Synthesis of resorcinolic lipids bearing structural similarities to cytosporone A
Inspired by the structure and biological activities of resorcinolic lipids and, particularly cytosporone A- a potent inhibitor of plantule germination and growth, we have performed the synthesis of the analogs 3-heptyl-3-hydroxy-5,7-dimethoxy-2-benzofuran-1(3H)-one (1) and 3-heptyl-3-hydroxy-4,6-dim...
Ausführliche Beschreibung
Autor*in: |
Edson dos Anjos dos Santos [verfasserIn] Adilson Beatriz [verfasserIn] Dênis Pires de Lima [verfasserIn] Maria Rita Marques [verfasserIn] Carla Braga Leite [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch ; Spanisch ; Portugiesisch |
Erschienen: |
2009 |
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Übergeordnetes Werk: |
In: Química Nova - Sociedade Brasileira de Química, 2004, 32(2009), 7, Seite 1856-1859 |
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Übergeordnetes Werk: |
volume:32 ; year:2009 ; number:7 ; pages:1856-1859 |
Links: |
Link aufrufen |
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DOI / URN: |
10.1590/S0100-40422009000700032 |
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Katalog-ID: |
DOAJ036572829 |
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10.1590/S0100-40422009000700032 doi (DE-627)DOAJ036572829 (DE-599)DOAJ0780691c4b644dd39cfeafd818afc9cf DE-627 ger DE-627 rakwb eng spa por QD1-999 Edson dos Anjos dos Santos verfasserin aut Synthesis of resorcinolic lipids bearing structural similarities to cytosporone A 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Inspired by the structure and biological activities of resorcinolic lipids and, particularly cytosporone A- a potent inhibitor of plantule germination and growth, we have performed the synthesis of the analogs 3-heptyl-3-hydroxy-5,7-dimethoxy-2-benzofuran-1(3H)-one (1) and 3-heptyl-3-hydroxy-4,6-dimethoxy-2-benzofuran-1(3H)-one (2). The intermediates and products were submitted to allelopathic test using Lactuca sativa L. seeds. Target compound 1 showed an inhibitory effect on germination and growth of hypocotyl and radicle in milimolar range. resorcinolic lipid cytosporone A allelopathic activity Chemistry Adilson Beatriz verfasserin aut Dênis Pires de Lima verfasserin aut Maria Rita Marques verfasserin aut Carla Braga Leite verfasserin aut In Química Nova Sociedade Brasileira de Química, 2004 32(2009), 7, Seite 1856-1859 (DE-627)331773309 (DE-600)2053241-6 16787064 nnns volume:32 year:2009 number:7 pages:1856-1859 https://doi.org/10.1590/S0100-40422009000700032 kostenfrei https://doaj.org/article/0780691c4b644dd39cfeafd818afc9cf kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422009000700032 kostenfrei https://doaj.org/toc/0100-4042 Journal toc kostenfrei https://doaj.org/toc/1678-7064 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 32 2009 7 1856-1859 |
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10.1590/S0100-40422009000700032 doi (DE-627)DOAJ036572829 (DE-599)DOAJ0780691c4b644dd39cfeafd818afc9cf DE-627 ger DE-627 rakwb eng spa por QD1-999 Edson dos Anjos dos Santos verfasserin aut Synthesis of resorcinolic lipids bearing structural similarities to cytosporone A 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Inspired by the structure and biological activities of resorcinolic lipids and, particularly cytosporone A- a potent inhibitor of plantule germination and growth, we have performed the synthesis of the analogs 3-heptyl-3-hydroxy-5,7-dimethoxy-2-benzofuran-1(3H)-one (1) and 3-heptyl-3-hydroxy-4,6-dimethoxy-2-benzofuran-1(3H)-one (2). The intermediates and products were submitted to allelopathic test using Lactuca sativa L. seeds. Target compound 1 showed an inhibitory effect on germination and growth of hypocotyl and radicle in milimolar range. resorcinolic lipid cytosporone A allelopathic activity Chemistry Adilson Beatriz verfasserin aut Dênis Pires de Lima verfasserin aut Maria Rita Marques verfasserin aut Carla Braga Leite verfasserin aut In Química Nova Sociedade Brasileira de Química, 2004 32(2009), 7, Seite 1856-1859 (DE-627)331773309 (DE-600)2053241-6 16787064 nnns volume:32 year:2009 number:7 pages:1856-1859 https://doi.org/10.1590/S0100-40422009000700032 kostenfrei https://doaj.org/article/0780691c4b644dd39cfeafd818afc9cf kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422009000700032 kostenfrei https://doaj.org/toc/0100-4042 Journal toc kostenfrei https://doaj.org/toc/1678-7064 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 32 2009 7 1856-1859 |
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10.1590/S0100-40422009000700032 doi (DE-627)DOAJ036572829 (DE-599)DOAJ0780691c4b644dd39cfeafd818afc9cf DE-627 ger DE-627 rakwb eng spa por QD1-999 Edson dos Anjos dos Santos verfasserin aut Synthesis of resorcinolic lipids bearing structural similarities to cytosporone A 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Inspired by the structure and biological activities of resorcinolic lipids and, particularly cytosporone A- a potent inhibitor of plantule germination and growth, we have performed the synthesis of the analogs 3-heptyl-3-hydroxy-5,7-dimethoxy-2-benzofuran-1(3H)-one (1) and 3-heptyl-3-hydroxy-4,6-dimethoxy-2-benzofuran-1(3H)-one (2). The intermediates and products were submitted to allelopathic test using Lactuca sativa L. seeds. Target compound 1 showed an inhibitory effect on germination and growth of hypocotyl and radicle in milimolar range. resorcinolic lipid cytosporone A allelopathic activity Chemistry Adilson Beatriz verfasserin aut Dênis Pires de Lima verfasserin aut Maria Rita Marques verfasserin aut Carla Braga Leite verfasserin aut In Química Nova Sociedade Brasileira de Química, 2004 32(2009), 7, Seite 1856-1859 (DE-627)331773309 (DE-600)2053241-6 16787064 nnns volume:32 year:2009 number:7 pages:1856-1859 https://doi.org/10.1590/S0100-40422009000700032 kostenfrei https://doaj.org/article/0780691c4b644dd39cfeafd818afc9cf kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422009000700032 kostenfrei https://doaj.org/toc/0100-4042 Journal toc kostenfrei https://doaj.org/toc/1678-7064 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 32 2009 7 1856-1859 |
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10.1590/S0100-40422009000700032 doi (DE-627)DOAJ036572829 (DE-599)DOAJ0780691c4b644dd39cfeafd818afc9cf DE-627 ger DE-627 rakwb eng spa por QD1-999 Edson dos Anjos dos Santos verfasserin aut Synthesis of resorcinolic lipids bearing structural similarities to cytosporone A 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Inspired by the structure and biological activities of resorcinolic lipids and, particularly cytosporone A- a potent inhibitor of plantule germination and growth, we have performed the synthesis of the analogs 3-heptyl-3-hydroxy-5,7-dimethoxy-2-benzofuran-1(3H)-one (1) and 3-heptyl-3-hydroxy-4,6-dimethoxy-2-benzofuran-1(3H)-one (2). The intermediates and products were submitted to allelopathic test using Lactuca sativa L. seeds. Target compound 1 showed an inhibitory effect on germination and growth of hypocotyl and radicle in milimolar range. resorcinolic lipid cytosporone A allelopathic activity Chemistry Adilson Beatriz verfasserin aut Dênis Pires de Lima verfasserin aut Maria Rita Marques verfasserin aut Carla Braga Leite verfasserin aut In Química Nova Sociedade Brasileira de Química, 2004 32(2009), 7, Seite 1856-1859 (DE-627)331773309 (DE-600)2053241-6 16787064 nnns volume:32 year:2009 number:7 pages:1856-1859 https://doi.org/10.1590/S0100-40422009000700032 kostenfrei https://doaj.org/article/0780691c4b644dd39cfeafd818afc9cf kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422009000700032 kostenfrei https://doaj.org/toc/0100-4042 Journal toc kostenfrei https://doaj.org/toc/1678-7064 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 32 2009 7 1856-1859 |
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Synthesis of resorcinolic lipids bearing structural similarities to cytosporone A |
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Inspired by the structure and biological activities of resorcinolic lipids and, particularly cytosporone A- a potent inhibitor of plantule germination and growth, we have performed the synthesis of the analogs 3-heptyl-3-hydroxy-5,7-dimethoxy-2-benzofuran-1(3H)-one (1) and 3-heptyl-3-hydroxy-4,6-dimethoxy-2-benzofuran-1(3H)-one (2). The intermediates and products were submitted to allelopathic test using Lactuca sativa L. seeds. Target compound 1 showed an inhibitory effect on germination and growth of hypocotyl and radicle in milimolar range. |
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Inspired by the structure and biological activities of resorcinolic lipids and, particularly cytosporone A- a potent inhibitor of plantule germination and growth, we have performed the synthesis of the analogs 3-heptyl-3-hydroxy-5,7-dimethoxy-2-benzofuran-1(3H)-one (1) and 3-heptyl-3-hydroxy-4,6-dimethoxy-2-benzofuran-1(3H)-one (2). The intermediates and products were submitted to allelopathic test using Lactuca sativa L. seeds. Target compound 1 showed an inhibitory effect on germination and growth of hypocotyl and radicle in milimolar range. |
abstract_unstemmed |
Inspired by the structure and biological activities of resorcinolic lipids and, particularly cytosporone A- a potent inhibitor of plantule germination and growth, we have performed the synthesis of the analogs 3-heptyl-3-hydroxy-5,7-dimethoxy-2-benzofuran-1(3H)-one (1) and 3-heptyl-3-hydroxy-4,6-dimethoxy-2-benzofuran-1(3H)-one (2). The intermediates and products were submitted to allelopathic test using Lactuca sativa L. seeds. Target compound 1 showed an inhibitory effect on germination and growth of hypocotyl and radicle in milimolar range. |
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