Comparative assessment and monitoring of deterioration of articulatory organs using subjective and objective tools among patients with amyotrophic lateral sclerosis

Abstract Background Amyotrophic lateral sclerosis (ALS) is a fatal degenerative disease of a rapid course. In 25% of ALS sufferers, speech disorders occur as prodromal symptoms of the disease. Impaired communication affects physical health and has a negative impact on mental and emotional condition....
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Autor*in:	Wioletta Pawlukowska [verfasserIn] Bartłomiej Baumert [verfasserIn] Monika Gołąb-Janowska [verfasserIn] Agnieszka Meller [verfasserIn] Karolina Machowska-Sempruch [verfasserIn] Agnieszka Wełnicka [verfasserIn] Edyta Paczkowska [verfasserIn] Iwona Rotter [verfasserIn] Bogusław Machaliński [verfasserIn] Przemysław Nowacki [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2019

Schlagwörter:	Amyotrophic lateral sclerosis Dysarthria Speech disorders Voice Handicap Index Frenchay Dysarthria Assessment

Übergeordnetes Werk:	In: BMC Neurology - BMC, 2003, 19(2019), 1, Seite 8
Übergeordnetes Werk:	volume:19 ; year:2019 ; number:1 ; pages:8

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1186/s12883-019-1484-2

Katalog-ID:	DOAJ044486154

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520			\|a Abstract Background Amyotrophic lateral sclerosis (ALS) is a fatal degenerative disease of a rapid course. In 25% of ALS sufferers, speech disorders occur as prodromal symptoms of the disease. Impaired communication affects physical health and has a negative impact on mental and emotional condition. In this study, we assessed which domains of speech are particularly affected in ALS. Subsequently, we estimated possible correlations between the ALS patients’ subjective perception of their speech quality and an objective assessment of the speech organs carried out by an expert. Methods The study group consisted of 63 patients with sporadic ALS. The patients were examined for articulatory functions by means of Voice Handicap Index (VHI) and the Frenchay Dysarthria Assessment (FDA). Results On the basis of the VHI scores, the entire cohort was divided into 2 groups: group I (40 subjects) with mild speech impairment, and group II (23 subjects) displaying moderate and profound speech deficits. In an early phase of ALS, changes were typically reported in the tongue, lips and soft palate. The FDA and VHI-based measurements revealed a high, positive correlation between the objective and subjective evaluation of articulation quality. Conclusions Deterioration of the articulatory organs resulted in the reduction of social, physical and emotional functioning. The highly positive correlation between the VHI and FDA scales seems to indicate that the VHI questionnaire may be a reliable, self-contained tool for monitoring the course and progression of speech disorders in ALS. Trial registration NCT02193893.
650		4	\|a Amyotrophic lateral sclerosis
650		4	\|a Dysarthria
650		4	\|a Speech disorders
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650		4	\|a Frenchay Dysarthria Assessment
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allfields	10.1186/s12883-019-1484-2 doi (DE-627)DOAJ044486154 (DE-599)DOAJ2afb349fb68347bc926d42205a3dbc54 DE-627 ger DE-627 rakwb eng RC346-429 Wioletta Pawlukowska verfasserin aut Comparative assessment and monitoring of deterioration of articulatory organs using subjective and objective tools among patients with amyotrophic lateral sclerosis 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Amyotrophic lateral sclerosis (ALS) is a fatal degenerative disease of a rapid course. In 25% of ALS sufferers, speech disorders occur as prodromal symptoms of the disease. Impaired communication affects physical health and has a negative impact on mental and emotional condition. In this study, we assessed which domains of speech are particularly affected in ALS. Subsequently, we estimated possible correlations between the ALS patients’ subjective perception of their speech quality and an objective assessment of the speech organs carried out by an expert. Methods The study group consisted of 63 patients with sporadic ALS. The patients were examined for articulatory functions by means of Voice Handicap Index (VHI) and the Frenchay Dysarthria Assessment (FDA). Results On the basis of the VHI scores, the entire cohort was divided into 2 groups: group I (40 subjects) with mild speech impairment, and group II (23 subjects) displaying moderate and profound speech deficits. In an early phase of ALS, changes were typically reported in the tongue, lips and soft palate. The FDA and VHI-based measurements revealed a high, positive correlation between the objective and subjective evaluation of articulation quality. Conclusions Deterioration of the articulatory organs resulted in the reduction of social, physical and emotional functioning. The highly positive correlation between the VHI and FDA scales seems to indicate that the VHI questionnaire may be a reliable, self-contained tool for monitoring the course and progression of speech disorders in ALS. Trial registration NCT02193893. Amyotrophic lateral sclerosis Dysarthria Speech disorders Voice Handicap Index Frenchay Dysarthria Assessment Neurology. Diseases of the nervous system Bartłomiej Baumert verfasserin aut Monika Gołąb-Janowska verfasserin aut Agnieszka Meller verfasserin aut Karolina Machowska-Sempruch verfasserin aut Agnieszka Wełnicka verfasserin aut Edyta Paczkowska verfasserin aut Iwona Rotter verfasserin aut Bogusław Machaliński verfasserin aut Przemysław Nowacki verfasserin aut In BMC Neurology BMC, 2003 19(2019), 1, Seite 8 (DE-627)326643664 (DE-600)2041347-6 14712377 nnns volume:19 year:2019 number:1 pages:8 https://doi.org/10.1186/s12883-019-1484-2 kostenfrei https://doaj.org/article/2afb349fb68347bc926d42205a3dbc54 kostenfrei http://link.springer.com/article/10.1186/s12883-019-1484-2 kostenfrei https://doaj.org/toc/1471-2377 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 19 2019 1 8
spelling	10.1186/s12883-019-1484-2 doi (DE-627)DOAJ044486154 (DE-599)DOAJ2afb349fb68347bc926d42205a3dbc54 DE-627 ger DE-627 rakwb eng RC346-429 Wioletta Pawlukowska verfasserin aut Comparative assessment and monitoring of deterioration of articulatory organs using subjective and objective tools among patients with amyotrophic lateral sclerosis 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Amyotrophic lateral sclerosis (ALS) is a fatal degenerative disease of a rapid course. In 25% of ALS sufferers, speech disorders occur as prodromal symptoms of the disease. Impaired communication affects physical health and has a negative impact on mental and emotional condition. In this study, we assessed which domains of speech are particularly affected in ALS. Subsequently, we estimated possible correlations between the ALS patients’ subjective perception of their speech quality and an objective assessment of the speech organs carried out by an expert. Methods The study group consisted of 63 patients with sporadic ALS. The patients were examined for articulatory functions by means of Voice Handicap Index (VHI) and the Frenchay Dysarthria Assessment (FDA). Results On the basis of the VHI scores, the entire cohort was divided into 2 groups: group I (40 subjects) with mild speech impairment, and group II (23 subjects) displaying moderate and profound speech deficits. In an early phase of ALS, changes were typically reported in the tongue, lips and soft palate. The FDA and VHI-based measurements revealed a high, positive correlation between the objective and subjective evaluation of articulation quality. Conclusions Deterioration of the articulatory organs resulted in the reduction of social, physical and emotional functioning. The highly positive correlation between the VHI and FDA scales seems to indicate that the VHI questionnaire may be a reliable, self-contained tool for monitoring the course and progression of speech disorders in ALS. Trial registration NCT02193893. Amyotrophic lateral sclerosis Dysarthria Speech disorders Voice Handicap Index Frenchay Dysarthria Assessment Neurology. Diseases of the nervous system Bartłomiej Baumert verfasserin aut Monika Gołąb-Janowska verfasserin aut Agnieszka Meller verfasserin aut Karolina Machowska-Sempruch verfasserin aut Agnieszka Wełnicka verfasserin aut Edyta Paczkowska verfasserin aut Iwona Rotter verfasserin aut Bogusław Machaliński verfasserin aut Przemysław Nowacki verfasserin aut In BMC Neurology BMC, 2003 19(2019), 1, Seite 8 (DE-627)326643664 (DE-600)2041347-6 14712377 nnns volume:19 year:2019 number:1 pages:8 https://doi.org/10.1186/s12883-019-1484-2 kostenfrei https://doaj.org/article/2afb349fb68347bc926d42205a3dbc54 kostenfrei http://link.springer.com/article/10.1186/s12883-019-1484-2 kostenfrei https://doaj.org/toc/1471-2377 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 19 2019 1 8
allfields_unstemmed	10.1186/s12883-019-1484-2 doi (DE-627)DOAJ044486154 (DE-599)DOAJ2afb349fb68347bc926d42205a3dbc54 DE-627 ger DE-627 rakwb eng RC346-429 Wioletta Pawlukowska verfasserin aut Comparative assessment and monitoring of deterioration of articulatory organs using subjective and objective tools among patients with amyotrophic lateral sclerosis 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Amyotrophic lateral sclerosis (ALS) is a fatal degenerative disease of a rapid course. In 25% of ALS sufferers, speech disorders occur as prodromal symptoms of the disease. Impaired communication affects physical health and has a negative impact on mental and emotional condition. In this study, we assessed which domains of speech are particularly affected in ALS. Subsequently, we estimated possible correlations between the ALS patients’ subjective perception of their speech quality and an objective assessment of the speech organs carried out by an expert. Methods The study group consisted of 63 patients with sporadic ALS. The patients were examined for articulatory functions by means of Voice Handicap Index (VHI) and the Frenchay Dysarthria Assessment (FDA). Results On the basis of the VHI scores, the entire cohort was divided into 2 groups: group I (40 subjects) with mild speech impairment, and group II (23 subjects) displaying moderate and profound speech deficits. In an early phase of ALS, changes were typically reported in the tongue, lips and soft palate. The FDA and VHI-based measurements revealed a high, positive correlation between the objective and subjective evaluation of articulation quality. Conclusions Deterioration of the articulatory organs resulted in the reduction of social, physical and emotional functioning. The highly positive correlation between the VHI and FDA scales seems to indicate that the VHI questionnaire may be a reliable, self-contained tool for monitoring the course and progression of speech disorders in ALS. Trial registration NCT02193893. Amyotrophic lateral sclerosis Dysarthria Speech disorders Voice Handicap Index Frenchay Dysarthria Assessment Neurology. Diseases of the nervous system Bartłomiej Baumert verfasserin aut Monika Gołąb-Janowska verfasserin aut Agnieszka Meller verfasserin aut Karolina Machowska-Sempruch verfasserin aut Agnieszka Wełnicka verfasserin aut Edyta Paczkowska verfasserin aut Iwona Rotter verfasserin aut Bogusław Machaliński verfasserin aut Przemysław Nowacki verfasserin aut In BMC Neurology BMC, 2003 19(2019), 1, Seite 8 (DE-627)326643664 (DE-600)2041347-6 14712377 nnns volume:19 year:2019 number:1 pages:8 https://doi.org/10.1186/s12883-019-1484-2 kostenfrei https://doaj.org/article/2afb349fb68347bc926d42205a3dbc54 kostenfrei http://link.springer.com/article/10.1186/s12883-019-1484-2 kostenfrei https://doaj.org/toc/1471-2377 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 19 2019 1 8
allfieldsGer	10.1186/s12883-019-1484-2 doi (DE-627)DOAJ044486154 (DE-599)DOAJ2afb349fb68347bc926d42205a3dbc54 DE-627 ger DE-627 rakwb eng RC346-429 Wioletta Pawlukowska verfasserin aut Comparative assessment and monitoring of deterioration of articulatory organs using subjective and objective tools among patients with amyotrophic lateral sclerosis 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Amyotrophic lateral sclerosis (ALS) is a fatal degenerative disease of a rapid course. In 25% of ALS sufferers, speech disorders occur as prodromal symptoms of the disease. Impaired communication affects physical health and has a negative impact on mental and emotional condition. In this study, we assessed which domains of speech are particularly affected in ALS. Subsequently, we estimated possible correlations between the ALS patients’ subjective perception of their speech quality and an objective assessment of the speech organs carried out by an expert. Methods The study group consisted of 63 patients with sporadic ALS. The patients were examined for articulatory functions by means of Voice Handicap Index (VHI) and the Frenchay Dysarthria Assessment (FDA). Results On the basis of the VHI scores, the entire cohort was divided into 2 groups: group I (40 subjects) with mild speech impairment, and group II (23 subjects) displaying moderate and profound speech deficits. In an early phase of ALS, changes were typically reported in the tongue, lips and soft palate. The FDA and VHI-based measurements revealed a high, positive correlation between the objective and subjective evaluation of articulation quality. Conclusions Deterioration of the articulatory organs resulted in the reduction of social, physical and emotional functioning. The highly positive correlation between the VHI and FDA scales seems to indicate that the VHI questionnaire may be a reliable, self-contained tool for monitoring the course and progression of speech disorders in ALS. Trial registration NCT02193893. Amyotrophic lateral sclerosis Dysarthria Speech disorders Voice Handicap Index Frenchay Dysarthria Assessment Neurology. Diseases of the nervous system Bartłomiej Baumert verfasserin aut Monika Gołąb-Janowska verfasserin aut Agnieszka Meller verfasserin aut Karolina Machowska-Sempruch verfasserin aut Agnieszka Wełnicka verfasserin aut Edyta Paczkowska verfasserin aut Iwona Rotter verfasserin aut Bogusław Machaliński verfasserin aut Przemysław Nowacki verfasserin aut In BMC Neurology BMC, 2003 19(2019), 1, Seite 8 (DE-627)326643664 (DE-600)2041347-6 14712377 nnns volume:19 year:2019 number:1 pages:8 https://doi.org/10.1186/s12883-019-1484-2 kostenfrei https://doaj.org/article/2afb349fb68347bc926d42205a3dbc54 kostenfrei http://link.springer.com/article/10.1186/s12883-019-1484-2 kostenfrei https://doaj.org/toc/1471-2377 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 19 2019 1 8
allfieldsSound	10.1186/s12883-019-1484-2 doi (DE-627)DOAJ044486154 (DE-599)DOAJ2afb349fb68347bc926d42205a3dbc54 DE-627 ger DE-627 rakwb eng RC346-429 Wioletta Pawlukowska verfasserin aut Comparative assessment and monitoring of deterioration of articulatory organs using subjective and objective tools among patients with amyotrophic lateral sclerosis 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Amyotrophic lateral sclerosis (ALS) is a fatal degenerative disease of a rapid course. In 25% of ALS sufferers, speech disorders occur as prodromal symptoms of the disease. Impaired communication affects physical health and has a negative impact on mental and emotional condition. In this study, we assessed which domains of speech are particularly affected in ALS. Subsequently, we estimated possible correlations between the ALS patients’ subjective perception of their speech quality and an objective assessment of the speech organs carried out by an expert. Methods The study group consisted of 63 patients with sporadic ALS. The patients were examined for articulatory functions by means of Voice Handicap Index (VHI) and the Frenchay Dysarthria Assessment (FDA). Results On the basis of the VHI scores, the entire cohort was divided into 2 groups: group I (40 subjects) with mild speech impairment, and group II (23 subjects) displaying moderate and profound speech deficits. In an early phase of ALS, changes were typically reported in the tongue, lips and soft palate. The FDA and VHI-based measurements revealed a high, positive correlation between the objective and subjective evaluation of articulation quality. Conclusions Deterioration of the articulatory organs resulted in the reduction of social, physical and emotional functioning. The highly positive correlation between the VHI and FDA scales seems to indicate that the VHI questionnaire may be a reliable, self-contained tool for monitoring the course and progression of speech disorders in ALS. Trial registration NCT02193893. Amyotrophic lateral sclerosis Dysarthria Speech disorders Voice Handicap Index Frenchay Dysarthria Assessment Neurology. Diseases of the nervous system Bartłomiej Baumert verfasserin aut Monika Gołąb-Janowska verfasserin aut Agnieszka Meller verfasserin aut Karolina Machowska-Sempruch verfasserin aut Agnieszka Wełnicka verfasserin aut Edyta Paczkowska verfasserin aut Iwona Rotter verfasserin aut Bogusław Machaliński verfasserin aut Przemysław Nowacki verfasserin aut In BMC Neurology BMC, 2003 19(2019), 1, Seite 8 (DE-627)326643664 (DE-600)2041347-6 14712377 nnns volume:19 year:2019 number:1 pages:8 https://doi.org/10.1186/s12883-019-1484-2 kostenfrei https://doaj.org/article/2afb349fb68347bc926d42205a3dbc54 kostenfrei http://link.springer.com/article/10.1186/s12883-019-1484-2 kostenfrei https://doaj.org/toc/1471-2377 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 19 2019 1 8
language	English
source	In BMC Neurology 19(2019), 1, Seite 8 volume:19 year:2019 number:1 pages:8
sourceStr	In BMC Neurology 19(2019), 1, Seite 8 volume:19 year:2019 number:1 pages:8
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Amyotrophic lateral sclerosis Dysarthria Speech disorders Voice Handicap Index Frenchay Dysarthria Assessment Neurology. Diseases of the nervous system
isfreeaccess_bool	true
container_title	BMC Neurology
authorswithroles_txt_mv	Wioletta Pawlukowska @@aut@@ Bartłomiej Baumert @@aut@@ Monika Gołąb-Janowska @@aut@@ Agnieszka Meller @@aut@@ Karolina Machowska-Sempruch @@aut@@ Agnieszka Wełnicka @@aut@@ Edyta Paczkowska @@aut@@ Iwona Rotter @@aut@@ Bogusław Machaliński @@aut@@ Przemysław Nowacki @@aut@@
publishDateDaySort_date	2019-01-01T00:00:00Z
hierarchy_top_id	326643664
id	DOAJ044486154
language_de	englisch
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callnumber-first	R - Medicine
author	Wioletta Pawlukowska
spellingShingle	Wioletta Pawlukowska misc RC346-429 misc Amyotrophic lateral sclerosis misc Dysarthria misc Speech disorders misc Voice Handicap Index misc Frenchay Dysarthria Assessment misc Neurology. Diseases of the nervous system Comparative assessment and monitoring of deterioration of articulatory organs using subjective and objective tools among patients with amyotrophic lateral sclerosis
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topic_title	RC346-429 Comparative assessment and monitoring of deterioration of articulatory organs using subjective and objective tools among patients with amyotrophic lateral sclerosis Amyotrophic lateral sclerosis Dysarthria Speech disorders Voice Handicap Index Frenchay Dysarthria Assessment
topic	misc RC346-429 misc Amyotrophic lateral sclerosis misc Dysarthria misc Speech disorders misc Voice Handicap Index misc Frenchay Dysarthria Assessment misc Neurology. Diseases of the nervous system
topic_unstemmed	misc RC346-429 misc Amyotrophic lateral sclerosis misc Dysarthria misc Speech disorders misc Voice Handicap Index misc Frenchay Dysarthria Assessment misc Neurology. Diseases of the nervous system
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title	Comparative assessment and monitoring of deterioration of articulatory organs using subjective and objective tools among patients with amyotrophic lateral sclerosis
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title_full	Comparative assessment and monitoring of deterioration of articulatory organs using subjective and objective tools among patients with amyotrophic lateral sclerosis
author_sort	Wioletta Pawlukowska
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author_browse	Wioletta Pawlukowska Bartłomiej Baumert Monika Gołąb-Janowska Agnieszka Meller Karolina Machowska-Sempruch Agnieszka Wełnicka Edyta Paczkowska Iwona Rotter Bogusław Machaliński Przemysław Nowacki
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title_sort	comparative assessment and monitoring of deterioration of articulatory organs using subjective and objective tools among patients with amyotrophic lateral sclerosis
callnumber	RC346-429
title_auth	Comparative assessment and monitoring of deterioration of articulatory organs using subjective and objective tools among patients with amyotrophic lateral sclerosis
abstract	Abstract Background Amyotrophic lateral sclerosis (ALS) is a fatal degenerative disease of a rapid course. In 25% of ALS sufferers, speech disorders occur as prodromal symptoms of the disease. Impaired communication affects physical health and has a negative impact on mental and emotional condition. In this study, we assessed which domains of speech are particularly affected in ALS. Subsequently, we estimated possible correlations between the ALS patients’ subjective perception of their speech quality and an objective assessment of the speech organs carried out by an expert. Methods The study group consisted of 63 patients with sporadic ALS. The patients were examined for articulatory functions by means of Voice Handicap Index (VHI) and the Frenchay Dysarthria Assessment (FDA). Results On the basis of the VHI scores, the entire cohort was divided into 2 groups: group I (40 subjects) with mild speech impairment, and group II (23 subjects) displaying moderate and profound speech deficits. In an early phase of ALS, changes were typically reported in the tongue, lips and soft palate. The FDA and VHI-based measurements revealed a high, positive correlation between the objective and subjective evaluation of articulation quality. Conclusions Deterioration of the articulatory organs resulted in the reduction of social, physical and emotional functioning. The highly positive correlation between the VHI and FDA scales seems to indicate that the VHI questionnaire may be a reliable, self-contained tool for monitoring the course and progression of speech disorders in ALS. Trial registration NCT02193893.
abstractGer	Abstract Background Amyotrophic lateral sclerosis (ALS) is a fatal degenerative disease of a rapid course. In 25% of ALS sufferers, speech disorders occur as prodromal symptoms of the disease. Impaired communication affects physical health and has a negative impact on mental and emotional condition. In this study, we assessed which domains of speech are particularly affected in ALS. Subsequently, we estimated possible correlations between the ALS patients’ subjective perception of their speech quality and an objective assessment of the speech organs carried out by an expert. Methods The study group consisted of 63 patients with sporadic ALS. The patients were examined for articulatory functions by means of Voice Handicap Index (VHI) and the Frenchay Dysarthria Assessment (FDA). Results On the basis of the VHI scores, the entire cohort was divided into 2 groups: group I (40 subjects) with mild speech impairment, and group II (23 subjects) displaying moderate and profound speech deficits. In an early phase of ALS, changes were typically reported in the tongue, lips and soft palate. The FDA and VHI-based measurements revealed a high, positive correlation between the objective and subjective evaluation of articulation quality. Conclusions Deterioration of the articulatory organs resulted in the reduction of social, physical and emotional functioning. The highly positive correlation between the VHI and FDA scales seems to indicate that the VHI questionnaire may be a reliable, self-contained tool for monitoring the course and progression of speech disorders in ALS. Trial registration NCT02193893.
abstract_unstemmed	Abstract Background Amyotrophic lateral sclerosis (ALS) is a fatal degenerative disease of a rapid course. In 25% of ALS sufferers, speech disorders occur as prodromal symptoms of the disease. Impaired communication affects physical health and has a negative impact on mental and emotional condition. In this study, we assessed which domains of speech are particularly affected in ALS. Subsequently, we estimated possible correlations between the ALS patients’ subjective perception of their speech quality and an objective assessment of the speech organs carried out by an expert. Methods The study group consisted of 63 patients with sporadic ALS. The patients were examined for articulatory functions by means of Voice Handicap Index (VHI) and the Frenchay Dysarthria Assessment (FDA). Results On the basis of the VHI scores, the entire cohort was divided into 2 groups: group I (40 subjects) with mild speech impairment, and group II (23 subjects) displaying moderate and profound speech deficits. In an early phase of ALS, changes were typically reported in the tongue, lips and soft palate. The FDA and VHI-based measurements revealed a high, positive correlation between the objective and subjective evaluation of articulation quality. Conclusions Deterioration of the articulatory organs resulted in the reduction of social, physical and emotional functioning. The highly positive correlation between the VHI and FDA scales seems to indicate that the VHI questionnaire may be a reliable, self-contained tool for monitoring the course and progression of speech disorders in ALS. Trial registration NCT02193893.
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title_short	Comparative assessment and monitoring of deterioration of articulatory organs using subjective and objective tools among patients with amyotrophic lateral sclerosis
url	https://doi.org/10.1186/s12883-019-1484-2 https://doaj.org/article/2afb349fb68347bc926d42205a3dbc54 http://link.springer.com/article/10.1186/s12883-019-1484-2 https://doaj.org/toc/1471-2377
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author2Str	Bartłomiej Baumert Monika Gołąb-Janowska Agnieszka Meller Karolina Machowska-Sempruch Agnieszka Wełnicka Edyta Paczkowska Iwona Rotter Bogusław Machaliński Przemysław Nowacki
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Comparative assessment and monitoring of deterioration of articulatory organs using subjective and objective tools among patients with amyotrophic lateral sclerosis

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