Research progress of specific pro-resolving mediators in ocular surface diseases
Specific pro-resolving mediators(SPM)are a class of lipid mediators that trigger and orchestrate the resolution of inflammation, which formed in cells by the metabolism of polyunsaturated fatty acids. SPM pathway and receptors are highly expressed inocular surface, and constitute endogenous SPM netw...
Ausführliche Beschreibung
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| Autor*in: |
Li-Xian He [verfasserIn] Gang Tan [verfasserIn] |
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| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch |
| Erschienen: |
2022 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
In: Guoji Yanke Zazhi - Press of International Journal of Ophthalmology (IJO PRESS), 2017, 22(2022), 6, Seite 946-950 |
|---|---|
| Übergeordnetes Werk: |
volume:22 ; year:2022 ; number:6 ; pages:946-950 |
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10.3980/j.issn.1672-5123.2022.6.12 |
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10.3980/j.issn.1672-5123.2022.6.12 doi (DE-627)DOAJ043451985 (DE-599)DOAJ055a005bee334041b65dbd3d4c843534 DE-627 ger DE-627 rakwb eng RE1-994 Li-Xian He verfasserin aut Research progress of specific pro-resolving mediators in ocular surface diseases 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Specific pro-resolving mediators(SPM)are a class of lipid mediators that trigger and orchestrate the resolution of inflammation, which formed in cells by the metabolism of polyunsaturated fatty acids. SPM pathway and receptors are highly expressed inocular surface, and constitute endogenous SPM networks which are important for maintaining ocular surface health and immune homeostasis. Recent evidence indicates that SPM and their analogs are essential mediators in promoting corneal wound healing, corneal nerve regeneration, and inhibiting the immune inflammatory response of corneal transplant rejection, allergic conjunctivitis and microbial keratitis. In addition, they are potential therapeutic drug targets of dry eye disease, and provide novel insight on the research and treatment of ocular surface diseases. Here, we will review and discuss evidence for SPM as important endogenous regulators of ocular surface health and disease and their therapeutic potential. specific pro-resolving mediators ocular surface disease immune homeostasis inflammatory response Ophthalmology Gang Tan verfasserin aut In Guoji Yanke Zazhi Press of International Journal of Ophthalmology (IJO PRESS), 2017 22(2022), 6, Seite 946-950 (DE-627)1680946854 16725123 nnns volume:22 year:2022 number:6 pages:946-950 https://doi.org/10.3980/j.issn.1672-5123.2022.6.12 kostenfrei https://doaj.org/article/055a005bee334041b65dbd3d4c843534 kostenfrei http://ies.ijo.cn/cn_publish/2022/6/202206012.pdf kostenfrei https://doaj.org/toc/1672-5123 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_2817 AR 22 2022 6 946-950 |
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10.3980/j.issn.1672-5123.2022.6.12 doi (DE-627)DOAJ043451985 (DE-599)DOAJ055a005bee334041b65dbd3d4c843534 DE-627 ger DE-627 rakwb eng RE1-994 Li-Xian He verfasserin aut Research progress of specific pro-resolving mediators in ocular surface diseases 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Specific pro-resolving mediators(SPM)are a class of lipid mediators that trigger and orchestrate the resolution of inflammation, which formed in cells by the metabolism of polyunsaturated fatty acids. SPM pathway and receptors are highly expressed inocular surface, and constitute endogenous SPM networks which are important for maintaining ocular surface health and immune homeostasis. Recent evidence indicates that SPM and their analogs are essential mediators in promoting corneal wound healing, corneal nerve regeneration, and inhibiting the immune inflammatory response of corneal transplant rejection, allergic conjunctivitis and microbial keratitis. In addition, they are potential therapeutic drug targets of dry eye disease, and provide novel insight on the research and treatment of ocular surface diseases. Here, we will review and discuss evidence for SPM as important endogenous regulators of ocular surface health and disease and their therapeutic potential. specific pro-resolving mediators ocular surface disease immune homeostasis inflammatory response Ophthalmology Gang Tan verfasserin aut In Guoji Yanke Zazhi Press of International Journal of Ophthalmology (IJO PRESS), 2017 22(2022), 6, Seite 946-950 (DE-627)1680946854 16725123 nnns volume:22 year:2022 number:6 pages:946-950 https://doi.org/10.3980/j.issn.1672-5123.2022.6.12 kostenfrei https://doaj.org/article/055a005bee334041b65dbd3d4c843534 kostenfrei http://ies.ijo.cn/cn_publish/2022/6/202206012.pdf kostenfrei https://doaj.org/toc/1672-5123 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_2817 AR 22 2022 6 946-950 |
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10.3980/j.issn.1672-5123.2022.6.12 doi (DE-627)DOAJ043451985 (DE-599)DOAJ055a005bee334041b65dbd3d4c843534 DE-627 ger DE-627 rakwb eng RE1-994 Li-Xian He verfasserin aut Research progress of specific pro-resolving mediators in ocular surface diseases 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Specific pro-resolving mediators(SPM)are a class of lipid mediators that trigger and orchestrate the resolution of inflammation, which formed in cells by the metabolism of polyunsaturated fatty acids. SPM pathway and receptors are highly expressed inocular surface, and constitute endogenous SPM networks which are important for maintaining ocular surface health and immune homeostasis. Recent evidence indicates that SPM and their analogs are essential mediators in promoting corneal wound healing, corneal nerve regeneration, and inhibiting the immune inflammatory response of corneal transplant rejection, allergic conjunctivitis and microbial keratitis. In addition, they are potential therapeutic drug targets of dry eye disease, and provide novel insight on the research and treatment of ocular surface diseases. Here, we will review and discuss evidence for SPM as important endogenous regulators of ocular surface health and disease and their therapeutic potential. specific pro-resolving mediators ocular surface disease immune homeostasis inflammatory response Ophthalmology Gang Tan verfasserin aut In Guoji Yanke Zazhi Press of International Journal of Ophthalmology (IJO PRESS), 2017 22(2022), 6, Seite 946-950 (DE-627)1680946854 16725123 nnns volume:22 year:2022 number:6 pages:946-950 https://doi.org/10.3980/j.issn.1672-5123.2022.6.12 kostenfrei https://doaj.org/article/055a005bee334041b65dbd3d4c843534 kostenfrei http://ies.ijo.cn/cn_publish/2022/6/202206012.pdf kostenfrei https://doaj.org/toc/1672-5123 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_2817 AR 22 2022 6 946-950 |
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Specific pro-resolving mediators(SPM)are a class of lipid mediators that trigger and orchestrate the resolution of inflammation, which formed in cells by the metabolism of polyunsaturated fatty acids. SPM pathway and receptors are highly expressed inocular surface, and constitute endogenous SPM networks which are important for maintaining ocular surface health and immune homeostasis. Recent evidence indicates that SPM and their analogs are essential mediators in promoting corneal wound healing, corneal nerve regeneration, and inhibiting the immune inflammatory response of corneal transplant rejection, allergic conjunctivitis and microbial keratitis. In addition, they are potential therapeutic drug targets of dry eye disease, and provide novel insight on the research and treatment of ocular surface diseases. Here, we will review and discuss evidence for SPM as important endogenous regulators of ocular surface health and disease and their therapeutic potential. |
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Specific pro-resolving mediators(SPM)are a class of lipid mediators that trigger and orchestrate the resolution of inflammation, which formed in cells by the metabolism of polyunsaturated fatty acids. SPM pathway and receptors are highly expressed inocular surface, and constitute endogenous SPM networks which are important for maintaining ocular surface health and immune homeostasis. Recent evidence indicates that SPM and their analogs are essential mediators in promoting corneal wound healing, corneal nerve regeneration, and inhibiting the immune inflammatory response of corneal transplant rejection, allergic conjunctivitis and microbial keratitis. In addition, they are potential therapeutic drug targets of dry eye disease, and provide novel insight on the research and treatment of ocular surface diseases. Here, we will review and discuss evidence for SPM as important endogenous regulators of ocular surface health and disease and their therapeutic potential. |
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Specific pro-resolving mediators(SPM)are a class of lipid mediators that trigger and orchestrate the resolution of inflammation, which formed in cells by the metabolism of polyunsaturated fatty acids. SPM pathway and receptors are highly expressed inocular surface, and constitute endogenous SPM networks which are important for maintaining ocular surface health and immune homeostasis. Recent evidence indicates that SPM and their analogs are essential mediators in promoting corneal wound healing, corneal nerve regeneration, and inhibiting the immune inflammatory response of corneal transplant rejection, allergic conjunctivitis and microbial keratitis. In addition, they are potential therapeutic drug targets of dry eye disease, and provide novel insight on the research and treatment of ocular surface diseases. Here, we will review and discuss evidence for SPM as important endogenous regulators of ocular surface health and disease and their therapeutic potential. |
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| up_date |
2024-07-03T17:38:25.318Z |
| _version_ |
1803580400279224320 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ043451985</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230308072156.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230227s2022 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.3980/j.issn.1672-5123.2022.6.12</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ043451985</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ055a005bee334041b65dbd3d4c843534</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RE1-994</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Li-Xian He</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Research progress of specific pro-resolving mediators in ocular surface diseases</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2022</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Specific pro-resolving mediators(SPM)are a class of lipid mediators that trigger and orchestrate the resolution of inflammation, which formed in cells by the metabolism of polyunsaturated fatty acids. SPM pathway and receptors are highly expressed inocular surface, and constitute endogenous SPM networks which are important for maintaining ocular surface health and immune homeostasis. Recent evidence indicates that SPM and their analogs are essential mediators in promoting corneal wound healing, corneal nerve regeneration, and inhibiting the immune inflammatory response of corneal transplant rejection, allergic conjunctivitis and microbial keratitis. In addition, they are potential therapeutic drug targets of dry eye disease, and provide novel insight on the research and treatment of ocular surface diseases. 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7.4003057 |