Antioxidant isolated from Schisandra propinqua (Wall.) Baill

Schisandra propinqua (Wall.) Baill.(Schisandraceae) is widely used as a Chinese folk medicine. In this study, activity-guided fractionation of the ethanol extract from the stem of Schisandra propinqua led to the isolation of four extracts. Subsequently, a neolignan 4,4-di(4-hydroxy-3-methoxyphenly)-...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	FENG HUANG [verfasserIn] LIJIA XU [verfasserIn] SHI GANGGANG [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2009

Schlagwörter:	antioxidant free radical lipid peroxidation Schisandra propinqua

Übergeordnetes Werk:	In: Biological Research - BMC, 2018, 42(2009), 3, Seite 351-356
Übergeordnetes Werk:	volume:42 ; year:2009 ; number:3 ; pages:351-356

Links:	Link aufrufen Link aufrufen Journal toc Journal toc

Katalog-ID:	DOAJ040490491

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520			\|a Schisandra propinqua (Wall.) Baill.(Schisandraceae) is widely used as a Chinese folk medicine. In this study, activity-guided fractionation of the ethanol extract from the stem of Schisandra propinqua led to the isolation of four extracts. Subsequently, a neolignan 4,4-di(4-hydroxy-3-methoxyphenly)-2,3-dimethylbutanol was isolated from the EtOAc part of the stem of Schisandra propinqua, the free radical scavenging activities of which were researched in vitro. The present work demonstrated that extracts and pure compound possessed scavenging activities to DPPH, superoxide anions and hydroxy radical, and could depress lipid peroxidation reaction induced by oxygen radical produced by the Fe2+/cysteine system in vitro. This suggests that the traditional application of Schisandra propinqua in China may be related to its antioxidant activities, and the EtOAc part of the stems of Schisandra propinqua can be utilized as an effective source of antioxidants.
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allfields	(DE-627)DOAJ040490491 (DE-599)DOAJ80e8427ace24479f8d30d414c5070a99 DE-627 ger DE-627 rakwb eng QH301-705.5 FENG HUANG verfasserin aut Antioxidant isolated from Schisandra propinqua (Wall.) Baill 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Schisandra propinqua (Wall.) Baill.(Schisandraceae) is widely used as a Chinese folk medicine. In this study, activity-guided fractionation of the ethanol extract from the stem of Schisandra propinqua led to the isolation of four extracts. Subsequently, a neolignan 4,4-di(4-hydroxy-3-methoxyphenly)-2,3-dimethylbutanol was isolated from the EtOAc part of the stem of Schisandra propinqua, the free radical scavenging activities of which were researched in vitro. The present work demonstrated that extracts and pure compound possessed scavenging activities to DPPH, superoxide anions and hydroxy radical, and could depress lipid peroxidation reaction induced by oxygen radical produced by the Fe2+/cysteine system in vitro. This suggests that the traditional application of Schisandra propinqua in China may be related to its antioxidant activities, and the EtOAc part of the stems of Schisandra propinqua can be utilized as an effective source of antioxidants. antioxidant free radical lipid peroxidation Schisandra propinqua Biology (General) LIJIA XU verfasserin aut SHI GANGGANG verfasserin aut In Biological Research BMC, 2018 42(2009), 3, Seite 351-356 (DE-627)329975374 (DE-600)2048380-6 07176287 nnns volume:42 year:2009 number:3 pages:351-356 https://doaj.org/article/80e8427ace24479f8d30d414c5070a99 kostenfrei http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602009000300009 kostenfrei https://doaj.org/toc/0716-9760 Journal toc kostenfrei https://doaj.org/toc/0717-6287 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 42 2009 3 351-356
spelling	(DE-627)DOAJ040490491 (DE-599)DOAJ80e8427ace24479f8d30d414c5070a99 DE-627 ger DE-627 rakwb eng QH301-705.5 FENG HUANG verfasserin aut Antioxidant isolated from Schisandra propinqua (Wall.) Baill 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Schisandra propinqua (Wall.) Baill.(Schisandraceae) is widely used as a Chinese folk medicine. In this study, activity-guided fractionation of the ethanol extract from the stem of Schisandra propinqua led to the isolation of four extracts. Subsequently, a neolignan 4,4-di(4-hydroxy-3-methoxyphenly)-2,3-dimethylbutanol was isolated from the EtOAc part of the stem of Schisandra propinqua, the free radical scavenging activities of which were researched in vitro. The present work demonstrated that extracts and pure compound possessed scavenging activities to DPPH, superoxide anions and hydroxy radical, and could depress lipid peroxidation reaction induced by oxygen radical produced by the Fe2+/cysteine system in vitro. This suggests that the traditional application of Schisandra propinqua in China may be related to its antioxidant activities, and the EtOAc part of the stems of Schisandra propinqua can be utilized as an effective source of antioxidants. antioxidant free radical lipid peroxidation Schisandra propinqua Biology (General) LIJIA XU verfasserin aut SHI GANGGANG verfasserin aut In Biological Research BMC, 2018 42(2009), 3, Seite 351-356 (DE-627)329975374 (DE-600)2048380-6 07176287 nnns volume:42 year:2009 number:3 pages:351-356 https://doaj.org/article/80e8427ace24479f8d30d414c5070a99 kostenfrei http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602009000300009 kostenfrei https://doaj.org/toc/0716-9760 Journal toc kostenfrei https://doaj.org/toc/0717-6287 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 42 2009 3 351-356
allfields_unstemmed	(DE-627)DOAJ040490491 (DE-599)DOAJ80e8427ace24479f8d30d414c5070a99 DE-627 ger DE-627 rakwb eng QH301-705.5 FENG HUANG verfasserin aut Antioxidant isolated from Schisandra propinqua (Wall.) Baill 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Schisandra propinqua (Wall.) Baill.(Schisandraceae) is widely used as a Chinese folk medicine. In this study, activity-guided fractionation of the ethanol extract from the stem of Schisandra propinqua led to the isolation of four extracts. Subsequently, a neolignan 4,4-di(4-hydroxy-3-methoxyphenly)-2,3-dimethylbutanol was isolated from the EtOAc part of the stem of Schisandra propinqua, the free radical scavenging activities of which were researched in vitro. The present work demonstrated that extracts and pure compound possessed scavenging activities to DPPH, superoxide anions and hydroxy radical, and could depress lipid peroxidation reaction induced by oxygen radical produced by the Fe2+/cysteine system in vitro. This suggests that the traditional application of Schisandra propinqua in China may be related to its antioxidant activities, and the EtOAc part of the stems of Schisandra propinqua can be utilized as an effective source of antioxidants. antioxidant free radical lipid peroxidation Schisandra propinqua Biology (General) LIJIA XU verfasserin aut SHI GANGGANG verfasserin aut In Biological Research BMC, 2018 42(2009), 3, Seite 351-356 (DE-627)329975374 (DE-600)2048380-6 07176287 nnns volume:42 year:2009 number:3 pages:351-356 https://doaj.org/article/80e8427ace24479f8d30d414c5070a99 kostenfrei http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602009000300009 kostenfrei https://doaj.org/toc/0716-9760 Journal toc kostenfrei https://doaj.org/toc/0717-6287 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 42 2009 3 351-356
allfieldsGer	(DE-627)DOAJ040490491 (DE-599)DOAJ80e8427ace24479f8d30d414c5070a99 DE-627 ger DE-627 rakwb eng QH301-705.5 FENG HUANG verfasserin aut Antioxidant isolated from Schisandra propinqua (Wall.) Baill 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Schisandra propinqua (Wall.) Baill.(Schisandraceae) is widely used as a Chinese folk medicine. In this study, activity-guided fractionation of the ethanol extract from the stem of Schisandra propinqua led to the isolation of four extracts. Subsequently, a neolignan 4,4-di(4-hydroxy-3-methoxyphenly)-2,3-dimethylbutanol was isolated from the EtOAc part of the stem of Schisandra propinqua, the free radical scavenging activities of which were researched in vitro. The present work demonstrated that extracts and pure compound possessed scavenging activities to DPPH, superoxide anions and hydroxy radical, and could depress lipid peroxidation reaction induced by oxygen radical produced by the Fe2+/cysteine system in vitro. This suggests that the traditional application of Schisandra propinqua in China may be related to its antioxidant activities, and the EtOAc part of the stems of Schisandra propinqua can be utilized as an effective source of antioxidants. antioxidant free radical lipid peroxidation Schisandra propinqua Biology (General) LIJIA XU verfasserin aut SHI GANGGANG verfasserin aut In Biological Research BMC, 2018 42(2009), 3, Seite 351-356 (DE-627)329975374 (DE-600)2048380-6 07176287 nnns volume:42 year:2009 number:3 pages:351-356 https://doaj.org/article/80e8427ace24479f8d30d414c5070a99 kostenfrei http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602009000300009 kostenfrei https://doaj.org/toc/0716-9760 Journal toc kostenfrei https://doaj.org/toc/0717-6287 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 42 2009 3 351-356
allfieldsSound	(DE-627)DOAJ040490491 (DE-599)DOAJ80e8427ace24479f8d30d414c5070a99 DE-627 ger DE-627 rakwb eng QH301-705.5 FENG HUANG verfasserin aut Antioxidant isolated from Schisandra propinqua (Wall.) Baill 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Schisandra propinqua (Wall.) Baill.(Schisandraceae) is widely used as a Chinese folk medicine. In this study, activity-guided fractionation of the ethanol extract from the stem of Schisandra propinqua led to the isolation of four extracts. Subsequently, a neolignan 4,4-di(4-hydroxy-3-methoxyphenly)-2,3-dimethylbutanol was isolated from the EtOAc part of the stem of Schisandra propinqua, the free radical scavenging activities of which were researched in vitro. The present work demonstrated that extracts and pure compound possessed scavenging activities to DPPH, superoxide anions and hydroxy radical, and could depress lipid peroxidation reaction induced by oxygen radical produced by the Fe2+/cysteine system in vitro. This suggests that the traditional application of Schisandra propinqua in China may be related to its antioxidant activities, and the EtOAc part of the stems of Schisandra propinqua can be utilized as an effective source of antioxidants. antioxidant free radical lipid peroxidation Schisandra propinqua Biology (General) LIJIA XU verfasserin aut SHI GANGGANG verfasserin aut In Biological Research BMC, 2018 42(2009), 3, Seite 351-356 (DE-627)329975374 (DE-600)2048380-6 07176287 nnns volume:42 year:2009 number:3 pages:351-356 https://doaj.org/article/80e8427ace24479f8d30d414c5070a99 kostenfrei http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602009000300009 kostenfrei https://doaj.org/toc/0716-9760 Journal toc kostenfrei https://doaj.org/toc/0717-6287 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 42 2009 3 351-356
language	English
source	In Biological Research 42(2009), 3, Seite 351-356 volume:42 year:2009 number:3 pages:351-356
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topic_facet	antioxidant free radical lipid peroxidation Schisandra propinqua Biology (General)
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authorswithroles_txt_mv	FENG HUANG @@aut@@ LIJIA XU @@aut@@ SHI GANGGANG @@aut@@
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author	FENG HUANG
spellingShingle	FENG HUANG misc QH301-705.5 misc antioxidant misc free radical misc lipid peroxidation misc Schisandra propinqua misc Biology (General) Antioxidant isolated from Schisandra propinqua (Wall.) Baill
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topic_title	QH301-705.5 Antioxidant isolated from Schisandra propinqua (Wall.) Baill antioxidant free radical lipid peroxidation Schisandra propinqua
topic	misc QH301-705.5 misc antioxidant misc free radical misc lipid peroxidation misc Schisandra propinqua misc Biology (General)
topic_unstemmed	misc QH301-705.5 misc antioxidant misc free radical misc lipid peroxidation misc Schisandra propinqua misc Biology (General)
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title	Antioxidant isolated from Schisandra propinqua (Wall.) Baill
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title_full	Antioxidant isolated from Schisandra propinqua (Wall.) Baill
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title_sort	antioxidant isolated from schisandra propinqua (wall.) baill
callnumber	QH301-705.5
title_auth	Antioxidant isolated from Schisandra propinqua (Wall.) Baill
abstract	Schisandra propinqua (Wall.) Baill.(Schisandraceae) is widely used as a Chinese folk medicine. In this study, activity-guided fractionation of the ethanol extract from the stem of Schisandra propinqua led to the isolation of four extracts. Subsequently, a neolignan 4,4-di(4-hydroxy-3-methoxyphenly)-2,3-dimethylbutanol was isolated from the EtOAc part of the stem of Schisandra propinqua, the free radical scavenging activities of which were researched in vitro. The present work demonstrated that extracts and pure compound possessed scavenging activities to DPPH, superoxide anions and hydroxy radical, and could depress lipid peroxidation reaction induced by oxygen radical produced by the Fe2+/cysteine system in vitro. This suggests that the traditional application of Schisandra propinqua in China may be related to its antioxidant activities, and the EtOAc part of the stems of Schisandra propinqua can be utilized as an effective source of antioxidants.
abstractGer	Schisandra propinqua (Wall.) Baill.(Schisandraceae) is widely used as a Chinese folk medicine. In this study, activity-guided fractionation of the ethanol extract from the stem of Schisandra propinqua led to the isolation of four extracts. Subsequently, a neolignan 4,4-di(4-hydroxy-3-methoxyphenly)-2,3-dimethylbutanol was isolated from the EtOAc part of the stem of Schisandra propinqua, the free radical scavenging activities of which were researched in vitro. The present work demonstrated that extracts and pure compound possessed scavenging activities to DPPH, superoxide anions and hydroxy radical, and could depress lipid peroxidation reaction induced by oxygen radical produced by the Fe2+/cysteine system in vitro. This suggests that the traditional application of Schisandra propinqua in China may be related to its antioxidant activities, and the EtOAc part of the stems of Schisandra propinqua can be utilized as an effective source of antioxidants.
abstract_unstemmed	Schisandra propinqua (Wall.) Baill.(Schisandraceae) is widely used as a Chinese folk medicine. In this study, activity-guided fractionation of the ethanol extract from the stem of Schisandra propinqua led to the isolation of four extracts. Subsequently, a neolignan 4,4-di(4-hydroxy-3-methoxyphenly)-2,3-dimethylbutanol was isolated from the EtOAc part of the stem of Schisandra propinqua, the free radical scavenging activities of which were researched in vitro. The present work demonstrated that extracts and pure compound possessed scavenging activities to DPPH, superoxide anions and hydroxy radical, and could depress lipid peroxidation reaction induced by oxygen radical produced by the Fe2+/cysteine system in vitro. This suggests that the traditional application of Schisandra propinqua in China may be related to its antioxidant activities, and the EtOAc part of the stems of Schisandra propinqua can be utilized as an effective source of antioxidants.
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title_short	Antioxidant isolated from Schisandra propinqua (Wall.) Baill
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