Prevalence of Arterial Hypertension and Characteristics of Nocturnal Blood Pressure Profile of Asthma Patients According to Therapy and Severity of the Disease: The BADA Study

Background: several studies report an increased risk for asthmatic subjects to develop arterial hypertension and the relationship between these two diseases, frequently co-existing, still has some unclear aspects. Methods: The BADA (blood pressure levels, clinical features and markers of subclinical...
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Autor*in:	Domenico Di Raimondo [verfasserIn] Gaia Musiari [verfasserIn] Alida Benfante [verfasserIn] Salvatore Battaglia [verfasserIn] Giuliana Rizzo [verfasserIn] Antonino Tuttolomondo [verfasserIn] Nicola Scichilone [verfasserIn] Antonio Pinto [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2020

Schlagwörter:	asthma cardiovascular risk essential hypertension inhaled corticosteroid therapy nocturnal dipping of blood pressure

Übergeordnetes Werk:	In: International Journal of Environmental Research and Public Health - MDPI AG, 2005, 17(2020), 6925, p 6925
Übergeordnetes Werk:	volume:17 ; year:2020 ; number:6925, p 6925

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.3390/ijerph17186925

Katalog-ID:	DOAJ041844300

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allfields	10.3390/ijerph17186925 doi (DE-627)DOAJ041844300 (DE-599)DOAJbbd46d09ecaa45d2bddf6a8af4080a67 DE-627 ger DE-627 rakwb eng Domenico Di Raimondo verfasserin aut Prevalence of Arterial Hypertension and Characteristics of Nocturnal Blood Pressure Profile of Asthma Patients According to Therapy and Severity of the Disease: The BADA Study 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: several studies report an increased risk for asthmatic subjects to develop arterial hypertension and the relationship between these two diseases, frequently co-existing, still has some unclear aspects. Methods: The BADA (blood pressure levels, clinical features and markers of subclinical cardiovascular damage of asthma patients) study is aimed to evaluate the prevalence of the cardiovascular comorbidities of asthma and their impact on the clinical outcome. The main exclusion criteria were the presence of other respiratory diseases, current smoking, any contraindication to ambulatory blood pressure monitoring (ABPM). Results: The overall percentage of asthmatics having also hypertension was 75% (30 patients) vs 45% (18 patients) of the control group (<i<p</i<: 0.012). Reduced level of FEV<sub<1 </sub<(but not inhaled steroid therapy) was associated to newly-diagnosed hypertension (<i<p</i<: 0.0002), higher day SBP levels (<i<p</i<: 0.003), higher day DBP levels (<i<p</i<: 0.03), higher 24 h-SBP levels (<i<p</i<: 0.005) and higher 24h-DBP levels (<i<p</i<: 0.03). The regression analysis performed taking into account sex, age, diabetes, fasting glucose, and body mass index confirms the independent role played by asthma: odds ratio (OR): 3.66 (CI: 1.29–11.1). Conclusions: hypertension is highly prevalent in asthma; the use of ABPM has allowed the detection of a considerable number of unrecognized hypertensives. asthma cardiovascular risk essential hypertension inhaled corticosteroid therapy nocturnal dipping of blood pressure Medicine R Gaia Musiari verfasserin aut Alida Benfante verfasserin aut Salvatore Battaglia verfasserin aut Giuliana Rizzo verfasserin aut Antonino Tuttolomondo verfasserin aut Nicola Scichilone verfasserin aut Antonio Pinto verfasserin aut In International Journal of Environmental Research and Public Health MDPI AG, 2005 17(2020), 6925, p 6925 (DE-627)477992463 (DE-600)2175195-X 16604601 nnns volume:17 year:2020 number:6925, p 6925 https://doi.org/10.3390/ijerph17186925 kostenfrei https://doaj.org/article/bbd46d09ecaa45d2bddf6a8af4080a67 kostenfrei https://www.mdpi.com/1660-4601/17/18/6925 kostenfrei https://doaj.org/toc/1661-7827 Journal toc kostenfrei https://doaj.org/toc/1660-4601 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2153 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 17 2020 6925, p 6925
spelling	10.3390/ijerph17186925 doi (DE-627)DOAJ041844300 (DE-599)DOAJbbd46d09ecaa45d2bddf6a8af4080a67 DE-627 ger DE-627 rakwb eng Domenico Di Raimondo verfasserin aut Prevalence of Arterial Hypertension and Characteristics of Nocturnal Blood Pressure Profile of Asthma Patients According to Therapy and Severity of the Disease: The BADA Study 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: several studies report an increased risk for asthmatic subjects to develop arterial hypertension and the relationship between these two diseases, frequently co-existing, still has some unclear aspects. Methods: The BADA (blood pressure levels, clinical features and markers of subclinical cardiovascular damage of asthma patients) study is aimed to evaluate the prevalence of the cardiovascular comorbidities of asthma and their impact on the clinical outcome. The main exclusion criteria were the presence of other respiratory diseases, current smoking, any contraindication to ambulatory blood pressure monitoring (ABPM). Results: The overall percentage of asthmatics having also hypertension was 75% (30 patients) vs 45% (18 patients) of the control group (<i<p</i<: 0.012). Reduced level of FEV<sub<1 </sub<(but not inhaled steroid therapy) was associated to newly-diagnosed hypertension (<i<p</i<: 0.0002), higher day SBP levels (<i<p</i<: 0.003), higher day DBP levels (<i<p</i<: 0.03), higher 24 h-SBP levels (<i<p</i<: 0.005) and higher 24h-DBP levels (<i<p</i<: 0.03). The regression analysis performed taking into account sex, age, diabetes, fasting glucose, and body mass index confirms the independent role played by asthma: odds ratio (OR): 3.66 (CI: 1.29–11.1). Conclusions: hypertension is highly prevalent in asthma; the use of ABPM has allowed the detection of a considerable number of unrecognized hypertensives. asthma cardiovascular risk essential hypertension inhaled corticosteroid therapy nocturnal dipping of blood pressure Medicine R Gaia Musiari verfasserin aut Alida Benfante verfasserin aut Salvatore Battaglia verfasserin aut Giuliana Rizzo verfasserin aut Antonino Tuttolomondo verfasserin aut Nicola Scichilone verfasserin aut Antonio Pinto verfasserin aut In International Journal of Environmental Research and Public Health MDPI AG, 2005 17(2020), 6925, p 6925 (DE-627)477992463 (DE-600)2175195-X 16604601 nnns volume:17 year:2020 number:6925, p 6925 https://doi.org/10.3390/ijerph17186925 kostenfrei https://doaj.org/article/bbd46d09ecaa45d2bddf6a8af4080a67 kostenfrei https://www.mdpi.com/1660-4601/17/18/6925 kostenfrei https://doaj.org/toc/1661-7827 Journal toc kostenfrei https://doaj.org/toc/1660-4601 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2153 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 17 2020 6925, p 6925
allfields_unstemmed	10.3390/ijerph17186925 doi (DE-627)DOAJ041844300 (DE-599)DOAJbbd46d09ecaa45d2bddf6a8af4080a67 DE-627 ger DE-627 rakwb eng Domenico Di Raimondo verfasserin aut Prevalence of Arterial Hypertension and Characteristics of Nocturnal Blood Pressure Profile of Asthma Patients According to Therapy and Severity of the Disease: The BADA Study 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: several studies report an increased risk for asthmatic subjects to develop arterial hypertension and the relationship between these two diseases, frequently co-existing, still has some unclear aspects. Methods: The BADA (blood pressure levels, clinical features and markers of subclinical cardiovascular damage of asthma patients) study is aimed to evaluate the prevalence of the cardiovascular comorbidities of asthma and their impact on the clinical outcome. The main exclusion criteria were the presence of other respiratory diseases, current smoking, any contraindication to ambulatory blood pressure monitoring (ABPM). Results: The overall percentage of asthmatics having also hypertension was 75% (30 patients) vs 45% (18 patients) of the control group (<i<p</i<: 0.012). Reduced level of FEV<sub<1 </sub<(but not inhaled steroid therapy) was associated to newly-diagnosed hypertension (<i<p</i<: 0.0002), higher day SBP levels (<i<p</i<: 0.003), higher day DBP levels (<i<p</i<: 0.03), higher 24 h-SBP levels (<i<p</i<: 0.005) and higher 24h-DBP levels (<i<p</i<: 0.03). The regression analysis performed taking into account sex, age, diabetes, fasting glucose, and body mass index confirms the independent role played by asthma: odds ratio (OR): 3.66 (CI: 1.29–11.1). Conclusions: hypertension is highly prevalent in asthma; the use of ABPM has allowed the detection of a considerable number of unrecognized hypertensives. asthma cardiovascular risk essential hypertension inhaled corticosteroid therapy nocturnal dipping of blood pressure Medicine R Gaia Musiari verfasserin aut Alida Benfante verfasserin aut Salvatore Battaglia verfasserin aut Giuliana Rizzo verfasserin aut Antonino Tuttolomondo verfasserin aut Nicola Scichilone verfasserin aut Antonio Pinto verfasserin aut In International Journal of Environmental Research and Public Health MDPI AG, 2005 17(2020), 6925, p 6925 (DE-627)477992463 (DE-600)2175195-X 16604601 nnns volume:17 year:2020 number:6925, p 6925 https://doi.org/10.3390/ijerph17186925 kostenfrei https://doaj.org/article/bbd46d09ecaa45d2bddf6a8af4080a67 kostenfrei https://www.mdpi.com/1660-4601/17/18/6925 kostenfrei https://doaj.org/toc/1661-7827 Journal toc kostenfrei https://doaj.org/toc/1660-4601 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2153 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 17 2020 6925, p 6925
allfieldsGer	10.3390/ijerph17186925 doi (DE-627)DOAJ041844300 (DE-599)DOAJbbd46d09ecaa45d2bddf6a8af4080a67 DE-627 ger DE-627 rakwb eng Domenico Di Raimondo verfasserin aut Prevalence of Arterial Hypertension and Characteristics of Nocturnal Blood Pressure Profile of Asthma Patients According to Therapy and Severity of the Disease: The BADA Study 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: several studies report an increased risk for asthmatic subjects to develop arterial hypertension and the relationship between these two diseases, frequently co-existing, still has some unclear aspects. Methods: The BADA (blood pressure levels, clinical features and markers of subclinical cardiovascular damage of asthma patients) study is aimed to evaluate the prevalence of the cardiovascular comorbidities of asthma and their impact on the clinical outcome. The main exclusion criteria were the presence of other respiratory diseases, current smoking, any contraindication to ambulatory blood pressure monitoring (ABPM). Results: The overall percentage of asthmatics having also hypertension was 75% (30 patients) vs 45% (18 patients) of the control group (<i<p</i<: 0.012). Reduced level of FEV<sub<1 </sub<(but not inhaled steroid therapy) was associated to newly-diagnosed hypertension (<i<p</i<: 0.0002), higher day SBP levels (<i<p</i<: 0.003), higher day DBP levels (<i<p</i<: 0.03), higher 24 h-SBP levels (<i<p</i<: 0.005) and higher 24h-DBP levels (<i<p</i<: 0.03). The regression analysis performed taking into account sex, age, diabetes, fasting glucose, and body mass index confirms the independent role played by asthma: odds ratio (OR): 3.66 (CI: 1.29–11.1). Conclusions: hypertension is highly prevalent in asthma; the use of ABPM has allowed the detection of a considerable number of unrecognized hypertensives. asthma cardiovascular risk essential hypertension inhaled corticosteroid therapy nocturnal dipping of blood pressure Medicine R Gaia Musiari verfasserin aut Alida Benfante verfasserin aut Salvatore Battaglia verfasserin aut Giuliana Rizzo verfasserin aut Antonino Tuttolomondo verfasserin aut Nicola Scichilone verfasserin aut Antonio Pinto verfasserin aut In International Journal of Environmental Research and Public Health MDPI AG, 2005 17(2020), 6925, p 6925 (DE-627)477992463 (DE-600)2175195-X 16604601 nnns volume:17 year:2020 number:6925, p 6925 https://doi.org/10.3390/ijerph17186925 kostenfrei https://doaj.org/article/bbd46d09ecaa45d2bddf6a8af4080a67 kostenfrei https://www.mdpi.com/1660-4601/17/18/6925 kostenfrei https://doaj.org/toc/1661-7827 Journal toc kostenfrei https://doaj.org/toc/1660-4601 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2153 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 17 2020 6925, p 6925
allfieldsSound	10.3390/ijerph17186925 doi (DE-627)DOAJ041844300 (DE-599)DOAJbbd46d09ecaa45d2bddf6a8af4080a67 DE-627 ger DE-627 rakwb eng Domenico Di Raimondo verfasserin aut Prevalence of Arterial Hypertension and Characteristics of Nocturnal Blood Pressure Profile of Asthma Patients According to Therapy and Severity of the Disease: The BADA Study 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: several studies report an increased risk for asthmatic subjects to develop arterial hypertension and the relationship between these two diseases, frequently co-existing, still has some unclear aspects. Methods: The BADA (blood pressure levels, clinical features and markers of subclinical cardiovascular damage of asthma patients) study is aimed to evaluate the prevalence of the cardiovascular comorbidities of asthma and their impact on the clinical outcome. The main exclusion criteria were the presence of other respiratory diseases, current smoking, any contraindication to ambulatory blood pressure monitoring (ABPM). Results: The overall percentage of asthmatics having also hypertension was 75% (30 patients) vs 45% (18 patients) of the control group (<i<p</i<: 0.012). Reduced level of FEV<sub<1 </sub<(but not inhaled steroid therapy) was associated to newly-diagnosed hypertension (<i<p</i<: 0.0002), higher day SBP levels (<i<p</i<: 0.003), higher day DBP levels (<i<p</i<: 0.03), higher 24 h-SBP levels (<i<p</i<: 0.005) and higher 24h-DBP levels (<i<p</i<: 0.03). The regression analysis performed taking into account sex, age, diabetes, fasting glucose, and body mass index confirms the independent role played by asthma: odds ratio (OR): 3.66 (CI: 1.29–11.1). Conclusions: hypertension is highly prevalent in asthma; the use of ABPM has allowed the detection of a considerable number of unrecognized hypertensives. asthma cardiovascular risk essential hypertension inhaled corticosteroid therapy nocturnal dipping of blood pressure Medicine R Gaia Musiari verfasserin aut Alida Benfante verfasserin aut Salvatore Battaglia verfasserin aut Giuliana Rizzo verfasserin aut Antonino Tuttolomondo verfasserin aut Nicola Scichilone verfasserin aut Antonio Pinto verfasserin aut In International Journal of Environmental Research and Public Health MDPI AG, 2005 17(2020), 6925, p 6925 (DE-627)477992463 (DE-600)2175195-X 16604601 nnns volume:17 year:2020 number:6925, p 6925 https://doi.org/10.3390/ijerph17186925 kostenfrei https://doaj.org/article/bbd46d09ecaa45d2bddf6a8af4080a67 kostenfrei https://www.mdpi.com/1660-4601/17/18/6925 kostenfrei https://doaj.org/toc/1661-7827 Journal toc kostenfrei https://doaj.org/toc/1660-4601 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2153 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 17 2020 6925, p 6925
language	English
source	In International Journal of Environmental Research and Public Health 17(2020), 6925, p 6925 volume:17 year:2020 number:6925, p 6925
sourceStr	In International Journal of Environmental Research and Public Health 17(2020), 6925, p 6925 volume:17 year:2020 number:6925, p 6925
format_phy_str_mv	Article
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author	Domenico Di Raimondo
spellingShingle	Domenico Di Raimondo misc asthma misc cardiovascular risk misc essential hypertension misc inhaled corticosteroid therapy misc nocturnal dipping of blood pressure misc Medicine misc R Prevalence of Arterial Hypertension and Characteristics of Nocturnal Blood Pressure Profile of Asthma Patients According to Therapy and Severity of the Disease: The BADA Study
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topic_title	Prevalence of Arterial Hypertension and Characteristics of Nocturnal Blood Pressure Profile of Asthma Patients According to Therapy and Severity of the Disease: The BADA Study asthma cardiovascular risk essential hypertension inhaled corticosteroid therapy nocturnal dipping of blood pressure
topic	misc asthma misc cardiovascular risk misc essential hypertension misc inhaled corticosteroid therapy misc nocturnal dipping of blood pressure misc Medicine misc R
topic_unstemmed	misc asthma misc cardiovascular risk misc essential hypertension misc inhaled corticosteroid therapy misc nocturnal dipping of blood pressure misc Medicine misc R
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title_full	Prevalence of Arterial Hypertension and Characteristics of Nocturnal Blood Pressure Profile of Asthma Patients According to Therapy and Severity of the Disease: The BADA Study
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title_sort	prevalence of arterial hypertension and characteristics of nocturnal blood pressure profile of asthma patients according to therapy and severity of the disease: the bada study
title_auth	Prevalence of Arterial Hypertension and Characteristics of Nocturnal Blood Pressure Profile of Asthma Patients According to Therapy and Severity of the Disease: The BADA Study
abstract	Background: several studies report an increased risk for asthmatic subjects to develop arterial hypertension and the relationship between these two diseases, frequently co-existing, still has some unclear aspects. Methods: The BADA (blood pressure levels, clinical features and markers of subclinical cardiovascular damage of asthma patients) study is aimed to evaluate the prevalence of the cardiovascular comorbidities of asthma and their impact on the clinical outcome. The main exclusion criteria were the presence of other respiratory diseases, current smoking, any contraindication to ambulatory blood pressure monitoring (ABPM). Results: The overall percentage of asthmatics having also hypertension was 75% (30 patients) vs 45% (18 patients) of the control group (<i<p</i<: 0.012). Reduced level of FEV<sub<1 </sub<(but not inhaled steroid therapy) was associated to newly-diagnosed hypertension (<i<p</i<: 0.0002), higher day SBP levels (<i<p</i<: 0.003), higher day DBP levels (<i<p</i<: 0.03), higher 24 h-SBP levels (<i<p</i<: 0.005) and higher 24h-DBP levels (<i<p</i<: 0.03). The regression analysis performed taking into account sex, age, diabetes, fasting glucose, and body mass index confirms the independent role played by asthma: odds ratio (OR): 3.66 (CI: 1.29–11.1). Conclusions: hypertension is highly prevalent in asthma; the use of ABPM has allowed the detection of a considerable number of unrecognized hypertensives.
abstractGer	Background: several studies report an increased risk for asthmatic subjects to develop arterial hypertension and the relationship between these two diseases, frequently co-existing, still has some unclear aspects. Methods: The BADA (blood pressure levels, clinical features and markers of subclinical cardiovascular damage of asthma patients) study is aimed to evaluate the prevalence of the cardiovascular comorbidities of asthma and their impact on the clinical outcome. The main exclusion criteria were the presence of other respiratory diseases, current smoking, any contraindication to ambulatory blood pressure monitoring (ABPM). Results: The overall percentage of asthmatics having also hypertension was 75% (30 patients) vs 45% (18 patients) of the control group (<i<p</i<: 0.012). Reduced level of FEV<sub<1 </sub<(but not inhaled steroid therapy) was associated to newly-diagnosed hypertension (<i<p</i<: 0.0002), higher day SBP levels (<i<p</i<: 0.003), higher day DBP levels (<i<p</i<: 0.03), higher 24 h-SBP levels (<i<p</i<: 0.005) and higher 24h-DBP levels (<i<p</i<: 0.03). The regression analysis performed taking into account sex, age, diabetes, fasting glucose, and body mass index confirms the independent role played by asthma: odds ratio (OR): 3.66 (CI: 1.29–11.1). Conclusions: hypertension is highly prevalent in asthma; the use of ABPM has allowed the detection of a considerable number of unrecognized hypertensives.
abstract_unstemmed	Background: several studies report an increased risk for asthmatic subjects to develop arterial hypertension and the relationship between these two diseases, frequently co-existing, still has some unclear aspects. Methods: The BADA (blood pressure levels, clinical features and markers of subclinical cardiovascular damage of asthma patients) study is aimed to evaluate the prevalence of the cardiovascular comorbidities of asthma and their impact on the clinical outcome. The main exclusion criteria were the presence of other respiratory diseases, current smoking, any contraindication to ambulatory blood pressure monitoring (ABPM). Results: The overall percentage of asthmatics having also hypertension was 75% (30 patients) vs 45% (18 patients) of the control group (<i<p</i<: 0.012). Reduced level of FEV<sub<1 </sub<(but not inhaled steroid therapy) was associated to newly-diagnosed hypertension (<i<p</i<: 0.0002), higher day SBP levels (<i<p</i<: 0.003), higher day DBP levels (<i<p</i<: 0.03), higher 24 h-SBP levels (<i<p</i<: 0.005) and higher 24h-DBP levels (<i<p</i<: 0.03). The regression analysis performed taking into account sex, age, diabetes, fasting glucose, and body mass index confirms the independent role played by asthma: odds ratio (OR): 3.66 (CI: 1.29–11.1). Conclusions: hypertension is highly prevalent in asthma; the use of ABPM has allowed the detection of a considerable number of unrecognized hypertensives.
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title_short	Prevalence of Arterial Hypertension and Characteristics of Nocturnal Blood Pressure Profile of Asthma Patients According to Therapy and Severity of the Disease: The BADA Study
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Methods: The BADA (blood pressure levels, clinical features and markers of subclinical cardiovascular damage of asthma patients) study is aimed to evaluate the prevalence of the cardiovascular comorbidities of asthma and their impact on the clinical outcome. The main exclusion criteria were the presence of other respiratory diseases, current smoking, any contraindication to ambulatory blood pressure monitoring (ABPM). Results: The overall percentage of asthmatics having also hypertension was 75% (30 patients) vs 45% (18 patients) of the control group (<i<p</i<: 0.012). Reduced level of FEV<sub<1 </sub<(but not inhaled steroid therapy) was associated to newly-diagnosed hypertension (<i<p</i<: 0.0002), higher day SBP levels (<i<p</i<: 0.003), higher day DBP levels (<i<p</i<: 0.03), higher 24 h-SBP levels (<i<p</i<: 0.005) and higher 24h-DBP levels (<i<p</i<: 0.03). The regression analysis performed taking into account sex, age, diabetes, fasting glucose, and body mass index confirms the independent role played by asthma: odds ratio (OR): 3.66 (CI: 1.29–11.1). 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Prevalence of Arterial Hypertension and Characteristics of Nocturnal Blood Pressure Profile of Asthma Patients According to Therapy and Severity of the Disease: The BADA Study

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