalkina verfasserin aut N. V. Karazhas verfasserin aut R. E. Boshyan verfasserin aut M. Yu. Kalugina verfasserin aut M. N. Kornienko verfasserin aut E. V. Rusakova verfasserin aut E. M. Burmistrov verfasserin aut I. A. Soldatova verfasserin aut In Журнал микробиологии, эпидемиологии и иммунобиологии Central Research Institute for Epidemiology, 2020 (2017), 4, Seite 67-74 (DE-627)1760649171 26867613 nnns year:2017 number:4 pages:67-74 https://doi.org/10.36233/0372-9311-2017-4-67-74 kostenfrei https://doaj.org/article/12f9755b32704c55a14a88b46dce60ea kostenfrei https://microbiol.elpub.ru/jour/article/view/181 kostenfrei https://doaj.org/toc/0372-9311 Journal toc kostenfrei https://doaj.org/toc/2686-7613 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 2017 4 67-74 |
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Study the role of herpes viruses and pneumocystis in infectious complications in children from HIV-infected mothers. Materials and methods. Sera and blood cells from 59 children from HIV-infected mothers were studied for the presence of various markers of herpes virus infections and pneumocystosis by a complex of methods of modem laboratory diagnostics. Results. Frequency of detection of markers of herpes virus infection was from 10% for chicken pox in children with non-final HIV test to 93% for herpes simplex virus in HIV-infected children from closed organized groups. Signs of active infection in children with laboratory confirmed HIV infection were diagnosed 2.5 times more frequently for HSV infection and chicken pox and 1.8 times more frequently for HHV-6 and pneumocystis than in children with non-final HIV test. 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QR1-502 DETECTION OF MARKERS OF HERPES VIRUS INFECTION AND PNEUMOCYSTOSIS IN CHILDREN FROM HIV-INFECTED MOTHERS hiv-infection opportunistic infections herpes virus infections pneumocystosis markers of active and acute infection infection reactivation |
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P. A. Savinkov T. N. Rybalkina N. V. Karazhas R. E. Boshyan M. Yu. Kalugina M. N. Kornienko E. V. Rusakova E. M. Burmistrov I. A. Soldatova |
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detection of markers of herpes virus infection and pneumocystosis in children from hiv-infected mothers |
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DETECTION OF MARKERS OF HERPES VIRUS INFECTION AND PNEUMOCYSTOSIS IN CHILDREN FROM HIV-INFECTED MOTHERS |
| abstract |
Aim. Study the role of herpes viruses and pneumocystis in infectious complications in children from HIV-infected mothers. Materials and methods. Sera and blood cells from 59 children from HIV-infected mothers were studied for the presence of various markers of herpes virus infections and pneumocystosis by a complex of methods of modem laboratory diagnostics. Results. Frequency of detection of markers of herpes virus infection was from 10% for chicken pox in children with non-final HIV test to 93% for herpes simplex virus in HIV-infected children from closed organized groups. Signs of active infection in children with laboratory confirmed HIV infection were diagnosed 2.5 times more frequently for HSV infection and chicken pox and 1.8 times more frequently for HHV-6 and pneumocystis than in children with non-final HIV test. Markers of various disease stages with opportunistic infections (01) were detected in children with confirmed HIV-infection: primary acute and latent forms of the infection, reactivation, reconvalescence, whereas in children with non-final HIV test maternal antibodies against herpes virus and pneumocystis predominated. Markers of active infections excluding HSV and HHV-6 were more frequently detected in children from families than in children from closed organized groups. Conclusion. The feature detected - a lower percentage of detection of markers of active forms of 01 in HI V-infected children from social institutions - is determined by the fact that observation of these children is carried out by medical personnel that have the knowledge and experience of prophylaxis of infectious complications in HIV-infected children, whereas quality anti-epidemic regimen is frequently not maintained regarding home children with HIV infection. Another factor facilitating spread of opportunistic infections is the asocial lifestyle of most of the examined families. These data dictate the necessity of enhancement of anti-epidemic regimen and prophylaxis of opportunistic infections in family loci. Not only HIV-infected children, but also all the family members should be examined for markers of herpes virus infection and pneumocystosis in order to detect sources of the infection and timely execution of the prophylaxis measures. |
| abstractGer |
Aim. Study the role of herpes viruses and pneumocystis in infectious complications in children from HIV-infected mothers. Materials and methods. Sera and blood cells from 59 children from HIV-infected mothers were studied for the presence of various markers of herpes virus infections and pneumocystosis by a complex of methods of modem laboratory diagnostics. Results. Frequency of detection of markers of herpes virus infection was from 10% for chicken pox in children with non-final HIV test to 93% for herpes simplex virus in HIV-infected children from closed organized groups. Signs of active infection in children with laboratory confirmed HIV infection were diagnosed 2.5 times more frequently for HSV infection and chicken pox and 1.8 times more frequently for HHV-6 and pneumocystis than in children with non-final HIV test. Markers of various disease stages with opportunistic infections (01) were detected in children with confirmed HIV-infection: primary acute and latent forms of the infection, reactivation, reconvalescence, whereas in children with non-final HIV test maternal antibodies against herpes virus and pneumocystis predominated. Markers of active infections excluding HSV and HHV-6 were more frequently detected in children from families than in children from closed organized groups. Conclusion. The feature detected - a lower percentage of detection of markers of active forms of 01 in HI V-infected children from social institutions - is determined by the fact that observation of these children is carried out by medical personnel that have the knowledge and experience of prophylaxis of infectious complications in HIV-infected children, whereas quality anti-epidemic regimen is frequently not maintained regarding home children with HIV infection. Another factor facilitating spread of opportunistic infections is the asocial lifestyle of most of the examined families. These data dictate the necessity of enhancement of anti-epidemic regimen and prophylaxis of opportunistic infections in family loci. Not only HIV-infected children, but also all the family members should be examined for markers of herpes virus infection and pneumocystosis in order to detect sources of the infection and timely execution of the prophylaxis measures. |
| abstract_unstemmed |
Aim. Study the role of herpes viruses and pneumocystis in infectious complications in children from HIV-infected mothers. Materials and methods. Sera and blood cells from 59 children from HIV-infected mothers were studied for the presence of various markers of herpes virus infections and pneumocystosis by a complex of methods of modem laboratory diagnostics. Results. Frequency of detection of markers of herpes virus infection was from 10% for chicken pox in children with non-final HIV test to 93% for herpes simplex virus in HIV-infected children from closed organized groups. Signs of active infection in children with laboratory confirmed HIV infection were diagnosed 2.5 times more frequently for HSV infection and chicken pox and 1.8 times more frequently for HHV-6 and pneumocystis than in children with non-final HIV test. Markers of various disease stages with opportunistic infections (01) were detected in children with confirmed HIV-infection: primary acute and latent forms of the infection, reactivation, reconvalescence, whereas in children with non-final HIV test maternal antibodies against herpes virus and pneumocystis predominated. Markers of active infections excluding HSV and HHV-6 were more frequently detected in children from families than in children from closed organized groups. Conclusion. The feature detected - a lower percentage of detection of markers of active forms of 01 in HI V-infected children from social institutions - is determined by the fact that observation of these children is carried out by medical personnel that have the knowledge and experience of prophylaxis of infectious complications in HIV-infected children, whereas quality anti-epidemic regimen is frequently not maintained regarding home children with HIV infection. Another factor facilitating spread of opportunistic infections is the asocial lifestyle of most of the examined families. These data dictate the necessity of enhancement of anti-epidemic regimen and prophylaxis of opportunistic infections in family loci. Not only HIV-infected children, but also all the family members should be examined for markers of herpes virus infection and pneumocystosis in order to detect sources of the infection and timely execution of the prophylaxis measures. |
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DETECTION OF MARKERS OF HERPES VIRUS INFECTION AND PNEUMOCYSTOSIS IN CHILDREN FROM HIV-INFECTED MOTHERS |
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