Early and intermediate-term results of the extracardiac conduit total cavopulmonary connection for functional single-ventricle hearts

Fontan operation has evolved from atriopulmonary connection to total cavopulmonary connection (TCPC) due to its advantages in terms of hemodynamics and reduction of atrium-related complications. We analyzed the early and intermediate-term results of extracardiac conduit TCPC (EC-TCPC) procedure in p...
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Autor*in:	Jun-Yen Pan [verfasserIn] Chu-Chuan Lin [verfasserIn] Chieh-Jen Wu [verfasserIn] Jen-Ping Chang [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2016

Schlagwörter:	Fontan single ventricle total cavopulmonary connection

Übergeordnetes Werk:	In: Journal of the Formosan Medical Association - Elsevier, 2017, 115(2016), 5, Seite 318-324
Übergeordnetes Werk:	volume:115 ; year:2016 ; number:5 ; pages:318-324

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1016/j.jfma.2015.12.011

Katalog-ID:	DOAJ036273783

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spelling	10.1016/j.jfma.2015.12.011 doi (DE-627)DOAJ036273783 (DE-599)DOAJ58706e499baf4d32a7a6251978685eb9 DE-627 ger DE-627 rakwb eng R5-920 Jun-Yen Pan verfasserin aut Early and intermediate-term results of the extracardiac conduit total cavopulmonary connection for functional single-ventricle hearts 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Fontan operation has evolved from atriopulmonary connection to total cavopulmonary connection (TCPC) due to its advantages in terms of hemodynamics and reduction of atrium-related complications. We analyzed the early and intermediate-term results of extracardiac conduit TCPC (EC-TCPC) procedure in patients with functional single ventricle to investigate the risk factors of surgical mortality and intermediate failure. Methods: Retrospective review of the medical records of 88 consecutive patients with functional single ventricle who underwent EC-TCPC from 2000 to 2013 was conducted. Results: The follow-up was 100% complete, ranging from 3 months to 13 years (mean 7.0 ± 3.8 years). There were two (2.3%) hospital and 18 (20.4%) late deaths. The estimated event-free survival rates at 1 year, 5 years, and 10 years were 90.6%, 89.3%, and 77.2%, respectively. On univariate analysis, fenestration was the only risk factor for surgical mortality (p = 0.027). On multivariate analysis, the significant atrioventricular valve regurgitation was the only risk factor for intermediate failure (p = 0.017). Conclusion: The clinical results of EC-TCPC in patients with functional single ventricle were satisfactory. The patients who needed fenestration during operation had higher risk of surgical mortality. Significant atrioventricular valve regurgitation had negative impact on intermediate survival. Fontan single ventricle total cavopulmonary connection Medicine (General) Chu-Chuan Lin verfasserin aut Chieh-Jen Wu verfasserin aut Jen-Ping Chang verfasserin aut In Journal of the Formosan Medical Association Elsevier, 2017 115(2016), 5, Seite 318-324 (DE-627)517812649 (DE-600)2250901-X 09296646 nnns volume:115 year:2016 number:5 pages:318-324 https://doi.org/10.1016/j.jfma.2015.12.011 kostenfrei https://doaj.org/article/58706e499baf4d32a7a6251978685eb9 kostenfrei http://www.sciencedirect.com/science/article/pii/S0929664615004180 kostenfrei https://doaj.org/toc/0929-6646 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 115 2016 5 318-324
allfields_unstemmed	10.1016/j.jfma.2015.12.011 doi (DE-627)DOAJ036273783 (DE-599)DOAJ58706e499baf4d32a7a6251978685eb9 DE-627 ger DE-627 rakwb eng R5-920 Jun-Yen Pan verfasserin aut Early and intermediate-term results of the extracardiac conduit total cavopulmonary connection for functional single-ventricle hearts 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Fontan operation has evolved from atriopulmonary connection to total cavopulmonary connection (TCPC) due to its advantages in terms of hemodynamics and reduction of atrium-related complications. We analyzed the early and intermediate-term results of extracardiac conduit TCPC (EC-TCPC) procedure in patients with functional single ventricle to investigate the risk factors of surgical mortality and intermediate failure. Methods: Retrospective review of the medical records of 88 consecutive patients with functional single ventricle who underwent EC-TCPC from 2000 to 2013 was conducted. Results: The follow-up was 100% complete, ranging from 3 months to 13 years (mean 7.0 ± 3.8 years). There were two (2.3%) hospital and 18 (20.4%) late deaths. The estimated event-free survival rates at 1 year, 5 years, and 10 years were 90.6%, 89.3%, and 77.2%, respectively. On univariate analysis, fenestration was the only risk factor for surgical mortality (p = 0.027). On multivariate analysis, the significant atrioventricular valve regurgitation was the only risk factor for intermediate failure (p = 0.017). Conclusion: The clinical results of EC-TCPC in patients with functional single ventricle were satisfactory. The patients who needed fenestration during operation had higher risk of surgical mortality. Significant atrioventricular valve regurgitation had negative impact on intermediate survival. Fontan single ventricle total cavopulmonary connection Medicine (General) Chu-Chuan Lin verfasserin aut Chieh-Jen Wu verfasserin aut Jen-Ping Chang verfasserin aut In Journal of the Formosan Medical Association Elsevier, 2017 115(2016), 5, Seite 318-324 (DE-627)517812649 (DE-600)2250901-X 09296646 nnns volume:115 year:2016 number:5 pages:318-324 https://doi.org/10.1016/j.jfma.2015.12.011 kostenfrei https://doaj.org/article/58706e499baf4d32a7a6251978685eb9 kostenfrei http://www.sciencedirect.com/science/article/pii/S0929664615004180 kostenfrei https://doaj.org/toc/0929-6646 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 115 2016 5 318-324
allfieldsGer	10.1016/j.jfma.2015.12.011 doi (DE-627)DOAJ036273783 (DE-599)DOAJ58706e499baf4d32a7a6251978685eb9 DE-627 ger DE-627 rakwb eng R5-920 Jun-Yen Pan verfasserin aut Early and intermediate-term results of the extracardiac conduit total cavopulmonary connection for functional single-ventricle hearts 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Fontan operation has evolved from atriopulmonary connection to total cavopulmonary connection (TCPC) due to its advantages in terms of hemodynamics and reduction of atrium-related complications. We analyzed the early and intermediate-term results of extracardiac conduit TCPC (EC-TCPC) procedure in patients with functional single ventricle to investigate the risk factors of surgical mortality and intermediate failure. Methods: Retrospective review of the medical records of 88 consecutive patients with functional single ventricle who underwent EC-TCPC from 2000 to 2013 was conducted. Results: The follow-up was 100% complete, ranging from 3 months to 13 years (mean 7.0 ± 3.8 years). There were two (2.3%) hospital and 18 (20.4%) late deaths. The estimated event-free survival rates at 1 year, 5 years, and 10 years were 90.6%, 89.3%, and 77.2%, respectively. On univariate analysis, fenestration was the only risk factor for surgical mortality (p = 0.027). On multivariate analysis, the significant atrioventricular valve regurgitation was the only risk factor for intermediate failure (p = 0.017). Conclusion: The clinical results of EC-TCPC in patients with functional single ventricle were satisfactory. The patients who needed fenestration during operation had higher risk of surgical mortality. Significant atrioventricular valve regurgitation had negative impact on intermediate survival. Fontan single ventricle total cavopulmonary connection Medicine (General) Chu-Chuan Lin verfasserin aut Chieh-Jen Wu verfasserin aut Jen-Ping Chang verfasserin aut In Journal of the Formosan Medical Association Elsevier, 2017 115(2016), 5, Seite 318-324 (DE-627)517812649 (DE-600)2250901-X 09296646 nnns volume:115 year:2016 number:5 pages:318-324 https://doi.org/10.1016/j.jfma.2015.12.011 kostenfrei https://doaj.org/article/58706e499baf4d32a7a6251978685eb9 kostenfrei http://www.sciencedirect.com/science/article/pii/S0929664615004180 kostenfrei https://doaj.org/toc/0929-6646 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 115 2016 5 318-324
allfieldsSound	10.1016/j.jfma.2015.12.011 doi (DE-627)DOAJ036273783 (DE-599)DOAJ58706e499baf4d32a7a6251978685eb9 DE-627 ger DE-627 rakwb eng R5-920 Jun-Yen Pan verfasserin aut Early and intermediate-term results of the extracardiac conduit total cavopulmonary connection for functional single-ventricle hearts 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Fontan operation has evolved from atriopulmonary connection to total cavopulmonary connection (TCPC) due to its advantages in terms of hemodynamics and reduction of atrium-related complications. We analyzed the early and intermediate-term results of extracardiac conduit TCPC (EC-TCPC) procedure in patients with functional single ventricle to investigate the risk factors of surgical mortality and intermediate failure. Methods: Retrospective review of the medical records of 88 consecutive patients with functional single ventricle who underwent EC-TCPC from 2000 to 2013 was conducted. Results: The follow-up was 100% complete, ranging from 3 months to 13 years (mean 7.0 ± 3.8 years). There were two (2.3%) hospital and 18 (20.4%) late deaths. The estimated event-free survival rates at 1 year, 5 years, and 10 years were 90.6%, 89.3%, and 77.2%, respectively. On univariate analysis, fenestration was the only risk factor for surgical mortality (p = 0.027). On multivariate analysis, the significant atrioventricular valve regurgitation was the only risk factor for intermediate failure (p = 0.017). Conclusion: The clinical results of EC-TCPC in patients with functional single ventricle were satisfactory. The patients who needed fenestration during operation had higher risk of surgical mortality. Significant atrioventricular valve regurgitation had negative impact on intermediate survival. Fontan single ventricle total cavopulmonary connection Medicine (General) Chu-Chuan Lin verfasserin aut Chieh-Jen Wu verfasserin aut Jen-Ping Chang verfasserin aut In Journal of the Formosan Medical Association Elsevier, 2017 115(2016), 5, Seite 318-324 (DE-627)517812649 (DE-600)2250901-X 09296646 nnns volume:115 year:2016 number:5 pages:318-324 https://doi.org/10.1016/j.jfma.2015.12.011 kostenfrei https://doaj.org/article/58706e499baf4d32a7a6251978685eb9 kostenfrei http://www.sciencedirect.com/science/article/pii/S0929664615004180 kostenfrei https://doaj.org/toc/0929-6646 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 115 2016 5 318-324
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authorswithroles_txt_mv	Jun-Yen Pan @@aut@@ Chu-Chuan Lin @@aut@@ Chieh-Jen Wu @@aut@@ Jen-Ping Chang @@aut@@
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callnumber-first	R - Medicine
author	Jun-Yen Pan
spellingShingle	Jun-Yen Pan misc R5-920 misc Fontan misc single ventricle misc total cavopulmonary connection misc Medicine (General) Early and intermediate-term results of the extracardiac conduit total cavopulmonary connection for functional single-ventricle hearts
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topic_title	R5-920 Early and intermediate-term results of the extracardiac conduit total cavopulmonary connection for functional single-ventricle hearts Fontan single ventricle total cavopulmonary connection
topic	misc R5-920 misc Fontan misc single ventricle misc total cavopulmonary connection misc Medicine (General)
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title	Early and intermediate-term results of the extracardiac conduit total cavopulmonary connection for functional single-ventricle hearts
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title_full	Early and intermediate-term results of the extracardiac conduit total cavopulmonary connection for functional single-ventricle hearts
author_sort	Jun-Yen Pan
journal	Journal of the Formosan Medical Association
journalStr	Journal of the Formosan Medical Association
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author_browse	Jun-Yen Pan Chu-Chuan Lin Chieh-Jen Wu Jen-Ping Chang
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author-letter	Jun-Yen Pan
doi_str_mv	10.1016/j.jfma.2015.12.011
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title_sort	early and intermediate-term results of the extracardiac conduit total cavopulmonary connection for functional single-ventricle hearts
callnumber	R5-920
title_auth	Early and intermediate-term results of the extracardiac conduit total cavopulmonary connection for functional single-ventricle hearts
abstract	Fontan operation has evolved from atriopulmonary connection to total cavopulmonary connection (TCPC) due to its advantages in terms of hemodynamics and reduction of atrium-related complications. We analyzed the early and intermediate-term results of extracardiac conduit TCPC (EC-TCPC) procedure in patients with functional single ventricle to investigate the risk factors of surgical mortality and intermediate failure. Methods: Retrospective review of the medical records of 88 consecutive patients with functional single ventricle who underwent EC-TCPC from 2000 to 2013 was conducted. Results: The follow-up was 100% complete, ranging from 3 months to 13 years (mean 7.0 ± 3.8 years). There were two (2.3%) hospital and 18 (20.4%) late deaths. The estimated event-free survival rates at 1 year, 5 years, and 10 years were 90.6%, 89.3%, and 77.2%, respectively. On univariate analysis, fenestration was the only risk factor for surgical mortality (p = 0.027). On multivariate analysis, the significant atrioventricular valve regurgitation was the only risk factor for intermediate failure (p = 0.017). Conclusion: The clinical results of EC-TCPC in patients with functional single ventricle were satisfactory. The patients who needed fenestration during operation had higher risk of surgical mortality. Significant atrioventricular valve regurgitation had negative impact on intermediate survival.
abstractGer	Fontan operation has evolved from atriopulmonary connection to total cavopulmonary connection (TCPC) due to its advantages in terms of hemodynamics and reduction of atrium-related complications. We analyzed the early and intermediate-term results of extracardiac conduit TCPC (EC-TCPC) procedure in patients with functional single ventricle to investigate the risk factors of surgical mortality and intermediate failure. Methods: Retrospective review of the medical records of 88 consecutive patients with functional single ventricle who underwent EC-TCPC from 2000 to 2013 was conducted. Results: The follow-up was 100% complete, ranging from 3 months to 13 years (mean 7.0 ± 3.8 years). There were two (2.3%) hospital and 18 (20.4%) late deaths. The estimated event-free survival rates at 1 year, 5 years, and 10 years were 90.6%, 89.3%, and 77.2%, respectively. On univariate analysis, fenestration was the only risk factor for surgical mortality (p = 0.027). On multivariate analysis, the significant atrioventricular valve regurgitation was the only risk factor for intermediate failure (p = 0.017). Conclusion: The clinical results of EC-TCPC in patients with functional single ventricle were satisfactory. The patients who needed fenestration during operation had higher risk of surgical mortality. Significant atrioventricular valve regurgitation had negative impact on intermediate survival.
abstract_unstemmed	Fontan operation has evolved from atriopulmonary connection to total cavopulmonary connection (TCPC) due to its advantages in terms of hemodynamics and reduction of atrium-related complications. We analyzed the early and intermediate-term results of extracardiac conduit TCPC (EC-TCPC) procedure in patients with functional single ventricle to investigate the risk factors of surgical mortality and intermediate failure. Methods: Retrospective review of the medical records of 88 consecutive patients with functional single ventricle who underwent EC-TCPC from 2000 to 2013 was conducted. Results: The follow-up was 100% complete, ranging from 3 months to 13 years (mean 7.0 ± 3.8 years). There were two (2.3%) hospital and 18 (20.4%) late deaths. The estimated event-free survival rates at 1 year, 5 years, and 10 years were 90.6%, 89.3%, and 77.2%, respectively. On univariate analysis, fenestration was the only risk factor for surgical mortality (p = 0.027). On multivariate analysis, the significant atrioventricular valve regurgitation was the only risk factor for intermediate failure (p = 0.017). Conclusion: The clinical results of EC-TCPC in patients with functional single ventricle were satisfactory. The patients who needed fenestration during operation had higher risk of surgical mortality. Significant atrioventricular valve regurgitation had negative impact on intermediate survival.
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title_short	Early and intermediate-term results of the extracardiac conduit total cavopulmonary connection for functional single-ventricle hearts
url	https://doi.org/10.1016/j.jfma.2015.12.011 https://doaj.org/article/58706e499baf4d32a7a6251978685eb9 http://www.sciencedirect.com/science/article/pii/S0929664615004180 https://doaj.org/toc/0929-6646
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author2	Chu-Chuan Lin Chieh-Jen Wu Jen-Ping Chang
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up_date	2024-07-03T19:39:32.898Z
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Early and intermediate-term results of the extracardiac conduit total cavopulmonary connection for functional single-ventricle hearts

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