Evaluation of antioxidant, antibacterial and anticancer effects of the Zinc oxide nanoparticles biosynthesized by Amaranthus cruentus L.
Background: Nanoparticles are effective in treating the cancer disease due to their antioxidant, Antibacterial and the ability to produce toxicity in the cancer cells. This study aimed to evaluation of cytotoxic, antioxidant and antibacterial effects of zinc oxide nanoparticles synthesized by Amaran...
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Gespeichert in:
| Autor*in: |
Behjati-Moghaddam M [verfasserIn] Neamati A [verfasserIn] Yousefi-Rad H [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Persisch |
| Erschienen: |
2020 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
In: Fiyz̤ - Kashan University of Medical Sciences and Health Services, 2017, 24(2020), 2, Seite 133-141 |
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| Übergeordnetes Werk: |
volume:24 ; year:2020 ; number:2 ; pages:133-141 |
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DOAJ045035857 |
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| 520 | |a Background: Nanoparticles are effective in treating the cancer disease due to their antioxidant, Antibacterial and the ability to produce toxicity in the cancer cells. This study aimed to evaluation of cytotoxic, antioxidant and antibacterial effects of zinc oxide nanoparticles synthesized by Amaranthus cruentus. Materials and Methods: This study was performed in vitro. The cytotoxic effects of biosynthesized ZnO nanoparticles were evaluated against the cancer cell line MDA-MB-231 and the normal cell line HUVEC by MTT assay. Also, antioxidant properties of these nanoparticles were evaluated by assays the DPPH and ABTS. Statistical analysis was performed by SPSS software and one way ANOVA. Antibacterial activity was also evaluated by the disc diffusion method on the gram-positive bacteria Staphylococcus aureus and gram-negative Pseudomonas aeruginosa. Results: The result of MTT assay showed that IC50 was about 32µg/ml in 48 hours after treatment of the breast cancer cells by nanoparticles while the viability of the normal cell line was 94% in the similar concentration of nanoparticles. The results of the antioxidant test showed that nanoparticles at a concentration of 1000µg/ml were able to inhibit 50% of ABTS free radicals, but they exhibited a slight potential for DPPH free radicals inhibition. Also, they had an inhibitory effect on Staphylococcus aureus and Pseudomonas aeruginosa growth. Conclusion: The results showed that ZnO nanoparticles biosynthesized by Amaranthus cruentus can have antioxidant, antibacterial and anti- cancer activities. | ||
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(DE-627)DOAJ045035857 (DE-599)DOAJ3322f9f569794bcaab2730a102b45479 DE-627 ger DE-627 rakwb per R5-920 Behjati-Moghaddam M verfasserin aut Evaluation of antioxidant, antibacterial and anticancer effects of the Zinc oxide nanoparticles biosynthesized by Amaranthus cruentus L. 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Nanoparticles are effective in treating the cancer disease due to their antioxidant, Antibacterial and the ability to produce toxicity in the cancer cells. This study aimed to evaluation of cytotoxic, antioxidant and antibacterial effects of zinc oxide nanoparticles synthesized by Amaranthus cruentus. Materials and Methods: This study was performed in vitro. The cytotoxic effects of biosynthesized ZnO nanoparticles were evaluated against the cancer cell line MDA-MB-231 and the normal cell line HUVEC by MTT assay. Also, antioxidant properties of these nanoparticles were evaluated by assays the DPPH and ABTS. Statistical analysis was performed by SPSS software and one way ANOVA. Antibacterial activity was also evaluated by the disc diffusion method on the gram-positive bacteria Staphylococcus aureus and gram-negative Pseudomonas aeruginosa. Results: The result of MTT assay showed that IC50 was about 32µg/ml in 48 hours after treatment of the breast cancer cells by nanoparticles while the viability of the normal cell line was 94% in the similar concentration of nanoparticles. The results of the antioxidant test showed that nanoparticles at a concentration of 1000µg/ml were able to inhibit 50% of ABTS free radicals, but they exhibited a slight potential for DPPH free radicals inhibition. Also, they had an inhibitory effect on Staphylococcus aureus and Pseudomonas aeruginosa growth. Conclusion: The results showed that ZnO nanoparticles biosynthesized by Amaranthus cruentus can have antioxidant, antibacterial and anti- cancer activities. zinc oxide nanoparticle antioxidant antibacterial anticancer amaranthus cruentus. Medicine (General) Neamati A verfasserin aut Yousefi-Rad H verfasserin aut In Fiyz̤ Kashan University of Medical Sciences and Health Services, 2017 24(2020), 2, Seite 133-141 (DE-627)669056162 (DE-600)2629607-X 20089821 nnns volume:24 year:2020 number:2 pages:133-141 https://doaj.org/article/3322f9f569794bcaab2730a102b45479 kostenfrei http://feyz.kaums.ac.ir/article-1-3877-en.html kostenfrei https://doaj.org/toc/1029-7855 Journal toc kostenfrei https://doaj.org/toc/2008-9821 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA AR 24 2020 2 133-141 |
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(DE-627)DOAJ045035857 (DE-599)DOAJ3322f9f569794bcaab2730a102b45479 DE-627 ger DE-627 rakwb per R5-920 Behjati-Moghaddam M verfasserin aut Evaluation of antioxidant, antibacterial and anticancer effects of the Zinc oxide nanoparticles biosynthesized by Amaranthus cruentus L. 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Nanoparticles are effective in treating the cancer disease due to their antioxidant, Antibacterial and the ability to produce toxicity in the cancer cells. This study aimed to evaluation of cytotoxic, antioxidant and antibacterial effects of zinc oxide nanoparticles synthesized by Amaranthus cruentus. Materials and Methods: This study was performed in vitro. The cytotoxic effects of biosynthesized ZnO nanoparticles were evaluated against the cancer cell line MDA-MB-231 and the normal cell line HUVEC by MTT assay. Also, antioxidant properties of these nanoparticles were evaluated by assays the DPPH and ABTS. Statistical analysis was performed by SPSS software and one way ANOVA. Antibacterial activity was also evaluated by the disc diffusion method on the gram-positive bacteria Staphylococcus aureus and gram-negative Pseudomonas aeruginosa. Results: The result of MTT assay showed that IC50 was about 32µg/ml in 48 hours after treatment of the breast cancer cells by nanoparticles while the viability of the normal cell line was 94% in the similar concentration of nanoparticles. The results of the antioxidant test showed that nanoparticles at a concentration of 1000µg/ml were able to inhibit 50% of ABTS free radicals, but they exhibited a slight potential for DPPH free radicals inhibition. Also, they had an inhibitory effect on Staphylococcus aureus and Pseudomonas aeruginosa growth. Conclusion: The results showed that ZnO nanoparticles biosynthesized by Amaranthus cruentus can have antioxidant, antibacterial and anti- cancer activities. zinc oxide nanoparticle antioxidant antibacterial anticancer amaranthus cruentus. Medicine (General) Neamati A verfasserin aut Yousefi-Rad H verfasserin aut In Fiyz̤ Kashan University of Medical Sciences and Health Services, 2017 24(2020), 2, Seite 133-141 (DE-627)669056162 (DE-600)2629607-X 20089821 nnns volume:24 year:2020 number:2 pages:133-141 https://doaj.org/article/3322f9f569794bcaab2730a102b45479 kostenfrei http://feyz.kaums.ac.ir/article-1-3877-en.html kostenfrei https://doaj.org/toc/1029-7855 Journal toc kostenfrei https://doaj.org/toc/2008-9821 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA AR 24 2020 2 133-141 |
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(DE-627)DOAJ045035857 (DE-599)DOAJ3322f9f569794bcaab2730a102b45479 DE-627 ger DE-627 rakwb per R5-920 Behjati-Moghaddam M verfasserin aut Evaluation of antioxidant, antibacterial and anticancer effects of the Zinc oxide nanoparticles biosynthesized by Amaranthus cruentus L. 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Nanoparticles are effective in treating the cancer disease due to their antioxidant, Antibacterial and the ability to produce toxicity in the cancer cells. This study aimed to evaluation of cytotoxic, antioxidant and antibacterial effects of zinc oxide nanoparticles synthesized by Amaranthus cruentus. Materials and Methods: This study was performed in vitro. The cytotoxic effects of biosynthesized ZnO nanoparticles were evaluated against the cancer cell line MDA-MB-231 and the normal cell line HUVEC by MTT assay. Also, antioxidant properties of these nanoparticles were evaluated by assays the DPPH and ABTS. Statistical analysis was performed by SPSS software and one way ANOVA. Antibacterial activity was also evaluated by the disc diffusion method on the gram-positive bacteria Staphylococcus aureus and gram-negative Pseudomonas aeruginosa. Results: The result of MTT assay showed that IC50 was about 32µg/ml in 48 hours after treatment of the breast cancer cells by nanoparticles while the viability of the normal cell line was 94% in the similar concentration of nanoparticles. The results of the antioxidant test showed that nanoparticles at a concentration of 1000µg/ml were able to inhibit 50% of ABTS free radicals, but they exhibited a slight potential for DPPH free radicals inhibition. Also, they had an inhibitory effect on Staphylococcus aureus and Pseudomonas aeruginosa growth. Conclusion: The results showed that ZnO nanoparticles biosynthesized by Amaranthus cruentus can have antioxidant, antibacterial and anti- cancer activities. zinc oxide nanoparticle antioxidant antibacterial anticancer amaranthus cruentus. Medicine (General) Neamati A verfasserin aut Yousefi-Rad H verfasserin aut In Fiyz̤ Kashan University of Medical Sciences and Health Services, 2017 24(2020), 2, Seite 133-141 (DE-627)669056162 (DE-600)2629607-X 20089821 nnns volume:24 year:2020 number:2 pages:133-141 https://doaj.org/article/3322f9f569794bcaab2730a102b45479 kostenfrei http://feyz.kaums.ac.ir/article-1-3877-en.html kostenfrei https://doaj.org/toc/1029-7855 Journal toc kostenfrei https://doaj.org/toc/2008-9821 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA AR 24 2020 2 133-141 |
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(DE-627)DOAJ045035857 (DE-599)DOAJ3322f9f569794bcaab2730a102b45479 DE-627 ger DE-627 rakwb per R5-920 Behjati-Moghaddam M verfasserin aut Evaluation of antioxidant, antibacterial and anticancer effects of the Zinc oxide nanoparticles biosynthesized by Amaranthus cruentus L. 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Nanoparticles are effective in treating the cancer disease due to their antioxidant, Antibacterial and the ability to produce toxicity in the cancer cells. This study aimed to evaluation of cytotoxic, antioxidant and antibacterial effects of zinc oxide nanoparticles synthesized by Amaranthus cruentus. Materials and Methods: This study was performed in vitro. The cytotoxic effects of biosynthesized ZnO nanoparticles were evaluated against the cancer cell line MDA-MB-231 and the normal cell line HUVEC by MTT assay. Also, antioxidant properties of these nanoparticles were evaluated by assays the DPPH and ABTS. Statistical analysis was performed by SPSS software and one way ANOVA. Antibacterial activity was also evaluated by the disc diffusion method on the gram-positive bacteria Staphylococcus aureus and gram-negative Pseudomonas aeruginosa. Results: The result of MTT assay showed that IC50 was about 32µg/ml in 48 hours after treatment of the breast cancer cells by nanoparticles while the viability of the normal cell line was 94% in the similar concentration of nanoparticles. The results of the antioxidant test showed that nanoparticles at a concentration of 1000µg/ml were able to inhibit 50% of ABTS free radicals, but they exhibited a slight potential for DPPH free radicals inhibition. Also, they had an inhibitory effect on Staphylococcus aureus and Pseudomonas aeruginosa growth. Conclusion: The results showed that ZnO nanoparticles biosynthesized by Amaranthus cruentus can have antioxidant, antibacterial and anti- cancer activities. zinc oxide nanoparticle antioxidant antibacterial anticancer amaranthus cruentus. Medicine (General) Neamati A verfasserin aut Yousefi-Rad H verfasserin aut In Fiyz̤ Kashan University of Medical Sciences and Health Services, 2017 24(2020), 2, Seite 133-141 (DE-627)669056162 (DE-600)2629607-X 20089821 nnns volume:24 year:2020 number:2 pages:133-141 https://doaj.org/article/3322f9f569794bcaab2730a102b45479 kostenfrei http://feyz.kaums.ac.ir/article-1-3877-en.html kostenfrei https://doaj.org/toc/1029-7855 Journal toc kostenfrei https://doaj.org/toc/2008-9821 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA AR 24 2020 2 133-141 |
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(DE-627)DOAJ045035857 (DE-599)DOAJ3322f9f569794bcaab2730a102b45479 DE-627 ger DE-627 rakwb per R5-920 Behjati-Moghaddam M verfasserin aut Evaluation of antioxidant, antibacterial and anticancer effects of the Zinc oxide nanoparticles biosynthesized by Amaranthus cruentus L. 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Nanoparticles are effective in treating the cancer disease due to their antioxidant, Antibacterial and the ability to produce toxicity in the cancer cells. This study aimed to evaluation of cytotoxic, antioxidant and antibacterial effects of zinc oxide nanoparticles synthesized by Amaranthus cruentus. Materials and Methods: This study was performed in vitro. The cytotoxic effects of biosynthesized ZnO nanoparticles were evaluated against the cancer cell line MDA-MB-231 and the normal cell line HUVEC by MTT assay. Also, antioxidant properties of these nanoparticles were evaluated by assays the DPPH and ABTS. Statistical analysis was performed by SPSS software and one way ANOVA. Antibacterial activity was also evaluated by the disc diffusion method on the gram-positive bacteria Staphylococcus aureus and gram-negative Pseudomonas aeruginosa. Results: The result of MTT assay showed that IC50 was about 32µg/ml in 48 hours after treatment of the breast cancer cells by nanoparticles while the viability of the normal cell line was 94% in the similar concentration of nanoparticles. The results of the antioxidant test showed that nanoparticles at a concentration of 1000µg/ml were able to inhibit 50% of ABTS free radicals, but they exhibited a slight potential for DPPH free radicals inhibition. Also, they had an inhibitory effect on Staphylococcus aureus and Pseudomonas aeruginosa growth. Conclusion: The results showed that ZnO nanoparticles biosynthesized by Amaranthus cruentus can have antioxidant, antibacterial and anti- cancer activities. zinc oxide nanoparticle antioxidant antibacterial anticancer amaranthus cruentus. Medicine (General) Neamati A verfasserin aut Yousefi-Rad H verfasserin aut In Fiyz̤ Kashan University of Medical Sciences and Health Services, 2017 24(2020), 2, Seite 133-141 (DE-627)669056162 (DE-600)2629607-X 20089821 nnns volume:24 year:2020 number:2 pages:133-141 https://doaj.org/article/3322f9f569794bcaab2730a102b45479 kostenfrei http://feyz.kaums.ac.ir/article-1-3877-en.html kostenfrei https://doaj.org/toc/1029-7855 Journal toc kostenfrei https://doaj.org/toc/2008-9821 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA AR 24 2020 2 133-141 |
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evaluation of antioxidant, antibacterial and anticancer effects of the zinc oxide nanoparticles biosynthesized by amaranthus cruentus l. |
| callnumber |
R5-920 |
| title_auth |
Evaluation of antioxidant, antibacterial and anticancer effects of the Zinc oxide nanoparticles biosynthesized by Amaranthus cruentus L. |
| abstract |
Background: Nanoparticles are effective in treating the cancer disease due to their antioxidant, Antibacterial and the ability to produce toxicity in the cancer cells. This study aimed to evaluation of cytotoxic, antioxidant and antibacterial effects of zinc oxide nanoparticles synthesized by Amaranthus cruentus. Materials and Methods: This study was performed in vitro. The cytotoxic effects of biosynthesized ZnO nanoparticles were evaluated against the cancer cell line MDA-MB-231 and the normal cell line HUVEC by MTT assay. Also, antioxidant properties of these nanoparticles were evaluated by assays the DPPH and ABTS. Statistical analysis was performed by SPSS software and one way ANOVA. Antibacterial activity was also evaluated by the disc diffusion method on the gram-positive bacteria Staphylococcus aureus and gram-negative Pseudomonas aeruginosa. Results: The result of MTT assay showed that IC50 was about 32µg/ml in 48 hours after treatment of the breast cancer cells by nanoparticles while the viability of the normal cell line was 94% in the similar concentration of nanoparticles. The results of the antioxidant test showed that nanoparticles at a concentration of 1000µg/ml were able to inhibit 50% of ABTS free radicals, but they exhibited a slight potential for DPPH free radicals inhibition. Also, they had an inhibitory effect on Staphylococcus aureus and Pseudomonas aeruginosa growth. Conclusion: The results showed that ZnO nanoparticles biosynthesized by Amaranthus cruentus can have antioxidant, antibacterial and anti- cancer activities. |
| abstractGer |
Background: Nanoparticles are effective in treating the cancer disease due to their antioxidant, Antibacterial and the ability to produce toxicity in the cancer cells. This study aimed to evaluation of cytotoxic, antioxidant and antibacterial effects of zinc oxide nanoparticles synthesized by Amaranthus cruentus. Materials and Methods: This study was performed in vitro. The cytotoxic effects of biosynthesized ZnO nanoparticles were evaluated against the cancer cell line MDA-MB-231 and the normal cell line HUVEC by MTT assay. Also, antioxidant properties of these nanoparticles were evaluated by assays the DPPH and ABTS. Statistical analysis was performed by SPSS software and one way ANOVA. Antibacterial activity was also evaluated by the disc diffusion method on the gram-positive bacteria Staphylococcus aureus and gram-negative Pseudomonas aeruginosa. Results: The result of MTT assay showed that IC50 was about 32µg/ml in 48 hours after treatment of the breast cancer cells by nanoparticles while the viability of the normal cell line was 94% in the similar concentration of nanoparticles. The results of the antioxidant test showed that nanoparticles at a concentration of 1000µg/ml were able to inhibit 50% of ABTS free radicals, but they exhibited a slight potential for DPPH free radicals inhibition. Also, they had an inhibitory effect on Staphylococcus aureus and Pseudomonas aeruginosa growth. Conclusion: The results showed that ZnO nanoparticles biosynthesized by Amaranthus cruentus can have antioxidant, antibacterial and anti- cancer activities. |
| abstract_unstemmed |
Background: Nanoparticles are effective in treating the cancer disease due to their antioxidant, Antibacterial and the ability to produce toxicity in the cancer cells. This study aimed to evaluation of cytotoxic, antioxidant and antibacterial effects of zinc oxide nanoparticles synthesized by Amaranthus cruentus. Materials and Methods: This study was performed in vitro. The cytotoxic effects of biosynthesized ZnO nanoparticles were evaluated against the cancer cell line MDA-MB-231 and the normal cell line HUVEC by MTT assay. Also, antioxidant properties of these nanoparticles were evaluated by assays the DPPH and ABTS. Statistical analysis was performed by SPSS software and one way ANOVA. Antibacterial activity was also evaluated by the disc diffusion method on the gram-positive bacteria Staphylococcus aureus and gram-negative Pseudomonas aeruginosa. Results: The result of MTT assay showed that IC50 was about 32µg/ml in 48 hours after treatment of the breast cancer cells by nanoparticles while the viability of the normal cell line was 94% in the similar concentration of nanoparticles. The results of the antioxidant test showed that nanoparticles at a concentration of 1000µg/ml were able to inhibit 50% of ABTS free radicals, but they exhibited a slight potential for DPPH free radicals inhibition. Also, they had an inhibitory effect on Staphylococcus aureus and Pseudomonas aeruginosa growth. Conclusion: The results showed that ZnO nanoparticles biosynthesized by Amaranthus cruentus can have antioxidant, antibacterial and anti- cancer activities. |
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| title_short |
Evaluation of antioxidant, antibacterial and anticancer effects of the Zinc oxide nanoparticles biosynthesized by Amaranthus cruentus L. |
| url |
https://doaj.org/article/3322f9f569794bcaab2730a102b45479 http://feyz.kaums.ac.ir/article-1-3877-en.html https://doaj.org/toc/1029-7855 https://doaj.org/toc/2008-9821 |
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true |
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Neamati A Yousefi-Rad H |
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Neamati A Yousefi-Rad H |
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669056162 |
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R - General Medicine |
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c |
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| up_date |
2024-07-04T01:24:52.454Z |
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