Serum inflammatory cytokines combined with NIHSS to evaluate the condition of patients with acute ischemic stroke
<strong<Objective</strong< To explore the changes of serum inflammatory cytokines and National Institute of Health Stroke Scale (NIHSS) score in acute ischemic stroke patients and their clinical significances on patients' condition assessment. <strong<Methods</strong< Th...
Ausführliche Beschreibung
Autor*in: |
Heng YU [verfasserIn] Chong-rong LONG [verfasserIn] Liang WANG [verfasserIn] |
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E-Artikel |
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Englisch ; Chinesisch |
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2013 |
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Übergeordnetes Werk: |
In: Chinese Journal of Contemporary Neurology and Neurosurgery - Tianjin Huanhu Hospital, 2013, 13(2013), 9, Seite 801-804 |
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Übergeordnetes Werk: |
volume:13 ; year:2013 ; number:9 ; pages:801-804 |
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DOAJ04402231X |
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520 | |a <strong<Objective</strong< To explore the changes of serum inflammatory cytokines and National Institute of Health Stroke Scale (NIHSS) score in acute ischemic stroke patients and their clinical significances on patients' condition assessment. <strong<Methods</strong< The serum levels of three cytokines, including interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) and high⁃sensitivity C-reactive protein (hs-CRP), were measured and compared between 90 acute ischemic stroke patients (ischemic stroke group) and 50 healthy people (normal control group). The above-mentioned three cytokines and NIHSS scores were compared between before and after treatment in ischemic stroke group. <strong<Results</strong< Patients in ischemic stroke group were divided into three subgroups according to different infarct sizes: large (> 10 cm3), medium (5-10 cm3) and small (< 5 cm3). The serum levels of three cytokines were significantly higher in three subgroups than those in the normal control group before treatment (P < 0.01). Compared with before treatment, both the serum levels of three cytokines and the NIHSS scores in ishemic stroke patients reduced significantly after treatment (P < 0.01, for all). <strong<Conclusion</strong< Serum levels of inflammatory cytokines and NIHSS scores in patients with acute ischemic stroke can be used for condition assessment and efficacy monitoring. <br /< | ||
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650 | 4 | |a Interleukin-6 | |
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653 | 0 | |a Neurology. Diseases of the nervous system | |
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700 | 0 | |a Liang WANG |e verfasserin |4 aut | |
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(DE-627)DOAJ04402231X (DE-599)DOAJ80beacd61ef24c2b9bb13fff576babe6 DE-627 ger DE-627 rakwb eng chi RC346-429 Heng YU verfasserin aut Serum inflammatory cytokines combined with NIHSS to evaluate the condition of patients with acute ischemic stroke 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <strong<Objective</strong< To explore the changes of serum inflammatory cytokines and National Institute of Health Stroke Scale (NIHSS) score in acute ischemic stroke patients and their clinical significances on patients' condition assessment. <strong<Methods</strong< The serum levels of three cytokines, including interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) and high⁃sensitivity C-reactive protein (hs-CRP), were measured and compared between 90 acute ischemic stroke patients (ischemic stroke group) and 50 healthy people (normal control group). The above-mentioned three cytokines and NIHSS scores were compared between before and after treatment in ischemic stroke group. <strong<Results</strong< Patients in ischemic stroke group were divided into three subgroups according to different infarct sizes: large (> 10 cm3), medium (5-10 cm3) and small (< 5 cm3). The serum levels of three cytokines were significantly higher in three subgroups than those in the normal control group before treatment (P < 0.01). Compared with before treatment, both the serum levels of three cytokines and the NIHSS scores in ishemic stroke patients reduced significantly after treatment (P < 0.01, for all). <strong<Conclusion</strong< Serum levels of inflammatory cytokines and NIHSS scores in patients with acute ischemic stroke can be used for condition assessment and efficacy monitoring. <br /< Brain ischemia Interleukin-6 Tumor necrosis factor-alpha C-reactive protein Neurology. Diseases of the nervous system Chong-rong LONG verfasserin aut Liang WANG verfasserin aut In Chinese Journal of Contemporary Neurology and Neurosurgery Tianjin Huanhu Hospital, 2013 13(2013), 9, Seite 801-804 (DE-627)741171848 (DE-600)2710763-2 16726731 nnns volume:13 year:2013 number:9 pages:801-804 https://doaj.org/article/80beacd61ef24c2b9bb13fff576babe6 kostenfrei http://www.cjcnn.org/index.php/cjcnn/article/view/807 kostenfrei https://doaj.org/toc/1672-6731 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2014 GBV_ILN_2106 GBV_ILN_2232 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2013 9 801-804 |
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(DE-627)DOAJ04402231X (DE-599)DOAJ80beacd61ef24c2b9bb13fff576babe6 DE-627 ger DE-627 rakwb eng chi RC346-429 Heng YU verfasserin aut Serum inflammatory cytokines combined with NIHSS to evaluate the condition of patients with acute ischemic stroke 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <strong<Objective</strong< To explore the changes of serum inflammatory cytokines and National Institute of Health Stroke Scale (NIHSS) score in acute ischemic stroke patients and their clinical significances on patients' condition assessment. <strong<Methods</strong< The serum levels of three cytokines, including interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) and high⁃sensitivity C-reactive protein (hs-CRP), were measured and compared between 90 acute ischemic stroke patients (ischemic stroke group) and 50 healthy people (normal control group). The above-mentioned three cytokines and NIHSS scores were compared between before and after treatment in ischemic stroke group. <strong<Results</strong< Patients in ischemic stroke group were divided into three subgroups according to different infarct sizes: large (> 10 cm3), medium (5-10 cm3) and small (< 5 cm3). The serum levels of three cytokines were significantly higher in three subgroups than those in the normal control group before treatment (P < 0.01). Compared with before treatment, both the serum levels of three cytokines and the NIHSS scores in ishemic stroke patients reduced significantly after treatment (P < 0.01, for all). <strong<Conclusion</strong< Serum levels of inflammatory cytokines and NIHSS scores in patients with acute ischemic stroke can be used for condition assessment and efficacy monitoring. <br /< Brain ischemia Interleukin-6 Tumor necrosis factor-alpha C-reactive protein Neurology. Diseases of the nervous system Chong-rong LONG verfasserin aut Liang WANG verfasserin aut In Chinese Journal of Contemporary Neurology and Neurosurgery Tianjin Huanhu Hospital, 2013 13(2013), 9, Seite 801-804 (DE-627)741171848 (DE-600)2710763-2 16726731 nnns volume:13 year:2013 number:9 pages:801-804 https://doaj.org/article/80beacd61ef24c2b9bb13fff576babe6 kostenfrei http://www.cjcnn.org/index.php/cjcnn/article/view/807 kostenfrei https://doaj.org/toc/1672-6731 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2014 GBV_ILN_2106 GBV_ILN_2232 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2013 9 801-804 |
allfields_unstemmed |
(DE-627)DOAJ04402231X (DE-599)DOAJ80beacd61ef24c2b9bb13fff576babe6 DE-627 ger DE-627 rakwb eng chi RC346-429 Heng YU verfasserin aut Serum inflammatory cytokines combined with NIHSS to evaluate the condition of patients with acute ischemic stroke 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <strong<Objective</strong< To explore the changes of serum inflammatory cytokines and National Institute of Health Stroke Scale (NIHSS) score in acute ischemic stroke patients and their clinical significances on patients' condition assessment. <strong<Methods</strong< The serum levels of three cytokines, including interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) and high⁃sensitivity C-reactive protein (hs-CRP), were measured and compared between 90 acute ischemic stroke patients (ischemic stroke group) and 50 healthy people (normal control group). The above-mentioned three cytokines and NIHSS scores were compared between before and after treatment in ischemic stroke group. <strong<Results</strong< Patients in ischemic stroke group were divided into three subgroups according to different infarct sizes: large (> 10 cm3), medium (5-10 cm3) and small (< 5 cm3). The serum levels of three cytokines were significantly higher in three subgroups than those in the normal control group before treatment (P < 0.01). Compared with before treatment, both the serum levels of three cytokines and the NIHSS scores in ishemic stroke patients reduced significantly after treatment (P < 0.01, for all). <strong<Conclusion</strong< Serum levels of inflammatory cytokines and NIHSS scores in patients with acute ischemic stroke can be used for condition assessment and efficacy monitoring. <br /< Brain ischemia Interleukin-6 Tumor necrosis factor-alpha C-reactive protein Neurology. Diseases of the nervous system Chong-rong LONG verfasserin aut Liang WANG verfasserin aut In Chinese Journal of Contemporary Neurology and Neurosurgery Tianjin Huanhu Hospital, 2013 13(2013), 9, Seite 801-804 (DE-627)741171848 (DE-600)2710763-2 16726731 nnns volume:13 year:2013 number:9 pages:801-804 https://doaj.org/article/80beacd61ef24c2b9bb13fff576babe6 kostenfrei http://www.cjcnn.org/index.php/cjcnn/article/view/807 kostenfrei https://doaj.org/toc/1672-6731 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2014 GBV_ILN_2106 GBV_ILN_2232 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2013 9 801-804 |
allfieldsGer |
(DE-627)DOAJ04402231X (DE-599)DOAJ80beacd61ef24c2b9bb13fff576babe6 DE-627 ger DE-627 rakwb eng chi RC346-429 Heng YU verfasserin aut Serum inflammatory cytokines combined with NIHSS to evaluate the condition of patients with acute ischemic stroke 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <strong<Objective</strong< To explore the changes of serum inflammatory cytokines and National Institute of Health Stroke Scale (NIHSS) score in acute ischemic stroke patients and their clinical significances on patients' condition assessment. <strong<Methods</strong< The serum levels of three cytokines, including interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) and high⁃sensitivity C-reactive protein (hs-CRP), were measured and compared between 90 acute ischemic stroke patients (ischemic stroke group) and 50 healthy people (normal control group). The above-mentioned three cytokines and NIHSS scores were compared between before and after treatment in ischemic stroke group. <strong<Results</strong< Patients in ischemic stroke group were divided into three subgroups according to different infarct sizes: large (> 10 cm3), medium (5-10 cm3) and small (< 5 cm3). The serum levels of three cytokines were significantly higher in three subgroups than those in the normal control group before treatment (P < 0.01). Compared with before treatment, both the serum levels of three cytokines and the NIHSS scores in ishemic stroke patients reduced significantly after treatment (P < 0.01, for all). <strong<Conclusion</strong< Serum levels of inflammatory cytokines and NIHSS scores in patients with acute ischemic stroke can be used for condition assessment and efficacy monitoring. <br /< Brain ischemia Interleukin-6 Tumor necrosis factor-alpha C-reactive protein Neurology. Diseases of the nervous system Chong-rong LONG verfasserin aut Liang WANG verfasserin aut In Chinese Journal of Contemporary Neurology and Neurosurgery Tianjin Huanhu Hospital, 2013 13(2013), 9, Seite 801-804 (DE-627)741171848 (DE-600)2710763-2 16726731 nnns volume:13 year:2013 number:9 pages:801-804 https://doaj.org/article/80beacd61ef24c2b9bb13fff576babe6 kostenfrei http://www.cjcnn.org/index.php/cjcnn/article/view/807 kostenfrei https://doaj.org/toc/1672-6731 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2014 GBV_ILN_2106 GBV_ILN_2232 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2013 9 801-804 |
allfieldsSound |
(DE-627)DOAJ04402231X (DE-599)DOAJ80beacd61ef24c2b9bb13fff576babe6 DE-627 ger DE-627 rakwb eng chi RC346-429 Heng YU verfasserin aut Serum inflammatory cytokines combined with NIHSS to evaluate the condition of patients with acute ischemic stroke 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <strong<Objective</strong< To explore the changes of serum inflammatory cytokines and National Institute of Health Stroke Scale (NIHSS) score in acute ischemic stroke patients and their clinical significances on patients' condition assessment. <strong<Methods</strong< The serum levels of three cytokines, including interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) and high⁃sensitivity C-reactive protein (hs-CRP), were measured and compared between 90 acute ischemic stroke patients (ischemic stroke group) and 50 healthy people (normal control group). The above-mentioned three cytokines and NIHSS scores were compared between before and after treatment in ischemic stroke group. <strong<Results</strong< Patients in ischemic stroke group were divided into three subgroups according to different infarct sizes: large (> 10 cm3), medium (5-10 cm3) and small (< 5 cm3). The serum levels of three cytokines were significantly higher in three subgroups than those in the normal control group before treatment (P < 0.01). Compared with before treatment, both the serum levels of three cytokines and the NIHSS scores in ishemic stroke patients reduced significantly after treatment (P < 0.01, for all). <strong<Conclusion</strong< Serum levels of inflammatory cytokines and NIHSS scores in patients with acute ischemic stroke can be used for condition assessment and efficacy monitoring. <br /< Brain ischemia Interleukin-6 Tumor necrosis factor-alpha C-reactive protein Neurology. Diseases of the nervous system Chong-rong LONG verfasserin aut Liang WANG verfasserin aut In Chinese Journal of Contemporary Neurology and Neurosurgery Tianjin Huanhu Hospital, 2013 13(2013), 9, Seite 801-804 (DE-627)741171848 (DE-600)2710763-2 16726731 nnns volume:13 year:2013 number:9 pages:801-804 https://doaj.org/article/80beacd61ef24c2b9bb13fff576babe6 kostenfrei http://www.cjcnn.org/index.php/cjcnn/article/view/807 kostenfrei https://doaj.org/toc/1672-6731 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2014 GBV_ILN_2106 GBV_ILN_2232 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2013 9 801-804 |
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The above-mentioned three cytokines and NIHSS scores were compared between before and after treatment in ischemic stroke group. <strong<Results</strong< Patients in ischemic stroke group were divided into three subgroups according to different infarct sizes: large (&gt; 10 cm3), medium (5-10 cm3) and small (&lt; 5 cm3). The serum levels of three cytokines were significantly higher in three subgroups than those in the normal control group before treatment (P &lt; 0.01). Compared with before treatment, both the serum levels of three cytokines and the NIHSS scores in ishemic stroke patients reduced significantly after treatment (P &lt; 0.01, for all). <strong<Conclusion</strong< Serum levels of inflammatory cytokines and NIHSS scores in patients with acute ischemic stroke can be used for condition assessment and efficacy monitoring. <br /<</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Brain ischemia</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Interleukin-6</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Tumor necrosis factor-alpha</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">C-reactive protein</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Neurology. 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RC346-429 Serum inflammatory cytokines combined with NIHSS to evaluate the condition of patients with acute ischemic stroke Brain ischemia Interleukin-6 Tumor necrosis factor-alpha C-reactive protein |
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Serum inflammatory cytokines combined with NIHSS to evaluate the condition of patients with acute ischemic stroke |
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serum inflammatory cytokines combined with nihss to evaluate the condition of patients with acute ischemic stroke |
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Serum inflammatory cytokines combined with NIHSS to evaluate the condition of patients with acute ischemic stroke |
abstract |
<strong<Objective</strong< To explore the changes of serum inflammatory cytokines and National Institute of Health Stroke Scale (NIHSS) score in acute ischemic stroke patients and their clinical significances on patients' condition assessment. <strong<Methods</strong< The serum levels of three cytokines, including interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) and high⁃sensitivity C-reactive protein (hs-CRP), were measured and compared between 90 acute ischemic stroke patients (ischemic stroke group) and 50 healthy people (normal control group). The above-mentioned three cytokines and NIHSS scores were compared between before and after treatment in ischemic stroke group. <strong<Results</strong< Patients in ischemic stroke group were divided into three subgroups according to different infarct sizes: large (> 10 cm3), medium (5-10 cm3) and small (< 5 cm3). The serum levels of three cytokines were significantly higher in three subgroups than those in the normal control group before treatment (P < 0.01). Compared with before treatment, both the serum levels of three cytokines and the NIHSS scores in ishemic stroke patients reduced significantly after treatment (P < 0.01, for all). <strong<Conclusion</strong< Serum levels of inflammatory cytokines and NIHSS scores in patients with acute ischemic stroke can be used for condition assessment and efficacy monitoring. <br /< |
abstractGer |
<strong<Objective</strong< To explore the changes of serum inflammatory cytokines and National Institute of Health Stroke Scale (NIHSS) score in acute ischemic stroke patients and their clinical significances on patients' condition assessment. <strong<Methods</strong< The serum levels of three cytokines, including interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) and high⁃sensitivity C-reactive protein (hs-CRP), were measured and compared between 90 acute ischemic stroke patients (ischemic stroke group) and 50 healthy people (normal control group). The above-mentioned three cytokines and NIHSS scores were compared between before and after treatment in ischemic stroke group. <strong<Results</strong< Patients in ischemic stroke group were divided into three subgroups according to different infarct sizes: large (> 10 cm3), medium (5-10 cm3) and small (< 5 cm3). The serum levels of three cytokines were significantly higher in three subgroups than those in the normal control group before treatment (P < 0.01). Compared with before treatment, both the serum levels of three cytokines and the NIHSS scores in ishemic stroke patients reduced significantly after treatment (P < 0.01, for all). <strong<Conclusion</strong< Serum levels of inflammatory cytokines and NIHSS scores in patients with acute ischemic stroke can be used for condition assessment and efficacy monitoring. <br /< |
abstract_unstemmed |
<strong<Objective</strong< To explore the changes of serum inflammatory cytokines and National Institute of Health Stroke Scale (NIHSS) score in acute ischemic stroke patients and their clinical significances on patients' condition assessment. <strong<Methods</strong< The serum levels of three cytokines, including interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) and high⁃sensitivity C-reactive protein (hs-CRP), were measured and compared between 90 acute ischemic stroke patients (ischemic stroke group) and 50 healthy people (normal control group). The above-mentioned three cytokines and NIHSS scores were compared between before and after treatment in ischemic stroke group. <strong<Results</strong< Patients in ischemic stroke group were divided into three subgroups according to different infarct sizes: large (> 10 cm3), medium (5-10 cm3) and small (< 5 cm3). The serum levels of three cytokines were significantly higher in three subgroups than those in the normal control group before treatment (P < 0.01). Compared with before treatment, both the serum levels of three cytokines and the NIHSS scores in ishemic stroke patients reduced significantly after treatment (P < 0.01, for all). <strong<Conclusion</strong< Serum levels of inflammatory cytokines and NIHSS scores in patients with acute ischemic stroke can be used for condition assessment and efficacy monitoring. <br /< |
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Serum inflammatory cytokines combined with NIHSS to evaluate the condition of patients with acute ischemic stroke |
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https://doaj.org/article/80beacd61ef24c2b9bb13fff576babe6 http://www.cjcnn.org/index.php/cjcnn/article/view/807 https://doaj.org/toc/1672-6731 |
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