The 3’ End Prothrombin Gene Variants in Serbian Patients with Idiopathic Thrombophilia

Thrombophilia is a multifactorial disorder that arises from the interaction of acquired and genetic risk factors. Despite the significant efforts made to understand the etiology of this disease, there are still a certain number of patients suffering from idiopathic thrombophilia. The aim of this stu...
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Autor*in:	Aradjanski M. [verfasserIn] Djordjevic V. [verfasserIn] Pruner I. [verfasserIn] Tomic B. [verfasserIn] Gvozdenov M. [verfasserIn] Kovac M. [verfasserIn] Radojkovic D. [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2014

Schlagwörter:	3’ end prothrombin (fii) gene gene variants thrombophilia

Übergeordnetes Werk:	In: Balkan Journal of Medical Genetics - Sciendo, 2008, 17(2014), 2, Seite 43-48
Übergeordnetes Werk:	volume:17 ; year:2014 ; number:2 ; pages:43-48

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.2478/bjmg-2014-0073

Katalog-ID:	DOAJ041109856

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spelling	10.2478/bjmg-2014-0073 doi (DE-627)DOAJ041109856 (DE-599)DOAJe1c63f7347324e0290c861ed131e9585 DE-627 ger DE-627 rakwb eng QH426-470 Aradjanski M. verfasserin aut The 3’ End Prothrombin Gene Variants in Serbian Patients with Idiopathic Thrombophilia 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Thrombophilia is a multifactorial disorder that arises from the interaction of acquired and genetic risk factors. Despite the significant efforts made to understand the etiology of this disease, there are still a certain number of patients suffering from idiopathic thrombophilia. The aim of this study was to screen the 3’ end of the prothrombin (FII) gene, which is susceptible to gain-of-function mutations due to its non canonical architecture, in patients with idiopathic thrombophilia and to determine its eventual role in the pathogenesis of thrombophilia. 3’ end prothrombin (fii) gene gene variants thrombophilia Genetics Djordjevic V. verfasserin aut Pruner I. verfasserin aut Tomic B. verfasserin aut Gvozdenov M. verfasserin aut Kovac M. verfasserin aut Radojkovic D. verfasserin aut In Balkan Journal of Medical Genetics Sciendo, 2008 17(2014), 2, Seite 43-48 (DE-627)556296079 (DE-600)2402171-4 13110160 nnns volume:17 year:2014 number:2 pages:43-48 https://doi.org/10.2478/bjmg-2014-0073 kostenfrei https://doaj.org/article/e1c63f7347324e0290c861ed131e9585 kostenfrei https://doi.org/10.2478/bjmg-2014-0073 kostenfrei https://doaj.org/toc/1311-0160 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 17 2014 2 43-48
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allfieldsGer	10.2478/bjmg-2014-0073 doi (DE-627)DOAJ041109856 (DE-599)DOAJe1c63f7347324e0290c861ed131e9585 DE-627 ger DE-627 rakwb eng QH426-470 Aradjanski M. verfasserin aut The 3’ End Prothrombin Gene Variants in Serbian Patients with Idiopathic Thrombophilia 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Thrombophilia is a multifactorial disorder that arises from the interaction of acquired and genetic risk factors. Despite the significant efforts made to understand the etiology of this disease, there are still a certain number of patients suffering from idiopathic thrombophilia. The aim of this study was to screen the 3’ end of the prothrombin (FII) gene, which is susceptible to gain-of-function mutations due to its non canonical architecture, in patients with idiopathic thrombophilia and to determine its eventual role in the pathogenesis of thrombophilia. 3’ end prothrombin (fii) gene gene variants thrombophilia Genetics Djordjevic V. verfasserin aut Pruner I. verfasserin aut Tomic B. verfasserin aut Gvozdenov M. verfasserin aut Kovac M. verfasserin aut Radojkovic D. verfasserin aut In Balkan Journal of Medical Genetics Sciendo, 2008 17(2014), 2, Seite 43-48 (DE-627)556296079 (DE-600)2402171-4 13110160 nnns volume:17 year:2014 number:2 pages:43-48 https://doi.org/10.2478/bjmg-2014-0073 kostenfrei https://doaj.org/article/e1c63f7347324e0290c861ed131e9585 kostenfrei https://doi.org/10.2478/bjmg-2014-0073 kostenfrei https://doaj.org/toc/1311-0160 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 17 2014 2 43-48
allfieldsSound	10.2478/bjmg-2014-0073 doi (DE-627)DOAJ041109856 (DE-599)DOAJe1c63f7347324e0290c861ed131e9585 DE-627 ger DE-627 rakwb eng QH426-470 Aradjanski M. verfasserin aut The 3’ End Prothrombin Gene Variants in Serbian Patients with Idiopathic Thrombophilia 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Thrombophilia is a multifactorial disorder that arises from the interaction of acquired and genetic risk factors. Despite the significant efforts made to understand the etiology of this disease, there are still a certain number of patients suffering from idiopathic thrombophilia. The aim of this study was to screen the 3’ end of the prothrombin (FII) gene, which is susceptible to gain-of-function mutations due to its non canonical architecture, in patients with idiopathic thrombophilia and to determine its eventual role in the pathogenesis of thrombophilia. 3’ end prothrombin (fii) gene gene variants thrombophilia Genetics Djordjevic V. verfasserin aut Pruner I. verfasserin aut Tomic B. verfasserin aut Gvozdenov M. verfasserin aut Kovac M. verfasserin aut Radojkovic D. verfasserin aut In Balkan Journal of Medical Genetics Sciendo, 2008 17(2014), 2, Seite 43-48 (DE-627)556296079 (DE-600)2402171-4 13110160 nnns volume:17 year:2014 number:2 pages:43-48 https://doi.org/10.2478/bjmg-2014-0073 kostenfrei https://doaj.org/article/e1c63f7347324e0290c861ed131e9585 kostenfrei https://doi.org/10.2478/bjmg-2014-0073 kostenfrei https://doaj.org/toc/1311-0160 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 17 2014 2 43-48
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author	Aradjanski M.
spellingShingle	Aradjanski M. misc QH426-470 misc 3’ end prothrombin (fii) gene misc gene variants misc thrombophilia misc Genetics The 3’ End Prothrombin Gene Variants in Serbian Patients with Idiopathic Thrombophilia
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topic_title	QH426-470 The 3’ End Prothrombin Gene Variants in Serbian Patients with Idiopathic Thrombophilia 3’ end prothrombin (fii) gene gene variants thrombophilia
topic	misc QH426-470 misc 3’ end prothrombin (fii) gene misc gene variants misc thrombophilia misc Genetics
topic_unstemmed	misc QH426-470 misc 3’ end prothrombin (fii) gene misc gene variants misc thrombophilia misc Genetics
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title	The 3’ End Prothrombin Gene Variants in Serbian Patients with Idiopathic Thrombophilia
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title_sort	3’ end prothrombin gene variants in serbian patients with idiopathic thrombophilia
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title_auth	The 3’ End Prothrombin Gene Variants in Serbian Patients with Idiopathic Thrombophilia
abstract	Thrombophilia is a multifactorial disorder that arises from the interaction of acquired and genetic risk factors. Despite the significant efforts made to understand the etiology of this disease, there are still a certain number of patients suffering from idiopathic thrombophilia. The aim of this study was to screen the 3’ end of the prothrombin (FII) gene, which is susceptible to gain-of-function mutations due to its non canonical architecture, in patients with idiopathic thrombophilia and to determine its eventual role in the pathogenesis of thrombophilia.
abstractGer	Thrombophilia is a multifactorial disorder that arises from the interaction of acquired and genetic risk factors. Despite the significant efforts made to understand the etiology of this disease, there are still a certain number of patients suffering from idiopathic thrombophilia. The aim of this study was to screen the 3’ end of the prothrombin (FII) gene, which is susceptible to gain-of-function mutations due to its non canonical architecture, in patients with idiopathic thrombophilia and to determine its eventual role in the pathogenesis of thrombophilia.
abstract_unstemmed	Thrombophilia is a multifactorial disorder that arises from the interaction of acquired and genetic risk factors. Despite the significant efforts made to understand the etiology of this disease, there are still a certain number of patients suffering from idiopathic thrombophilia. The aim of this study was to screen the 3’ end of the prothrombin (FII) gene, which is susceptible to gain-of-function mutations due to its non canonical architecture, in patients with idiopathic thrombophilia and to determine its eventual role in the pathogenesis of thrombophilia.
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title_short	The 3’ End Prothrombin Gene Variants in Serbian Patients with Idiopathic Thrombophilia
url	https://doi.org/10.2478/bjmg-2014-0073 https://doaj.org/article/e1c63f7347324e0290c861ed131e9585 https://doaj.org/toc/1311-0160
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