A retrospective study of the severe and uncommon variants of erythema nodosum leprosum at a tertiary health center in central India
Background: Erythema nodosum leprosum (ENL) classically presents with tender, coppery, evanescent nodules along with constitutional features and visceral involvement. However, uncommon morphological variants of ENL-like erythema nodosum necroticans, erythema multiforme (EM)-like ENL, Sweet's sy...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Vaishali H Wankhade [verfasserIn] Pritica Debnath [verfasserIn] Rajesh Pratap Singh [verfasserIn] Gitesh Sawatkar [verfasserIn] Dharitri Mukund Bhat [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2019 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
In: International Journal of Mycobacteriology - Wolters Kluwer Medknow Publications, 2016, 8(2019), 1, Seite 29-34 |
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| Übergeordnetes Werk: |
volume:8 ; year:2019 ; number:1 ; pages:29-34 |
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Link aufrufen |
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| DOI / URN: |
10.4103/ijmy.ijmy_174_18 |
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| Katalog-ID: |
DOAJ035375531 |
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| 520 | |a Background: Erythema nodosum leprosum (ENL) classically presents with tender, coppery, evanescent nodules along with constitutional features and visceral involvement. However, uncommon morphological variants of ENL-like erythema nodosum necroticans, erythema multiforme (EM)-like ENL, Sweet's syndrome (SS)-like ENL, Lucio phenomenon, and reactive perforating type of ENL have also been described in the literature. The primary objective of this study was to describe the clinical features of the severe and uncommon morphological variants of ENL. Methods: This was an observational case series with retrospective review of records of all ENL patients with ulceronecrotic lesions admitted in the Department of Dermato-venereo-leprology of a tertiary health center of central India over a period of 2 years. Results: Eighteen patients were included, all of whom had ulceronecrotic lesions. Four out of them had EM like ENL, two had SS-like presentation, and one of them had annular bullous lesions over old infiltrated plaques of leprosy. Conclusions: Uncommon variants of ENL can be very commonly misdiagnosed in patients, especially in those who have not been previously diagnosed with leprosy. Hence, a high index of suspicion is required in such cases to avoid delay in the diagnosis and resulting morbidity. | ||
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10.4103/ijmy.ijmy_174_18 doi (DE-627)DOAJ035375531 (DE-599)DOAJfabb86f162384559b6d08f88bd0ed26c DE-627 ger DE-627 rakwb eng QR1-502 Vaishali H Wankhade verfasserin aut A retrospective study of the severe and uncommon variants of erythema nodosum leprosum at a tertiary health center in central India 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Erythema nodosum leprosum (ENL) classically presents with tender, coppery, evanescent nodules along with constitutional features and visceral involvement. However, uncommon morphological variants of ENL-like erythema nodosum necroticans, erythema multiforme (EM)-like ENL, Sweet's syndrome (SS)-like ENL, Lucio phenomenon, and reactive perforating type of ENL have also been described in the literature. The primary objective of this study was to describe the clinical features of the severe and uncommon morphological variants of ENL. Methods: This was an observational case series with retrospective review of records of all ENL patients with ulceronecrotic lesions admitted in the Department of Dermato-venereo-leprology of a tertiary health center of central India over a period of 2 years. Results: Eighteen patients were included, all of whom had ulceronecrotic lesions. Four out of them had EM like ENL, two had SS-like presentation, and one of them had annular bullous lesions over old infiltrated plaques of leprosy. Conclusions: Uncommon variants of ENL can be very commonly misdiagnosed in patients, especially in those who have not been previously diagnosed with leprosy. Hence, a high index of suspicion is required in such cases to avoid delay in the diagnosis and resulting morbidity. Erythema multiforme-like erythema nodosum leprosum erythema nodosum leprosum erythema nodosum necroticans leprosy Sweet's syndrome-like erythema nodosum leprosum Microbiology Pritica Debnath verfasserin aut Rajesh Pratap Singh verfasserin aut Gitesh Sawatkar verfasserin aut Dharitri Mukund Bhat verfasserin aut In International Journal of Mycobacteriology Wolters Kluwer Medknow Publications, 2016 8(2019), 1, Seite 29-34 (DE-627)733750117 (DE-600)2696590-2 2212554X nnns volume:8 year:2019 number:1 pages:29-34 https://doi.org/10.4103/ijmy.ijmy_174_18 kostenfrei https://doaj.org/article/fabb86f162384559b6d08f88bd0ed26c kostenfrei http://www.ijmyco.org/article.asp?issn=2212-5531;year=2019;volume=8;issue=1;spage=29;epage=34;aulast=Wankhade kostenfrei https://doaj.org/toc/2212-5531 Journal toc kostenfrei https://doaj.org/toc/2212-554X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA AR 8 2019 1 29-34 |
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10.4103/ijmy.ijmy_174_18 doi (DE-627)DOAJ035375531 (DE-599)DOAJfabb86f162384559b6d08f88bd0ed26c DE-627 ger DE-627 rakwb eng QR1-502 Vaishali H Wankhade verfasserin aut A retrospective study of the severe and uncommon variants of erythema nodosum leprosum at a tertiary health center in central India 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Erythema nodosum leprosum (ENL) classically presents with tender, coppery, evanescent nodules along with constitutional features and visceral involvement. However, uncommon morphological variants of ENL-like erythema nodosum necroticans, erythema multiforme (EM)-like ENL, Sweet's syndrome (SS)-like ENL, Lucio phenomenon, and reactive perforating type of ENL have also been described in the literature. The primary objective of this study was to describe the clinical features of the severe and uncommon morphological variants of ENL. Methods: This was an observational case series with retrospective review of records of all ENL patients with ulceronecrotic lesions admitted in the Department of Dermato-venereo-leprology of a tertiary health center of central India over a period of 2 years. Results: Eighteen patients were included, all of whom had ulceronecrotic lesions. Four out of them had EM like ENL, two had SS-like presentation, and one of them had annular bullous lesions over old infiltrated plaques of leprosy. Conclusions: Uncommon variants of ENL can be very commonly misdiagnosed in patients, especially in those who have not been previously diagnosed with leprosy. Hence, a high index of suspicion is required in such cases to avoid delay in the diagnosis and resulting morbidity. Erythema multiforme-like erythema nodosum leprosum erythema nodosum leprosum erythema nodosum necroticans leprosy Sweet's syndrome-like erythema nodosum leprosum Microbiology Pritica Debnath verfasserin aut Rajesh Pratap Singh verfasserin aut Gitesh Sawatkar verfasserin aut Dharitri Mukund Bhat verfasserin aut In International Journal of Mycobacteriology Wolters Kluwer Medknow Publications, 2016 8(2019), 1, Seite 29-34 (DE-627)733750117 (DE-600)2696590-2 2212554X nnns volume:8 year:2019 number:1 pages:29-34 https://doi.org/10.4103/ijmy.ijmy_174_18 kostenfrei https://doaj.org/article/fabb86f162384559b6d08f88bd0ed26c kostenfrei http://www.ijmyco.org/article.asp?issn=2212-5531;year=2019;volume=8;issue=1;spage=29;epage=34;aulast=Wankhade kostenfrei https://doaj.org/toc/2212-5531 Journal toc kostenfrei https://doaj.org/toc/2212-554X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA AR 8 2019 1 29-34 |
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10.4103/ijmy.ijmy_174_18 doi (DE-627)DOAJ035375531 (DE-599)DOAJfabb86f162384559b6d08f88bd0ed26c DE-627 ger DE-627 rakwb eng QR1-502 Vaishali H Wankhade verfasserin aut A retrospective study of the severe and uncommon variants of erythema nodosum leprosum at a tertiary health center in central India 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Erythema nodosum leprosum (ENL) classically presents with tender, coppery, evanescent nodules along with constitutional features and visceral involvement. However, uncommon morphological variants of ENL-like erythema nodosum necroticans, erythema multiforme (EM)-like ENL, Sweet's syndrome (SS)-like ENL, Lucio phenomenon, and reactive perforating type of ENL have also been described in the literature. The primary objective of this study was to describe the clinical features of the severe and uncommon morphological variants of ENL. Methods: This was an observational case series with retrospective review of records of all ENL patients with ulceronecrotic lesions admitted in the Department of Dermato-venereo-leprology of a tertiary health center of central India over a period of 2 years. Results: Eighteen patients were included, all of whom had ulceronecrotic lesions. Four out of them had EM like ENL, two had SS-like presentation, and one of them had annular bullous lesions over old infiltrated plaques of leprosy. Conclusions: Uncommon variants of ENL can be very commonly misdiagnosed in patients, especially in those who have not been previously diagnosed with leprosy. Hence, a high index of suspicion is required in such cases to avoid delay in the diagnosis and resulting morbidity. Erythema multiforme-like erythema nodosum leprosum erythema nodosum leprosum erythema nodosum necroticans leprosy Sweet's syndrome-like erythema nodosum leprosum Microbiology Pritica Debnath verfasserin aut Rajesh Pratap Singh verfasserin aut Gitesh Sawatkar verfasserin aut Dharitri Mukund Bhat verfasserin aut In International Journal of Mycobacteriology Wolters Kluwer Medknow Publications, 2016 8(2019), 1, Seite 29-34 (DE-627)733750117 (DE-600)2696590-2 2212554X nnns volume:8 year:2019 number:1 pages:29-34 https://doi.org/10.4103/ijmy.ijmy_174_18 kostenfrei https://doaj.org/article/fabb86f162384559b6d08f88bd0ed26c kostenfrei http://www.ijmyco.org/article.asp?issn=2212-5531;year=2019;volume=8;issue=1;spage=29;epage=34;aulast=Wankhade kostenfrei https://doaj.org/toc/2212-5531 Journal toc kostenfrei https://doaj.org/toc/2212-554X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA AR 8 2019 1 29-34 |
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10.4103/ijmy.ijmy_174_18 doi (DE-627)DOAJ035375531 (DE-599)DOAJfabb86f162384559b6d08f88bd0ed26c DE-627 ger DE-627 rakwb eng QR1-502 Vaishali H Wankhade verfasserin aut A retrospective study of the severe and uncommon variants of erythema nodosum leprosum at a tertiary health center in central India 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Erythema nodosum leprosum (ENL) classically presents with tender, coppery, evanescent nodules along with constitutional features and visceral involvement. However, uncommon morphological variants of ENL-like erythema nodosum necroticans, erythema multiforme (EM)-like ENL, Sweet's syndrome (SS)-like ENL, Lucio phenomenon, and reactive perforating type of ENL have also been described in the literature. The primary objective of this study was to describe the clinical features of the severe and uncommon morphological variants of ENL. Methods: This was an observational case series with retrospective review of records of all ENL patients with ulceronecrotic lesions admitted in the Department of Dermato-venereo-leprology of a tertiary health center of central India over a period of 2 years. Results: Eighteen patients were included, all of whom had ulceronecrotic lesions. Four out of them had EM like ENL, two had SS-like presentation, and one of them had annular bullous lesions over old infiltrated plaques of leprosy. Conclusions: Uncommon variants of ENL can be very commonly misdiagnosed in patients, especially in those who have not been previously diagnosed with leprosy. Hence, a high index of suspicion is required in such cases to avoid delay in the diagnosis and resulting morbidity. Erythema multiforme-like erythema nodosum leprosum erythema nodosum leprosum erythema nodosum necroticans leprosy Sweet's syndrome-like erythema nodosum leprosum Microbiology Pritica Debnath verfasserin aut Rajesh Pratap Singh verfasserin aut Gitesh Sawatkar verfasserin aut Dharitri Mukund Bhat verfasserin aut In International Journal of Mycobacteriology Wolters Kluwer Medknow Publications, 2016 8(2019), 1, Seite 29-34 (DE-627)733750117 (DE-600)2696590-2 2212554X nnns volume:8 year:2019 number:1 pages:29-34 https://doi.org/10.4103/ijmy.ijmy_174_18 kostenfrei https://doaj.org/article/fabb86f162384559b6d08f88bd0ed26c kostenfrei http://www.ijmyco.org/article.asp?issn=2212-5531;year=2019;volume=8;issue=1;spage=29;epage=34;aulast=Wankhade kostenfrei https://doaj.org/toc/2212-5531 Journal toc kostenfrei https://doaj.org/toc/2212-554X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA AR 8 2019 1 29-34 |
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10.4103/ijmy.ijmy_174_18 doi (DE-627)DOAJ035375531 (DE-599)DOAJfabb86f162384559b6d08f88bd0ed26c DE-627 ger DE-627 rakwb eng QR1-502 Vaishali H Wankhade verfasserin aut A retrospective study of the severe and uncommon variants of erythema nodosum leprosum at a tertiary health center in central India 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Erythema nodosum leprosum (ENL) classically presents with tender, coppery, evanescent nodules along with constitutional features and visceral involvement. However, uncommon morphological variants of ENL-like erythema nodosum necroticans, erythema multiforme (EM)-like ENL, Sweet's syndrome (SS)-like ENL, Lucio phenomenon, and reactive perforating type of ENL have also been described in the literature. The primary objective of this study was to describe the clinical features of the severe and uncommon morphological variants of ENL. Methods: This was an observational case series with retrospective review of records of all ENL patients with ulceronecrotic lesions admitted in the Department of Dermato-venereo-leprology of a tertiary health center of central India over a period of 2 years. Results: Eighteen patients were included, all of whom had ulceronecrotic lesions. Four out of them had EM like ENL, two had SS-like presentation, and one of them had annular bullous lesions over old infiltrated plaques of leprosy. Conclusions: Uncommon variants of ENL can be very commonly misdiagnosed in patients, especially in those who have not been previously diagnosed with leprosy. Hence, a high index of suspicion is required in such cases to avoid delay in the diagnosis and resulting morbidity. Erythema multiforme-like erythema nodosum leprosum erythema nodosum leprosum erythema nodosum necroticans leprosy Sweet's syndrome-like erythema nodosum leprosum Microbiology Pritica Debnath verfasserin aut Rajesh Pratap Singh verfasserin aut Gitesh Sawatkar verfasserin aut Dharitri Mukund Bhat verfasserin aut In International Journal of Mycobacteriology Wolters Kluwer Medknow Publications, 2016 8(2019), 1, Seite 29-34 (DE-627)733750117 (DE-600)2696590-2 2212554X nnns volume:8 year:2019 number:1 pages:29-34 https://doi.org/10.4103/ijmy.ijmy_174_18 kostenfrei https://doaj.org/article/fabb86f162384559b6d08f88bd0ed26c kostenfrei http://www.ijmyco.org/article.asp?issn=2212-5531;year=2019;volume=8;issue=1;spage=29;epage=34;aulast=Wankhade kostenfrei https://doaj.org/toc/2212-5531 Journal toc kostenfrei https://doaj.org/toc/2212-554X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA AR 8 2019 1 29-34 |
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However, uncommon morphological variants of ENL-like erythema nodosum necroticans, erythema multiforme (EM)-like ENL, Sweet's syndrome (SS)-like ENL, Lucio phenomenon, and reactive perforating type of ENL have also been described in the literature. The primary objective of this study was to describe the clinical features of the severe and uncommon morphological variants of ENL. Methods: This was an observational case series with retrospective review of records of all ENL patients with ulceronecrotic lesions admitted in the Department of Dermato-venereo-leprology of a tertiary health center of central India over a period of 2 years. Results: Eighteen patients were included, all of whom had ulceronecrotic lesions. Four out of them had EM like ENL, two had SS-like presentation, and one of them had annular bullous lesions over old infiltrated plaques of leprosy. Conclusions: Uncommon variants of ENL can be very commonly misdiagnosed in patients, especially in those who have not been previously diagnosed with leprosy. 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QR1-502 A retrospective study of the severe and uncommon variants of erythema nodosum leprosum at a tertiary health center in central India Erythema multiforme-like erythema nodosum leprosum erythema nodosum leprosum erythema nodosum necroticans leprosy Sweet's syndrome-like erythema nodosum leprosum |
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A retrospective study of the severe and uncommon variants of erythema nodosum leprosum at a tertiary health center in central India |
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Background: Erythema nodosum leprosum (ENL) classically presents with tender, coppery, evanescent nodules along with constitutional features and visceral involvement. However, uncommon morphological variants of ENL-like erythema nodosum necroticans, erythema multiforme (EM)-like ENL, Sweet's syndrome (SS)-like ENL, Lucio phenomenon, and reactive perforating type of ENL have also been described in the literature. The primary objective of this study was to describe the clinical features of the severe and uncommon morphological variants of ENL. Methods: This was an observational case series with retrospective review of records of all ENL patients with ulceronecrotic lesions admitted in the Department of Dermato-venereo-leprology of a tertiary health center of central India over a period of 2 years. Results: Eighteen patients were included, all of whom had ulceronecrotic lesions. Four out of them had EM like ENL, two had SS-like presentation, and one of them had annular bullous lesions over old infiltrated plaques of leprosy. Conclusions: Uncommon variants of ENL can be very commonly misdiagnosed in patients, especially in those who have not been previously diagnosed with leprosy. Hence, a high index of suspicion is required in such cases to avoid delay in the diagnosis and resulting morbidity. |
| abstractGer |
Background: Erythema nodosum leprosum (ENL) classically presents with tender, coppery, evanescent nodules along with constitutional features and visceral involvement. However, uncommon morphological variants of ENL-like erythema nodosum necroticans, erythema multiforme (EM)-like ENL, Sweet's syndrome (SS)-like ENL, Lucio phenomenon, and reactive perforating type of ENL have also been described in the literature. The primary objective of this study was to describe the clinical features of the severe and uncommon morphological variants of ENL. Methods: This was an observational case series with retrospective review of records of all ENL patients with ulceronecrotic lesions admitted in the Department of Dermato-venereo-leprology of a tertiary health center of central India over a period of 2 years. Results: Eighteen patients were included, all of whom had ulceronecrotic lesions. Four out of them had EM like ENL, two had SS-like presentation, and one of them had annular bullous lesions over old infiltrated plaques of leprosy. Conclusions: Uncommon variants of ENL can be very commonly misdiagnosed in patients, especially in those who have not been previously diagnosed with leprosy. Hence, a high index of suspicion is required in such cases to avoid delay in the diagnosis and resulting morbidity. |
| abstract_unstemmed |
Background: Erythema nodosum leprosum (ENL) classically presents with tender, coppery, evanescent nodules along with constitutional features and visceral involvement. However, uncommon morphological variants of ENL-like erythema nodosum necroticans, erythema multiforme (EM)-like ENL, Sweet's syndrome (SS)-like ENL, Lucio phenomenon, and reactive perforating type of ENL have also been described in the literature. The primary objective of this study was to describe the clinical features of the severe and uncommon morphological variants of ENL. Methods: This was an observational case series with retrospective review of records of all ENL patients with ulceronecrotic lesions admitted in the Department of Dermato-venereo-leprology of a tertiary health center of central India over a period of 2 years. Results: Eighteen patients were included, all of whom had ulceronecrotic lesions. Four out of them had EM like ENL, two had SS-like presentation, and one of them had annular bullous lesions over old infiltrated plaques of leprosy. Conclusions: Uncommon variants of ENL can be very commonly misdiagnosed in patients, especially in those who have not been previously diagnosed with leprosy. Hence, a high index of suspicion is required in such cases to avoid delay in the diagnosis and resulting morbidity. |
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