The correction of impaired bone tissue metabolism – is a component of complex therapy for chronic post-traumatic osteomyelitis of long bones
Background. The genesis of bone and joint infection can not be described simply as a local destruction of bone tissue. The influence of the pathogen on bone remodeling reduces the effectiveness of conventional therapeutic measures. In this research, the possibility of supplementing the standard trea...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
A.V. Tsiskarashvili [verfasserIn] A.Yu. Taraskin [verfasserIn] D.S. Gorbatyuk [verfasserIn] S.S. Rodionova [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch ; Russisch |
| Erschienen: |
2022 |
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| Schlagwörter: |
metabolic disorders of bone tissue |
|---|
| Übergeordnetes Werk: |
In: Известия высших учебных заведений. Поволжский регион: Медицинские науки - Penza State University Publishing House, 2020, (2022), 1 |
|---|---|
| Übergeordnetes Werk: |
year:2022 ; number:1 |
| Links: |
|---|
| DOI / URN: |
10.21685/2072-3032-2022-1-2 |
|---|
| Katalog-ID: |
DOAJ041632788 |
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| 520 | |a Background. The genesis of bone and joint infection can not be described simply as a local destruction of bone tissue. The influence of the pathogen on bone remodeling reduces the effectiveness of conventional therapeutic measures. In this research, the possibility of supplementing the standard treatment regimen is analyzed, which includes surgery and antibacterial drugs, with therapy aimed at correction of metabolic disorders in the bone tissue that occur with the infectious process as a background. The purpose of the study is to demonstrate the effectiveness of the use of alfacalcidol, ossein-hydroxyapatite complex and bisphosphonate in combination with the generally accepted protocol for the treatment of pseudarthrosis of long bones with the background of chronic osteomyelitis. Materials and methods. A clinical example is presented, with the consistent use of standard therapy, and subsequent, associated with an unsatisfactory result, the appointment of an examination for the presence of balance disorders of bone remodeling, as well as further therapeutic correction of the identified disorders in combination with surgical treatment and antibacterial therapy. Results. This observation confirms the presence of metabolic disorders in the bone tissue in a patient with chronic osteomyelitis (consistent with previous scientific works). Normalization of bone remodeling indicators against the background of the therapy performed, as we believe, became the basis for a positive outcome of treatment. Conclusion. The data obtained indicate that the therapy aimed at correcting metabolic disorders, as an addition to generally accepted methods of treatment, contributes to achieving a favorable result. | ||
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The correction of impaired bone tissue metabolism – is a component of complex therapy for chronic post-traumatic osteomyelitis of long bones |
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A.V. Tsiskarashvili |
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Известия высших учебных заведений. Поволжский регион: Медицинские науки |
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Известия высших учебных заведений. Поволжский регион: Медицинские науки |
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A.V. Tsiskarashvili A.Yu. Taraskin D.S. Gorbatyuk S.S. Rodionova |
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A.V. Tsiskarashvili |
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10.21685/2072-3032-2022-1-2 |
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verfasserin |
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correction of impaired bone tissue metabolism – is a component of complex therapy for chronic post-traumatic osteomyelitis of long bones |
| title_auth |
The correction of impaired bone tissue metabolism – is a component of complex therapy for chronic post-traumatic osteomyelitis of long bones |
| abstract |
Background. The genesis of bone and joint infection can not be described simply as a local destruction of bone tissue. The influence of the pathogen on bone remodeling reduces the effectiveness of conventional therapeutic measures. In this research, the possibility of supplementing the standard treatment regimen is analyzed, which includes surgery and antibacterial drugs, with therapy aimed at correction of metabolic disorders in the bone tissue that occur with the infectious process as a background. The purpose of the study is to demonstrate the effectiveness of the use of alfacalcidol, ossein-hydroxyapatite complex and bisphosphonate in combination with the generally accepted protocol for the treatment of pseudarthrosis of long bones with the background of chronic osteomyelitis. Materials and methods. A clinical example is presented, with the consistent use of standard therapy, and subsequent, associated with an unsatisfactory result, the appointment of an examination for the presence of balance disorders of bone remodeling, as well as further therapeutic correction of the identified disorders in combination with surgical treatment and antibacterial therapy. Results. This observation confirms the presence of metabolic disorders in the bone tissue in a patient with chronic osteomyelitis (consistent with previous scientific works). Normalization of bone remodeling indicators against the background of the therapy performed, as we believe, became the basis for a positive outcome of treatment. Conclusion. The data obtained indicate that the therapy aimed at correcting metabolic disorders, as an addition to generally accepted methods of treatment, contributes to achieving a favorable result. |
| abstractGer |
Background. The genesis of bone and joint infection can not be described simply as a local destruction of bone tissue. The influence of the pathogen on bone remodeling reduces the effectiveness of conventional therapeutic measures. In this research, the possibility of supplementing the standard treatment regimen is analyzed, which includes surgery and antibacterial drugs, with therapy aimed at correction of metabolic disorders in the bone tissue that occur with the infectious process as a background. The purpose of the study is to demonstrate the effectiveness of the use of alfacalcidol, ossein-hydroxyapatite complex and bisphosphonate in combination with the generally accepted protocol for the treatment of pseudarthrosis of long bones with the background of chronic osteomyelitis. Materials and methods. A clinical example is presented, with the consistent use of standard therapy, and subsequent, associated with an unsatisfactory result, the appointment of an examination for the presence of balance disorders of bone remodeling, as well as further therapeutic correction of the identified disorders in combination with surgical treatment and antibacterial therapy. Results. This observation confirms the presence of metabolic disorders in the bone tissue in a patient with chronic osteomyelitis (consistent with previous scientific works). Normalization of bone remodeling indicators against the background of the therapy performed, as we believe, became the basis for a positive outcome of treatment. Conclusion. The data obtained indicate that the therapy aimed at correcting metabolic disorders, as an addition to generally accepted methods of treatment, contributes to achieving a favorable result. |
| abstract_unstemmed |
Background. The genesis of bone and joint infection can not be described simply as a local destruction of bone tissue. The influence of the pathogen on bone remodeling reduces the effectiveness of conventional therapeutic measures. In this research, the possibility of supplementing the standard treatment regimen is analyzed, which includes surgery and antibacterial drugs, with therapy aimed at correction of metabolic disorders in the bone tissue that occur with the infectious process as a background. The purpose of the study is to demonstrate the effectiveness of the use of alfacalcidol, ossein-hydroxyapatite complex and bisphosphonate in combination with the generally accepted protocol for the treatment of pseudarthrosis of long bones with the background of chronic osteomyelitis. Materials and methods. A clinical example is presented, with the consistent use of standard therapy, and subsequent, associated with an unsatisfactory result, the appointment of an examination for the presence of balance disorders of bone remodeling, as well as further therapeutic correction of the identified disorders in combination with surgical treatment and antibacterial therapy. Results. This observation confirms the presence of metabolic disorders in the bone tissue in a patient with chronic osteomyelitis (consistent with previous scientific works). Normalization of bone remodeling indicators against the background of the therapy performed, as we believe, became the basis for a positive outcome of treatment. Conclusion. The data obtained indicate that the therapy aimed at correcting metabolic disorders, as an addition to generally accepted methods of treatment, contributes to achieving a favorable result. |
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The correction of impaired bone tissue metabolism – is a component of complex therapy for chronic post-traumatic osteomyelitis of long bones |
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https://doi.org/10.21685/2072-3032-2022-1-2 https://doaj.org/article/afda2c7f123f41ca99829e53b72748f6 https://doaj.org/toc/2072-3032 |
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