Raman Imaging of Nanocarriers for Drug Delivery

The efficacy of pharmaceutical agents can be greatly improved through nanocarrier delivery. Encapsulation of pharmaceutical agents into a nanocarrier can enhance their bioavailability and biocompatibility, whilst also facilitating targeted drug delivery to specific locations within the body. However...
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Autor*in:	Sally Vanden-Hehir [verfasserIn] William J. Tipping [verfasserIn] Martin Lee [verfasserIn] Valerie G. Brunton [verfasserIn] Anna Williams [verfasserIn] Alison N. Hulme [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2019

Schlagwörter:	Raman imaging nanocarriers drug delivery confocal Raman hyperspectral imaging coherent anti-Stokes Raman scattering stimulated Raman scattering

Übergeordnetes Werk:	In: Nanomaterials - MDPI AG, 2012, 9(2019), 3, p 341
Übergeordnetes Werk:	volume:9 ; year:2019 ; number:3, p 341

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/nano9030341

Katalog-ID:	DOAJ036054267

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allfieldsSound	10.3390/nano9030341 doi (DE-627)DOAJ036054267 (DE-599)DOAJ499787a7d8ae4d95996eb2bde2761b10 DE-627 ger DE-627 rakwb eng QD1-999 Sally Vanden-Hehir verfasserin aut Raman Imaging of Nanocarriers for Drug Delivery 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The efficacy of pharmaceutical agents can be greatly improved through nanocarrier delivery. Encapsulation of pharmaceutical agents into a nanocarrier can enhance their bioavailability and biocompatibility, whilst also facilitating targeted drug delivery to specific locations within the body. However, detailed understanding of the in vivo activity of the nanocarrier-drug conjugate is required prior to regulatory approval as a safe and effective treatment strategy. A comprehensive understanding of how nanocarriers travel to, and interact with, the intended target is required in order to optimize the dosing strategy, reduce potential off-target effects, and unwanted toxic effects. Raman spectroscopy has received much interest as a mechanism for label-free, non-invasive imaging of nanocarrier modes of action in vivo. Advanced Raman imaging techniques, including coherent anti-Stokes Raman scattering (CARS) and stimulated Raman scattering (SRS), are paving the way for rigorous evaluation of nanocarrier activity at the single-cell level. This review focuses on the development of Raman imaging techniques to study organic nanocarrier delivery in cells and tissues. Raman imaging nanocarriers drug delivery confocal Raman hyperspectral imaging coherent anti-Stokes Raman scattering stimulated Raman scattering Chemistry William J. Tipping verfasserin aut Martin Lee verfasserin aut Valerie G. Brunton verfasserin aut Anna Williams verfasserin aut Alison N. Hulme verfasserin aut In Nanomaterials MDPI AG, 2012 9(2019), 3, p 341 (DE-627)718627199 (DE-600)2662255-5 20794991 nnns volume:9 year:2019 number:3, p 341 https://doi.org/10.3390/nano9030341 kostenfrei https://doaj.org/article/499787a7d8ae4d95996eb2bde2761b10 kostenfrei http://www.mdpi.com/2079-4991/9/3/341 kostenfrei https://doaj.org/toc/2079-4991 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2108 GBV_ILN_2119 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2019 3, p 341
language	English
source	In Nanomaterials 9(2019), 3, p 341 volume:9 year:2019 number:3, p 341
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topic_facet	Raman imaging nanocarriers drug delivery confocal Raman hyperspectral imaging coherent anti-Stokes Raman scattering stimulated Raman scattering Chemistry
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container_title	Nanomaterials
authorswithroles_txt_mv	Sally Vanden-Hehir @@aut@@ William J. Tipping @@aut@@ Martin Lee @@aut@@ Valerie G. Brunton @@aut@@ Anna Williams @@aut@@ Alison N. Hulme @@aut@@
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callnumber-first	Q - Science
author	Sally Vanden-Hehir
spellingShingle	Sally Vanden-Hehir misc QD1-999 misc Raman imaging misc nanocarriers misc drug delivery misc confocal Raman misc hyperspectral imaging misc coherent anti-Stokes Raman scattering misc stimulated Raman scattering misc Chemistry Raman Imaging of Nanocarriers for Drug Delivery
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topic_title	QD1-999 Raman Imaging of Nanocarriers for Drug Delivery Raman imaging nanocarriers drug delivery confocal Raman hyperspectral imaging coherent anti-Stokes Raman scattering stimulated Raman scattering
topic	misc QD1-999 misc Raman imaging misc nanocarriers misc drug delivery misc confocal Raman misc hyperspectral imaging misc coherent anti-Stokes Raman scattering misc stimulated Raman scattering misc Chemistry
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title	Raman Imaging of Nanocarriers for Drug Delivery
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title_auth	Raman Imaging of Nanocarriers for Drug Delivery
abstract	The efficacy of pharmaceutical agents can be greatly improved through nanocarrier delivery. Encapsulation of pharmaceutical agents into a nanocarrier can enhance their bioavailability and biocompatibility, whilst also facilitating targeted drug delivery to specific locations within the body. However, detailed understanding of the in vivo activity of the nanocarrier-drug conjugate is required prior to regulatory approval as a safe and effective treatment strategy. A comprehensive understanding of how nanocarriers travel to, and interact with, the intended target is required in order to optimize the dosing strategy, reduce potential off-target effects, and unwanted toxic effects. Raman spectroscopy has received much interest as a mechanism for label-free, non-invasive imaging of nanocarrier modes of action in vivo. Advanced Raman imaging techniques, including coherent anti-Stokes Raman scattering (CARS) and stimulated Raman scattering (SRS), are paving the way for rigorous evaluation of nanocarrier activity at the single-cell level. This review focuses on the development of Raman imaging techniques to study organic nanocarrier delivery in cells and tissues.
abstractGer	The efficacy of pharmaceutical agents can be greatly improved through nanocarrier delivery. Encapsulation of pharmaceutical agents into a nanocarrier can enhance their bioavailability and biocompatibility, whilst also facilitating targeted drug delivery to specific locations within the body. However, detailed understanding of the in vivo activity of the nanocarrier-drug conjugate is required prior to regulatory approval as a safe and effective treatment strategy. A comprehensive understanding of how nanocarriers travel to, and interact with, the intended target is required in order to optimize the dosing strategy, reduce potential off-target effects, and unwanted toxic effects. Raman spectroscopy has received much interest as a mechanism for label-free, non-invasive imaging of nanocarrier modes of action in vivo. Advanced Raman imaging techniques, including coherent anti-Stokes Raman scattering (CARS) and stimulated Raman scattering (SRS), are paving the way for rigorous evaluation of nanocarrier activity at the single-cell level. This review focuses on the development of Raman imaging techniques to study organic nanocarrier delivery in cells and tissues.
abstract_unstemmed	The efficacy of pharmaceutical agents can be greatly improved through nanocarrier delivery. Encapsulation of pharmaceutical agents into a nanocarrier can enhance their bioavailability and biocompatibility, whilst also facilitating targeted drug delivery to specific locations within the body. However, detailed understanding of the in vivo activity of the nanocarrier-drug conjugate is required prior to regulatory approval as a safe and effective treatment strategy. A comprehensive understanding of how nanocarriers travel to, and interact with, the intended target is required in order to optimize the dosing strategy, reduce potential off-target effects, and unwanted toxic effects. Raman spectroscopy has received much interest as a mechanism for label-free, non-invasive imaging of nanocarrier modes of action in vivo. Advanced Raman imaging techniques, including coherent anti-Stokes Raman scattering (CARS) and stimulated Raman scattering (SRS), are paving the way for rigorous evaluation of nanocarrier activity at the single-cell level. This review focuses on the development of Raman imaging techniques to study organic nanocarrier delivery in cells and tissues.
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title_short	Raman Imaging of Nanocarriers for Drug Delivery
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