Expression-profiling of apoptosis induced by ablation of the long ncRNA TRPM2-AS in prostate cancer cell

We recently identified the long non-coding RNA (ncRNA) TRPM2-AS as a key regulator of survival in prostate cancer [1]. This essential role, coupled to the TRPM2-AS low-expression levels in healthy tissues, makes this ncRNA a suitable therapeutic target for further clinical studies. To get insights i...
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Gespeichert in:

Autor*in:	Giovanni Lavorgna [verfasserIn] Fulvio Chiacchiera [verfasserIn] Alberto Briganti [verfasserIn] Francesco Montorsi [verfasserIn] Diego Pasini [verfasserIn] Andrea Salonia [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2015

Schlagwörter:	Prostate cancer ncRNA Apoptosis Microarray Ion channel

Übergeordnetes Werk:	In: Genomics Data - Elsevier, 2015, 3(2015), C, Seite 4-5
Übergeordnetes Werk:	volume:3 ; year:2015 ; number:C ; pages:4-5

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1016/j.gdata.2014.10.020

Katalog-ID:	DOAJ042313686

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allfieldsGer	10.1016/j.gdata.2014.10.020 doi (DE-627)DOAJ042313686 (DE-599)DOAJ488063789c044291b25d8597646e6e43 DE-627 ger DE-627 rakwb eng QH426-470 Giovanni Lavorgna verfasserin aut Expression-profiling of apoptosis induced by ablation of the long ncRNA TRPM2-AS in prostate cancer cell 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier We recently identified the long non-coding RNA (ncRNA) TRPM2-AS as a key regulator of survival in prostate cancer [1]. This essential role, coupled to the TRPM2-AS low-expression levels in healthy tissues, makes this ncRNA a suitable therapeutic target for further clinical studies. To get insights into the survival mechanism controlled by this molecule, we ablated its expression in prostate cancer cells and performed a genome-wide analysis of the transcripts differentially regulated in dying cells. Here, we describe in detail the experimental system, methods and quality control for the generation of the microarray data associated with our recent publication [1]. The data are related to [1]. Data have been deposited to the Gene Expression Omnibus (GEO) database repository with the dataset identifier GSE40687. Prostate cancer ncRNA Apoptosis Microarray Ion channel Genetics Fulvio Chiacchiera verfasserin aut Alberto Briganti verfasserin aut Francesco Montorsi verfasserin aut Diego Pasini verfasserin aut Andrea Salonia verfasserin aut In Genomics Data Elsevier, 2015 3(2015), C, Seite 4-5 (DE-627)77685531X (DE-600)2751131-5 22135960 nnns volume:3 year:2015 number:C pages:4-5 https://doi.org/10.1016/j.gdata.2014.10.020 kostenfrei https://doaj.org/article/488063789c044291b25d8597646e6e43 kostenfrei http://www.sciencedirect.com/science/article/pii/S2213596014001093 kostenfrei https://doaj.org/toc/2213-5960 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 3 2015 C 4-5
allfieldsSound	10.1016/j.gdata.2014.10.020 doi (DE-627)DOAJ042313686 (DE-599)DOAJ488063789c044291b25d8597646e6e43 DE-627 ger DE-627 rakwb eng QH426-470 Giovanni Lavorgna verfasserin aut Expression-profiling of apoptosis induced by ablation of the long ncRNA TRPM2-AS in prostate cancer cell 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier We recently identified the long non-coding RNA (ncRNA) TRPM2-AS as a key regulator of survival in prostate cancer [1]. This essential role, coupled to the TRPM2-AS low-expression levels in healthy tissues, makes this ncRNA a suitable therapeutic target for further clinical studies. To get insights into the survival mechanism controlled by this molecule, we ablated its expression in prostate cancer cells and performed a genome-wide analysis of the transcripts differentially regulated in dying cells. Here, we describe in detail the experimental system, methods and quality control for the generation of the microarray data associated with our recent publication [1]. The data are related to [1]. Data have been deposited to the Gene Expression Omnibus (GEO) database repository with the dataset identifier GSE40687. Prostate cancer ncRNA Apoptosis Microarray Ion channel Genetics Fulvio Chiacchiera verfasserin aut Alberto Briganti verfasserin aut Francesco Montorsi verfasserin aut Diego Pasini verfasserin aut Andrea Salonia verfasserin aut In Genomics Data Elsevier, 2015 3(2015), C, Seite 4-5 (DE-627)77685531X (DE-600)2751131-5 22135960 nnns volume:3 year:2015 number:C pages:4-5 https://doi.org/10.1016/j.gdata.2014.10.020 kostenfrei https://doaj.org/article/488063789c044291b25d8597646e6e43 kostenfrei http://www.sciencedirect.com/science/article/pii/S2213596014001093 kostenfrei https://doaj.org/toc/2213-5960 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 3 2015 C 4-5
language	English
source	In Genomics Data 3(2015), C, Seite 4-5 volume:3 year:2015 number:C pages:4-5
sourceStr	In Genomics Data 3(2015), C, Seite 4-5 volume:3 year:2015 number:C pages:4-5
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topic_facet	Prostate cancer ncRNA Apoptosis Microarray Ion channel Genetics
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container_title	Genomics Data
authorswithroles_txt_mv	Giovanni Lavorgna @@aut@@ Fulvio Chiacchiera @@aut@@ Alberto Briganti @@aut@@ Francesco Montorsi @@aut@@ Diego Pasini @@aut@@ Andrea Salonia @@aut@@
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callnumber-first	Q - Science
author	Giovanni Lavorgna
spellingShingle	Giovanni Lavorgna misc QH426-470 misc Prostate cancer misc ncRNA misc Apoptosis misc Microarray misc Ion channel misc Genetics Expression-profiling of apoptosis induced by ablation of the long ncRNA TRPM2-AS in prostate cancer cell
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topic_title	QH426-470 Expression-profiling of apoptosis induced by ablation of the long ncRNA TRPM2-AS in prostate cancer cell Prostate cancer ncRNA Apoptosis Microarray Ion channel
topic	misc QH426-470 misc Prostate cancer misc ncRNA misc Apoptosis misc Microarray misc Ion channel misc Genetics
topic_unstemmed	misc QH426-470 misc Prostate cancer misc ncRNA misc Apoptosis misc Microarray misc Ion channel misc Genetics
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title	Expression-profiling of apoptosis induced by ablation of the long ncRNA TRPM2-AS in prostate cancer cell
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title_full	Expression-profiling of apoptosis induced by ablation of the long ncRNA TRPM2-AS in prostate cancer cell
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title_sort	expression-profiling of apoptosis induced by ablation of the long ncrna trpm2-as in prostate cancer cell
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title_auth	Expression-profiling of apoptosis induced by ablation of the long ncRNA TRPM2-AS in prostate cancer cell
abstract	We recently identified the long non-coding RNA (ncRNA) TRPM2-AS as a key regulator of survival in prostate cancer [1]. This essential role, coupled to the TRPM2-AS low-expression levels in healthy tissues, makes this ncRNA a suitable therapeutic target for further clinical studies. To get insights into the survival mechanism controlled by this molecule, we ablated its expression in prostate cancer cells and performed a genome-wide analysis of the transcripts differentially regulated in dying cells. Here, we describe in detail the experimental system, methods and quality control for the generation of the microarray data associated with our recent publication [1]. The data are related to [1]. Data have been deposited to the Gene Expression Omnibus (GEO) database repository with the dataset identifier GSE40687.
abstractGer	We recently identified the long non-coding RNA (ncRNA) TRPM2-AS as a key regulator of survival in prostate cancer [1]. This essential role, coupled to the TRPM2-AS low-expression levels in healthy tissues, makes this ncRNA a suitable therapeutic target for further clinical studies. To get insights into the survival mechanism controlled by this molecule, we ablated its expression in prostate cancer cells and performed a genome-wide analysis of the transcripts differentially regulated in dying cells. Here, we describe in detail the experimental system, methods and quality control for the generation of the microarray data associated with our recent publication [1]. The data are related to [1]. Data have been deposited to the Gene Expression Omnibus (GEO) database repository with the dataset identifier GSE40687.
abstract_unstemmed	We recently identified the long non-coding RNA (ncRNA) TRPM2-AS as a key regulator of survival in prostate cancer [1]. This essential role, coupled to the TRPM2-AS low-expression levels in healthy tissues, makes this ncRNA a suitable therapeutic target for further clinical studies. To get insights into the survival mechanism controlled by this molecule, we ablated its expression in prostate cancer cells and performed a genome-wide analysis of the transcripts differentially regulated in dying cells. Here, we describe in detail the experimental system, methods and quality control for the generation of the microarray data associated with our recent publication [1]. The data are related to [1]. Data have been deposited to the Gene Expression Omnibus (GEO) database repository with the dataset identifier GSE40687.
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title_short	Expression-profiling of apoptosis induced by ablation of the long ncRNA TRPM2-AS in prostate cancer cell
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