Leiomyosarcoma of the inferior vena cava: Radical surgery and vascular reconstruction

<p<Abstract</p< <p<Background</p< <p<Vascular leiomyosarcoma are rare tumors typically originating from the inferior vena cava (IVC). Due to nonspecific clinical signs most tumors are diagnosed at advanced stages. Complete surgical resection remains the only potential c...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Knoefel Wolfram T [verfasserIn] Poremba Christopher [verfasserIn] Raffel Andreas [verfasserIn] Rehders Alexander [verfasserIn] Alexander Andrea [verfasserIn] Eisenberger Claus F [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2009

Übergeordnetes Werk:	In: World Journal of Surgical Oncology - BMC, 2003, 7(2009), 1, p 56
Übergeordnetes Werk:	volume:7 ; year:2009 ; number:1, p 56

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1186/1477-7819-7-56

Katalog-ID:	DOAJ039103749

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allfieldsSound	10.1186/1477-7819-7-56 doi (DE-627)DOAJ039103749 (DE-599)DOAJae6bdd158da6462ba79617a00cff42cd DE-627 ger DE-627 rakwb eng RD1-811 RC254-282 Knoefel Wolfram T verfasserin aut Leiomyosarcoma of the inferior vena cava: Radical surgery and vascular reconstruction 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <p<Abstract</p< <p<Background</p< <p<Vascular leiomyosarcoma are rare tumors typically originating from the inferior vena cava (IVC). Due to nonspecific clinical signs most tumors are diagnosed at advanced stages. Complete surgical resection remains the only potential curative therapeutic option. Surgical strategy is particularly influenced by the level of the IVC affected. Due to the topographic relation to the renal veins level-II involvement of the IVC raises special surgical challenges with respect to the maintenance of venous outflow.</p< <p<Case presentation</p< <p<We herein report two cases of leiomyosarcoma of the IVC with successful en bloc resection and individualized caval reconstruction. One patient presented with a large intramural and intraluminal mass and received a complete circumferential resection. Reconstruction was performed by graft replacement of the caval segment affected. The other patient displayed a predominantly extraluminal tumor growth and underwent semicircumferential resection of the IVC including the confluence of the left renal vein. In this case vascular reconstruction was performed by cavoplasty and reinsertion of the left renal vein into the proximal portion of the IVC. Resection margins of both patients were tumor free and no clinical signs of venous insufficiency of the lower extremity occurred.</p< <p<Conclusion</p< <p<This paper presents two cases of successfully managed leiomyosarcomas of the vena cava and exemplifies two different options for vascular reconstruction in level II sarcomas and includes a thorough review of the literature.</p< Surgery Neoplasms. Tumors. Oncology. Including cancer and carcinogens Poremba Christopher verfasserin aut Raffel Andreas verfasserin aut Rehders Alexander verfasserin aut Alexander Andrea verfasserin aut Eisenberger Claus F verfasserin aut In World Journal of Surgical Oncology BMC, 2003 7(2009), 1, p 56 (DE-627)369082907 (DE-600)2118383-1 14777819 nnns volume:7 year:2009 number:1, p 56 https://doi.org/10.1186/1477-7819-7-56 kostenfrei https://doaj.org/article/ae6bdd158da6462ba79617a00cff42cd kostenfrei http://www.wjso.com/content/7/1/56 kostenfrei https://doaj.org/toc/1477-7819 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 7 2009 1, p 56
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callnumber-first	R - Medicine
author	Knoefel Wolfram T
spellingShingle	Knoefel Wolfram T misc RD1-811 misc RC254-282 misc Surgery misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens Leiomyosarcoma of the inferior vena cava: Radical surgery and vascular reconstruction
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topic_title	RD1-811 RC254-282 Leiomyosarcoma of the inferior vena cava: Radical surgery and vascular reconstruction
topic	misc RD1-811 misc RC254-282 misc Surgery misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens
topic_unstemmed	misc RD1-811 misc RC254-282 misc Surgery misc Neoplasms. Tumors. Oncology. Including cancer and carcinogens
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title	Leiomyosarcoma of the inferior vena cava: Radical surgery and vascular reconstruction
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title_full	Leiomyosarcoma of the inferior vena cava: Radical surgery and vascular reconstruction
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title_sort	leiomyosarcoma of the inferior vena cava: radical surgery and vascular reconstruction
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title_auth	Leiomyosarcoma of the inferior vena cava: Radical surgery and vascular reconstruction
abstract	<p<Abstract</p< <p<Background</p< <p<Vascular leiomyosarcoma are rare tumors typically originating from the inferior vena cava (IVC). Due to nonspecific clinical signs most tumors are diagnosed at advanced stages. Complete surgical resection remains the only potential curative therapeutic option. Surgical strategy is particularly influenced by the level of the IVC affected. Due to the topographic relation to the renal veins level-II involvement of the IVC raises special surgical challenges with respect to the maintenance of venous outflow.</p< <p<Case presentation</p< <p<We herein report two cases of leiomyosarcoma of the IVC with successful en bloc resection and individualized caval reconstruction. One patient presented with a large intramural and intraluminal mass and received a complete circumferential resection. Reconstruction was performed by graft replacement of the caval segment affected. The other patient displayed a predominantly extraluminal tumor growth and underwent semicircumferential resection of the IVC including the confluence of the left renal vein. In this case vascular reconstruction was performed by cavoplasty and reinsertion of the left renal vein into the proximal portion of the IVC. Resection margins of both patients were tumor free and no clinical signs of venous insufficiency of the lower extremity occurred.</p< <p<Conclusion</p< <p<This paper presents two cases of successfully managed leiomyosarcomas of the vena cava and exemplifies two different options for vascular reconstruction in level II sarcomas and includes a thorough review of the literature.</p<
abstractGer	<p<Abstract</p< <p<Background</p< <p<Vascular leiomyosarcoma are rare tumors typically originating from the inferior vena cava (IVC). Due to nonspecific clinical signs most tumors are diagnosed at advanced stages. Complete surgical resection remains the only potential curative therapeutic option. Surgical strategy is particularly influenced by the level of the IVC affected. Due to the topographic relation to the renal veins level-II involvement of the IVC raises special surgical challenges with respect to the maintenance of venous outflow.</p< <p<Case presentation</p< <p<We herein report two cases of leiomyosarcoma of the IVC with successful en bloc resection and individualized caval reconstruction. One patient presented with a large intramural and intraluminal mass and received a complete circumferential resection. Reconstruction was performed by graft replacement of the caval segment affected. The other patient displayed a predominantly extraluminal tumor growth and underwent semicircumferential resection of the IVC including the confluence of the left renal vein. In this case vascular reconstruction was performed by cavoplasty and reinsertion of the left renal vein into the proximal portion of the IVC. Resection margins of both patients were tumor free and no clinical signs of venous insufficiency of the lower extremity occurred.</p< <p<Conclusion</p< <p<This paper presents two cases of successfully managed leiomyosarcomas of the vena cava and exemplifies two different options for vascular reconstruction in level II sarcomas and includes a thorough review of the literature.</p<
abstract_unstemmed	<p<Abstract</p< <p<Background</p< <p<Vascular leiomyosarcoma are rare tumors typically originating from the inferior vena cava (IVC). Due to nonspecific clinical signs most tumors are diagnosed at advanced stages. Complete surgical resection remains the only potential curative therapeutic option. Surgical strategy is particularly influenced by the level of the IVC affected. Due to the topographic relation to the renal veins level-II involvement of the IVC raises special surgical challenges with respect to the maintenance of venous outflow.</p< <p<Case presentation</p< <p<We herein report two cases of leiomyosarcoma of the IVC with successful en bloc resection and individualized caval reconstruction. One patient presented with a large intramural and intraluminal mass and received a complete circumferential resection. Reconstruction was performed by graft replacement of the caval segment affected. The other patient displayed a predominantly extraluminal tumor growth and underwent semicircumferential resection of the IVC including the confluence of the left renal vein. In this case vascular reconstruction was performed by cavoplasty and reinsertion of the left renal vein into the proximal portion of the IVC. Resection margins of both patients were tumor free and no clinical signs of venous insufficiency of the lower extremity occurred.</p< <p<Conclusion</p< <p<This paper presents two cases of successfully managed leiomyosarcomas of the vena cava and exemplifies two different options for vascular reconstruction in level II sarcomas and includes a thorough review of the literature.</p<
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Leiomyosarcoma of the inferior vena cava: Radical surgery and vascular reconstruction

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