The clinico-radiological profile of obliterative bronchiolitis in a tertiary care center

Background: Obliterative bronchiolitis (OB) forms a major proportion of chronic airway diseases (CADs). OB is often misdiagnosed and included under the umbrella term 'chronic obstructive pulmonary disease'. We set out to identify the proportion of OB cases among the CADs and study the clin...
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Autor*in:	H S Suhas [verfasserIn] Ketaki Utpat [verfasserIn] Unnati Desai [verfasserIn] Jyotsna M Joshi [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2019

Schlagwörter:	Chronic airway diseases mosaic attenuation obliterative bronchiolitis

Übergeordnetes Werk:	In: Lung India - Wolters Kluwer Medknow Publications, 2009, 36(2019), 4, Seite 313-318
Übergeordnetes Werk:	volume:36 ; year:2019 ; number:4 ; pages:313-318

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.4103/lungindia.lungindia_499_18

Katalog-ID:	DOAJ03801677X

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520			\|a Background: Obliterative bronchiolitis (OB) forms a major proportion of chronic airway diseases (CADs). OB is often misdiagnosed and included under the umbrella term 'chronic obstructive pulmonary disease'. We set out to identify the proportion of OB cases among the CADs and study the clinical profile of OB. Materials and Methods: This prospective, observational study noted all patients with Chronic airway obstruction (CAO), of which patients with OB were included and the clinical profile was studied. Data were subjected to statistical analysis. Results: Five hundred patients with CAO were noted in the study period, of which 115 patients were found to be OB amounting to a prevalence of 23%. The mean age of presentation was 51.8 years (standard deviation 12.1) with a male–female ratio of 1:1. The most common etiology for OB was as sequelae to past treated pulmonary tuberculosis (PTB) seen in 82 patients (71%) of cases. Dyspnea in 114 patients (99%) and productive cough in 110 patients (95%) were the predominant symptoms. Postexercise desaturation was seen in all 115 patients (100%). Forty-six patients (43%) presented with either Type 1 or Type 2 respiratory failure. Spirometry showed obstructive pattern in 68 patients (59%) with forced expiratory volume in 1 s/forced vital capacity (FEV1/FVC) ratio of <70% and FEV1 <70% postbronchodilator and mixed pattern in 47 patients (41%) with a reduction in both FEV1 and FVC and normal FEV1/FVC ratio. There was the presence of mosaic attenuation on high-resolution computerized tomography (HRCT) of the chest with expiratory scans in all 115 patients (100%). Pulmonary hypertension was documented in 109 patients (95%). Conclusion: OB is one of the major causes of CAO. HRCT of the chest with expiratory scans plays a important role in the diagnosis. Early diagnosis can prevent irrevocable complications.
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allfields	10.4103/lungindia.lungindia_499_18 doi (DE-627)DOAJ03801677X (DE-599)DOAJca06d9ec49c74c5ea285371a7fcb0cce DE-627 ger DE-627 rakwb eng RC705-779 H S Suhas verfasserin aut The clinico-radiological profile of obliterative bronchiolitis in a tertiary care center 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Obliterative bronchiolitis (OB) forms a major proportion of chronic airway diseases (CADs). OB is often misdiagnosed and included under the umbrella term 'chronic obstructive pulmonary disease'. We set out to identify the proportion of OB cases among the CADs and study the clinical profile of OB. Materials and Methods: This prospective, observational study noted all patients with Chronic airway obstruction (CAO), of which patients with OB were included and the clinical profile was studied. Data were subjected to statistical analysis. Results: Five hundred patients with CAO were noted in the study period, of which 115 patients were found to be OB amounting to a prevalence of 23%. The mean age of presentation was 51.8 years (standard deviation 12.1) with a male–female ratio of 1:1. The most common etiology for OB was as sequelae to past treated pulmonary tuberculosis (PTB) seen in 82 patients (71%) of cases. Dyspnea in 114 patients (99%) and productive cough in 110 patients (95%) were the predominant symptoms. Postexercise desaturation was seen in all 115 patients (100%). Forty-six patients (43%) presented with either Type 1 or Type 2 respiratory failure. Spirometry showed obstructive pattern in 68 patients (59%) with forced expiratory volume in 1 s/forced vital capacity (FEV1/FVC) ratio of <70% and FEV1 <70% postbronchodilator and mixed pattern in 47 patients (41%) with a reduction in both FEV1 and FVC and normal FEV1/FVC ratio. There was the presence of mosaic attenuation on high-resolution computerized tomography (HRCT) of the chest with expiratory scans in all 115 patients (100%). Pulmonary hypertension was documented in 109 patients (95%). Conclusion: OB is one of the major causes of CAO. HRCT of the chest with expiratory scans plays a important role in the diagnosis. Early diagnosis can prevent irrevocable complications. Chronic airway diseases mosaic attenuation obliterative bronchiolitis Diseases of the respiratory system Ketaki Utpat verfasserin aut Unnati Desai verfasserin aut Jyotsna M Joshi verfasserin aut In Lung India Wolters Kluwer Medknow Publications, 2009 36(2019), 4, Seite 313-318 (DE-627)558697895 (DE-600)2410801-7 0974598X nnns volume:36 year:2019 number:4 pages:313-318 https://doi.org/10.4103/lungindia.lungindia_499_18 kostenfrei https://doaj.org/article/ca06d9ec49c74c5ea285371a7fcb0cce kostenfrei http://www.lungindia.com/article.asp?issn=0970-2113;year=2019;volume=36;issue=4;spage=313;epage=318;aulast=Suhas kostenfrei https://doaj.org/toc/0970-2113 Journal toc kostenfrei https://doaj.org/toc/0974-598X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 36 2019 4 313-318
spelling	10.4103/lungindia.lungindia_499_18 doi (DE-627)DOAJ03801677X (DE-599)DOAJca06d9ec49c74c5ea285371a7fcb0cce DE-627 ger DE-627 rakwb eng RC705-779 H S Suhas verfasserin aut The clinico-radiological profile of obliterative bronchiolitis in a tertiary care center 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Obliterative bronchiolitis (OB) forms a major proportion of chronic airway diseases (CADs). OB is often misdiagnosed and included under the umbrella term 'chronic obstructive pulmonary disease'. We set out to identify the proportion of OB cases among the CADs and study the clinical profile of OB. Materials and Methods: This prospective, observational study noted all patients with Chronic airway obstruction (CAO), of which patients with OB were included and the clinical profile was studied. Data were subjected to statistical analysis. Results: Five hundred patients with CAO were noted in the study period, of which 115 patients were found to be OB amounting to a prevalence of 23%. The mean age of presentation was 51.8 years (standard deviation 12.1) with a male–female ratio of 1:1. The most common etiology for OB was as sequelae to past treated pulmonary tuberculosis (PTB) seen in 82 patients (71%) of cases. Dyspnea in 114 patients (99%) and productive cough in 110 patients (95%) were the predominant symptoms. Postexercise desaturation was seen in all 115 patients (100%). Forty-six patients (43%) presented with either Type 1 or Type 2 respiratory failure. Spirometry showed obstructive pattern in 68 patients (59%) with forced expiratory volume in 1 s/forced vital capacity (FEV1/FVC) ratio of <70% and FEV1 <70% postbronchodilator and mixed pattern in 47 patients (41%) with a reduction in both FEV1 and FVC and normal FEV1/FVC ratio. There was the presence of mosaic attenuation on high-resolution computerized tomography (HRCT) of the chest with expiratory scans in all 115 patients (100%). Pulmonary hypertension was documented in 109 patients (95%). Conclusion: OB is one of the major causes of CAO. HRCT of the chest with expiratory scans plays a important role in the diagnosis. Early diagnosis can prevent irrevocable complications. Chronic airway diseases mosaic attenuation obliterative bronchiolitis Diseases of the respiratory system Ketaki Utpat verfasserin aut Unnati Desai verfasserin aut Jyotsna M Joshi verfasserin aut In Lung India Wolters Kluwer Medknow Publications, 2009 36(2019), 4, Seite 313-318 (DE-627)558697895 (DE-600)2410801-7 0974598X nnns volume:36 year:2019 number:4 pages:313-318 https://doi.org/10.4103/lungindia.lungindia_499_18 kostenfrei https://doaj.org/article/ca06d9ec49c74c5ea285371a7fcb0cce kostenfrei http://www.lungindia.com/article.asp?issn=0970-2113;year=2019;volume=36;issue=4;spage=313;epage=318;aulast=Suhas kostenfrei https://doaj.org/toc/0970-2113 Journal toc kostenfrei https://doaj.org/toc/0974-598X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 36 2019 4 313-318
allfields_unstemmed	10.4103/lungindia.lungindia_499_18 doi (DE-627)DOAJ03801677X (DE-599)DOAJca06d9ec49c74c5ea285371a7fcb0cce DE-627 ger DE-627 rakwb eng RC705-779 H S Suhas verfasserin aut The clinico-radiological profile of obliterative bronchiolitis in a tertiary care center 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Obliterative bronchiolitis (OB) forms a major proportion of chronic airway diseases (CADs). OB is often misdiagnosed and included under the umbrella term 'chronic obstructive pulmonary disease'. We set out to identify the proportion of OB cases among the CADs and study the clinical profile of OB. Materials and Methods: This prospective, observational study noted all patients with Chronic airway obstruction (CAO), of which patients with OB were included and the clinical profile was studied. Data were subjected to statistical analysis. Results: Five hundred patients with CAO were noted in the study period, of which 115 patients were found to be OB amounting to a prevalence of 23%. The mean age of presentation was 51.8 years (standard deviation 12.1) with a male–female ratio of 1:1. The most common etiology for OB was as sequelae to past treated pulmonary tuberculosis (PTB) seen in 82 patients (71%) of cases. Dyspnea in 114 patients (99%) and productive cough in 110 patients (95%) were the predominant symptoms. Postexercise desaturation was seen in all 115 patients (100%). Forty-six patients (43%) presented with either Type 1 or Type 2 respiratory failure. Spirometry showed obstructive pattern in 68 patients (59%) with forced expiratory volume in 1 s/forced vital capacity (FEV1/FVC) ratio of <70% and FEV1 <70% postbronchodilator and mixed pattern in 47 patients (41%) with a reduction in both FEV1 and FVC and normal FEV1/FVC ratio. There was the presence of mosaic attenuation on high-resolution computerized tomography (HRCT) of the chest with expiratory scans in all 115 patients (100%). Pulmonary hypertension was documented in 109 patients (95%). Conclusion: OB is one of the major causes of CAO. HRCT of the chest with expiratory scans plays a important role in the diagnosis. Early diagnosis can prevent irrevocable complications. Chronic airway diseases mosaic attenuation obliterative bronchiolitis Diseases of the respiratory system Ketaki Utpat verfasserin aut Unnati Desai verfasserin aut Jyotsna M Joshi verfasserin aut In Lung India Wolters Kluwer Medknow Publications, 2009 36(2019), 4, Seite 313-318 (DE-627)558697895 (DE-600)2410801-7 0974598X nnns volume:36 year:2019 number:4 pages:313-318 https://doi.org/10.4103/lungindia.lungindia_499_18 kostenfrei https://doaj.org/article/ca06d9ec49c74c5ea285371a7fcb0cce kostenfrei http://www.lungindia.com/article.asp?issn=0970-2113;year=2019;volume=36;issue=4;spage=313;epage=318;aulast=Suhas kostenfrei https://doaj.org/toc/0970-2113 Journal toc kostenfrei https://doaj.org/toc/0974-598X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 36 2019 4 313-318
allfieldsGer	10.4103/lungindia.lungindia_499_18 doi (DE-627)DOAJ03801677X (DE-599)DOAJca06d9ec49c74c5ea285371a7fcb0cce DE-627 ger DE-627 rakwb eng RC705-779 H S Suhas verfasserin aut The clinico-radiological profile of obliterative bronchiolitis in a tertiary care center 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Obliterative bronchiolitis (OB) forms a major proportion of chronic airway diseases (CADs). OB is often misdiagnosed and included under the umbrella term 'chronic obstructive pulmonary disease'. We set out to identify the proportion of OB cases among the CADs and study the clinical profile of OB. Materials and Methods: This prospective, observational study noted all patients with Chronic airway obstruction (CAO), of which patients with OB were included and the clinical profile was studied. Data were subjected to statistical analysis. Results: Five hundred patients with CAO were noted in the study period, of which 115 patients were found to be OB amounting to a prevalence of 23%. The mean age of presentation was 51.8 years (standard deviation 12.1) with a male–female ratio of 1:1. The most common etiology for OB was as sequelae to past treated pulmonary tuberculosis (PTB) seen in 82 patients (71%) of cases. Dyspnea in 114 patients (99%) and productive cough in 110 patients (95%) were the predominant symptoms. Postexercise desaturation was seen in all 115 patients (100%). Forty-six patients (43%) presented with either Type 1 or Type 2 respiratory failure. Spirometry showed obstructive pattern in 68 patients (59%) with forced expiratory volume in 1 s/forced vital capacity (FEV1/FVC) ratio of <70% and FEV1 <70% postbronchodilator and mixed pattern in 47 patients (41%) with a reduction in both FEV1 and FVC and normal FEV1/FVC ratio. There was the presence of mosaic attenuation on high-resolution computerized tomography (HRCT) of the chest with expiratory scans in all 115 patients (100%). Pulmonary hypertension was documented in 109 patients (95%). Conclusion: OB is one of the major causes of CAO. HRCT of the chest with expiratory scans plays a important role in the diagnosis. Early diagnosis can prevent irrevocable complications. Chronic airway diseases mosaic attenuation obliterative bronchiolitis Diseases of the respiratory system Ketaki Utpat verfasserin aut Unnati Desai verfasserin aut Jyotsna M Joshi verfasserin aut In Lung India Wolters Kluwer Medknow Publications, 2009 36(2019), 4, Seite 313-318 (DE-627)558697895 (DE-600)2410801-7 0974598X nnns volume:36 year:2019 number:4 pages:313-318 https://doi.org/10.4103/lungindia.lungindia_499_18 kostenfrei https://doaj.org/article/ca06d9ec49c74c5ea285371a7fcb0cce kostenfrei http://www.lungindia.com/article.asp?issn=0970-2113;year=2019;volume=36;issue=4;spage=313;epage=318;aulast=Suhas kostenfrei https://doaj.org/toc/0970-2113 Journal toc kostenfrei https://doaj.org/toc/0974-598X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 36 2019 4 313-318
allfieldsSound	10.4103/lungindia.lungindia_499_18 doi (DE-627)DOAJ03801677X (DE-599)DOAJca06d9ec49c74c5ea285371a7fcb0cce DE-627 ger DE-627 rakwb eng RC705-779 H S Suhas verfasserin aut The clinico-radiological profile of obliterative bronchiolitis in a tertiary care center 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Obliterative bronchiolitis (OB) forms a major proportion of chronic airway diseases (CADs). OB is often misdiagnosed and included under the umbrella term 'chronic obstructive pulmonary disease'. We set out to identify the proportion of OB cases among the CADs and study the clinical profile of OB. Materials and Methods: This prospective, observational study noted all patients with Chronic airway obstruction (CAO), of which patients with OB were included and the clinical profile was studied. Data were subjected to statistical analysis. Results: Five hundred patients with CAO were noted in the study period, of which 115 patients were found to be OB amounting to a prevalence of 23%. The mean age of presentation was 51.8 years (standard deviation 12.1) with a male–female ratio of 1:1. The most common etiology for OB was as sequelae to past treated pulmonary tuberculosis (PTB) seen in 82 patients (71%) of cases. Dyspnea in 114 patients (99%) and productive cough in 110 patients (95%) were the predominant symptoms. Postexercise desaturation was seen in all 115 patients (100%). Forty-six patients (43%) presented with either Type 1 or Type 2 respiratory failure. Spirometry showed obstructive pattern in 68 patients (59%) with forced expiratory volume in 1 s/forced vital capacity (FEV1/FVC) ratio of <70% and FEV1 <70% postbronchodilator and mixed pattern in 47 patients (41%) with a reduction in both FEV1 and FVC and normal FEV1/FVC ratio. There was the presence of mosaic attenuation on high-resolution computerized tomography (HRCT) of the chest with expiratory scans in all 115 patients (100%). Pulmonary hypertension was documented in 109 patients (95%). Conclusion: OB is one of the major causes of CAO. HRCT of the chest with expiratory scans plays a important role in the diagnosis. Early diagnosis can prevent irrevocable complications. Chronic airway diseases mosaic attenuation obliterative bronchiolitis Diseases of the respiratory system Ketaki Utpat verfasserin aut Unnati Desai verfasserin aut Jyotsna M Joshi verfasserin aut In Lung India Wolters Kluwer Medknow Publications, 2009 36(2019), 4, Seite 313-318 (DE-627)558697895 (DE-600)2410801-7 0974598X nnns volume:36 year:2019 number:4 pages:313-318 https://doi.org/10.4103/lungindia.lungindia_499_18 kostenfrei https://doaj.org/article/ca06d9ec49c74c5ea285371a7fcb0cce kostenfrei http://www.lungindia.com/article.asp?issn=0970-2113;year=2019;volume=36;issue=4;spage=313;epage=318;aulast=Suhas kostenfrei https://doaj.org/toc/0970-2113 Journal toc kostenfrei https://doaj.org/toc/0974-598X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 36 2019 4 313-318
language	English
source	In Lung India 36(2019), 4, Seite 313-318 volume:36 year:2019 number:4 pages:313-318
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topic_facet	Chronic airway diseases mosaic attenuation obliterative bronchiolitis Diseases of the respiratory system
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authorswithroles_txt_mv	H S Suhas @@aut@@ Ketaki Utpat @@aut@@ Unnati Desai @@aut@@ Jyotsna M Joshi @@aut@@
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spellingShingle	H S Suhas misc RC705-779 misc Chronic airway diseases misc mosaic attenuation misc obliterative bronchiolitis misc Diseases of the respiratory system The clinico-radiological profile of obliterative bronchiolitis in a tertiary care center
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topic_title	RC705-779 The clinico-radiological profile of obliterative bronchiolitis in a tertiary care center Chronic airway diseases mosaic attenuation obliterative bronchiolitis
topic	misc RC705-779 misc Chronic airway diseases misc mosaic attenuation misc obliterative bronchiolitis misc Diseases of the respiratory system
topic_unstemmed	misc RC705-779 misc Chronic airway diseases misc mosaic attenuation misc obliterative bronchiolitis misc Diseases of the respiratory system
topic_browse	misc RC705-779 misc Chronic airway diseases misc mosaic attenuation misc obliterative bronchiolitis misc Diseases of the respiratory system
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title	The clinico-radiological profile of obliterative bronchiolitis in a tertiary care center
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title_full	The clinico-radiological profile of obliterative bronchiolitis in a tertiary care center
author_sort	H S Suhas
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author_browse	H S Suhas Ketaki Utpat Unnati Desai Jyotsna M Joshi
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doi_str_mv	10.4103/lungindia.lungindia_499_18
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title_sort	clinico-radiological profile of obliterative bronchiolitis in a tertiary care center
callnumber	RC705-779
title_auth	The clinico-radiological profile of obliterative bronchiolitis in a tertiary care center
abstract	Background: Obliterative bronchiolitis (OB) forms a major proportion of chronic airway diseases (CADs). OB is often misdiagnosed and included under the umbrella term 'chronic obstructive pulmonary disease'. We set out to identify the proportion of OB cases among the CADs and study the clinical profile of OB. Materials and Methods: This prospective, observational study noted all patients with Chronic airway obstruction (CAO), of which patients with OB were included and the clinical profile was studied. Data were subjected to statistical analysis. Results: Five hundred patients with CAO were noted in the study period, of which 115 patients were found to be OB amounting to a prevalence of 23%. The mean age of presentation was 51.8 years (standard deviation 12.1) with a male–female ratio of 1:1. The most common etiology for OB was as sequelae to past treated pulmonary tuberculosis (PTB) seen in 82 patients (71%) of cases. Dyspnea in 114 patients (99%) and productive cough in 110 patients (95%) were the predominant symptoms. Postexercise desaturation was seen in all 115 patients (100%). Forty-six patients (43%) presented with either Type 1 or Type 2 respiratory failure. Spirometry showed obstructive pattern in 68 patients (59%) with forced expiratory volume in 1 s/forced vital capacity (FEV1/FVC) ratio of <70% and FEV1 <70% postbronchodilator and mixed pattern in 47 patients (41%) with a reduction in both FEV1 and FVC and normal FEV1/FVC ratio. There was the presence of mosaic attenuation on high-resolution computerized tomography (HRCT) of the chest with expiratory scans in all 115 patients (100%). Pulmonary hypertension was documented in 109 patients (95%). Conclusion: OB is one of the major causes of CAO. HRCT of the chest with expiratory scans plays a important role in the diagnosis. Early diagnosis can prevent irrevocable complications.
abstractGer	Background: Obliterative bronchiolitis (OB) forms a major proportion of chronic airway diseases (CADs). OB is often misdiagnosed and included under the umbrella term 'chronic obstructive pulmonary disease'. We set out to identify the proportion of OB cases among the CADs and study the clinical profile of OB. Materials and Methods: This prospective, observational study noted all patients with Chronic airway obstruction (CAO), of which patients with OB were included and the clinical profile was studied. Data were subjected to statistical analysis. Results: Five hundred patients with CAO were noted in the study period, of which 115 patients were found to be OB amounting to a prevalence of 23%. The mean age of presentation was 51.8 years (standard deviation 12.1) with a male–female ratio of 1:1. The most common etiology for OB was as sequelae to past treated pulmonary tuberculosis (PTB) seen in 82 patients (71%) of cases. Dyspnea in 114 patients (99%) and productive cough in 110 patients (95%) were the predominant symptoms. Postexercise desaturation was seen in all 115 patients (100%). Forty-six patients (43%) presented with either Type 1 or Type 2 respiratory failure. Spirometry showed obstructive pattern in 68 patients (59%) with forced expiratory volume in 1 s/forced vital capacity (FEV1/FVC) ratio of <70% and FEV1 <70% postbronchodilator and mixed pattern in 47 patients (41%) with a reduction in both FEV1 and FVC and normal FEV1/FVC ratio. There was the presence of mosaic attenuation on high-resolution computerized tomography (HRCT) of the chest with expiratory scans in all 115 patients (100%). Pulmonary hypertension was documented in 109 patients (95%). Conclusion: OB is one of the major causes of CAO. HRCT of the chest with expiratory scans plays a important role in the diagnosis. Early diagnosis can prevent irrevocable complications.
abstract_unstemmed	Background: Obliterative bronchiolitis (OB) forms a major proportion of chronic airway diseases (CADs). OB is often misdiagnosed and included under the umbrella term 'chronic obstructive pulmonary disease'. We set out to identify the proportion of OB cases among the CADs and study the clinical profile of OB. Materials and Methods: This prospective, observational study noted all patients with Chronic airway obstruction (CAO), of which patients with OB were included and the clinical profile was studied. Data were subjected to statistical analysis. Results: Five hundred patients with CAO were noted in the study period, of which 115 patients were found to be OB amounting to a prevalence of 23%. The mean age of presentation was 51.8 years (standard deviation 12.1) with a male–female ratio of 1:1. The most common etiology for OB was as sequelae to past treated pulmonary tuberculosis (PTB) seen in 82 patients (71%) of cases. Dyspnea in 114 patients (99%) and productive cough in 110 patients (95%) were the predominant symptoms. Postexercise desaturation was seen in all 115 patients (100%). Forty-six patients (43%) presented with either Type 1 or Type 2 respiratory failure. Spirometry showed obstructive pattern in 68 patients (59%) with forced expiratory volume in 1 s/forced vital capacity (FEV1/FVC) ratio of <70% and FEV1 <70% postbronchodilator and mixed pattern in 47 patients (41%) with a reduction in both FEV1 and FVC and normal FEV1/FVC ratio. There was the presence of mosaic attenuation on high-resolution computerized tomography (HRCT) of the chest with expiratory scans in all 115 patients (100%). Pulmonary hypertension was documented in 109 patients (95%). Conclusion: OB is one of the major causes of CAO. HRCT of the chest with expiratory scans plays a important role in the diagnosis. Early diagnosis can prevent irrevocable complications.
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title_short	The clinico-radiological profile of obliterative bronchiolitis in a tertiary care center
url	https://doi.org/10.4103/lungindia.lungindia_499_18 https://doaj.org/article/ca06d9ec49c74c5ea285371a7fcb0cce http://www.lungindia.com/article.asp?issn=0970-2113;year=2019;volume=36;issue=4;spage=313;epage=318;aulast=Suhas https://doaj.org/toc/0970-2113 https://doaj.org/toc/0974-598X
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up_date	2024-07-03T15:30:55.086Z
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