Roles of neural stem cells in the repair of peripheral nerve injury

Currently, researchers are using neural stem cell transplantation to promote regeneration after peripheral nerve injury, as neural stem cells play an important role in peripheral nerve injury repair. This article reviews recent research progress of the role of neural stem cells in the repair of peri...
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Gespeichert in:

Autor*in:	Chong Wang [verfasserIn] Chang-feng Lu [verfasserIn] Jiang Peng [verfasserIn] Cheng-dong Hu [verfasserIn] Yu Wang [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2017

Schlagwörter:	nerve regeneration; neural stem cells; peripheral nerve; regeneration; Schwann-like cells; neurons; neurotrophic factors; neuroprotection; axons; angiogenesis; immune regulation; neural regeneration

Übergeordnetes Werk:	In: Neural Regeneration Research - Wolters Kluwer Medknow Publications, 2014, 12(2017), 12, Seite 2106-2112
Übergeordnetes Werk:	volume:12 ; year:2017 ; number:12 ; pages:2106-2112

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.4103/1673-5374.221171

Katalog-ID:	DOAJ041439112

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topic_facet	nerve regeneration; neural stem cells; peripheral nerve; regeneration; Schwann-like cells; neurons; neurotrophic factors; neuroprotection; axons; angiogenesis; immune regulation; neural regeneration Neurology. Diseases of the nervous system
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callnumber-first	R - Medicine
author	Chong Wang
spellingShingle	Chong Wang misc RC346-429 misc nerve regeneration; neural stem cells; peripheral nerve; regeneration; Schwann-like cells; neurons; neurotrophic factors; neuroprotection; axons; angiogenesis; immune regulation; neural regeneration misc Neurology. Diseases of the nervous system Roles of neural stem cells in the repair of peripheral nerve injury
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topic_title	RC346-429 Roles of neural stem cells in the repair of peripheral nerve injury nerve regeneration; neural stem cells; peripheral nerve; regeneration; Schwann-like cells; neurons; neurotrophic factors; neuroprotection; axons; angiogenesis; immune regulation; neural regeneration
topic	misc RC346-429 misc nerve regeneration; neural stem cells; peripheral nerve; regeneration; Schwann-like cells; neurons; neurotrophic factors; neuroprotection; axons; angiogenesis; immune regulation; neural regeneration misc Neurology. Diseases of the nervous system
topic_unstemmed	misc RC346-429 misc nerve regeneration; neural stem cells; peripheral nerve; regeneration; Schwann-like cells; neurons; neurotrophic factors; neuroprotection; axons; angiogenesis; immune regulation; neural regeneration misc Neurology. Diseases of the nervous system
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title	Roles of neural stem cells in the repair of peripheral nerve injury
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title_auth	Roles of neural stem cells in the repair of peripheral nerve injury
abstract	Currently, researchers are using neural stem cell transplantation to promote regeneration after peripheral nerve injury, as neural stem cells play an important role in peripheral nerve injury repair. This article reviews recent research progress of the role of neural stem cells in the repair of peripheral nerve injury. Neural stem cells can not only differentiate into neurons, astrocytes and oligodendrocytes, but can also differentiate into Schwann-like cells, which promote neurite outgrowth around the injury. Transplanted neural stem cells can differentiate into motor neurons that innervate muscles and promote the recovery of neurological function. To promote the repair of peripheral nerve injury, neural stem cells secrete various neurotrophic factors, including brain-derived neurotrophic factor, fibroblast growth factor, nerve growth factor, insulin-like growth factor and hepatocyte growth factor. In addition, neural stem cells also promote regeneration of the axonal myelin sheath, angiogenesis, and immune regulation. It can be concluded that neural stem cells promote the repair of peripheral nerve injury through a variety of ways.
abstractGer	Currently, researchers are using neural stem cell transplantation to promote regeneration after peripheral nerve injury, as neural stem cells play an important role in peripheral nerve injury repair. This article reviews recent research progress of the role of neural stem cells in the repair of peripheral nerve injury. Neural stem cells can not only differentiate into neurons, astrocytes and oligodendrocytes, but can also differentiate into Schwann-like cells, which promote neurite outgrowth around the injury. Transplanted neural stem cells can differentiate into motor neurons that innervate muscles and promote the recovery of neurological function. To promote the repair of peripheral nerve injury, neural stem cells secrete various neurotrophic factors, including brain-derived neurotrophic factor, fibroblast growth factor, nerve growth factor, insulin-like growth factor and hepatocyte growth factor. In addition, neural stem cells also promote regeneration of the axonal myelin sheath, angiogenesis, and immune regulation. It can be concluded that neural stem cells promote the repair of peripheral nerve injury through a variety of ways.
abstract_unstemmed	Currently, researchers are using neural stem cell transplantation to promote regeneration after peripheral nerve injury, as neural stem cells play an important role in peripheral nerve injury repair. This article reviews recent research progress of the role of neural stem cells in the repair of peripheral nerve injury. Neural stem cells can not only differentiate into neurons, astrocytes and oligodendrocytes, but can also differentiate into Schwann-like cells, which promote neurite outgrowth around the injury. Transplanted neural stem cells can differentiate into motor neurons that innervate muscles and promote the recovery of neurological function. To promote the repair of peripheral nerve injury, neural stem cells secrete various neurotrophic factors, including brain-derived neurotrophic factor, fibroblast growth factor, nerve growth factor, insulin-like growth factor and hepatocyte growth factor. In addition, neural stem cells also promote regeneration of the axonal myelin sheath, angiogenesis, and immune regulation. It can be concluded that neural stem cells promote the repair of peripheral nerve injury through a variety of ways.
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title_short	Roles of neural stem cells in the repair of peripheral nerve injury
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Roles of neural stem cells in the repair of peripheral nerve injury

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