Assessment of the correlation between various risk factors and orofacial cleft disorder spectrum: a retrospective case-control study

Abstract Background Orofacial clefts (OFCs) comprise a wide range of malformations, including cleft lip, cleft palate, and cleft lip with cleft palate, which can vary in terms of etiology, severity, and disease burden. Objective(s) This study aimed to evaluate the correlation between various risk fa...
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Autor*in:	Behzad Cheshmi [verfasserIn] Zahra Jafari [verfasserIn] Mohammad Ali Naseri [verfasserIn] Heidar Ali Davari [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2020

Schlagwörter:	Cleft lip Cleft palate Orofacial cleft Miscarriage Abortion Pregnancy

Übergeordnetes Werk:	In: Maxillofacial Plastic and Reconstructive Surgery - SpringerOpen, 2016, 42(2020), 1, Seite 6
Übergeordnetes Werk:	volume:42 ; year:2020 ; number:1 ; pages:6

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1186/s40902-020-00270-7

Katalog-ID:	DOAJ043643795

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520			\|a Abstract Background Orofacial clefts (OFCs) comprise a wide range of malformations, including cleft lip, cleft palate, and cleft lip with cleft palate, which can vary in terms of etiology, severity, and disease burden. Objective(s) This study aimed to evaluate the correlation between various risk factors and orofacial cleft disorder spectrum in newborns. Study design A total of 323 cases and 400 controls were enrolled in this study and evaluated in terms of the maternal history of abortion or miscarriage, child’s sex, maternal and paternal age, maternal history of systemic disease, history of medication therapy during pregnancy, birth order, consanguineous marriage, and complications during pregnancy. Results Analysis of the results suggested that consanguineous marriage, a maternal history of abortion/miscarriage, and complications during pregnancy could potentially increase the risk of OFCs in children (P < 0.05). However, the analyses revealed that the other variables could not potentially increase the risk of OFCs (P < 0.05). Conclusion(s) Multiple cofactors may simultaneously contribute to the formation of such abnormalities; therefore, a comprehensive, multidisciplinary care program is necessary to ensure a successful pregnancy period and the birth of a healthy newborn.
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allfields	10.1186/s40902-020-00270-7 doi (DE-627)DOAJ043643795 (DE-599)DOAJ69d354e44bd6471bb1f3031aad767a9a DE-627 ger DE-627 rakwb eng RK1-715 RD1-811 Behzad Cheshmi verfasserin aut Assessment of the correlation between various risk factors and orofacial cleft disorder spectrum: a retrospective case-control study 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Orofacial clefts (OFCs) comprise a wide range of malformations, including cleft lip, cleft palate, and cleft lip with cleft palate, which can vary in terms of etiology, severity, and disease burden. Objective(s) This study aimed to evaluate the correlation between various risk factors and orofacial cleft disorder spectrum in newborns. Study design A total of 323 cases and 400 controls were enrolled in this study and evaluated in terms of the maternal history of abortion or miscarriage, child’s sex, maternal and paternal age, maternal history of systemic disease, history of medication therapy during pregnancy, birth order, consanguineous marriage, and complications during pregnancy. Results Analysis of the results suggested that consanguineous marriage, a maternal history of abortion/miscarriage, and complications during pregnancy could potentially increase the risk of OFCs in children (P < 0.05). However, the analyses revealed that the other variables could not potentially increase the risk of OFCs (P < 0.05). Conclusion(s) Multiple cofactors may simultaneously contribute to the formation of such abnormalities; therefore, a comprehensive, multidisciplinary care program is necessary to ensure a successful pregnancy period and the birth of a healthy newborn. Cleft lip Cleft palate Orofacial cleft Miscarriage Abortion Pregnancy Dentistry Surgery Zahra Jafari verfasserin aut Mohammad Ali Naseri verfasserin aut Heidar Ali Davari verfasserin aut In Maxillofacial Plastic and Reconstructive Surgery SpringerOpen, 2016 42(2020), 1, Seite 6 (DE-627)821519573 (DE-600)2815852-0 22888586 nnns volume:42 year:2020 number:1 pages:6 https://doi.org/10.1186/s40902-020-00270-7 kostenfrei https://doaj.org/article/69d354e44bd6471bb1f3031aad767a9a kostenfrei http://link.springer.com/article/10.1186/s40902-020-00270-7 kostenfrei https://doaj.org/toc/2288-8586 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 42 2020 1 6
spelling	10.1186/s40902-020-00270-7 doi (DE-627)DOAJ043643795 (DE-599)DOAJ69d354e44bd6471bb1f3031aad767a9a DE-627 ger DE-627 rakwb eng RK1-715 RD1-811 Behzad Cheshmi verfasserin aut Assessment of the correlation between various risk factors and orofacial cleft disorder spectrum: a retrospective case-control study 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Orofacial clefts (OFCs) comprise a wide range of malformations, including cleft lip, cleft palate, and cleft lip with cleft palate, which can vary in terms of etiology, severity, and disease burden. Objective(s) This study aimed to evaluate the correlation between various risk factors and orofacial cleft disorder spectrum in newborns. Study design A total of 323 cases and 400 controls were enrolled in this study and evaluated in terms of the maternal history of abortion or miscarriage, child’s sex, maternal and paternal age, maternal history of systemic disease, history of medication therapy during pregnancy, birth order, consanguineous marriage, and complications during pregnancy. Results Analysis of the results suggested that consanguineous marriage, a maternal history of abortion/miscarriage, and complications during pregnancy could potentially increase the risk of OFCs in children (P < 0.05). However, the analyses revealed that the other variables could not potentially increase the risk of OFCs (P < 0.05). Conclusion(s) Multiple cofactors may simultaneously contribute to the formation of such abnormalities; therefore, a comprehensive, multidisciplinary care program is necessary to ensure a successful pregnancy period and the birth of a healthy newborn. Cleft lip Cleft palate Orofacial cleft Miscarriage Abortion Pregnancy Dentistry Surgery Zahra Jafari verfasserin aut Mohammad Ali Naseri verfasserin aut Heidar Ali Davari verfasserin aut In Maxillofacial Plastic and Reconstructive Surgery SpringerOpen, 2016 42(2020), 1, Seite 6 (DE-627)821519573 (DE-600)2815852-0 22888586 nnns volume:42 year:2020 number:1 pages:6 https://doi.org/10.1186/s40902-020-00270-7 kostenfrei https://doaj.org/article/69d354e44bd6471bb1f3031aad767a9a kostenfrei http://link.springer.com/article/10.1186/s40902-020-00270-7 kostenfrei https://doaj.org/toc/2288-8586 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 42 2020 1 6
allfields_unstemmed	10.1186/s40902-020-00270-7 doi (DE-627)DOAJ043643795 (DE-599)DOAJ69d354e44bd6471bb1f3031aad767a9a DE-627 ger DE-627 rakwb eng RK1-715 RD1-811 Behzad Cheshmi verfasserin aut Assessment of the correlation between various risk factors and orofacial cleft disorder spectrum: a retrospective case-control study 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Orofacial clefts (OFCs) comprise a wide range of malformations, including cleft lip, cleft palate, and cleft lip with cleft palate, which can vary in terms of etiology, severity, and disease burden. Objective(s) This study aimed to evaluate the correlation between various risk factors and orofacial cleft disorder spectrum in newborns. Study design A total of 323 cases and 400 controls were enrolled in this study and evaluated in terms of the maternal history of abortion or miscarriage, child’s sex, maternal and paternal age, maternal history of systemic disease, history of medication therapy during pregnancy, birth order, consanguineous marriage, and complications during pregnancy. Results Analysis of the results suggested that consanguineous marriage, a maternal history of abortion/miscarriage, and complications during pregnancy could potentially increase the risk of OFCs in children (P < 0.05). However, the analyses revealed that the other variables could not potentially increase the risk of OFCs (P < 0.05). Conclusion(s) Multiple cofactors may simultaneously contribute to the formation of such abnormalities; therefore, a comprehensive, multidisciplinary care program is necessary to ensure a successful pregnancy period and the birth of a healthy newborn. Cleft lip Cleft palate Orofacial cleft Miscarriage Abortion Pregnancy Dentistry Surgery Zahra Jafari verfasserin aut Mohammad Ali Naseri verfasserin aut Heidar Ali Davari verfasserin aut In Maxillofacial Plastic and Reconstructive Surgery SpringerOpen, 2016 42(2020), 1, Seite 6 (DE-627)821519573 (DE-600)2815852-0 22888586 nnns volume:42 year:2020 number:1 pages:6 https://doi.org/10.1186/s40902-020-00270-7 kostenfrei https://doaj.org/article/69d354e44bd6471bb1f3031aad767a9a kostenfrei http://link.springer.com/article/10.1186/s40902-020-00270-7 kostenfrei https://doaj.org/toc/2288-8586 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 42 2020 1 6
allfieldsGer	10.1186/s40902-020-00270-7 doi (DE-627)DOAJ043643795 (DE-599)DOAJ69d354e44bd6471bb1f3031aad767a9a DE-627 ger DE-627 rakwb eng RK1-715 RD1-811 Behzad Cheshmi verfasserin aut Assessment of the correlation between various risk factors and orofacial cleft disorder spectrum: a retrospective case-control study 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Orofacial clefts (OFCs) comprise a wide range of malformations, including cleft lip, cleft palate, and cleft lip with cleft palate, which can vary in terms of etiology, severity, and disease burden. Objective(s) This study aimed to evaluate the correlation between various risk factors and orofacial cleft disorder spectrum in newborns. Study design A total of 323 cases and 400 controls were enrolled in this study and evaluated in terms of the maternal history of abortion or miscarriage, child’s sex, maternal and paternal age, maternal history of systemic disease, history of medication therapy during pregnancy, birth order, consanguineous marriage, and complications during pregnancy. Results Analysis of the results suggested that consanguineous marriage, a maternal history of abortion/miscarriage, and complications during pregnancy could potentially increase the risk of OFCs in children (P < 0.05). However, the analyses revealed that the other variables could not potentially increase the risk of OFCs (P < 0.05). Conclusion(s) Multiple cofactors may simultaneously contribute to the formation of such abnormalities; therefore, a comprehensive, multidisciplinary care program is necessary to ensure a successful pregnancy period and the birth of a healthy newborn. Cleft lip Cleft palate Orofacial cleft Miscarriage Abortion Pregnancy Dentistry Surgery Zahra Jafari verfasserin aut Mohammad Ali Naseri verfasserin aut Heidar Ali Davari verfasserin aut In Maxillofacial Plastic and Reconstructive Surgery SpringerOpen, 2016 42(2020), 1, Seite 6 (DE-627)821519573 (DE-600)2815852-0 22888586 nnns volume:42 year:2020 number:1 pages:6 https://doi.org/10.1186/s40902-020-00270-7 kostenfrei https://doaj.org/article/69d354e44bd6471bb1f3031aad767a9a kostenfrei http://link.springer.com/article/10.1186/s40902-020-00270-7 kostenfrei https://doaj.org/toc/2288-8586 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 42 2020 1 6
allfieldsSound	10.1186/s40902-020-00270-7 doi (DE-627)DOAJ043643795 (DE-599)DOAJ69d354e44bd6471bb1f3031aad767a9a DE-627 ger DE-627 rakwb eng RK1-715 RD1-811 Behzad Cheshmi verfasserin aut Assessment of the correlation between various risk factors and orofacial cleft disorder spectrum: a retrospective case-control study 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Orofacial clefts (OFCs) comprise a wide range of malformations, including cleft lip, cleft palate, and cleft lip with cleft palate, which can vary in terms of etiology, severity, and disease burden. Objective(s) This study aimed to evaluate the correlation between various risk factors and orofacial cleft disorder spectrum in newborns. Study design A total of 323 cases and 400 controls were enrolled in this study and evaluated in terms of the maternal history of abortion or miscarriage, child’s sex, maternal and paternal age, maternal history of systemic disease, history of medication therapy during pregnancy, birth order, consanguineous marriage, and complications during pregnancy. Results Analysis of the results suggested that consanguineous marriage, a maternal history of abortion/miscarriage, and complications during pregnancy could potentially increase the risk of OFCs in children (P < 0.05). However, the analyses revealed that the other variables could not potentially increase the risk of OFCs (P < 0.05). Conclusion(s) Multiple cofactors may simultaneously contribute to the formation of such abnormalities; therefore, a comprehensive, multidisciplinary care program is necessary to ensure a successful pregnancy period and the birth of a healthy newborn. Cleft lip Cleft palate Orofacial cleft Miscarriage Abortion Pregnancy Dentistry Surgery Zahra Jafari verfasserin aut Mohammad Ali Naseri verfasserin aut Heidar Ali Davari verfasserin aut In Maxillofacial Plastic and Reconstructive Surgery SpringerOpen, 2016 42(2020), 1, Seite 6 (DE-627)821519573 (DE-600)2815852-0 22888586 nnns volume:42 year:2020 number:1 pages:6 https://doi.org/10.1186/s40902-020-00270-7 kostenfrei https://doaj.org/article/69d354e44bd6471bb1f3031aad767a9a kostenfrei http://link.springer.com/article/10.1186/s40902-020-00270-7 kostenfrei https://doaj.org/toc/2288-8586 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 42 2020 1 6
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Objective(s) This study aimed to evaluate the correlation between various risk factors and orofacial cleft disorder spectrum in newborns. Study design A total of 323 cases and 400 controls were enrolled in this study and evaluated in terms of the maternal history of abortion or miscarriage, child’s sex, maternal and paternal age, maternal history of systemic disease, history of medication therapy during pregnancy, birth order, consanguineous marriage, and complications during pregnancy. Results Analysis of the results suggested that consanguineous marriage, a maternal history of abortion/miscarriage, and complications during pregnancy could potentially increase the risk of OFCs in children (P < 0.05). However, the analyses revealed that the other variables could not potentially increase the risk of OFCs (P < 0.05). 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callnumber-first	R - Medicine
author	Behzad Cheshmi
spellingShingle	Behzad Cheshmi misc RK1-715 misc RD1-811 misc Cleft lip misc Cleft palate misc Orofacial cleft misc Miscarriage misc Abortion misc Pregnancy misc Dentistry misc Surgery Assessment of the correlation between various risk factors and orofacial cleft disorder spectrum: a retrospective case-control study
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topic_title	RK1-715 RD1-811 Assessment of the correlation between various risk factors and orofacial cleft disorder spectrum: a retrospective case-control study Cleft lip Cleft palate Orofacial cleft Miscarriage Abortion Pregnancy
topic	misc RK1-715 misc RD1-811 misc Cleft lip misc Cleft palate misc Orofacial cleft misc Miscarriage misc Abortion misc Pregnancy misc Dentistry misc Surgery
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title	Assessment of the correlation between various risk factors and orofacial cleft disorder spectrum: a retrospective case-control study
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title_full	Assessment of the correlation between various risk factors and orofacial cleft disorder spectrum: a retrospective case-control study
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title_sort	assessment of the correlation between various risk factors and orofacial cleft disorder spectrum: a retrospective case-control study
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title_auth	Assessment of the correlation between various risk factors and orofacial cleft disorder spectrum: a retrospective case-control study
abstract	Abstract Background Orofacial clefts (OFCs) comprise a wide range of malformations, including cleft lip, cleft palate, and cleft lip with cleft palate, which can vary in terms of etiology, severity, and disease burden. Objective(s) This study aimed to evaluate the correlation between various risk factors and orofacial cleft disorder spectrum in newborns. Study design A total of 323 cases and 400 controls were enrolled in this study and evaluated in terms of the maternal history of abortion or miscarriage, child’s sex, maternal and paternal age, maternal history of systemic disease, history of medication therapy during pregnancy, birth order, consanguineous marriage, and complications during pregnancy. Results Analysis of the results suggested that consanguineous marriage, a maternal history of abortion/miscarriage, and complications during pregnancy could potentially increase the risk of OFCs in children (P < 0.05). However, the analyses revealed that the other variables could not potentially increase the risk of OFCs (P < 0.05). Conclusion(s) Multiple cofactors may simultaneously contribute to the formation of such abnormalities; therefore, a comprehensive, multidisciplinary care program is necessary to ensure a successful pregnancy period and the birth of a healthy newborn.
abstractGer	Abstract Background Orofacial clefts (OFCs) comprise a wide range of malformations, including cleft lip, cleft palate, and cleft lip with cleft palate, which can vary in terms of etiology, severity, and disease burden. Objective(s) This study aimed to evaluate the correlation between various risk factors and orofacial cleft disorder spectrum in newborns. Study design A total of 323 cases and 400 controls were enrolled in this study and evaluated in terms of the maternal history of abortion or miscarriage, child’s sex, maternal and paternal age, maternal history of systemic disease, history of medication therapy during pregnancy, birth order, consanguineous marriage, and complications during pregnancy. Results Analysis of the results suggested that consanguineous marriage, a maternal history of abortion/miscarriage, and complications during pregnancy could potentially increase the risk of OFCs in children (P < 0.05). However, the analyses revealed that the other variables could not potentially increase the risk of OFCs (P < 0.05). Conclusion(s) Multiple cofactors may simultaneously contribute to the formation of such abnormalities; therefore, a comprehensive, multidisciplinary care program is necessary to ensure a successful pregnancy period and the birth of a healthy newborn.
abstract_unstemmed	Abstract Background Orofacial clefts (OFCs) comprise a wide range of malformations, including cleft lip, cleft palate, and cleft lip with cleft palate, which can vary in terms of etiology, severity, and disease burden. Objective(s) This study aimed to evaluate the correlation between various risk factors and orofacial cleft disorder spectrum in newborns. Study design A total of 323 cases and 400 controls were enrolled in this study and evaluated in terms of the maternal history of abortion or miscarriage, child’s sex, maternal and paternal age, maternal history of systemic disease, history of medication therapy during pregnancy, birth order, consanguineous marriage, and complications during pregnancy. Results Analysis of the results suggested that consanguineous marriage, a maternal history of abortion/miscarriage, and complications during pregnancy could potentially increase the risk of OFCs in children (P < 0.05). However, the analyses revealed that the other variables could not potentially increase the risk of OFCs (P < 0.05). Conclusion(s) Multiple cofactors may simultaneously contribute to the formation of such abnormalities; therefore, a comprehensive, multidisciplinary care program is necessary to ensure a successful pregnancy period and the birth of a healthy newborn.
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title_short	Assessment of the correlation between various risk factors and orofacial cleft disorder spectrum: a retrospective case-control study
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