Fermented Feed Supplement Relieves Caecal Microbiota Dysbiosis and Kidney Injury Caused by High-Protein Diet in the Development of Gosling Gout

Firstly, forty-eight 1-day-old goslings were randomly allocated to four groups and were fed diets containing crude protein (CP) at different concentrations: 160, 180, 200, and 220 g/kg in Experiment One. We found a dose-dependent relationship between the dietary protein levels and morbidity of gosli...
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Autor*in:	Yumeng Xi [verfasserIn] Yuanpi Huang [verfasserIn] Ying Li [verfasserIn] Junshu Yan [verfasserIn] Zhendan Shi [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2020

Schlagwörter:	fermented feed gosling gout high-protein diet kidney injury caecal microbiota dysbiosis

Übergeordnetes Werk:	In: Animals - MDPI AG, 2011, 10(2020), 11, p 2139
Übergeordnetes Werk:	volume:10 ; year:2020 ; number:11, p 2139

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/ani10112139

Katalog-ID:	DOAJ042775167

Internformat


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520			\|a Firstly, forty-eight 1-day-old goslings were randomly allocated to four groups and were fed diets containing crude protein (CP) at different concentrations: 160, 180, 200, and 220 g/kg in Experiment One. We found a dose-dependent relationship between the dietary protein levels and morbidity of gosling gout. The concentration of serum uric acid (UA), creatinine (Cr), and urea nitrogen (UN), and the activity of xanthine oxidase in the 220CP groups were significantly higher than those in the low-protein diet groups. Beneficial microbes, including <i<Akkermansia</i<, <i<Lactococcus</i<, and <i<Butyricicoccus</i< were enriched in the ceca of healthy goslings, while the microbes <i<Enterococcus</i<, Enterobacteriaceae, and <i<Bacteroides</i< were enriched in those with gout. Then, we explored the effects of fermented feed on gosling gout caused by high-protein diets in Experiment Two. A total of 720 1-day-old goslings were randomly allotted to four experimental groups: CN (162.9 g/kg CP), CNF (167.5 g/kg CP, replacing 50 g/kg of the basal diet with fermented feed), HP (229.7 g/kg CP, a high-protein diet), and HPF (230.7 g/kg CP, replacing 50 g/kg of the high-protein diet with fermented feed). We found that the cumulative incidence of gout increased in the HP group compared with that in the control, but decreased in the HPF group compared to that in the HP group. Similarly, the concentration of serum UA in the HP group was higher than that in the CN group, but decreased in the HPF group. Meanwhile, compared with the HP group, using fermented feed in diets decreased the abundance of <i<Enterococcus</i< in the ceca of goslings, while increasing the abundance of <i<Lactobacillus</i<. These results suggest that appropriate dietary protein levels and the fermented feed supplement might relieve the kidney injury and gut microbiota dysbiosis caused by high-protein diets in the development of gosling gout.
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allfields	10.3390/ani10112139 doi (DE-627)DOAJ042775167 (DE-599)DOAJc15836a2ecfe470bb9b461836edfb75f DE-627 ger DE-627 rakwb eng SF600-1100 QL1-991 Yumeng Xi verfasserin aut Fermented Feed Supplement Relieves Caecal Microbiota Dysbiosis and Kidney Injury Caused by High-Protein Diet in the Development of Gosling Gout 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Firstly, forty-eight 1-day-old goslings were randomly allocated to four groups and were fed diets containing crude protein (CP) at different concentrations: 160, 180, 200, and 220 g/kg in Experiment One. We found a dose-dependent relationship between the dietary protein levels and morbidity of gosling gout. The concentration of serum uric acid (UA), creatinine (Cr), and urea nitrogen (UN), and the activity of xanthine oxidase in the 220CP groups were significantly higher than those in the low-protein diet groups. Beneficial microbes, including <i<Akkermansia</i<, <i<Lactococcus</i<, and <i<Butyricicoccus</i< were enriched in the ceca of healthy goslings, while the microbes <i<Enterococcus</i<, Enterobacteriaceae, and <i<Bacteroides</i< were enriched in those with gout. Then, we explored the effects of fermented feed on gosling gout caused by high-protein diets in Experiment Two. A total of 720 1-day-old goslings were randomly allotted to four experimental groups: CN (162.9 g/kg CP), CNF (167.5 g/kg CP, replacing 50 g/kg of the basal diet with fermented feed), HP (229.7 g/kg CP, a high-protein diet), and HPF (230.7 g/kg CP, replacing 50 g/kg of the high-protein diet with fermented feed). We found that the cumulative incidence of gout increased in the HP group compared with that in the control, but decreased in the HPF group compared to that in the HP group. Similarly, the concentration of serum UA in the HP group was higher than that in the CN group, but decreased in the HPF group. Meanwhile, compared with the HP group, using fermented feed in diets decreased the abundance of <i<Enterococcus</i< in the ceca of goslings, while increasing the abundance of <i<Lactobacillus</i<. These results suggest that appropriate dietary protein levels and the fermented feed supplement might relieve the kidney injury and gut microbiota dysbiosis caused by high-protein diets in the development of gosling gout. fermented feed gosling gout high-protein diet kidney injury caecal microbiota dysbiosis Veterinary medicine Zoology Yuanpi Huang verfasserin aut Ying Li verfasserin aut Junshu Yan verfasserin aut Zhendan Shi verfasserin aut In Animals MDPI AG, 2011 10(2020), 11, p 2139 (DE-627)657589306 (DE-600)2606558-7 20762615 nnns volume:10 year:2020 number:11, p 2139 https://doi.org/10.3390/ani10112139 kostenfrei https://doaj.org/article/c15836a2ecfe470bb9b461836edfb75f kostenfrei https://www.mdpi.com/2076-2615/10/11/2139 kostenfrei https://doaj.org/toc/2076-2615 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2020 11, p 2139
spelling	10.3390/ani10112139 doi (DE-627)DOAJ042775167 (DE-599)DOAJc15836a2ecfe470bb9b461836edfb75f DE-627 ger DE-627 rakwb eng SF600-1100 QL1-991 Yumeng Xi verfasserin aut Fermented Feed Supplement Relieves Caecal Microbiota Dysbiosis and Kidney Injury Caused by High-Protein Diet in the Development of Gosling Gout 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Firstly, forty-eight 1-day-old goslings were randomly allocated to four groups and were fed diets containing crude protein (CP) at different concentrations: 160, 180, 200, and 220 g/kg in Experiment One. We found a dose-dependent relationship between the dietary protein levels and morbidity of gosling gout. The concentration of serum uric acid (UA), creatinine (Cr), and urea nitrogen (UN), and the activity of xanthine oxidase in the 220CP groups were significantly higher than those in the low-protein diet groups. Beneficial microbes, including <i<Akkermansia</i<, <i<Lactococcus</i<, and <i<Butyricicoccus</i< were enriched in the ceca of healthy goslings, while the microbes <i<Enterococcus</i<, Enterobacteriaceae, and <i<Bacteroides</i< were enriched in those with gout. Then, we explored the effects of fermented feed on gosling gout caused by high-protein diets in Experiment Two. A total of 720 1-day-old goslings were randomly allotted to four experimental groups: CN (162.9 g/kg CP), CNF (167.5 g/kg CP, replacing 50 g/kg of the basal diet with fermented feed), HP (229.7 g/kg CP, a high-protein diet), and HPF (230.7 g/kg CP, replacing 50 g/kg of the high-protein diet with fermented feed). We found that the cumulative incidence of gout increased in the HP group compared with that in the control, but decreased in the HPF group compared to that in the HP group. Similarly, the concentration of serum UA in the HP group was higher than that in the CN group, but decreased in the HPF group. Meanwhile, compared with the HP group, using fermented feed in diets decreased the abundance of <i<Enterococcus</i< in the ceca of goslings, while increasing the abundance of <i<Lactobacillus</i<. These results suggest that appropriate dietary protein levels and the fermented feed supplement might relieve the kidney injury and gut microbiota dysbiosis caused by high-protein diets in the development of gosling gout. fermented feed gosling gout high-protein diet kidney injury caecal microbiota dysbiosis Veterinary medicine Zoology Yuanpi Huang verfasserin aut Ying Li verfasserin aut Junshu Yan verfasserin aut Zhendan Shi verfasserin aut In Animals MDPI AG, 2011 10(2020), 11, p 2139 (DE-627)657589306 (DE-600)2606558-7 20762615 nnns volume:10 year:2020 number:11, p 2139 https://doi.org/10.3390/ani10112139 kostenfrei https://doaj.org/article/c15836a2ecfe470bb9b461836edfb75f kostenfrei https://www.mdpi.com/2076-2615/10/11/2139 kostenfrei https://doaj.org/toc/2076-2615 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2020 11, p 2139
allfields_unstemmed	10.3390/ani10112139 doi (DE-627)DOAJ042775167 (DE-599)DOAJc15836a2ecfe470bb9b461836edfb75f DE-627 ger DE-627 rakwb eng SF600-1100 QL1-991 Yumeng Xi verfasserin aut Fermented Feed Supplement Relieves Caecal Microbiota Dysbiosis and Kidney Injury Caused by High-Protein Diet in the Development of Gosling Gout 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Firstly, forty-eight 1-day-old goslings were randomly allocated to four groups and were fed diets containing crude protein (CP) at different concentrations: 160, 180, 200, and 220 g/kg in Experiment One. We found a dose-dependent relationship between the dietary protein levels and morbidity of gosling gout. The concentration of serum uric acid (UA), creatinine (Cr), and urea nitrogen (UN), and the activity of xanthine oxidase in the 220CP groups were significantly higher than those in the low-protein diet groups. Beneficial microbes, including <i<Akkermansia</i<, <i<Lactococcus</i<, and <i<Butyricicoccus</i< were enriched in the ceca of healthy goslings, while the microbes <i<Enterococcus</i<, Enterobacteriaceae, and <i<Bacteroides</i< were enriched in those with gout. Then, we explored the effects of fermented feed on gosling gout caused by high-protein diets in Experiment Two. A total of 720 1-day-old goslings were randomly allotted to four experimental groups: CN (162.9 g/kg CP), CNF (167.5 g/kg CP, replacing 50 g/kg of the basal diet with fermented feed), HP (229.7 g/kg CP, a high-protein diet), and HPF (230.7 g/kg CP, replacing 50 g/kg of the high-protein diet with fermented feed). We found that the cumulative incidence of gout increased in the HP group compared with that in the control, but decreased in the HPF group compared to that in the HP group. Similarly, the concentration of serum UA in the HP group was higher than that in the CN group, but decreased in the HPF group. Meanwhile, compared with the HP group, using fermented feed in diets decreased the abundance of <i<Enterococcus</i< in the ceca of goslings, while increasing the abundance of <i<Lactobacillus</i<. These results suggest that appropriate dietary protein levels and the fermented feed supplement might relieve the kidney injury and gut microbiota dysbiosis caused by high-protein diets in the development of gosling gout. fermented feed gosling gout high-protein diet kidney injury caecal microbiota dysbiosis Veterinary medicine Zoology Yuanpi Huang verfasserin aut Ying Li verfasserin aut Junshu Yan verfasserin aut Zhendan Shi verfasserin aut In Animals MDPI AG, 2011 10(2020), 11, p 2139 (DE-627)657589306 (DE-600)2606558-7 20762615 nnns volume:10 year:2020 number:11, p 2139 https://doi.org/10.3390/ani10112139 kostenfrei https://doaj.org/article/c15836a2ecfe470bb9b461836edfb75f kostenfrei https://www.mdpi.com/2076-2615/10/11/2139 kostenfrei https://doaj.org/toc/2076-2615 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2020 11, p 2139
allfieldsGer	10.3390/ani10112139 doi (DE-627)DOAJ042775167 (DE-599)DOAJc15836a2ecfe470bb9b461836edfb75f DE-627 ger DE-627 rakwb eng SF600-1100 QL1-991 Yumeng Xi verfasserin aut Fermented Feed Supplement Relieves Caecal Microbiota Dysbiosis and Kidney Injury Caused by High-Protein Diet in the Development of Gosling Gout 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Firstly, forty-eight 1-day-old goslings were randomly allocated to four groups and were fed diets containing crude protein (CP) at different concentrations: 160, 180, 200, and 220 g/kg in Experiment One. We found a dose-dependent relationship between the dietary protein levels and morbidity of gosling gout. The concentration of serum uric acid (UA), creatinine (Cr), and urea nitrogen (UN), and the activity of xanthine oxidase in the 220CP groups were significantly higher than those in the low-protein diet groups. Beneficial microbes, including <i<Akkermansia</i<, <i<Lactococcus</i<, and <i<Butyricicoccus</i< were enriched in the ceca of healthy goslings, while the microbes <i<Enterococcus</i<, Enterobacteriaceae, and <i<Bacteroides</i< were enriched in those with gout. Then, we explored the effects of fermented feed on gosling gout caused by high-protein diets in Experiment Two. A total of 720 1-day-old goslings were randomly allotted to four experimental groups: CN (162.9 g/kg CP), CNF (167.5 g/kg CP, replacing 50 g/kg of the basal diet with fermented feed), HP (229.7 g/kg CP, a high-protein diet), and HPF (230.7 g/kg CP, replacing 50 g/kg of the high-protein diet with fermented feed). We found that the cumulative incidence of gout increased in the HP group compared with that in the control, but decreased in the HPF group compared to that in the HP group. Similarly, the concentration of serum UA in the HP group was higher than that in the CN group, but decreased in the HPF group. Meanwhile, compared with the HP group, using fermented feed in diets decreased the abundance of <i<Enterococcus</i< in the ceca of goslings, while increasing the abundance of <i<Lactobacillus</i<. These results suggest that appropriate dietary protein levels and the fermented feed supplement might relieve the kidney injury and gut microbiota dysbiosis caused by high-protein diets in the development of gosling gout. fermented feed gosling gout high-protein diet kidney injury caecal microbiota dysbiosis Veterinary medicine Zoology Yuanpi Huang verfasserin aut Ying Li verfasserin aut Junshu Yan verfasserin aut Zhendan Shi verfasserin aut In Animals MDPI AG, 2011 10(2020), 11, p 2139 (DE-627)657589306 (DE-600)2606558-7 20762615 nnns volume:10 year:2020 number:11, p 2139 https://doi.org/10.3390/ani10112139 kostenfrei https://doaj.org/article/c15836a2ecfe470bb9b461836edfb75f kostenfrei https://www.mdpi.com/2076-2615/10/11/2139 kostenfrei https://doaj.org/toc/2076-2615 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2020 11, p 2139
allfieldsSound	10.3390/ani10112139 doi (DE-627)DOAJ042775167 (DE-599)DOAJc15836a2ecfe470bb9b461836edfb75f DE-627 ger DE-627 rakwb eng SF600-1100 QL1-991 Yumeng Xi verfasserin aut Fermented Feed Supplement Relieves Caecal Microbiota Dysbiosis and Kidney Injury Caused by High-Protein Diet in the Development of Gosling Gout 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Firstly, forty-eight 1-day-old goslings were randomly allocated to four groups and were fed diets containing crude protein (CP) at different concentrations: 160, 180, 200, and 220 g/kg in Experiment One. We found a dose-dependent relationship between the dietary protein levels and morbidity of gosling gout. The concentration of serum uric acid (UA), creatinine (Cr), and urea nitrogen (UN), and the activity of xanthine oxidase in the 220CP groups were significantly higher than those in the low-protein diet groups. Beneficial microbes, including <i<Akkermansia</i<, <i<Lactococcus</i<, and <i<Butyricicoccus</i< were enriched in the ceca of healthy goslings, while the microbes <i<Enterococcus</i<, Enterobacteriaceae, and <i<Bacteroides</i< were enriched in those with gout. Then, we explored the effects of fermented feed on gosling gout caused by high-protein diets in Experiment Two. A total of 720 1-day-old goslings were randomly allotted to four experimental groups: CN (162.9 g/kg CP), CNF (167.5 g/kg CP, replacing 50 g/kg of the basal diet with fermented feed), HP (229.7 g/kg CP, a high-protein diet), and HPF (230.7 g/kg CP, replacing 50 g/kg of the high-protein diet with fermented feed). We found that the cumulative incidence of gout increased in the HP group compared with that in the control, but decreased in the HPF group compared to that in the HP group. Similarly, the concentration of serum UA in the HP group was higher than that in the CN group, but decreased in the HPF group. Meanwhile, compared with the HP group, using fermented feed in diets decreased the abundance of <i<Enterococcus</i< in the ceca of goslings, while increasing the abundance of <i<Lactobacillus</i<. These results suggest that appropriate dietary protein levels and the fermented feed supplement might relieve the kidney injury and gut microbiota dysbiosis caused by high-protein diets in the development of gosling gout. fermented feed gosling gout high-protein diet kidney injury caecal microbiota dysbiosis Veterinary medicine Zoology Yuanpi Huang verfasserin aut Ying Li verfasserin aut Junshu Yan verfasserin aut Zhendan Shi verfasserin aut In Animals MDPI AG, 2011 10(2020), 11, p 2139 (DE-627)657589306 (DE-600)2606558-7 20762615 nnns volume:10 year:2020 number:11, p 2139 https://doi.org/10.3390/ani10112139 kostenfrei https://doaj.org/article/c15836a2ecfe470bb9b461836edfb75f kostenfrei https://www.mdpi.com/2076-2615/10/11/2139 kostenfrei https://doaj.org/toc/2076-2615 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2020 11, p 2139
language	English
source	In Animals 10(2020), 11, p 2139 volume:10 year:2020 number:11, p 2139
sourceStr	In Animals 10(2020), 11, p 2139 volume:10 year:2020 number:11, p 2139
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	fermented feed gosling gout high-protein diet kidney injury caecal microbiota dysbiosis Veterinary medicine Zoology
isfreeaccess_bool	true
container_title	Animals
authorswithroles_txt_mv	Yumeng Xi @@aut@@ Yuanpi Huang @@aut@@ Ying Li @@aut@@ Junshu Yan @@aut@@ Zhendan Shi @@aut@@
publishDateDaySort_date	2020-01-01T00:00:00Z
hierarchy_top_id	657589306
id	DOAJ042775167
language_de	englisch
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A total of 720 1-day-old goslings were randomly allotted to four experimental groups: CN (162.9 g/kg CP), CNF (167.5 g/kg CP, replacing 50 g/kg of the basal diet with fermented feed), HP (229.7 g/kg CP, a high-protein diet), and HPF (230.7 g/kg CP, replacing 50 g/kg of the high-protein diet with fermented feed). We found that the cumulative incidence of gout increased in the HP group compared with that in the control, but decreased in the HPF group compared to that in the HP group. Similarly, the concentration of serum UA in the HP group was higher than that in the CN group, but decreased in the HPF group. Meanwhile, compared with the HP group, using fermented feed in diets decreased the abundance of <i<Enterococcus</i< in the ceca of goslings, while increasing the abundance of <i<Lactobacillus</i<. 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callnumber-first	S - Agriculture
author	Yumeng Xi
spellingShingle	Yumeng Xi misc SF600-1100 misc QL1-991 misc fermented feed misc gosling gout misc high-protein diet misc kidney injury misc caecal microbiota dysbiosis misc Veterinary medicine misc Zoology Fermented Feed Supplement Relieves Caecal Microbiota Dysbiosis and Kidney Injury Caused by High-Protein Diet in the Development of Gosling Gout
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topic_title	SF600-1100 QL1-991 Fermented Feed Supplement Relieves Caecal Microbiota Dysbiosis and Kidney Injury Caused by High-Protein Diet in the Development of Gosling Gout fermented feed gosling gout high-protein diet kidney injury caecal microbiota dysbiosis
topic	misc SF600-1100 misc QL1-991 misc fermented feed misc gosling gout misc high-protein diet misc kidney injury misc caecal microbiota dysbiosis misc Veterinary medicine misc Zoology
topic_unstemmed	misc SF600-1100 misc QL1-991 misc fermented feed misc gosling gout misc high-protein diet misc kidney injury misc caecal microbiota dysbiosis misc Veterinary medicine misc Zoology
topic_browse	misc SF600-1100 misc QL1-991 misc fermented feed misc gosling gout misc high-protein diet misc kidney injury misc caecal microbiota dysbiosis misc Veterinary medicine misc Zoology
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title	Fermented Feed Supplement Relieves Caecal Microbiota Dysbiosis and Kidney Injury Caused by High-Protein Diet in the Development of Gosling Gout
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title_full	Fermented Feed Supplement Relieves Caecal Microbiota Dysbiosis and Kidney Injury Caused by High-Protein Diet in the Development of Gosling Gout
author_sort	Yumeng Xi
journal	Animals
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author_browse	Yumeng Xi Yuanpi Huang Ying Li Junshu Yan Zhendan Shi
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author-letter	Yumeng Xi
doi_str_mv	10.3390/ani10112139
author2-role	verfasserin
title_sort	fermented feed supplement relieves caecal microbiota dysbiosis and kidney injury caused by high-protein diet in the development of gosling gout
callnumber	SF600-1100
title_auth	Fermented Feed Supplement Relieves Caecal Microbiota Dysbiosis and Kidney Injury Caused by High-Protein Diet in the Development of Gosling Gout
abstract	Firstly, forty-eight 1-day-old goslings were randomly allocated to four groups and were fed diets containing crude protein (CP) at different concentrations: 160, 180, 200, and 220 g/kg in Experiment One. We found a dose-dependent relationship between the dietary protein levels and morbidity of gosling gout. The concentration of serum uric acid (UA), creatinine (Cr), and urea nitrogen (UN), and the activity of xanthine oxidase in the 220CP groups were significantly higher than those in the low-protein diet groups. Beneficial microbes, including <i<Akkermansia</i<, <i<Lactococcus</i<, and <i<Butyricicoccus</i< were enriched in the ceca of healthy goslings, while the microbes <i<Enterococcus</i<, Enterobacteriaceae, and <i<Bacteroides</i< were enriched in those with gout. Then, we explored the effects of fermented feed on gosling gout caused by high-protein diets in Experiment Two. A total of 720 1-day-old goslings were randomly allotted to four experimental groups: CN (162.9 g/kg CP), CNF (167.5 g/kg CP, replacing 50 g/kg of the basal diet with fermented feed), HP (229.7 g/kg CP, a high-protein diet), and HPF (230.7 g/kg CP, replacing 50 g/kg of the high-protein diet with fermented feed). We found that the cumulative incidence of gout increased in the HP group compared with that in the control, but decreased in the HPF group compared to that in the HP group. Similarly, the concentration of serum UA in the HP group was higher than that in the CN group, but decreased in the HPF group. Meanwhile, compared with the HP group, using fermented feed in diets decreased the abundance of <i<Enterococcus</i< in the ceca of goslings, while increasing the abundance of <i<Lactobacillus</i<. These results suggest that appropriate dietary protein levels and the fermented feed supplement might relieve the kidney injury and gut microbiota dysbiosis caused by high-protein diets in the development of gosling gout.
abstractGer	Firstly, forty-eight 1-day-old goslings were randomly allocated to four groups and were fed diets containing crude protein (CP) at different concentrations: 160, 180, 200, and 220 g/kg in Experiment One. We found a dose-dependent relationship between the dietary protein levels and morbidity of gosling gout. The concentration of serum uric acid (UA), creatinine (Cr), and urea nitrogen (UN), and the activity of xanthine oxidase in the 220CP groups were significantly higher than those in the low-protein diet groups. Beneficial microbes, including <i<Akkermansia</i<, <i<Lactococcus</i<, and <i<Butyricicoccus</i< were enriched in the ceca of healthy goslings, while the microbes <i<Enterococcus</i<, Enterobacteriaceae, and <i<Bacteroides</i< were enriched in those with gout. Then, we explored the effects of fermented feed on gosling gout caused by high-protein diets in Experiment Two. A total of 720 1-day-old goslings were randomly allotted to four experimental groups: CN (162.9 g/kg CP), CNF (167.5 g/kg CP, replacing 50 g/kg of the basal diet with fermented feed), HP (229.7 g/kg CP, a high-protein diet), and HPF (230.7 g/kg CP, replacing 50 g/kg of the high-protein diet with fermented feed). We found that the cumulative incidence of gout increased in the HP group compared with that in the control, but decreased in the HPF group compared to that in the HP group. Similarly, the concentration of serum UA in the HP group was higher than that in the CN group, but decreased in the HPF group. Meanwhile, compared with the HP group, using fermented feed in diets decreased the abundance of <i<Enterococcus</i< in the ceca of goslings, while increasing the abundance of <i<Lactobacillus</i<. These results suggest that appropriate dietary protein levels and the fermented feed supplement might relieve the kidney injury and gut microbiota dysbiosis caused by high-protein diets in the development of gosling gout.
abstract_unstemmed	Firstly, forty-eight 1-day-old goslings were randomly allocated to four groups and were fed diets containing crude protein (CP) at different concentrations: 160, 180, 200, and 220 g/kg in Experiment One. We found a dose-dependent relationship between the dietary protein levels and morbidity of gosling gout. The concentration of serum uric acid (UA), creatinine (Cr), and urea nitrogen (UN), and the activity of xanthine oxidase in the 220CP groups were significantly higher than those in the low-protein diet groups. Beneficial microbes, including <i<Akkermansia</i<, <i<Lactococcus</i<, and <i<Butyricicoccus</i< were enriched in the ceca of healthy goslings, while the microbes <i<Enterococcus</i<, Enterobacteriaceae, and <i<Bacteroides</i< were enriched in those with gout. Then, we explored the effects of fermented feed on gosling gout caused by high-protein diets in Experiment Two. A total of 720 1-day-old goslings were randomly allotted to four experimental groups: CN (162.9 g/kg CP), CNF (167.5 g/kg CP, replacing 50 g/kg of the basal diet with fermented feed), HP (229.7 g/kg CP, a high-protein diet), and HPF (230.7 g/kg CP, replacing 50 g/kg of the high-protein diet with fermented feed). We found that the cumulative incidence of gout increased in the HP group compared with that in the control, but decreased in the HPF group compared to that in the HP group. Similarly, the concentration of serum UA in the HP group was higher than that in the CN group, but decreased in the HPF group. Meanwhile, compared with the HP group, using fermented feed in diets decreased the abundance of <i<Enterococcus</i< in the ceca of goslings, while increasing the abundance of <i<Lactobacillus</i<. These results suggest that appropriate dietary protein levels and the fermented feed supplement might relieve the kidney injury and gut microbiota dysbiosis caused by high-protein diets in the development of gosling gout.
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title_short	Fermented Feed Supplement Relieves Caecal Microbiota Dysbiosis and Kidney Injury Caused by High-Protein Diet in the Development of Gosling Gout
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Fermented Feed Supplement Relieves Caecal Microbiota Dysbiosis and Kidney Injury Caused by High-Protein Diet in the Development of Gosling Gout

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