Repeat hepatectomy for recurrent hepatocellular carcinoma: a local experience and a systematic review

<p<Abstract</p< <p<Background</p< <p<This study aimed to assess the efficacy and safety of repeat hepatectomy for recurrent hepatocellular carcinoma (HCC).</p< <p<Methods</p< <p<Thirty-seven patients who underwent a curative repeat hepatectomy in...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Tan Yunchang [verfasserIn] Yin Zhengfeng [verfasserIn] Li Bin [verfasserIn] Sui Chengjun [verfasserIn] Zhou Yanming [verfasserIn] Yang Jiamei [verfasserIn] Liu Zhenyu [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2010

Übergeordnetes Werk:	In: World Journal of Surgical Oncology - BMC, 2003, 8(2010), 1, p 55
Übergeordnetes Werk:	volume:8 ; year:2010 ; number:1, p 55

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1186/1477-7819-8-55

Katalog-ID:	DOAJ039017915

Internformat


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allfields	10.1186/1477-7819-8-55 doi (DE-627)DOAJ039017915 (DE-599)DOAJc3ffbc5c1c734804903491ea52ad75c8 DE-627 ger DE-627 rakwb eng RD1-811 RC254-282 Tan Yunchang verfasserin aut Repeat hepatectomy for recurrent hepatocellular carcinoma: a local experience and a systematic review 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <p<Abstract</p< <p<Background</p< <p<This study aimed to assess the efficacy and safety of repeat hepatectomy for recurrent hepatocellular carcinoma (HCC).</p< <p<Methods</p< <p<Thirty-seven patients who underwent a curative repeat hepatectomy in our hospital were retrospectively studied. An extensive database literature search was performed to obtain for all relevant studies.</p< <p<Results</p< <p<In our series, there were no perioperative deaths during repeat hepatectomy for recurrent HCC. Patients survival after repeat hepatectomy were similar to 429 patients undergoing initial hepatectomy. A computerized search of the Medline and PubMed databases found 29 retrospective studies providing relevant data in 1149 patients were included for appraisal and data extraction. After the repeat hepatectomy, postoperative morbidity ranged from 6.2% to 68.2% with a median per cohort of 23.5 per cent. There were 7 perioperative deaths (0.7 per cent of 993 for whom mortality data were provided). The overall median survival ranged from 21 to 61.5 months, with 1 -, 3 -, and 5-year survival of 69.0% to 100%, 21.0% to 87.0%, and 25.0% to 87.0%, respectively.</p< <p<Conclusions</p< <p<Repeat hepatectomy can be performed safely and is associated with long-term survival in a subset of patients with recurrent HCC. However, the findings have to be carefully interpreted due to the lower level of evidence. A randomized controlled study is needed to compare repeat hepatectomy and other modalities for recurrent HCC.</p< Surgery Neoplasms. Tumors. Oncology. Including cancer and carcinogens Yin Zhengfeng verfasserin aut Li Bin verfasserin aut Sui Chengjun verfasserin aut Zhou Yanming verfasserin aut Yang Jiamei verfasserin aut Liu Zhenyu verfasserin aut In World Journal of Surgical Oncology BMC, 2003 8(2010), 1, p 55 (DE-627)369082907 (DE-600)2118383-1 14777819 nnns volume:8 year:2010 number:1, p 55 https://doi.org/10.1186/1477-7819-8-55 kostenfrei https://doaj.org/article/c3ffbc5c1c734804903491ea52ad75c8 kostenfrei http://www.wjso.com/content/8/1/55 kostenfrei https://doaj.org/toc/1477-7819 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2010 1, p 55
spelling	10.1186/1477-7819-8-55 doi (DE-627)DOAJ039017915 (DE-599)DOAJc3ffbc5c1c734804903491ea52ad75c8 DE-627 ger DE-627 rakwb eng RD1-811 RC254-282 Tan Yunchang verfasserin aut Repeat hepatectomy for recurrent hepatocellular carcinoma: a local experience and a systematic review 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <p<Abstract</p< <p<Background</p< <p<This study aimed to assess the efficacy and safety of repeat hepatectomy for recurrent hepatocellular carcinoma (HCC).</p< <p<Methods</p< <p<Thirty-seven patients who underwent a curative repeat hepatectomy in our hospital were retrospectively studied. An extensive database literature search was performed to obtain for all relevant studies.</p< <p<Results</p< <p<In our series, there were no perioperative deaths during repeat hepatectomy for recurrent HCC. Patients survival after repeat hepatectomy were similar to 429 patients undergoing initial hepatectomy. A computerized search of the Medline and PubMed databases found 29 retrospective studies providing relevant data in 1149 patients were included for appraisal and data extraction. After the repeat hepatectomy, postoperative morbidity ranged from 6.2% to 68.2% with a median per cohort of 23.5 per cent. There were 7 perioperative deaths (0.7 per cent of 993 for whom mortality data were provided). The overall median survival ranged from 21 to 61.5 months, with 1 -, 3 -, and 5-year survival of 69.0% to 100%, 21.0% to 87.0%, and 25.0% to 87.0%, respectively.</p< <p<Conclusions</p< <p<Repeat hepatectomy can be performed safely and is associated with long-term survival in a subset of patients with recurrent HCC. However, the findings have to be carefully interpreted due to the lower level of evidence. A randomized controlled study is needed to compare repeat hepatectomy and other modalities for recurrent HCC.</p< Surgery Neoplasms. Tumors. Oncology. Including cancer and carcinogens Yin Zhengfeng verfasserin aut Li Bin verfasserin aut Sui Chengjun verfasserin aut Zhou Yanming verfasserin aut Yang Jiamei verfasserin aut Liu Zhenyu verfasserin aut In World Journal of Surgical Oncology BMC, 2003 8(2010), 1, p 55 (DE-627)369082907 (DE-600)2118383-1 14777819 nnns volume:8 year:2010 number:1, p 55 https://doi.org/10.1186/1477-7819-8-55 kostenfrei https://doaj.org/article/c3ffbc5c1c734804903491ea52ad75c8 kostenfrei http://www.wjso.com/content/8/1/55 kostenfrei https://doaj.org/toc/1477-7819 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2010 1, p 55
allfields_unstemmed	10.1186/1477-7819-8-55 doi (DE-627)DOAJ039017915 (DE-599)DOAJc3ffbc5c1c734804903491ea52ad75c8 DE-627 ger DE-627 rakwb eng RD1-811 RC254-282 Tan Yunchang verfasserin aut Repeat hepatectomy for recurrent hepatocellular carcinoma: a local experience and a systematic review 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <p<Abstract</p< <p<Background</p< <p<This study aimed to assess the efficacy and safety of repeat hepatectomy for recurrent hepatocellular carcinoma (HCC).</p< <p<Methods</p< <p<Thirty-seven patients who underwent a curative repeat hepatectomy in our hospital were retrospectively studied. An extensive database literature search was performed to obtain for all relevant studies.</p< <p<Results</p< <p<In our series, there were no perioperative deaths during repeat hepatectomy for recurrent HCC. Patients survival after repeat hepatectomy were similar to 429 patients undergoing initial hepatectomy. A computerized search of the Medline and PubMed databases found 29 retrospective studies providing relevant data in 1149 patients were included for appraisal and data extraction. After the repeat hepatectomy, postoperative morbidity ranged from 6.2% to 68.2% with a median per cohort of 23.5 per cent. There were 7 perioperative deaths (0.7 per cent of 993 for whom mortality data were provided). The overall median survival ranged from 21 to 61.5 months, with 1 -, 3 -, and 5-year survival of 69.0% to 100%, 21.0% to 87.0%, and 25.0% to 87.0%, respectively.</p< <p<Conclusions</p< <p<Repeat hepatectomy can be performed safely and is associated with long-term survival in a subset of patients with recurrent HCC. However, the findings have to be carefully interpreted due to the lower level of evidence. A randomized controlled study is needed to compare repeat hepatectomy and other modalities for recurrent HCC.</p< Surgery Neoplasms. Tumors. Oncology. Including cancer and carcinogens Yin Zhengfeng verfasserin aut Li Bin verfasserin aut Sui Chengjun verfasserin aut Zhou Yanming verfasserin aut Yang Jiamei verfasserin aut Liu Zhenyu verfasserin aut In World Journal of Surgical Oncology BMC, 2003 8(2010), 1, p 55 (DE-627)369082907 (DE-600)2118383-1 14777819 nnns volume:8 year:2010 number:1, p 55 https://doi.org/10.1186/1477-7819-8-55 kostenfrei https://doaj.org/article/c3ffbc5c1c734804903491ea52ad75c8 kostenfrei http://www.wjso.com/content/8/1/55 kostenfrei https://doaj.org/toc/1477-7819 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2010 1, p 55
allfieldsGer	10.1186/1477-7819-8-55 doi (DE-627)DOAJ039017915 (DE-599)DOAJc3ffbc5c1c734804903491ea52ad75c8 DE-627 ger DE-627 rakwb eng RD1-811 RC254-282 Tan Yunchang verfasserin aut Repeat hepatectomy for recurrent hepatocellular carcinoma: a local experience and a systematic review 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <p<Abstract</p< <p<Background</p< <p<This study aimed to assess the efficacy and safety of repeat hepatectomy for recurrent hepatocellular carcinoma (HCC).</p< <p<Methods</p< <p<Thirty-seven patients who underwent a curative repeat hepatectomy in our hospital were retrospectively studied. An extensive database literature search was performed to obtain for all relevant studies.</p< <p<Results</p< <p<In our series, there were no perioperative deaths during repeat hepatectomy for recurrent HCC. Patients survival after repeat hepatectomy were similar to 429 patients undergoing initial hepatectomy. A computerized search of the Medline and PubMed databases found 29 retrospective studies providing relevant data in 1149 patients were included for appraisal and data extraction. After the repeat hepatectomy, postoperative morbidity ranged from 6.2% to 68.2% with a median per cohort of 23.5 per cent. There were 7 perioperative deaths (0.7 per cent of 993 for whom mortality data were provided). The overall median survival ranged from 21 to 61.5 months, with 1 -, 3 -, and 5-year survival of 69.0% to 100%, 21.0% to 87.0%, and 25.0% to 87.0%, respectively.</p< <p<Conclusions</p< <p<Repeat hepatectomy can be performed safely and is associated with long-term survival in a subset of patients with recurrent HCC. However, the findings have to be carefully interpreted due to the lower level of evidence. A randomized controlled study is needed to compare repeat hepatectomy and other modalities for recurrent HCC.</p< Surgery Neoplasms. Tumors. Oncology. Including cancer and carcinogens Yin Zhengfeng verfasserin aut Li Bin verfasserin aut Sui Chengjun verfasserin aut Zhou Yanming verfasserin aut Yang Jiamei verfasserin aut Liu Zhenyu verfasserin aut In World Journal of Surgical Oncology BMC, 2003 8(2010), 1, p 55 (DE-627)369082907 (DE-600)2118383-1 14777819 nnns volume:8 year:2010 number:1, p 55 https://doi.org/10.1186/1477-7819-8-55 kostenfrei https://doaj.org/article/c3ffbc5c1c734804903491ea52ad75c8 kostenfrei http://www.wjso.com/content/8/1/55 kostenfrei https://doaj.org/toc/1477-7819 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2010 1, p 55
allfieldsSound	10.1186/1477-7819-8-55 doi (DE-627)DOAJ039017915 (DE-599)DOAJc3ffbc5c1c734804903491ea52ad75c8 DE-627 ger DE-627 rakwb eng RD1-811 RC254-282 Tan Yunchang verfasserin aut Repeat hepatectomy for recurrent hepatocellular carcinoma: a local experience and a systematic review 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <p<Abstract</p< <p<Background</p< <p<This study aimed to assess the efficacy and safety of repeat hepatectomy for recurrent hepatocellular carcinoma (HCC).</p< <p<Methods</p< <p<Thirty-seven patients who underwent a curative repeat hepatectomy in our hospital were retrospectively studied. An extensive database literature search was performed to obtain for all relevant studies.</p< <p<Results</p< <p<In our series, there were no perioperative deaths during repeat hepatectomy for recurrent HCC. Patients survival after repeat hepatectomy were similar to 429 patients undergoing initial hepatectomy. A computerized search of the Medline and PubMed databases found 29 retrospective studies providing relevant data in 1149 patients were included for appraisal and data extraction. After the repeat hepatectomy, postoperative morbidity ranged from 6.2% to 68.2% with a median per cohort of 23.5 per cent. There were 7 perioperative deaths (0.7 per cent of 993 for whom mortality data were provided). The overall median survival ranged from 21 to 61.5 months, with 1 -, 3 -, and 5-year survival of 69.0% to 100%, 21.0% to 87.0%, and 25.0% to 87.0%, respectively.</p< <p<Conclusions</p< <p<Repeat hepatectomy can be performed safely and is associated with long-term survival in a subset of patients with recurrent HCC. However, the findings have to be carefully interpreted due to the lower level of evidence. A randomized controlled study is needed to compare repeat hepatectomy and other modalities for recurrent HCC.</p< Surgery Neoplasms. Tumors. Oncology. Including cancer and carcinogens Yin Zhengfeng verfasserin aut Li Bin verfasserin aut Sui Chengjun verfasserin aut Zhou Yanming verfasserin aut Yang Jiamei verfasserin aut Liu Zhenyu verfasserin aut In World Journal of Surgical Oncology BMC, 2003 8(2010), 1, p 55 (DE-627)369082907 (DE-600)2118383-1 14777819 nnns volume:8 year:2010 number:1, p 55 https://doi.org/10.1186/1477-7819-8-55 kostenfrei https://doaj.org/article/c3ffbc5c1c734804903491ea52ad75c8 kostenfrei http://www.wjso.com/content/8/1/55 kostenfrei https://doaj.org/toc/1477-7819 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2010 1, p 55
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source	In World Journal of Surgical Oncology 8(2010), 1, p 55 volume:8 year:2010 number:1, p 55
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callnumber-first	R - Medicine
author	Tan Yunchang
spellingShingle	Tan Yunchang misc RD1-811 misc RC254-282 misc Surgery misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens Repeat hepatectomy for recurrent hepatocellular carcinoma: a local experience and a systematic review
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topic_title	RD1-811 RC254-282 Repeat hepatectomy for recurrent hepatocellular carcinoma: a local experience and a systematic review
topic	misc RD1-811 misc RC254-282 misc Surgery misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens
topic_unstemmed	misc RD1-811 misc RC254-282 misc Surgery misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens
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title	Repeat hepatectomy for recurrent hepatocellular carcinoma: a local experience and a systematic review
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title_full	Repeat hepatectomy for recurrent hepatocellular carcinoma: a local experience and a systematic review
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title_sort	repeat hepatectomy for recurrent hepatocellular carcinoma: a local experience and a systematic review
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title_auth	Repeat hepatectomy for recurrent hepatocellular carcinoma: a local experience and a systematic review
abstract	<p<Abstract</p< <p<Background</p< <p<This study aimed to assess the efficacy and safety of repeat hepatectomy for recurrent hepatocellular carcinoma (HCC).</p< <p<Methods</p< <p<Thirty-seven patients who underwent a curative repeat hepatectomy in our hospital were retrospectively studied. An extensive database literature search was performed to obtain for all relevant studies.</p< <p<Results</p< <p<In our series, there were no perioperative deaths during repeat hepatectomy for recurrent HCC. Patients survival after repeat hepatectomy were similar to 429 patients undergoing initial hepatectomy. A computerized search of the Medline and PubMed databases found 29 retrospective studies providing relevant data in 1149 patients were included for appraisal and data extraction. After the repeat hepatectomy, postoperative morbidity ranged from 6.2% to 68.2% with a median per cohort of 23.5 per cent. There were 7 perioperative deaths (0.7 per cent of 993 for whom mortality data were provided). The overall median survival ranged from 21 to 61.5 months, with 1 -, 3 -, and 5-year survival of 69.0% to 100%, 21.0% to 87.0%, and 25.0% to 87.0%, respectively.</p< <p<Conclusions</p< <p<Repeat hepatectomy can be performed safely and is associated with long-term survival in a subset of patients with recurrent HCC. However, the findings have to be carefully interpreted due to the lower level of evidence. A randomized controlled study is needed to compare repeat hepatectomy and other modalities for recurrent HCC.</p<
abstractGer	<p<Abstract</p< <p<Background</p< <p<This study aimed to assess the efficacy and safety of repeat hepatectomy for recurrent hepatocellular carcinoma (HCC).</p< <p<Methods</p< <p<Thirty-seven patients who underwent a curative repeat hepatectomy in our hospital were retrospectively studied. An extensive database literature search was performed to obtain for all relevant studies.</p< <p<Results</p< <p<In our series, there were no perioperative deaths during repeat hepatectomy for recurrent HCC. Patients survival after repeat hepatectomy were similar to 429 patients undergoing initial hepatectomy. A computerized search of the Medline and PubMed databases found 29 retrospective studies providing relevant data in 1149 patients were included for appraisal and data extraction. After the repeat hepatectomy, postoperative morbidity ranged from 6.2% to 68.2% with a median per cohort of 23.5 per cent. There were 7 perioperative deaths (0.7 per cent of 993 for whom mortality data were provided). The overall median survival ranged from 21 to 61.5 months, with 1 -, 3 -, and 5-year survival of 69.0% to 100%, 21.0% to 87.0%, and 25.0% to 87.0%, respectively.</p< <p<Conclusions</p< <p<Repeat hepatectomy can be performed safely and is associated with long-term survival in a subset of patients with recurrent HCC. However, the findings have to be carefully interpreted due to the lower level of evidence. A randomized controlled study is needed to compare repeat hepatectomy and other modalities for recurrent HCC.</p<
abstract_unstemmed	<p<Abstract</p< <p<Background</p< <p<This study aimed to assess the efficacy and safety of repeat hepatectomy for recurrent hepatocellular carcinoma (HCC).</p< <p<Methods</p< <p<Thirty-seven patients who underwent a curative repeat hepatectomy in our hospital were retrospectively studied. An extensive database literature search was performed to obtain for all relevant studies.</p< <p<Results</p< <p<In our series, there were no perioperative deaths during repeat hepatectomy for recurrent HCC. Patients survival after repeat hepatectomy were similar to 429 patients undergoing initial hepatectomy. A computerized search of the Medline and PubMed databases found 29 retrospective studies providing relevant data in 1149 patients were included for appraisal and data extraction. After the repeat hepatectomy, postoperative morbidity ranged from 6.2% to 68.2% with a median per cohort of 23.5 per cent. There were 7 perioperative deaths (0.7 per cent of 993 for whom mortality data were provided). The overall median survival ranged from 21 to 61.5 months, with 1 -, 3 -, and 5-year survival of 69.0% to 100%, 21.0% to 87.0%, and 25.0% to 87.0%, respectively.</p< <p<Conclusions</p< <p<Repeat hepatectomy can be performed safely and is associated with long-term survival in a subset of patients with recurrent HCC. However, the findings have to be carefully interpreted due to the lower level of evidence. A randomized controlled study is needed to compare repeat hepatectomy and other modalities for recurrent HCC.</p<
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title_short	Repeat hepatectomy for recurrent hepatocellular carcinoma: a local experience and a systematic review
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Repeat hepatectomy for recurrent hepatocellular carcinoma: a local experience and a systematic review

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