Treatment of a cat with presumed Bartonella henselae‐associated immune‐mediated hemolytic anemia, fever, and lymphadenitis

Abstract A 2.5‐year‐old castrated male cat presented with fever and marked generalized lymphadenopathy of 4‐months duration, despite treatment with amoxicillin‐clavulanate/marbofloxacin. Abnormalities were not detected on complete blood count, serum chemistry, and FIV/FeLV test apart from a borderli...
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Autor*in:	Ran Nivy [verfasserIn] Yael Lavi‐Ginzberg [verfasserIn] Keyla Carstens Marques deSousa [verfasserIn] Yael Golani [verfasserIn] Sharon Kuzi [verfasserIn] Yaarit Nachum‐Biala [verfasserIn] Shimon Harrus [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022

Schlagwörter:	bartonellosis feline fever lymphadenitis lymphadenomegaly pradofloxacin

Übergeordnetes Werk:	In: Journal of Veterinary Internal Medicine - Wiley, 2015, 36(2022), 3, Seite 1106-1112
Übergeordnetes Werk:	volume:36 ; year:2022 ; number:3 ; pages:1106-1112

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.1111/jvim.16415

Katalog-ID:	DOAJ043549217

Internformat


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245	1	0	\|a Treatment of a cat with presumed Bartonella henselae‐associated immune‐mediated hemolytic anemia, fever, and lymphadenitis
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520			\|a Abstract A 2.5‐year‐old castrated male cat presented with fever and marked generalized lymphadenopathy of 4‐months duration, despite treatment with amoxicillin‐clavulanate/marbofloxacin. Abnormalities were not detected on complete blood count, serum chemistry, and FIV/FeLV test apart from a borderline, non‐regenerative anemia. Peripheral lymph node fine needle aspirations revealed a marked increase in the percentage of intermediate‐ and lymphoblastic‐lymphocytes in addition to reactive macrophages. Three weeks after presentation, the cat developed a severe, regenerative, immune‐mediated hemolytic anemia (IMHA) which responded to immunosuppressive therapy. Fever and lymphadenopathy persisted. Peripheral lymph nodes tested positive for Bartonella henselae DNA in real‐time PCR assay and sequencing. Treatment with pradofloxacin and doxycycline resulted in resolution of clinical signs, and negative PCR tests. Despite its reported low pathogenicity, B. henselae infection should also be considered in cats with protracted unexplained fever, lymphadenitis, and IMHA. Furthermore, a combination of pradofloxacin and doxycycline might be considered in cats with bartonellosis given its apparent clinical efficacy.
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700	0		\|a Yaarit Nachum‐Biala \|e verfasserin \|4 aut
700	0		\|a Shimon Harrus \|e verfasserin \|4 aut
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allfields	10.1111/jvim.16415 doi (DE-627)DOAJ043549217 (DE-599)DOAJ961d49e588ce4d03a0acff556985f54d DE-627 ger DE-627 rakwb eng SF600-1100 Ran Nivy verfasserin aut Treatment of a cat with presumed Bartonella henselae‐associated immune‐mediated hemolytic anemia, fever, and lymphadenitis 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract A 2.5‐year‐old castrated male cat presented with fever and marked generalized lymphadenopathy of 4‐months duration, despite treatment with amoxicillin‐clavulanate/marbofloxacin. Abnormalities were not detected on complete blood count, serum chemistry, and FIV/FeLV test apart from a borderline, non‐regenerative anemia. Peripheral lymph node fine needle aspirations revealed a marked increase in the percentage of intermediate‐ and lymphoblastic‐lymphocytes in addition to reactive macrophages. Three weeks after presentation, the cat developed a severe, regenerative, immune‐mediated hemolytic anemia (IMHA) which responded to immunosuppressive therapy. Fever and lymphadenopathy persisted. Peripheral lymph nodes tested positive for Bartonella henselae DNA in real‐time PCR assay and sequencing. Treatment with pradofloxacin and doxycycline resulted in resolution of clinical signs, and negative PCR tests. Despite its reported low pathogenicity, B. henselae infection should also be considered in cats with protracted unexplained fever, lymphadenitis, and IMHA. Furthermore, a combination of pradofloxacin and doxycycline might be considered in cats with bartonellosis given its apparent clinical efficacy. bartonellosis feline fever lymphadenitis lymphadenomegaly pradofloxacin Veterinary medicine Yael Lavi‐Ginzberg verfasserin aut Keyla Carstens Marques deSousa verfasserin aut Yael Golani verfasserin aut Sharon Kuzi verfasserin aut Yaarit Nachum‐Biala verfasserin aut Shimon Harrus verfasserin aut In Journal of Veterinary Internal Medicine Wiley, 2015 36(2022), 3, Seite 1106-1112 (DE-627)479856192 (DE-600)2177690-8 19391676 nnns volume:36 year:2022 number:3 pages:1106-1112 https://doi.org/10.1111/jvim.16415 kostenfrei https://doaj.org/article/961d49e588ce4d03a0acff556985f54d kostenfrei https://doi.org/10.1111/jvim.16415 kostenfrei https://doaj.org/toc/0891-6640 Journal toc kostenfrei https://doaj.org/toc/1939-1676 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_171 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 36 2022 3 1106-1112
spelling	10.1111/jvim.16415 doi (DE-627)DOAJ043549217 (DE-599)DOAJ961d49e588ce4d03a0acff556985f54d DE-627 ger DE-627 rakwb eng SF600-1100 Ran Nivy verfasserin aut Treatment of a cat with presumed Bartonella henselae‐associated immune‐mediated hemolytic anemia, fever, and lymphadenitis 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract A 2.5‐year‐old castrated male cat presented with fever and marked generalized lymphadenopathy of 4‐months duration, despite treatment with amoxicillin‐clavulanate/marbofloxacin. Abnormalities were not detected on complete blood count, serum chemistry, and FIV/FeLV test apart from a borderline, non‐regenerative anemia. Peripheral lymph node fine needle aspirations revealed a marked increase in the percentage of intermediate‐ and lymphoblastic‐lymphocytes in addition to reactive macrophages. Three weeks after presentation, the cat developed a severe, regenerative, immune‐mediated hemolytic anemia (IMHA) which responded to immunosuppressive therapy. Fever and lymphadenopathy persisted. Peripheral lymph nodes tested positive for Bartonella henselae DNA in real‐time PCR assay and sequencing. Treatment with pradofloxacin and doxycycline resulted in resolution of clinical signs, and negative PCR tests. Despite its reported low pathogenicity, B. henselae infection should also be considered in cats with protracted unexplained fever, lymphadenitis, and IMHA. Furthermore, a combination of pradofloxacin and doxycycline might be considered in cats with bartonellosis given its apparent clinical efficacy. bartonellosis feline fever lymphadenitis lymphadenomegaly pradofloxacin Veterinary medicine Yael Lavi‐Ginzberg verfasserin aut Keyla Carstens Marques deSousa verfasserin aut Yael Golani verfasserin aut Sharon Kuzi verfasserin aut Yaarit Nachum‐Biala verfasserin aut Shimon Harrus verfasserin aut In Journal of Veterinary Internal Medicine Wiley, 2015 36(2022), 3, Seite 1106-1112 (DE-627)479856192 (DE-600)2177690-8 19391676 nnns volume:36 year:2022 number:3 pages:1106-1112 https://doi.org/10.1111/jvim.16415 kostenfrei https://doaj.org/article/961d49e588ce4d03a0acff556985f54d kostenfrei https://doi.org/10.1111/jvim.16415 kostenfrei https://doaj.org/toc/0891-6640 Journal toc kostenfrei https://doaj.org/toc/1939-1676 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_171 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 36 2022 3 1106-1112
allfields_unstemmed	10.1111/jvim.16415 doi (DE-627)DOAJ043549217 (DE-599)DOAJ961d49e588ce4d03a0acff556985f54d DE-627 ger DE-627 rakwb eng SF600-1100 Ran Nivy verfasserin aut Treatment of a cat with presumed Bartonella henselae‐associated immune‐mediated hemolytic anemia, fever, and lymphadenitis 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract A 2.5‐year‐old castrated male cat presented with fever and marked generalized lymphadenopathy of 4‐months duration, despite treatment with amoxicillin‐clavulanate/marbofloxacin. Abnormalities were not detected on complete blood count, serum chemistry, and FIV/FeLV test apart from a borderline, non‐regenerative anemia. Peripheral lymph node fine needle aspirations revealed a marked increase in the percentage of intermediate‐ and lymphoblastic‐lymphocytes in addition to reactive macrophages. Three weeks after presentation, the cat developed a severe, regenerative, immune‐mediated hemolytic anemia (IMHA) which responded to immunosuppressive therapy. Fever and lymphadenopathy persisted. Peripheral lymph nodes tested positive for Bartonella henselae DNA in real‐time PCR assay and sequencing. Treatment with pradofloxacin and doxycycline resulted in resolution of clinical signs, and negative PCR tests. Despite its reported low pathogenicity, B. henselae infection should also be considered in cats with protracted unexplained fever, lymphadenitis, and IMHA. Furthermore, a combination of pradofloxacin and doxycycline might be considered in cats with bartonellosis given its apparent clinical efficacy. bartonellosis feline fever lymphadenitis lymphadenomegaly pradofloxacin Veterinary medicine Yael Lavi‐Ginzberg verfasserin aut Keyla Carstens Marques deSousa verfasserin aut Yael Golani verfasserin aut Sharon Kuzi verfasserin aut Yaarit Nachum‐Biala verfasserin aut Shimon Harrus verfasserin aut In Journal of Veterinary Internal Medicine Wiley, 2015 36(2022), 3, Seite 1106-1112 (DE-627)479856192 (DE-600)2177690-8 19391676 nnns volume:36 year:2022 number:3 pages:1106-1112 https://doi.org/10.1111/jvim.16415 kostenfrei https://doaj.org/article/961d49e588ce4d03a0acff556985f54d kostenfrei https://doi.org/10.1111/jvim.16415 kostenfrei https://doaj.org/toc/0891-6640 Journal toc kostenfrei https://doaj.org/toc/1939-1676 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_171 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 36 2022 3 1106-1112
allfieldsGer	10.1111/jvim.16415 doi (DE-627)DOAJ043549217 (DE-599)DOAJ961d49e588ce4d03a0acff556985f54d DE-627 ger DE-627 rakwb eng SF600-1100 Ran Nivy verfasserin aut Treatment of a cat with presumed Bartonella henselae‐associated immune‐mediated hemolytic anemia, fever, and lymphadenitis 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract A 2.5‐year‐old castrated male cat presented with fever and marked generalized lymphadenopathy of 4‐months duration, despite treatment with amoxicillin‐clavulanate/marbofloxacin. Abnormalities were not detected on complete blood count, serum chemistry, and FIV/FeLV test apart from a borderline, non‐regenerative anemia. Peripheral lymph node fine needle aspirations revealed a marked increase in the percentage of intermediate‐ and lymphoblastic‐lymphocytes in addition to reactive macrophages. Three weeks after presentation, the cat developed a severe, regenerative, immune‐mediated hemolytic anemia (IMHA) which responded to immunosuppressive therapy. Fever and lymphadenopathy persisted. Peripheral lymph nodes tested positive for Bartonella henselae DNA in real‐time PCR assay and sequencing. Treatment with pradofloxacin and doxycycline resulted in resolution of clinical signs, and negative PCR tests. Despite its reported low pathogenicity, B. henselae infection should also be considered in cats with protracted unexplained fever, lymphadenitis, and IMHA. Furthermore, a combination of pradofloxacin and doxycycline might be considered in cats with bartonellosis given its apparent clinical efficacy. bartonellosis feline fever lymphadenitis lymphadenomegaly pradofloxacin Veterinary medicine Yael Lavi‐Ginzberg verfasserin aut Keyla Carstens Marques deSousa verfasserin aut Yael Golani verfasserin aut Sharon Kuzi verfasserin aut Yaarit Nachum‐Biala verfasserin aut Shimon Harrus verfasserin aut In Journal of Veterinary Internal Medicine Wiley, 2015 36(2022), 3, Seite 1106-1112 (DE-627)479856192 (DE-600)2177690-8 19391676 nnns volume:36 year:2022 number:3 pages:1106-1112 https://doi.org/10.1111/jvim.16415 kostenfrei https://doaj.org/article/961d49e588ce4d03a0acff556985f54d kostenfrei https://doi.org/10.1111/jvim.16415 kostenfrei https://doaj.org/toc/0891-6640 Journal toc kostenfrei https://doaj.org/toc/1939-1676 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_171 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 36 2022 3 1106-1112
allfieldsSound	10.1111/jvim.16415 doi (DE-627)DOAJ043549217 (DE-599)DOAJ961d49e588ce4d03a0acff556985f54d DE-627 ger DE-627 rakwb eng SF600-1100 Ran Nivy verfasserin aut Treatment of a cat with presumed Bartonella henselae‐associated immune‐mediated hemolytic anemia, fever, and lymphadenitis 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract A 2.5‐year‐old castrated male cat presented with fever and marked generalized lymphadenopathy of 4‐months duration, despite treatment with amoxicillin‐clavulanate/marbofloxacin. Abnormalities were not detected on complete blood count, serum chemistry, and FIV/FeLV test apart from a borderline, non‐regenerative anemia. Peripheral lymph node fine needle aspirations revealed a marked increase in the percentage of intermediate‐ and lymphoblastic‐lymphocytes in addition to reactive macrophages. Three weeks after presentation, the cat developed a severe, regenerative, immune‐mediated hemolytic anemia (IMHA) which responded to immunosuppressive therapy. Fever and lymphadenopathy persisted. Peripheral lymph nodes tested positive for Bartonella henselae DNA in real‐time PCR assay and sequencing. Treatment with pradofloxacin and doxycycline resulted in resolution of clinical signs, and negative PCR tests. Despite its reported low pathogenicity, B. henselae infection should also be considered in cats with protracted unexplained fever, lymphadenitis, and IMHA. Furthermore, a combination of pradofloxacin and doxycycline might be considered in cats with bartonellosis given its apparent clinical efficacy. bartonellosis feline fever lymphadenitis lymphadenomegaly pradofloxacin Veterinary medicine Yael Lavi‐Ginzberg verfasserin aut Keyla Carstens Marques deSousa verfasserin aut Yael Golani verfasserin aut Sharon Kuzi verfasserin aut Yaarit Nachum‐Biala verfasserin aut Shimon Harrus verfasserin aut In Journal of Veterinary Internal Medicine Wiley, 2015 36(2022), 3, Seite 1106-1112 (DE-627)479856192 (DE-600)2177690-8 19391676 nnns volume:36 year:2022 number:3 pages:1106-1112 https://doi.org/10.1111/jvim.16415 kostenfrei https://doaj.org/article/961d49e588ce4d03a0acff556985f54d kostenfrei https://doi.org/10.1111/jvim.16415 kostenfrei https://doaj.org/toc/0891-6640 Journal toc kostenfrei https://doaj.org/toc/1939-1676 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_171 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_636 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2026 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2037 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2108 GBV_ILN_2110 GBV_ILN_2111 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2144 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4046 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4336 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 36 2022 3 1106-1112
language	English
source	In Journal of Veterinary Internal Medicine 36(2022), 3, Seite 1106-1112 volume:36 year:2022 number:3 pages:1106-1112
sourceStr	In Journal of Veterinary Internal Medicine 36(2022), 3, Seite 1106-1112 volume:36 year:2022 number:3 pages:1106-1112
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	bartonellosis feline fever lymphadenitis lymphadenomegaly pradofloxacin Veterinary medicine
isfreeaccess_bool	true
container_title	Journal of Veterinary Internal Medicine
authorswithroles_txt_mv	Ran Nivy @@aut@@ Yael Lavi‐Ginzberg @@aut@@ Keyla Carstens Marques deSousa @@aut@@ Yael Golani @@aut@@ Sharon Kuzi @@aut@@ Yaarit Nachum‐Biala @@aut@@ Shimon Harrus @@aut@@
publishDateDaySort_date	2022-01-01T00:00:00Z
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id	DOAJ043549217
language_de	englisch
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callnumber-first	S - Agriculture
author	Ran Nivy
spellingShingle	Ran Nivy misc SF600-1100 misc bartonellosis misc feline misc fever misc lymphadenitis misc lymphadenomegaly misc pradofloxacin misc Veterinary medicine Treatment of a cat with presumed Bartonella henselae‐associated immune‐mediated hemolytic anemia, fever, and lymphadenitis
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topic_title	SF600-1100 Treatment of a cat with presumed Bartonella henselae‐associated immune‐mediated hemolytic anemia, fever, and lymphadenitis bartonellosis feline fever lymphadenitis lymphadenomegaly pradofloxacin
topic	misc SF600-1100 misc bartonellosis misc feline misc fever misc lymphadenitis misc lymphadenomegaly misc pradofloxacin misc Veterinary medicine
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title	Treatment of a cat with presumed Bartonella henselae‐associated immune‐mediated hemolytic anemia, fever, and lymphadenitis
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title_full	Treatment of a cat with presumed Bartonella henselae‐associated immune‐mediated hemolytic anemia, fever, and lymphadenitis
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title_sort	treatment of a cat with presumed bartonella henselae‐associated immune‐mediated hemolytic anemia, fever, and lymphadenitis
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title_auth	Treatment of a cat with presumed Bartonella henselae‐associated immune‐mediated hemolytic anemia, fever, and lymphadenitis
abstract	Abstract A 2.5‐year‐old castrated male cat presented with fever and marked generalized lymphadenopathy of 4‐months duration, despite treatment with amoxicillin‐clavulanate/marbofloxacin. Abnormalities were not detected on complete blood count, serum chemistry, and FIV/FeLV test apart from a borderline, non‐regenerative anemia. Peripheral lymph node fine needle aspirations revealed a marked increase in the percentage of intermediate‐ and lymphoblastic‐lymphocytes in addition to reactive macrophages. Three weeks after presentation, the cat developed a severe, regenerative, immune‐mediated hemolytic anemia (IMHA) which responded to immunosuppressive therapy. Fever and lymphadenopathy persisted. Peripheral lymph nodes tested positive for Bartonella henselae DNA in real‐time PCR assay and sequencing. Treatment with pradofloxacin and doxycycline resulted in resolution of clinical signs, and negative PCR tests. Despite its reported low pathogenicity, B. henselae infection should also be considered in cats with protracted unexplained fever, lymphadenitis, and IMHA. Furthermore, a combination of pradofloxacin and doxycycline might be considered in cats with bartonellosis given its apparent clinical efficacy.
abstractGer	Abstract A 2.5‐year‐old castrated male cat presented with fever and marked generalized lymphadenopathy of 4‐months duration, despite treatment with amoxicillin‐clavulanate/marbofloxacin. Abnormalities were not detected on complete blood count, serum chemistry, and FIV/FeLV test apart from a borderline, non‐regenerative anemia. Peripheral lymph node fine needle aspirations revealed a marked increase in the percentage of intermediate‐ and lymphoblastic‐lymphocytes in addition to reactive macrophages. Three weeks after presentation, the cat developed a severe, regenerative, immune‐mediated hemolytic anemia (IMHA) which responded to immunosuppressive therapy. Fever and lymphadenopathy persisted. Peripheral lymph nodes tested positive for Bartonella henselae DNA in real‐time PCR assay and sequencing. Treatment with pradofloxacin and doxycycline resulted in resolution of clinical signs, and negative PCR tests. Despite its reported low pathogenicity, B. henselae infection should also be considered in cats with protracted unexplained fever, lymphadenitis, and IMHA. Furthermore, a combination of pradofloxacin and doxycycline might be considered in cats with bartonellosis given its apparent clinical efficacy.
abstract_unstemmed	Abstract A 2.5‐year‐old castrated male cat presented with fever and marked generalized lymphadenopathy of 4‐months duration, despite treatment with amoxicillin‐clavulanate/marbofloxacin. Abnormalities were not detected on complete blood count, serum chemistry, and FIV/FeLV test apart from a borderline, non‐regenerative anemia. Peripheral lymph node fine needle aspirations revealed a marked increase in the percentage of intermediate‐ and lymphoblastic‐lymphocytes in addition to reactive macrophages. Three weeks after presentation, the cat developed a severe, regenerative, immune‐mediated hemolytic anemia (IMHA) which responded to immunosuppressive therapy. Fever and lymphadenopathy persisted. Peripheral lymph nodes tested positive for Bartonella henselae DNA in real‐time PCR assay and sequencing. Treatment with pradofloxacin and doxycycline resulted in resolution of clinical signs, and negative PCR tests. Despite its reported low pathogenicity, B. henselae infection should also be considered in cats with protracted unexplained fever, lymphadenitis, and IMHA. Furthermore, a combination of pradofloxacin and doxycycline might be considered in cats with bartonellosis given its apparent clinical efficacy.
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title_short	Treatment of a cat with presumed Bartonella henselae‐associated immune‐mediated hemolytic anemia, fever, and lymphadenitis
url	https://doi.org/10.1111/jvim.16415 https://doaj.org/article/961d49e588ce4d03a0acff556985f54d https://doaj.org/toc/0891-6640 https://doaj.org/toc/1939-1676
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Treatment of a cat with presumed Bartonella henselae‐associated immune‐mediated hemolytic anemia, fever, and lymphadenitis

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