Characterizing cognitive aging of recognition memory and related processes in animal models and in humans

Analyses of complex behaviors across the lifespan of animals can reveal the brain regions that are impacted by the normal aging process, thereby, elucidating potential therapeutic targets. Recent data from rats, monkeys and humans converge, all indicating that recognition memory and complex visual...
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Gespeichert in:

Autor*in:	Carol A Barnes [verfasserIn] Sara N Burke [verfasserIn] L. eRyan [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2012

Schlagwörter:	Perception monkey rat perirhinal cortex medial temporal lobe

Übergeordnetes Werk:	In: Frontiers in Aging Neuroscience - Frontiers Media S.A., 2010, 4(2012)
Übergeordnetes Werk:	volume:4 ; year:2012

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3389/fnagi.2012.00015

Katalog-ID:	DOAJ039094979

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callnumber-first	R - Medicine
author	Carol A Barnes
spellingShingle	Carol A Barnes misc RC321-571 misc Perception misc monkey misc rat misc perirhinal cortex misc medial temporal lobe misc Neurosciences. Biological psychiatry. Neuropsychiatry Characterizing cognitive aging of recognition memory and related processes in animal models and in humans
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title	Characterizing cognitive aging of recognition memory and related processes in animal models and in humans
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title_auth	Characterizing cognitive aging of recognition memory and related processes in animal models and in humans
abstract	Analyses of complex behaviors across the lifespan of animals can reveal the brain regions that are impacted by the normal aging process, thereby, elucidating potential therapeutic targets. Recent data from rats, monkeys and humans converge, all indicating that recognition memory and complex visual perception are impaired in advanced age. These cognitive processes are also disrupted in animals with lesions of the perirhinal cortex, indicating that the the functional integrity of this structure is disrupted in old age. This current review summarizes these data, and highlights current methodologies for assessing perirhinal cortex-dependent behaviors across the lifespan.
abstractGer	Analyses of complex behaviors across the lifespan of animals can reveal the brain regions that are impacted by the normal aging process, thereby, elucidating potential therapeutic targets. Recent data from rats, monkeys and humans converge, all indicating that recognition memory and complex visual perception are impaired in advanced age. These cognitive processes are also disrupted in animals with lesions of the perirhinal cortex, indicating that the the functional integrity of this structure is disrupted in old age. This current review summarizes these data, and highlights current methodologies for assessing perirhinal cortex-dependent behaviors across the lifespan.
abstract_unstemmed	Analyses of complex behaviors across the lifespan of animals can reveal the brain regions that are impacted by the normal aging process, thereby, elucidating potential therapeutic targets. Recent data from rats, monkeys and humans converge, all indicating that recognition memory and complex visual perception are impaired in advanced age. These cognitive processes are also disrupted in animals with lesions of the perirhinal cortex, indicating that the the functional integrity of this structure is disrupted in old age. This current review summarizes these data, and highlights current methodologies for assessing perirhinal cortex-dependent behaviors across the lifespan.
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title_short	Characterizing cognitive aging of recognition memory and related processes in animal models and in humans
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up_date	2024-07-03T21:34:34.300Z
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