Accessory Gene Regulator Types of Staphylococcus aureus Isolated in Gorgan, North of Iran

Background: Staphylococcus aureus is a gram-positive bacterium that has remained a persistent pathogen, causing infections such as endocarditis, meningitis, and toxic shock syndrome in humans. The accessory gene regulator (agr) system of Staphylococcus aureus is responsible for controlling the expre...
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Autor*in:	Meysam Hasannejad Bibalan [verfasserIn] Fatemeh Shakeri [verfasserIn] Naeme Javid [verfasserIn] Amir Ghaemi [verfasserIn] Ezzat Allah Ghaemi [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2014

Schlagwörter:	s. aureus agr group genes pcr

Übergeordnetes Werk:	In: Journal of Clinical and Diagnostic Research - JCDR Research and Publications Private Limited, 2009, 8(2014), 4, Seite DC07-DC09
Übergeordnetes Werk:	volume:8 ; year:2014 ; number:4 ; pages:DC07-DC09

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.7860/JCDR/2014/6971.4219

Katalog-ID:	DOAJ037782193

Internformat


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100	0		\|a Meysam Hasannejad Bibalan \|e verfasserin \|4 aut
245	1	0	\|a Accessory Gene Regulator Types of Staphylococcus aureus Isolated in Gorgan, North of Iran
264		1	\|c 2014
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520			\|a Background: Staphylococcus aureus is a gram-positive bacterium that has remained a persistent pathogen, causing infections such as endocarditis, meningitis, and toxic shock syndrome in humans. The accessory gene regulator (agr) system of Staphylococcus aureus is responsible for controlling the expression of many genes that code for virulence factors. In this study, we assessed the S. aureus agr Group, based on their source of isolation, in Gorgan, North of Iran. Materials and Methods: DNA of 194 S. aureus isolates was extracted by lysozyme-phenol chloroform method, which included 85 clinical samples, 58 samples which were isolated from noses of health care workers and 51 cases which were obtained from food products in Gorgan, northern Iran. PCR-based assays were used to evaluate agr locus nucleotide polymorphism for the identification of agr specificity Group. Distributions of each agr Group were determined and comparison between different sources was assessed by X2 . A p-value of <0.05 was considered as significant. Results: The majority of isolates belonged to agr Group I (43.3%), followed by agr Group III (28.87%), agr Group II (22.68%), and agr Group IV (5.15%). In our study, a majority of S. aureus isolates were recovered from health care workers and food product specimens were of agr Group I and isolates which were recovered from patients were of agr Group III. These differences were statistically significant (P=0.005). There was no statistical difference between the source of isolation of clinical samples of S. aureus and agr type. Conclusion: Agr Group I was predominant among health care workers and food product specimens in Gorgan, North of Iran, but in strains which were isolated from patients, agr Group III was predominant. Investigating the possible role of agr Group III in Staphylococcus aureus infection in future studies is recommended.
650		4	\|a s. aureus
650		4	\|a agr group genes
650		4	\|a pcr
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653		0	\|a R
700	0		\|a Fatemeh Shakeri \|e verfasserin \|4 aut
700	0		\|a Naeme Javid \|e verfasserin \|4 aut
700	0		\|a Amir Ghaemi \|e verfasserin \|4 aut
700	0		\|a Ezzat Allah Ghaemi \|e verfasserin \|4 aut
773	0	8	\|i In \|t Journal of Clinical and Diagnostic Research \|d JCDR Research and Publications Private Limited, 2009 \|g 8(2014), 4, Seite DC07-DC09 \|w (DE-627)789478048 \|w (DE-600)2775283-5 \|x 0973709X \|7 nnns
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912			\|a SSG-OLC-PHA
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912			\|a GBV_ILN_22
912			\|a GBV_ILN_23
912			\|a GBV_ILN_24
912			\|a GBV_ILN_39
912			\|a GBV_ILN_40
912			\|a GBV_ILN_60
912			\|a GBV_ILN_62
912			\|a GBV_ILN_63
912			\|a GBV_ILN_65
912			\|a GBV_ILN_69
912			\|a GBV_ILN_73
912			\|a GBV_ILN_74
912			\|a GBV_ILN_95
912			\|a GBV_ILN_105
912			\|a GBV_ILN_110
912			\|a GBV_ILN_151
912			\|a GBV_ILN_161
912			\|a GBV_ILN_170
912			\|a GBV_ILN_206
912			\|a GBV_ILN_213
912			\|a GBV_ILN_230
912			\|a GBV_ILN_285
912			\|a GBV_ILN_293
912			\|a GBV_ILN_602
912			\|a GBV_ILN_2005
912			\|a GBV_ILN_2009
912			\|a GBV_ILN_2011
912			\|a GBV_ILN_2014
912			\|a GBV_ILN_2055
912			\|a GBV_ILN_2111
912			\|a GBV_ILN_4012
912			\|a GBV_ILN_4037
912			\|a GBV_ILN_4112
912			\|a GBV_ILN_4125
912			\|a GBV_ILN_4126
912			\|a GBV_ILN_4249
912			\|a GBV_ILN_4305
912			\|a GBV_ILN_4306
912			\|a GBV_ILN_4307
912			\|a GBV_ILN_4313
912			\|a GBV_ILN_4322
912			\|a GBV_ILN_4323
912			\|a GBV_ILN_4324
912			\|a GBV_ILN_4325
912			\|a GBV_ILN_4338
912			\|a GBV_ILN_4367
912			\|a GBV_ILN_4700
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Indexfelder

author_variant	m h b mhb f s fs n j nj a g ag e a g eag
matchkey_str	article:0973709X:2014----::cesrgnrgltryeosahlccuaruioae
hierarchy_sort_str	2014
publishDate	2014
allfields	10.7860/JCDR/2014/6971.4219 doi (DE-627)DOAJ037782193 (DE-599)DOAJca8809ed1cf243f084a2c8a36e17ccd5 DE-627 ger DE-627 rakwb eng Meysam Hasannejad Bibalan verfasserin aut Accessory Gene Regulator Types of Staphylococcus aureus Isolated in Gorgan, North of Iran 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Staphylococcus aureus is a gram-positive bacterium that has remained a persistent pathogen, causing infections such as endocarditis, meningitis, and toxic shock syndrome in humans. The accessory gene regulator (agr) system of Staphylococcus aureus is responsible for controlling the expression of many genes that code for virulence factors. In this study, we assessed the S. aureus agr Group, based on their source of isolation, in Gorgan, North of Iran. Materials and Methods: DNA of 194 S. aureus isolates was extracted by lysozyme-phenol chloroform method, which included 85 clinical samples, 58 samples which were isolated from noses of health care workers and 51 cases which were obtained from food products in Gorgan, northern Iran. PCR-based assays were used to evaluate agr locus nucleotide polymorphism for the identification of agr specificity Group. Distributions of each agr Group were determined and comparison between different sources was assessed by X2 . A p-value of <0.05 was considered as significant. Results: The majority of isolates belonged to agr Group I (43.3%), followed by agr Group III (28.87%), agr Group II (22.68%), and agr Group IV (5.15%). In our study, a majority of S. aureus isolates were recovered from health care workers and food product specimens were of agr Group I and isolates which were recovered from patients were of agr Group III. These differences were statistically significant (P=0.005). There was no statistical difference between the source of isolation of clinical samples of S. aureus and agr type. Conclusion: Agr Group I was predominant among health care workers and food product specimens in Gorgan, North of Iran, but in strains which were isolated from patients, agr Group III was predominant. Investigating the possible role of agr Group III in Staphylococcus aureus infection in future studies is recommended. s. aureus agr group genes pcr Medicine R Fatemeh Shakeri verfasserin aut Naeme Javid verfasserin aut Amir Ghaemi verfasserin aut Ezzat Allah Ghaemi verfasserin aut In Journal of Clinical and Diagnostic Research JCDR Research and Publications Private Limited, 2009 8(2014), 4, Seite DC07-DC09 (DE-627)789478048 (DE-600)2775283-5 0973709X nnns volume:8 year:2014 number:4 pages:DC07-DC09 https://doi.org/10.7860/JCDR/2014/6971.4219 kostenfrei https://doaj.org/article/ca8809ed1cf243f084a2c8a36e17ccd5 kostenfrei https://jcdr.net/articles/PDF/4219/6971_CE(Ra)_E(C)_F(P)_PF1(PAK)_PFA(H)_PFA2(AK).pdf kostenfrei https://doaj.org/toc/2249-782X Journal toc kostenfrei https://doaj.org/toc/0973-709X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2014 4 DC07-DC09
spelling	10.7860/JCDR/2014/6971.4219 doi (DE-627)DOAJ037782193 (DE-599)DOAJca8809ed1cf243f084a2c8a36e17ccd5 DE-627 ger DE-627 rakwb eng Meysam Hasannejad Bibalan verfasserin aut Accessory Gene Regulator Types of Staphylococcus aureus Isolated in Gorgan, North of Iran 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Staphylococcus aureus is a gram-positive bacterium that has remained a persistent pathogen, causing infections such as endocarditis, meningitis, and toxic shock syndrome in humans. The accessory gene regulator (agr) system of Staphylococcus aureus is responsible for controlling the expression of many genes that code for virulence factors. In this study, we assessed the S. aureus agr Group, based on their source of isolation, in Gorgan, North of Iran. Materials and Methods: DNA of 194 S. aureus isolates was extracted by lysozyme-phenol chloroform method, which included 85 clinical samples, 58 samples which were isolated from noses of health care workers and 51 cases which were obtained from food products in Gorgan, northern Iran. PCR-based assays were used to evaluate agr locus nucleotide polymorphism for the identification of agr specificity Group. Distributions of each agr Group were determined and comparison between different sources was assessed by X2 . A p-value of <0.05 was considered as significant. Results: The majority of isolates belonged to agr Group I (43.3%), followed by agr Group III (28.87%), agr Group II (22.68%), and agr Group IV (5.15%). In our study, a majority of S. aureus isolates were recovered from health care workers and food product specimens were of agr Group I and isolates which were recovered from patients were of agr Group III. These differences were statistically significant (P=0.005). There was no statistical difference between the source of isolation of clinical samples of S. aureus and agr type. Conclusion: Agr Group I was predominant among health care workers and food product specimens in Gorgan, North of Iran, but in strains which were isolated from patients, agr Group III was predominant. Investigating the possible role of agr Group III in Staphylococcus aureus infection in future studies is recommended. s. aureus agr group genes pcr Medicine R Fatemeh Shakeri verfasserin aut Naeme Javid verfasserin aut Amir Ghaemi verfasserin aut Ezzat Allah Ghaemi verfasserin aut In Journal of Clinical and Diagnostic Research JCDR Research and Publications Private Limited, 2009 8(2014), 4, Seite DC07-DC09 (DE-627)789478048 (DE-600)2775283-5 0973709X nnns volume:8 year:2014 number:4 pages:DC07-DC09 https://doi.org/10.7860/JCDR/2014/6971.4219 kostenfrei https://doaj.org/article/ca8809ed1cf243f084a2c8a36e17ccd5 kostenfrei https://jcdr.net/articles/PDF/4219/6971_CE(Ra)_E(C)_F(P)_PF1(PAK)_PFA(H)_PFA2(AK).pdf kostenfrei https://doaj.org/toc/2249-782X Journal toc kostenfrei https://doaj.org/toc/0973-709X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2014 4 DC07-DC09
allfields_unstemmed	10.7860/JCDR/2014/6971.4219 doi (DE-627)DOAJ037782193 (DE-599)DOAJca8809ed1cf243f084a2c8a36e17ccd5 DE-627 ger DE-627 rakwb eng Meysam Hasannejad Bibalan verfasserin aut Accessory Gene Regulator Types of Staphylococcus aureus Isolated in Gorgan, North of Iran 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Staphylococcus aureus is a gram-positive bacterium that has remained a persistent pathogen, causing infections such as endocarditis, meningitis, and toxic shock syndrome in humans. The accessory gene regulator (agr) system of Staphylococcus aureus is responsible for controlling the expression of many genes that code for virulence factors. In this study, we assessed the S. aureus agr Group, based on their source of isolation, in Gorgan, North of Iran. Materials and Methods: DNA of 194 S. aureus isolates was extracted by lysozyme-phenol chloroform method, which included 85 clinical samples, 58 samples which were isolated from noses of health care workers and 51 cases which were obtained from food products in Gorgan, northern Iran. PCR-based assays were used to evaluate agr locus nucleotide polymorphism for the identification of agr specificity Group. Distributions of each agr Group were determined and comparison between different sources was assessed by X2 . A p-value of <0.05 was considered as significant. Results: The majority of isolates belonged to agr Group I (43.3%), followed by agr Group III (28.87%), agr Group II (22.68%), and agr Group IV (5.15%). In our study, a majority of S. aureus isolates were recovered from health care workers and food product specimens were of agr Group I and isolates which were recovered from patients were of agr Group III. These differences were statistically significant (P=0.005). There was no statistical difference between the source of isolation of clinical samples of S. aureus and agr type. Conclusion: Agr Group I was predominant among health care workers and food product specimens in Gorgan, North of Iran, but in strains which were isolated from patients, agr Group III was predominant. Investigating the possible role of agr Group III in Staphylococcus aureus infection in future studies is recommended. s. aureus agr group genes pcr Medicine R Fatemeh Shakeri verfasserin aut Naeme Javid verfasserin aut Amir Ghaemi verfasserin aut Ezzat Allah Ghaemi verfasserin aut In Journal of Clinical and Diagnostic Research JCDR Research and Publications Private Limited, 2009 8(2014), 4, Seite DC07-DC09 (DE-627)789478048 (DE-600)2775283-5 0973709X nnns volume:8 year:2014 number:4 pages:DC07-DC09 https://doi.org/10.7860/JCDR/2014/6971.4219 kostenfrei https://doaj.org/article/ca8809ed1cf243f084a2c8a36e17ccd5 kostenfrei https://jcdr.net/articles/PDF/4219/6971_CE(Ra)_E(C)_F(P)_PF1(PAK)_PFA(H)_PFA2(AK).pdf kostenfrei https://doaj.org/toc/2249-782X Journal toc kostenfrei https://doaj.org/toc/0973-709X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2014 4 DC07-DC09
allfieldsGer	10.7860/JCDR/2014/6971.4219 doi (DE-627)DOAJ037782193 (DE-599)DOAJca8809ed1cf243f084a2c8a36e17ccd5 DE-627 ger DE-627 rakwb eng Meysam Hasannejad Bibalan verfasserin aut Accessory Gene Regulator Types of Staphylococcus aureus Isolated in Gorgan, North of Iran 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Staphylococcus aureus is a gram-positive bacterium that has remained a persistent pathogen, causing infections such as endocarditis, meningitis, and toxic shock syndrome in humans. The accessory gene regulator (agr) system of Staphylococcus aureus is responsible for controlling the expression of many genes that code for virulence factors. In this study, we assessed the S. aureus agr Group, based on their source of isolation, in Gorgan, North of Iran. Materials and Methods: DNA of 194 S. aureus isolates was extracted by lysozyme-phenol chloroform method, which included 85 clinical samples, 58 samples which were isolated from noses of health care workers and 51 cases which were obtained from food products in Gorgan, northern Iran. PCR-based assays were used to evaluate agr locus nucleotide polymorphism for the identification of agr specificity Group. Distributions of each agr Group were determined and comparison between different sources was assessed by X2 . A p-value of <0.05 was considered as significant. Results: The majority of isolates belonged to agr Group I (43.3%), followed by agr Group III (28.87%), agr Group II (22.68%), and agr Group IV (5.15%). In our study, a majority of S. aureus isolates were recovered from health care workers and food product specimens were of agr Group I and isolates which were recovered from patients were of agr Group III. These differences were statistically significant (P=0.005). There was no statistical difference between the source of isolation of clinical samples of S. aureus and agr type. Conclusion: Agr Group I was predominant among health care workers and food product specimens in Gorgan, North of Iran, but in strains which were isolated from patients, agr Group III was predominant. Investigating the possible role of agr Group III in Staphylococcus aureus infection in future studies is recommended. s. aureus agr group genes pcr Medicine R Fatemeh Shakeri verfasserin aut Naeme Javid verfasserin aut Amir Ghaemi verfasserin aut Ezzat Allah Ghaemi verfasserin aut In Journal of Clinical and Diagnostic Research JCDR Research and Publications Private Limited, 2009 8(2014), 4, Seite DC07-DC09 (DE-627)789478048 (DE-600)2775283-5 0973709X nnns volume:8 year:2014 number:4 pages:DC07-DC09 https://doi.org/10.7860/JCDR/2014/6971.4219 kostenfrei https://doaj.org/article/ca8809ed1cf243f084a2c8a36e17ccd5 kostenfrei https://jcdr.net/articles/PDF/4219/6971_CE(Ra)_E(C)_F(P)_PF1(PAK)_PFA(H)_PFA2(AK).pdf kostenfrei https://doaj.org/toc/2249-782X Journal toc kostenfrei https://doaj.org/toc/0973-709X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2014 4 DC07-DC09
allfieldsSound	10.7860/JCDR/2014/6971.4219 doi (DE-627)DOAJ037782193 (DE-599)DOAJca8809ed1cf243f084a2c8a36e17ccd5 DE-627 ger DE-627 rakwb eng Meysam Hasannejad Bibalan verfasserin aut Accessory Gene Regulator Types of Staphylococcus aureus Isolated in Gorgan, North of Iran 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Staphylococcus aureus is a gram-positive bacterium that has remained a persistent pathogen, causing infections such as endocarditis, meningitis, and toxic shock syndrome in humans. The accessory gene regulator (agr) system of Staphylococcus aureus is responsible for controlling the expression of many genes that code for virulence factors. In this study, we assessed the S. aureus agr Group, based on their source of isolation, in Gorgan, North of Iran. Materials and Methods: DNA of 194 S. aureus isolates was extracted by lysozyme-phenol chloroform method, which included 85 clinical samples, 58 samples which were isolated from noses of health care workers and 51 cases which were obtained from food products in Gorgan, northern Iran. PCR-based assays were used to evaluate agr locus nucleotide polymorphism for the identification of agr specificity Group. Distributions of each agr Group were determined and comparison between different sources was assessed by X2 . A p-value of <0.05 was considered as significant. Results: The majority of isolates belonged to agr Group I (43.3%), followed by agr Group III (28.87%), agr Group II (22.68%), and agr Group IV (5.15%). In our study, a majority of S. aureus isolates were recovered from health care workers and food product specimens were of agr Group I and isolates which were recovered from patients were of agr Group III. These differences were statistically significant (P=0.005). There was no statistical difference between the source of isolation of clinical samples of S. aureus and agr type. Conclusion: Agr Group I was predominant among health care workers and food product specimens in Gorgan, North of Iran, but in strains which were isolated from patients, agr Group III was predominant. Investigating the possible role of agr Group III in Staphylococcus aureus infection in future studies is recommended. s. aureus agr group genes pcr Medicine R Fatemeh Shakeri verfasserin aut Naeme Javid verfasserin aut Amir Ghaemi verfasserin aut Ezzat Allah Ghaemi verfasserin aut In Journal of Clinical and Diagnostic Research JCDR Research and Publications Private Limited, 2009 8(2014), 4, Seite DC07-DC09 (DE-627)789478048 (DE-600)2775283-5 0973709X nnns volume:8 year:2014 number:4 pages:DC07-DC09 https://doi.org/10.7860/JCDR/2014/6971.4219 kostenfrei https://doaj.org/article/ca8809ed1cf243f084a2c8a36e17ccd5 kostenfrei https://jcdr.net/articles/PDF/4219/6971_CE(Ra)_E(C)_F(P)_PF1(PAK)_PFA(H)_PFA2(AK).pdf kostenfrei https://doaj.org/toc/2249-782X Journal toc kostenfrei https://doaj.org/toc/0973-709X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2014 4 DC07-DC09
language	English
source	In Journal of Clinical and Diagnostic Research 8(2014), 4, Seite DC07-DC09 volume:8 year:2014 number:4 pages:DC07-DC09
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authorswithroles_txt_mv	Meysam Hasannejad Bibalan @@aut@@ Fatemeh Shakeri @@aut@@ Naeme Javid @@aut@@ Amir Ghaemi @@aut@@ Ezzat Allah Ghaemi @@aut@@
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author	Meysam Hasannejad Bibalan
spellingShingle	Meysam Hasannejad Bibalan misc s. aureus misc agr group genes misc pcr misc Medicine misc R Accessory Gene Regulator Types of Staphylococcus aureus Isolated in Gorgan, North of Iran
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topic_title	Accessory Gene Regulator Types of Staphylococcus aureus Isolated in Gorgan, North of Iran s. aureus agr group genes pcr
topic	misc s. aureus misc agr group genes misc pcr misc Medicine misc R
topic_unstemmed	misc s. aureus misc agr group genes misc pcr misc Medicine misc R
topic_browse	misc s. aureus misc agr group genes misc pcr misc Medicine misc R
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title	Accessory Gene Regulator Types of Staphylococcus aureus Isolated in Gorgan, North of Iran
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title_full	Accessory Gene Regulator Types of Staphylococcus aureus Isolated in Gorgan, North of Iran
author_sort	Meysam Hasannejad Bibalan
journal	Journal of Clinical and Diagnostic Research
journalStr	Journal of Clinical and Diagnostic Research
lang_code	eng
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author_browse	Meysam Hasannejad Bibalan Fatemeh Shakeri Naeme Javid Amir Ghaemi Ezzat Allah Ghaemi
container_volume	8
format_se	Elektronische Aufsätze
author-letter	Meysam Hasannejad Bibalan
doi_str_mv	10.7860/JCDR/2014/6971.4219
author2-role	verfasserin
title_sort	accessory gene regulator types of staphylococcus aureus isolated in gorgan, north of iran
title_auth	Accessory Gene Regulator Types of Staphylococcus aureus Isolated in Gorgan, North of Iran
abstract	Background: Staphylococcus aureus is a gram-positive bacterium that has remained a persistent pathogen, causing infections such as endocarditis, meningitis, and toxic shock syndrome in humans. The accessory gene regulator (agr) system of Staphylococcus aureus is responsible for controlling the expression of many genes that code for virulence factors. In this study, we assessed the S. aureus agr Group, based on their source of isolation, in Gorgan, North of Iran. Materials and Methods: DNA of 194 S. aureus isolates was extracted by lysozyme-phenol chloroform method, which included 85 clinical samples, 58 samples which were isolated from noses of health care workers and 51 cases which were obtained from food products in Gorgan, northern Iran. PCR-based assays were used to evaluate agr locus nucleotide polymorphism for the identification of agr specificity Group. Distributions of each agr Group were determined and comparison between different sources was assessed by X2 . A p-value of <0.05 was considered as significant. Results: The majority of isolates belonged to agr Group I (43.3%), followed by agr Group III (28.87%), agr Group II (22.68%), and agr Group IV (5.15%). In our study, a majority of S. aureus isolates were recovered from health care workers and food product specimens were of agr Group I and isolates which were recovered from patients were of agr Group III. These differences were statistically significant (P=0.005). There was no statistical difference between the source of isolation of clinical samples of S. aureus and agr type. Conclusion: Agr Group I was predominant among health care workers and food product specimens in Gorgan, North of Iran, but in strains which were isolated from patients, agr Group III was predominant. Investigating the possible role of agr Group III in Staphylococcus aureus infection in future studies is recommended.
abstractGer	Background: Staphylococcus aureus is a gram-positive bacterium that has remained a persistent pathogen, causing infections such as endocarditis, meningitis, and toxic shock syndrome in humans. The accessory gene regulator (agr) system of Staphylococcus aureus is responsible for controlling the expression of many genes that code for virulence factors. In this study, we assessed the S. aureus agr Group, based on their source of isolation, in Gorgan, North of Iran. Materials and Methods: DNA of 194 S. aureus isolates was extracted by lysozyme-phenol chloroform method, which included 85 clinical samples, 58 samples which were isolated from noses of health care workers and 51 cases which were obtained from food products in Gorgan, northern Iran. PCR-based assays were used to evaluate agr locus nucleotide polymorphism for the identification of agr specificity Group. Distributions of each agr Group were determined and comparison between different sources was assessed by X2 . A p-value of <0.05 was considered as significant. Results: The majority of isolates belonged to agr Group I (43.3%), followed by agr Group III (28.87%), agr Group II (22.68%), and agr Group IV (5.15%). In our study, a majority of S. aureus isolates were recovered from health care workers and food product specimens were of agr Group I and isolates which were recovered from patients were of agr Group III. These differences were statistically significant (P=0.005). There was no statistical difference between the source of isolation of clinical samples of S. aureus and agr type. Conclusion: Agr Group I was predominant among health care workers and food product specimens in Gorgan, North of Iran, but in strains which were isolated from patients, agr Group III was predominant. Investigating the possible role of agr Group III in Staphylococcus aureus infection in future studies is recommended.
abstract_unstemmed	Background: Staphylococcus aureus is a gram-positive bacterium that has remained a persistent pathogen, causing infections such as endocarditis, meningitis, and toxic shock syndrome in humans. The accessory gene regulator (agr) system of Staphylococcus aureus is responsible for controlling the expression of many genes that code for virulence factors. In this study, we assessed the S. aureus agr Group, based on their source of isolation, in Gorgan, North of Iran. Materials and Methods: DNA of 194 S. aureus isolates was extracted by lysozyme-phenol chloroform method, which included 85 clinical samples, 58 samples which were isolated from noses of health care workers and 51 cases which were obtained from food products in Gorgan, northern Iran. PCR-based assays were used to evaluate agr locus nucleotide polymorphism for the identification of agr specificity Group. Distributions of each agr Group were determined and comparison between different sources was assessed by X2 . A p-value of <0.05 was considered as significant. Results: The majority of isolates belonged to agr Group I (43.3%), followed by agr Group III (28.87%), agr Group II (22.68%), and agr Group IV (5.15%). In our study, a majority of S. aureus isolates were recovered from health care workers and food product specimens were of agr Group I and isolates which were recovered from patients were of agr Group III. These differences were statistically significant (P=0.005). There was no statistical difference between the source of isolation of clinical samples of S. aureus and agr type. Conclusion: Agr Group I was predominant among health care workers and food product specimens in Gorgan, North of Iran, but in strains which were isolated from patients, agr Group III was predominant. Investigating the possible role of agr Group III in Staphylococcus aureus infection in future studies is recommended.
collection_details	GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700
container_issue	4
title_short	Accessory Gene Regulator Types of Staphylococcus aureus Isolated in Gorgan, North of Iran
url	https://doi.org/10.7860/JCDR/2014/6971.4219 https://doaj.org/article/ca8809ed1cf243f084a2c8a36e17ccd5 https://jcdr.net/articles/PDF/4219/6971_CE(Ra)_E(C)_F(P)_PF1(PAK)_PFA(H)_PFA2(AK).pdf https://doaj.org/toc/2249-782X https://doaj.org/toc/0973-709X
remote_bool	true
author2	Fatemeh Shakeri Naeme Javid Amir Ghaemi Ezzat Allah Ghaemi
author2Str	Fatemeh Shakeri Naeme Javid Amir Ghaemi Ezzat Allah Ghaemi
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doi_str	10.7860/JCDR/2014/6971.4219
up_date	2024-07-03T14:05:35.825Z
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