Rethinking Sesquiterpenoids: A Widespread Hormone in Animals

The sesquiterpenoid hormone juvenile hormone (JH) controls development, reproduction, and metamorphosis in insects, and has long been thought to be confined to the Insecta. While it remains true that juvenile hormone is specifically synthesized in insects, other types or forms of sesquiterpenoids ha...
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Autor*in:	Wai Lok So [verfasserIn] Zhenpeng Kai [verfasserIn] Zhe Qu [verfasserIn] William G. Bendena [verfasserIn] Jerome H. L. Hui [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022

Schlagwörter:	evolution farnesoic acid methyl farnesoate juvenile hormone insect metazoan

Übergeordnetes Werk:	In: International Journal of Molecular Sciences - MDPI AG, 2003, 23(2022), 11, p 5998
Übergeordnetes Werk:	volume:23 ; year:2022 ; number:11, p 5998

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.3390/ijms23115998

Katalog-ID:	DOAJ042877563

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allfields	10.3390/ijms23115998 doi (DE-627)DOAJ042877563 (DE-599)DOAJbf4748dcdad94f05bea248d843a715ef DE-627 ger DE-627 rakwb eng QH301-705.5 QD1-999 Wai Lok So verfasserin aut Rethinking Sesquiterpenoids: A Widespread Hormone in Animals 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The sesquiterpenoid hormone juvenile hormone (JH) controls development, reproduction, and metamorphosis in insects, and has long been thought to be confined to the Insecta. While it remains true that juvenile hormone is specifically synthesized in insects, other types or forms of sesquiterpenoids have also been discovered in distantly related animals, such as the jellyfish. Here, we combine the latest literature and annotate the sesquiterpenoid biosynthetic pathway genes in different animal genomes. We hypothesize that the sesquiterpenoid hormonal system is an ancestral system established in an animal ancestor and remains widespread in many animals. Different animal lineages have adapted different enzymatic routes from a common pathway, with cnidarians producing farnesoic acid (FA); non-insect protostomes and non-vertebrate deuterostomes such as cephalochordate and echinoderm synthesizing FA and methyl farnesoate (MF); and insects producing FA, MF, and JH. Our hypothesis revolutionizes the current view on the sesquiterpenoids in the metazoans, and forms a foundation for a re-investigation of the roles of this important and yet neglected type of hormone in different animals. evolution farnesoic acid methyl farnesoate juvenile hormone insect metazoan Biology (General) Chemistry Zhenpeng Kai verfasserin aut Zhe Qu verfasserin aut William G. Bendena verfasserin aut Jerome H. L. Hui verfasserin aut In International Journal of Molecular Sciences MDPI AG, 2003 23(2022), 11, p 5998 (DE-627)316340715 (DE-600)2019364-6 14220067 nnns volume:23 year:2022 number:11, p 5998 https://doi.org/10.3390/ijms23115998 kostenfrei https://doaj.org/article/bf4748dcdad94f05bea248d843a715ef kostenfrei https://www.mdpi.com/1422-0067/23/11/5998 kostenfrei https://doaj.org/toc/1661-6596 Journal toc kostenfrei https://doaj.org/toc/1422-0067 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 23 2022 11, p 5998
spelling	10.3390/ijms23115998 doi (DE-627)DOAJ042877563 (DE-599)DOAJbf4748dcdad94f05bea248d843a715ef DE-627 ger DE-627 rakwb eng QH301-705.5 QD1-999 Wai Lok So verfasserin aut Rethinking Sesquiterpenoids: A Widespread Hormone in Animals 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The sesquiterpenoid hormone juvenile hormone (JH) controls development, reproduction, and metamorphosis in insects, and has long been thought to be confined to the Insecta. While it remains true that juvenile hormone is specifically synthesized in insects, other types or forms of sesquiterpenoids have also been discovered in distantly related animals, such as the jellyfish. Here, we combine the latest literature and annotate the sesquiterpenoid biosynthetic pathway genes in different animal genomes. We hypothesize that the sesquiterpenoid hormonal system is an ancestral system established in an animal ancestor and remains widespread in many animals. Different animal lineages have adapted different enzymatic routes from a common pathway, with cnidarians producing farnesoic acid (FA); non-insect protostomes and non-vertebrate deuterostomes such as cephalochordate and echinoderm synthesizing FA and methyl farnesoate (MF); and insects producing FA, MF, and JH. Our hypothesis revolutionizes the current view on the sesquiterpenoids in the metazoans, and forms a foundation for a re-investigation of the roles of this important and yet neglected type of hormone in different animals. evolution farnesoic acid methyl farnesoate juvenile hormone insect metazoan Biology (General) Chemistry Zhenpeng Kai verfasserin aut Zhe Qu verfasserin aut William G. Bendena verfasserin aut Jerome H. L. Hui verfasserin aut In International Journal of Molecular Sciences MDPI AG, 2003 23(2022), 11, p 5998 (DE-627)316340715 (DE-600)2019364-6 14220067 nnns volume:23 year:2022 number:11, p 5998 https://doi.org/10.3390/ijms23115998 kostenfrei https://doaj.org/article/bf4748dcdad94f05bea248d843a715ef kostenfrei https://www.mdpi.com/1422-0067/23/11/5998 kostenfrei https://doaj.org/toc/1661-6596 Journal toc kostenfrei https://doaj.org/toc/1422-0067 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 23 2022 11, p 5998
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source	In International Journal of Molecular Sciences 23(2022), 11, p 5998 volume:23 year:2022 number:11, p 5998
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callnumber-first	Q - Science
author	Wai Lok So
spellingShingle	Wai Lok So misc QH301-705.5 misc QD1-999 misc evolution misc farnesoic acid misc methyl farnesoate misc juvenile hormone misc insect misc metazoan misc Biology (General) misc Chemistry Rethinking Sesquiterpenoids: A Widespread Hormone in Animals
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topic_title	QH301-705.5 QD1-999 Rethinking Sesquiterpenoids: A Widespread Hormone in Animals evolution farnesoic acid methyl farnesoate juvenile hormone insect metazoan
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title	Rethinking Sesquiterpenoids: A Widespread Hormone in Animals
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title_sort	rethinking sesquiterpenoids: a widespread hormone in animals
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title_auth	Rethinking Sesquiterpenoids: A Widespread Hormone in Animals
abstract	The sesquiterpenoid hormone juvenile hormone (JH) controls development, reproduction, and metamorphosis in insects, and has long been thought to be confined to the Insecta. While it remains true that juvenile hormone is specifically synthesized in insects, other types or forms of sesquiterpenoids have also been discovered in distantly related animals, such as the jellyfish. Here, we combine the latest literature and annotate the sesquiterpenoid biosynthetic pathway genes in different animal genomes. We hypothesize that the sesquiterpenoid hormonal system is an ancestral system established in an animal ancestor and remains widespread in many animals. Different animal lineages have adapted different enzymatic routes from a common pathway, with cnidarians producing farnesoic acid (FA); non-insect protostomes and non-vertebrate deuterostomes such as cephalochordate and echinoderm synthesizing FA and methyl farnesoate (MF); and insects producing FA, MF, and JH. Our hypothesis revolutionizes the current view on the sesquiterpenoids in the metazoans, and forms a foundation for a re-investigation of the roles of this important and yet neglected type of hormone in different animals.
abstractGer	The sesquiterpenoid hormone juvenile hormone (JH) controls development, reproduction, and metamorphosis in insects, and has long been thought to be confined to the Insecta. While it remains true that juvenile hormone is specifically synthesized in insects, other types or forms of sesquiterpenoids have also been discovered in distantly related animals, such as the jellyfish. Here, we combine the latest literature and annotate the sesquiterpenoid biosynthetic pathway genes in different animal genomes. We hypothesize that the sesquiterpenoid hormonal system is an ancestral system established in an animal ancestor and remains widespread in many animals. Different animal lineages have adapted different enzymatic routes from a common pathway, with cnidarians producing farnesoic acid (FA); non-insect protostomes and non-vertebrate deuterostomes such as cephalochordate and echinoderm synthesizing FA and methyl farnesoate (MF); and insects producing FA, MF, and JH. Our hypothesis revolutionizes the current view on the sesquiterpenoids in the metazoans, and forms a foundation for a re-investigation of the roles of this important and yet neglected type of hormone in different animals.
abstract_unstemmed	The sesquiterpenoid hormone juvenile hormone (JH) controls development, reproduction, and metamorphosis in insects, and has long been thought to be confined to the Insecta. While it remains true that juvenile hormone is specifically synthesized in insects, other types or forms of sesquiterpenoids have also been discovered in distantly related animals, such as the jellyfish. Here, we combine the latest literature and annotate the sesquiterpenoid biosynthetic pathway genes in different animal genomes. We hypothesize that the sesquiterpenoid hormonal system is an ancestral system established in an animal ancestor and remains widespread in many animals. Different animal lineages have adapted different enzymatic routes from a common pathway, with cnidarians producing farnesoic acid (FA); non-insect protostomes and non-vertebrate deuterostomes such as cephalochordate and echinoderm synthesizing FA and methyl farnesoate (MF); and insects producing FA, MF, and JH. Our hypothesis revolutionizes the current view on the sesquiterpenoids in the metazoans, and forms a foundation for a re-investigation of the roles of this important and yet neglected type of hormone in different animals.
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title_short	Rethinking Sesquiterpenoids: A Widespread Hormone in Animals
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Rethinking Sesquiterpenoids: A Widespread Hormone in Animals

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