Tumor banks: the cornerstone of basic research in urology

PURPOSE: Tumor banks have the primary responsibility for collecting, cataloging, storing and disseminating samples of tissues, cells and fluids, which are used by researchers to identify diagnostic molecular markers, prognostic indicators and therapeutic targets. The objective of this review was to...
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Autor*in:	Sabrina T. Reis [verfasserIn] Emanoela B. Feitosa [verfasserIn] Jose Pontes-Junior [verfasserIn] Camila C. Marin [verfasserIn] Daniel k. Abe [verfasserIn] Alexandre Crippa [verfasserIn] Alberto A. Antunes [verfasserIn] Adriano J. Nesrallah [verfasserIn] Luiz C. Oliveira [verfasserIn] Leopoldo A. Ribeiro-Filho [verfasserIn] Miguel Srougi [verfasserIn] Katia R. M. Leite [verfasserIn] Marcos F. Dall’Oglio [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2010

Schlagwörter:	biological specimen banks urogenital neoplasms tissue banks pathology molecular biology

Übergeordnetes Werk:	In: International Brazilian Journal of Urology - Sociedade Brasileira de Urologia, 2004, 36(2010), 3, Seite 348-354
Übergeordnetes Werk:	volume:36 ; year:2010 ; number:3 ; pages:348-354

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.1590/S1677-55382010000300012

Katalog-ID:	DOAJ044496362

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allfields	10.1590/S1677-55382010000300012 doi (DE-627)DOAJ044496362 (DE-599)DOAJc6d60900e1ad4133a0c276df5da6ed3d DE-627 ger DE-627 rakwb eng RC870-923 Sabrina T. Reis verfasserin aut Tumor banks: the cornerstone of basic research in urology 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier PURPOSE: Tumor banks have the primary responsibility for collecting, cataloging, storing and disseminating samples of tissues, cells and fluids, which are used by researchers to identify diagnostic molecular markers, prognostic indicators and therapeutic targets. The objective of this review was to describe a simple, reliable and reproducible protocol for obtaining and storing samples of urological tumors. MATERIALS AND METHODS: Urogenital tumor tissues were collected by the surgeons from the Urology Division of University of Sao Paulo Medical School. The obtained surgical specimens were immediately placed in liquid nitrogen, dry ice or in a tube containing RNAlater ®, and then stored by cryopreservation (-80°C). A mirror fragment was fixed in 10% formalin processed routinely and embedded in Paraplast®. RESULTS: We developed a protocol for the collection, cataloging, storage, conservation and use of tumor samples. During a period of one year the Urological Tumor Bank of the Urology Division stored 274 samples of prostate, bladder, kidney, penis and testicle tumors of different histological types, 74 urine and 271 serum samples. CONCLUSIONS: Having biological materials characterized and available along with the clinical patient information provides an integrated portrait of the patients and their diseases facilitating advances in molecular biology. It also promotes the development of translational research improving methods of diagnosis and cancer treatment. biological specimen banks urogenital neoplasms tissue banks pathology molecular biology Diseases of the genitourinary system. Urology Emanoela B. Feitosa verfasserin aut Jose Pontes-Junior verfasserin aut Camila C. Marin verfasserin aut Daniel k. Abe verfasserin aut Alexandre Crippa verfasserin aut Alberto A. Antunes verfasserin aut Adriano J. Nesrallah verfasserin aut Luiz C. Oliveira verfasserin aut Leopoldo A. Ribeiro-Filho verfasserin aut Miguel Srougi verfasserin aut Katia R. M. Leite verfasserin aut Marcos F. Dall’Oglio verfasserin aut In International Brazilian Journal of Urology Sociedade Brasileira de Urologia, 2004 36(2010), 3, Seite 348-354 (DE-627)394567234 (DE-600)2160867-2 16776119 nnns volume:36 year:2010 number:3 pages:348-354 https://doi.org/10.1590/S1677-55382010000300012 kostenfrei https://doaj.org/article/c6d60900e1ad4133a0c276df5da6ed3d kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382010000300012 kostenfrei https://doaj.org/toc/1677-5538 Journal toc kostenfrei https://doaj.org/toc/1677-6119 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 36 2010 3 348-354
spelling	10.1590/S1677-55382010000300012 doi (DE-627)DOAJ044496362 (DE-599)DOAJc6d60900e1ad4133a0c276df5da6ed3d DE-627 ger DE-627 rakwb eng RC870-923 Sabrina T. Reis verfasserin aut Tumor banks: the cornerstone of basic research in urology 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier PURPOSE: Tumor banks have the primary responsibility for collecting, cataloging, storing and disseminating samples of tissues, cells and fluids, which are used by researchers to identify diagnostic molecular markers, prognostic indicators and therapeutic targets. The objective of this review was to describe a simple, reliable and reproducible protocol for obtaining and storing samples of urological tumors. MATERIALS AND METHODS: Urogenital tumor tissues were collected by the surgeons from the Urology Division of University of Sao Paulo Medical School. The obtained surgical specimens were immediately placed in liquid nitrogen, dry ice or in a tube containing RNAlater ®, and then stored by cryopreservation (-80°C). A mirror fragment was fixed in 10% formalin processed routinely and embedded in Paraplast®. RESULTS: We developed a protocol for the collection, cataloging, storage, conservation and use of tumor samples. During a period of one year the Urological Tumor Bank of the Urology Division stored 274 samples of prostate, bladder, kidney, penis and testicle tumors of different histological types, 74 urine and 271 serum samples. CONCLUSIONS: Having biological materials characterized and available along with the clinical patient information provides an integrated portrait of the patients and their diseases facilitating advances in molecular biology. It also promotes the development of translational research improving methods of diagnosis and cancer treatment. biological specimen banks urogenital neoplasms tissue banks pathology molecular biology Diseases of the genitourinary system. Urology Emanoela B. Feitosa verfasserin aut Jose Pontes-Junior verfasserin aut Camila C. Marin verfasserin aut Daniel k. Abe verfasserin aut Alexandre Crippa verfasserin aut Alberto A. Antunes verfasserin aut Adriano J. Nesrallah verfasserin aut Luiz C. Oliveira verfasserin aut Leopoldo A. Ribeiro-Filho verfasserin aut Miguel Srougi verfasserin aut Katia R. M. Leite verfasserin aut Marcos F. Dall’Oglio verfasserin aut In International Brazilian Journal of Urology Sociedade Brasileira de Urologia, 2004 36(2010), 3, Seite 348-354 (DE-627)394567234 (DE-600)2160867-2 16776119 nnns volume:36 year:2010 number:3 pages:348-354 https://doi.org/10.1590/S1677-55382010000300012 kostenfrei https://doaj.org/article/c6d60900e1ad4133a0c276df5da6ed3d kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382010000300012 kostenfrei https://doaj.org/toc/1677-5538 Journal toc kostenfrei https://doaj.org/toc/1677-6119 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 36 2010 3 348-354
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allfieldsGer	10.1590/S1677-55382010000300012 doi (DE-627)DOAJ044496362 (DE-599)DOAJc6d60900e1ad4133a0c276df5da6ed3d DE-627 ger DE-627 rakwb eng RC870-923 Sabrina T. Reis verfasserin aut Tumor banks: the cornerstone of basic research in urology 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier PURPOSE: Tumor banks have the primary responsibility for collecting, cataloging, storing and disseminating samples of tissues, cells and fluids, which are used by researchers to identify diagnostic molecular markers, prognostic indicators and therapeutic targets. The objective of this review was to describe a simple, reliable and reproducible protocol for obtaining and storing samples of urological tumors. MATERIALS AND METHODS: Urogenital tumor tissues were collected by the surgeons from the Urology Division of University of Sao Paulo Medical School. The obtained surgical specimens were immediately placed in liquid nitrogen, dry ice or in a tube containing RNAlater ®, and then stored by cryopreservation (-80°C). A mirror fragment was fixed in 10% formalin processed routinely and embedded in Paraplast®. RESULTS: We developed a protocol for the collection, cataloging, storage, conservation and use of tumor samples. During a period of one year the Urological Tumor Bank of the Urology Division stored 274 samples of prostate, bladder, kidney, penis and testicle tumors of different histological types, 74 urine and 271 serum samples. CONCLUSIONS: Having biological materials characterized and available along with the clinical patient information provides an integrated portrait of the patients and their diseases facilitating advances in molecular biology. It also promotes the development of translational research improving methods of diagnosis and cancer treatment. biological specimen banks urogenital neoplasms tissue banks pathology molecular biology Diseases of the genitourinary system. Urology Emanoela B. Feitosa verfasserin aut Jose Pontes-Junior verfasserin aut Camila C. Marin verfasserin aut Daniel k. Abe verfasserin aut Alexandre Crippa verfasserin aut Alberto A. Antunes verfasserin aut Adriano J. Nesrallah verfasserin aut Luiz C. Oliveira verfasserin aut Leopoldo A. Ribeiro-Filho verfasserin aut Miguel Srougi verfasserin aut Katia R. M. Leite verfasserin aut Marcos F. Dall’Oglio verfasserin aut In International Brazilian Journal of Urology Sociedade Brasileira de Urologia, 2004 36(2010), 3, Seite 348-354 (DE-627)394567234 (DE-600)2160867-2 16776119 nnns volume:36 year:2010 number:3 pages:348-354 https://doi.org/10.1590/S1677-55382010000300012 kostenfrei https://doaj.org/article/c6d60900e1ad4133a0c276df5da6ed3d kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382010000300012 kostenfrei https://doaj.org/toc/1677-5538 Journal toc kostenfrei https://doaj.org/toc/1677-6119 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 36 2010 3 348-354
allfieldsSound	10.1590/S1677-55382010000300012 doi (DE-627)DOAJ044496362 (DE-599)DOAJc6d60900e1ad4133a0c276df5da6ed3d DE-627 ger DE-627 rakwb eng RC870-923 Sabrina T. Reis verfasserin aut Tumor banks: the cornerstone of basic research in urology 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier PURPOSE: Tumor banks have the primary responsibility for collecting, cataloging, storing and disseminating samples of tissues, cells and fluids, which are used by researchers to identify diagnostic molecular markers, prognostic indicators and therapeutic targets. The objective of this review was to describe a simple, reliable and reproducible protocol for obtaining and storing samples of urological tumors. MATERIALS AND METHODS: Urogenital tumor tissues were collected by the surgeons from the Urology Division of University of Sao Paulo Medical School. The obtained surgical specimens were immediately placed in liquid nitrogen, dry ice or in a tube containing RNAlater ®, and then stored by cryopreservation (-80°C). A mirror fragment was fixed in 10% formalin processed routinely and embedded in Paraplast®. RESULTS: We developed a protocol for the collection, cataloging, storage, conservation and use of tumor samples. During a period of one year the Urological Tumor Bank of the Urology Division stored 274 samples of prostate, bladder, kidney, penis and testicle tumors of different histological types, 74 urine and 271 serum samples. CONCLUSIONS: Having biological materials characterized and available along with the clinical patient information provides an integrated portrait of the patients and their diseases facilitating advances in molecular biology. It also promotes the development of translational research improving methods of diagnosis and cancer treatment. biological specimen banks urogenital neoplasms tissue banks pathology molecular biology Diseases of the genitourinary system. Urology Emanoela B. Feitosa verfasserin aut Jose Pontes-Junior verfasserin aut Camila C. Marin verfasserin aut Daniel k. Abe verfasserin aut Alexandre Crippa verfasserin aut Alberto A. Antunes verfasserin aut Adriano J. Nesrallah verfasserin aut Luiz C. Oliveira verfasserin aut Leopoldo A. Ribeiro-Filho verfasserin aut Miguel Srougi verfasserin aut Katia R. M. Leite verfasserin aut Marcos F. Dall’Oglio verfasserin aut In International Brazilian Journal of Urology Sociedade Brasileira de Urologia, 2004 36(2010), 3, Seite 348-354 (DE-627)394567234 (DE-600)2160867-2 16776119 nnns volume:36 year:2010 number:3 pages:348-354 https://doi.org/10.1590/S1677-55382010000300012 kostenfrei https://doaj.org/article/c6d60900e1ad4133a0c276df5da6ed3d kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382010000300012 kostenfrei https://doaj.org/toc/1677-5538 Journal toc kostenfrei https://doaj.org/toc/1677-6119 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 36 2010 3 348-354
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author	Sabrina T. Reis
spellingShingle	Sabrina T. Reis misc RC870-923 misc biological specimen banks misc urogenital neoplasms misc tissue banks misc pathology misc molecular biology misc Diseases of the genitourinary system. Urology Tumor banks: the cornerstone of basic research in urology
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topic	misc RC870-923 misc biological specimen banks misc urogenital neoplasms misc tissue banks misc pathology misc molecular biology misc Diseases of the genitourinary system. Urology
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title	Tumor banks: the cornerstone of basic research in urology
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author_browse	Sabrina T. Reis Emanoela B. Feitosa Jose Pontes-Junior Camila C. Marin Daniel k. Abe Alexandre Crippa Alberto A. Antunes Adriano J. Nesrallah Luiz C. Oliveira Leopoldo A. Ribeiro-Filho Miguel Srougi Katia R. M. Leite Marcos F. Dall’Oglio
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title_sort	tumor banks: the cornerstone of basic research in urology
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title_auth	Tumor banks: the cornerstone of basic research in urology
abstract	PURPOSE: Tumor banks have the primary responsibility for collecting, cataloging, storing and disseminating samples of tissues, cells and fluids, which are used by researchers to identify diagnostic molecular markers, prognostic indicators and therapeutic targets. The objective of this review was to describe a simple, reliable and reproducible protocol for obtaining and storing samples of urological tumors. MATERIALS AND METHODS: Urogenital tumor tissues were collected by the surgeons from the Urology Division of University of Sao Paulo Medical School. The obtained surgical specimens were immediately placed in liquid nitrogen, dry ice or in a tube containing RNAlater ®, and then stored by cryopreservation (-80°C). A mirror fragment was fixed in 10% formalin processed routinely and embedded in Paraplast®. RESULTS: We developed a protocol for the collection, cataloging, storage, conservation and use of tumor samples. During a period of one year the Urological Tumor Bank of the Urology Division stored 274 samples of prostate, bladder, kidney, penis and testicle tumors of different histological types, 74 urine and 271 serum samples. CONCLUSIONS: Having biological materials characterized and available along with the clinical patient information provides an integrated portrait of the patients and their diseases facilitating advances in molecular biology. It also promotes the development of translational research improving methods of diagnosis and cancer treatment.
abstractGer	PURPOSE: Tumor banks have the primary responsibility for collecting, cataloging, storing and disseminating samples of tissues, cells and fluids, which are used by researchers to identify diagnostic molecular markers, prognostic indicators and therapeutic targets. The objective of this review was to describe a simple, reliable and reproducible protocol for obtaining and storing samples of urological tumors. MATERIALS AND METHODS: Urogenital tumor tissues were collected by the surgeons from the Urology Division of University of Sao Paulo Medical School. The obtained surgical specimens were immediately placed in liquid nitrogen, dry ice or in a tube containing RNAlater ®, and then stored by cryopreservation (-80°C). A mirror fragment was fixed in 10% formalin processed routinely and embedded in Paraplast®. RESULTS: We developed a protocol for the collection, cataloging, storage, conservation and use of tumor samples. During a period of one year the Urological Tumor Bank of the Urology Division stored 274 samples of prostate, bladder, kidney, penis and testicle tumors of different histological types, 74 urine and 271 serum samples. CONCLUSIONS: Having biological materials characterized and available along with the clinical patient information provides an integrated portrait of the patients and their diseases facilitating advances in molecular biology. It also promotes the development of translational research improving methods of diagnosis and cancer treatment.
abstract_unstemmed	PURPOSE: Tumor banks have the primary responsibility for collecting, cataloging, storing and disseminating samples of tissues, cells and fluids, which are used by researchers to identify diagnostic molecular markers, prognostic indicators and therapeutic targets. The objective of this review was to describe a simple, reliable and reproducible protocol for obtaining and storing samples of urological tumors. MATERIALS AND METHODS: Urogenital tumor tissues were collected by the surgeons from the Urology Division of University of Sao Paulo Medical School. The obtained surgical specimens were immediately placed in liquid nitrogen, dry ice or in a tube containing RNAlater ®, and then stored by cryopreservation (-80°C). A mirror fragment was fixed in 10% formalin processed routinely and embedded in Paraplast®. RESULTS: We developed a protocol for the collection, cataloging, storage, conservation and use of tumor samples. During a period of one year the Urological Tumor Bank of the Urology Division stored 274 samples of prostate, bladder, kidney, penis and testicle tumors of different histological types, 74 urine and 271 serum samples. CONCLUSIONS: Having biological materials characterized and available along with the clinical patient information provides an integrated portrait of the patients and their diseases facilitating advances in molecular biology. It also promotes the development of translational research improving methods of diagnosis and cancer treatment.
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doi_str	10.1590/S1677-55382010000300012
callnumber-a	RC870-923
up_date	2024-07-03T23:17:12.223Z
_version_	1803601714582913024
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Reis</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Tumor banks: the cornerstone of basic research in urology</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2010</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">PURPOSE: Tumor banks have the primary responsibility for collecting, cataloging, storing and disseminating samples of tissues, cells and fluids, which are used by researchers to identify diagnostic molecular markers, prognostic indicators and therapeutic targets. The objective of this review was to describe a simple, reliable and reproducible protocol for obtaining and storing samples of urological tumors. MATERIALS AND METHODS: Urogenital tumor tissues were collected by the surgeons from the Urology Division of University of Sao Paulo Medical School. The obtained surgical specimens were immediately placed in liquid nitrogen, dry ice or in a tube containing RNAlater ®, and then stored by cryopreservation (-80°C). A mirror fragment was fixed in 10% formalin processed routinely and embedded in Paraplast®. RESULTS: We developed a protocol for the collection, cataloging, storage, conservation and use of tumor samples. During a period of one year the Urological Tumor Bank of the Urology Division stored 274 samples of prostate, bladder, kidney, penis and testicle tumors of different histological types, 74 urine and 271 serum samples. 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