Study the efficacy of herbal formulation Niśāmalakī in animal model of polycystic ovarian disease syndrome

Polycystic ovarian syndrome (PCOS) is a complex endocrine disorder characterized by insulin resistance which in turn leads to elevated levels of androgens, anovulation, amenorrhea or oligomenorrhea, obesity and polycystic ovaries. Objectives: To evaluate efficacy of herbal formulations-Nishamalaki a...
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Autor*in:	Jayshree S Dawane [verfasserIn] Vijaya Pandit [verfasserIn] Kapil S Khade [verfasserIn] Sonali P Suryawanshi [verfasserIn] Asmita Wele [verfasserIn] Madhuri Pawar [verfasserIn] Supriya Bhalerao [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2017

Schlagwörter:	Androgens follicular stimulating hormone insulin luteinizing hormone oestrus cycle

Übergeordnetes Werk:	In: Ancient Science of Life - Wolters Kluwer Medknow Publications, 2013, 37(2017), 2, Seite 86-93
Übergeordnetes Werk:	volume:37 ; year:2017 ; number:2 ; pages:86-93

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.4103/asl.ASL_51_18

Katalog-ID:	DOAJ045815739

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520			\|a Polycystic ovarian syndrome (PCOS) is a complex endocrine disorder characterized by insulin resistance which in turn leads to elevated levels of androgens, anovulation, amenorrhea or oligomenorrhea, obesity and polycystic ovaries. Objectives: To evaluate efficacy of herbal formulations-Nishamalaki and Kanchanar Guggulu in animal model of PCOS. Material and Methods: Six female rats of Group I served as control (No Letrozole, no treatment), Letrozole was given 1mg/kg /day for 28 days to induce PCOS in remaining female wistar rats which were then divided into 6 groups of 6 animals each Group II- PCOS disease control, Group III – Clomiphene citrate, Group IV- Nishamalaki, Group V- Metformin, Group VI- Nishamalaki & Metformin and Group VII- Kanchanar Guggulu. Animals were treated orally according to groups for 56 days. Body weight, food intake, Insulin, blood glucose levels and lipid profile checked before and after treatment. Vaginal smear was done daily to study estrous changes. Results: Along with dyslipidaemia, Rats with PCOS showed increase in body weight and insulin levels. Significant reduction in body weight, lipid profile, Blood sugar and insulin was seen in Nishamalaki treated animals but not in Kanchanar Guggulu group. Kanchanar Guggulu and Nishamalaki regularized the cycles in 1st and 3rd weeks respectively. Conclusion: Nishamalaki effectively corrected all changes in PCOS whereas Kanchanar Guggulu only regularized the estrous cycles.
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spelling	10.4103/asl.ASL_51_18 doi (DE-627)DOAJ045815739 (DE-599)DOAJ62a7eaa972f04cddb1300c696a6c1500 DE-627 ger DE-627 rakwb eng Jayshree S Dawane verfasserin aut Study the efficacy of herbal formulation Niśāmalakī in animal model of polycystic ovarian disease syndrome 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Polycystic ovarian syndrome (PCOS) is a complex endocrine disorder characterized by insulin resistance which in turn leads to elevated levels of androgens, anovulation, amenorrhea or oligomenorrhea, obesity and polycystic ovaries. Objectives: To evaluate efficacy of herbal formulations-Nishamalaki and Kanchanar Guggulu in animal model of PCOS. Material and Methods: Six female rats of Group I served as control (No Letrozole, no treatment), Letrozole was given 1mg/kg /day for 28 days to induce PCOS in remaining female wistar rats which were then divided into 6 groups of 6 animals each Group II- PCOS disease control, Group III – Clomiphene citrate, Group IV- Nishamalaki, Group V- Metformin, Group VI- Nishamalaki & Metformin and Group VII- Kanchanar Guggulu. Animals were treated orally according to groups for 56 days. Body weight, food intake, Insulin, blood glucose levels and lipid profile checked before and after treatment. Vaginal smear was done daily to study estrous changes. Results: Along with dyslipidaemia, Rats with PCOS showed increase in body weight and insulin levels. Significant reduction in body weight, lipid profile, Blood sugar and insulin was seen in Nishamalaki treated animals but not in Kanchanar Guggulu group. Kanchanar Guggulu and Nishamalaki regularized the cycles in 1st and 3rd weeks respectively. Conclusion: Nishamalaki effectively corrected all changes in PCOS whereas Kanchanar Guggulu only regularized the estrous cycles. Androgens follicular stimulating hormone insulin luteinizing hormone oestrus cycle Medicine R Vijaya Pandit verfasserin aut Kapil S Khade verfasserin aut Sonali P Suryawanshi verfasserin aut Asmita Wele verfasserin aut Madhuri Pawar verfasserin aut Supriya Bhalerao verfasserin aut In Ancient Science of Life Wolters Kluwer Medknow Publications, 2013 37(2017), 2, Seite 86-93 (DE-627)718606108 (DE-600)2660395-0 22499547 nnns volume:37 year:2017 number:2 pages:86-93 https://doi.org/10.4103/asl.ASL_51_18 kostenfrei https://doaj.org/article/62a7eaa972f04cddb1300c696a6c1500 kostenfrei http://www.ancientscienceoflife.org/article.asp?issn=0257-7941;year=2017;volume=37;issue=2;spage=86;epage=93;aulast=Dawane kostenfrei https://doaj.org/toc/0257-7941 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 37 2017 2 86-93
allfields_unstemmed	10.4103/asl.ASL_51_18 doi (DE-627)DOAJ045815739 (DE-599)DOAJ62a7eaa972f04cddb1300c696a6c1500 DE-627 ger DE-627 rakwb eng Jayshree S Dawane verfasserin aut Study the efficacy of herbal formulation Niśāmalakī in animal model of polycystic ovarian disease syndrome 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Polycystic ovarian syndrome (PCOS) is a complex endocrine disorder characterized by insulin resistance which in turn leads to elevated levels of androgens, anovulation, amenorrhea or oligomenorrhea, obesity and polycystic ovaries. Objectives: To evaluate efficacy of herbal formulations-Nishamalaki and Kanchanar Guggulu in animal model of PCOS. Material and Methods: Six female rats of Group I served as control (No Letrozole, no treatment), Letrozole was given 1mg/kg /day for 28 days to induce PCOS in remaining female wistar rats which were then divided into 6 groups of 6 animals each Group II- PCOS disease control, Group III – Clomiphene citrate, Group IV- Nishamalaki, Group V- Metformin, Group VI- Nishamalaki & Metformin and Group VII- Kanchanar Guggulu. Animals were treated orally according to groups for 56 days. Body weight, food intake, Insulin, blood glucose levels and lipid profile checked before and after treatment. Vaginal smear was done daily to study estrous changes. Results: Along with dyslipidaemia, Rats with PCOS showed increase in body weight and insulin levels. Significant reduction in body weight, lipid profile, Blood sugar and insulin was seen in Nishamalaki treated animals but not in Kanchanar Guggulu group. Kanchanar Guggulu and Nishamalaki regularized the cycles in 1st and 3rd weeks respectively. Conclusion: Nishamalaki effectively corrected all changes in PCOS whereas Kanchanar Guggulu only regularized the estrous cycles. Androgens follicular stimulating hormone insulin luteinizing hormone oestrus cycle Medicine R Vijaya Pandit verfasserin aut Kapil S Khade verfasserin aut Sonali P Suryawanshi verfasserin aut Asmita Wele verfasserin aut Madhuri Pawar verfasserin aut Supriya Bhalerao verfasserin aut In Ancient Science of Life Wolters Kluwer Medknow Publications, 2013 37(2017), 2, Seite 86-93 (DE-627)718606108 (DE-600)2660395-0 22499547 nnns volume:37 year:2017 number:2 pages:86-93 https://doi.org/10.4103/asl.ASL_51_18 kostenfrei https://doaj.org/article/62a7eaa972f04cddb1300c696a6c1500 kostenfrei http://www.ancientscienceoflife.org/article.asp?issn=0257-7941;year=2017;volume=37;issue=2;spage=86;epage=93;aulast=Dawane kostenfrei https://doaj.org/toc/0257-7941 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 37 2017 2 86-93
allfieldsGer	10.4103/asl.ASL_51_18 doi (DE-627)DOAJ045815739 (DE-599)DOAJ62a7eaa972f04cddb1300c696a6c1500 DE-627 ger DE-627 rakwb eng Jayshree S Dawane verfasserin aut Study the efficacy of herbal formulation Niśāmalakī in animal model of polycystic ovarian disease syndrome 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Polycystic ovarian syndrome (PCOS) is a complex endocrine disorder characterized by insulin resistance which in turn leads to elevated levels of androgens, anovulation, amenorrhea or oligomenorrhea, obesity and polycystic ovaries. Objectives: To evaluate efficacy of herbal formulations-Nishamalaki and Kanchanar Guggulu in animal model of PCOS. Material and Methods: Six female rats of Group I served as control (No Letrozole, no treatment), Letrozole was given 1mg/kg /day for 28 days to induce PCOS in remaining female wistar rats which were then divided into 6 groups of 6 animals each Group II- PCOS disease control, Group III – Clomiphene citrate, Group IV- Nishamalaki, Group V- Metformin, Group VI- Nishamalaki & Metformin and Group VII- Kanchanar Guggulu. Animals were treated orally according to groups for 56 days. Body weight, food intake, Insulin, blood glucose levels and lipid profile checked before and after treatment. Vaginal smear was done daily to study estrous changes. Results: Along with dyslipidaemia, Rats with PCOS showed increase in body weight and insulin levels. Significant reduction in body weight, lipid profile, Blood sugar and insulin was seen in Nishamalaki treated animals but not in Kanchanar Guggulu group. Kanchanar Guggulu and Nishamalaki regularized the cycles in 1st and 3rd weeks respectively. Conclusion: Nishamalaki effectively corrected all changes in PCOS whereas Kanchanar Guggulu only regularized the estrous cycles. Androgens follicular stimulating hormone insulin luteinizing hormone oestrus cycle Medicine R Vijaya Pandit verfasserin aut Kapil S Khade verfasserin aut Sonali P Suryawanshi verfasserin aut Asmita Wele verfasserin aut Madhuri Pawar verfasserin aut Supriya Bhalerao verfasserin aut In Ancient Science of Life Wolters Kluwer Medknow Publications, 2013 37(2017), 2, Seite 86-93 (DE-627)718606108 (DE-600)2660395-0 22499547 nnns volume:37 year:2017 number:2 pages:86-93 https://doi.org/10.4103/asl.ASL_51_18 kostenfrei https://doaj.org/article/62a7eaa972f04cddb1300c696a6c1500 kostenfrei http://www.ancientscienceoflife.org/article.asp?issn=0257-7941;year=2017;volume=37;issue=2;spage=86;epage=93;aulast=Dawane kostenfrei https://doaj.org/toc/0257-7941 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 37 2017 2 86-93
allfieldsSound	10.4103/asl.ASL_51_18 doi (DE-627)DOAJ045815739 (DE-599)DOAJ62a7eaa972f04cddb1300c696a6c1500 DE-627 ger DE-627 rakwb eng Jayshree S Dawane verfasserin aut Study the efficacy of herbal formulation Niśāmalakī in animal model of polycystic ovarian disease syndrome 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Polycystic ovarian syndrome (PCOS) is a complex endocrine disorder characterized by insulin resistance which in turn leads to elevated levels of androgens, anovulation, amenorrhea or oligomenorrhea, obesity and polycystic ovaries. Objectives: To evaluate efficacy of herbal formulations-Nishamalaki and Kanchanar Guggulu in animal model of PCOS. Material and Methods: Six female rats of Group I served as control (No Letrozole, no treatment), Letrozole was given 1mg/kg /day for 28 days to induce PCOS in remaining female wistar rats which were then divided into 6 groups of 6 animals each Group II- PCOS disease control, Group III – Clomiphene citrate, Group IV- Nishamalaki, Group V- Metformin, Group VI- Nishamalaki & Metformin and Group VII- Kanchanar Guggulu. Animals were treated orally according to groups for 56 days. Body weight, food intake, Insulin, blood glucose levels and lipid profile checked before and after treatment. Vaginal smear was done daily to study estrous changes. Results: Along with dyslipidaemia, Rats with PCOS showed increase in body weight and insulin levels. Significant reduction in body weight, lipid profile, Blood sugar and insulin was seen in Nishamalaki treated animals but not in Kanchanar Guggulu group. Kanchanar Guggulu and Nishamalaki regularized the cycles in 1st and 3rd weeks respectively. Conclusion: Nishamalaki effectively corrected all changes in PCOS whereas Kanchanar Guggulu only regularized the estrous cycles. Androgens follicular stimulating hormone insulin luteinizing hormone oestrus cycle Medicine R Vijaya Pandit verfasserin aut Kapil S Khade verfasserin aut Sonali P Suryawanshi verfasserin aut Asmita Wele verfasserin aut Madhuri Pawar verfasserin aut Supriya Bhalerao verfasserin aut In Ancient Science of Life Wolters Kluwer Medknow Publications, 2013 37(2017), 2, Seite 86-93 (DE-627)718606108 (DE-600)2660395-0 22499547 nnns volume:37 year:2017 number:2 pages:86-93 https://doi.org/10.4103/asl.ASL_51_18 kostenfrei https://doaj.org/article/62a7eaa972f04cddb1300c696a6c1500 kostenfrei http://www.ancientscienceoflife.org/article.asp?issn=0257-7941;year=2017;volume=37;issue=2;spage=86;epage=93;aulast=Dawane kostenfrei https://doaj.org/toc/0257-7941 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 37 2017 2 86-93
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authorswithroles_txt_mv	Jayshree S Dawane @@aut@@ Vijaya Pandit @@aut@@ Kapil S Khade @@aut@@ Sonali P Suryawanshi @@aut@@ Asmita Wele @@aut@@ Madhuri Pawar @@aut@@ Supriya Bhalerao @@aut@@
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author	Jayshree S Dawane
spellingShingle	Jayshree S Dawane misc Androgens misc follicular stimulating hormone misc insulin misc luteinizing hormone misc oestrus cycle misc Medicine misc R Study the efficacy of herbal formulation Niśāmalakī in animal model of polycystic ovarian disease syndrome
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topic_title	Study the efficacy of herbal formulation Niśāmalakī in animal model of polycystic ovarian disease syndrome Androgens follicular stimulating hormone insulin luteinizing hormone oestrus cycle
topic	misc Androgens misc follicular stimulating hormone misc insulin misc luteinizing hormone misc oestrus cycle misc Medicine misc R
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title	Study the efficacy of herbal formulation Niśāmalakī in animal model of polycystic ovarian disease syndrome
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title_full	Study the efficacy of herbal formulation Niśāmalakī in animal model of polycystic ovarian disease syndrome
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title_sort	study the efficacy of herbal formulation niśāmalakī in animal model of polycystic ovarian disease syndrome
title_auth	Study the efficacy of herbal formulation Niśāmalakī in animal model of polycystic ovarian disease syndrome
abstract	Polycystic ovarian syndrome (PCOS) is a complex endocrine disorder characterized by insulin resistance which in turn leads to elevated levels of androgens, anovulation, amenorrhea or oligomenorrhea, obesity and polycystic ovaries. Objectives: To evaluate efficacy of herbal formulations-Nishamalaki and Kanchanar Guggulu in animal model of PCOS. Material and Methods: Six female rats of Group I served as control (No Letrozole, no treatment), Letrozole was given 1mg/kg /day for 28 days to induce PCOS in remaining female wistar rats which were then divided into 6 groups of 6 animals each Group II- PCOS disease control, Group III – Clomiphene citrate, Group IV- Nishamalaki, Group V- Metformin, Group VI- Nishamalaki & Metformin and Group VII- Kanchanar Guggulu. Animals were treated orally according to groups for 56 days. Body weight, food intake, Insulin, blood glucose levels and lipid profile checked before and after treatment. Vaginal smear was done daily to study estrous changes. Results: Along with dyslipidaemia, Rats with PCOS showed increase in body weight and insulin levels. Significant reduction in body weight, lipid profile, Blood sugar and insulin was seen in Nishamalaki treated animals but not in Kanchanar Guggulu group. Kanchanar Guggulu and Nishamalaki regularized the cycles in 1st and 3rd weeks respectively. Conclusion: Nishamalaki effectively corrected all changes in PCOS whereas Kanchanar Guggulu only regularized the estrous cycles.
abstractGer	Polycystic ovarian syndrome (PCOS) is a complex endocrine disorder characterized by insulin resistance which in turn leads to elevated levels of androgens, anovulation, amenorrhea or oligomenorrhea, obesity and polycystic ovaries. Objectives: To evaluate efficacy of herbal formulations-Nishamalaki and Kanchanar Guggulu in animal model of PCOS. Material and Methods: Six female rats of Group I served as control (No Letrozole, no treatment), Letrozole was given 1mg/kg /day for 28 days to induce PCOS in remaining female wistar rats which were then divided into 6 groups of 6 animals each Group II- PCOS disease control, Group III – Clomiphene citrate, Group IV- Nishamalaki, Group V- Metformin, Group VI- Nishamalaki & Metformin and Group VII- Kanchanar Guggulu. Animals were treated orally according to groups for 56 days. Body weight, food intake, Insulin, blood glucose levels and lipid profile checked before and after treatment. Vaginal smear was done daily to study estrous changes. Results: Along with dyslipidaemia, Rats with PCOS showed increase in body weight and insulin levels. Significant reduction in body weight, lipid profile, Blood sugar and insulin was seen in Nishamalaki treated animals but not in Kanchanar Guggulu group. Kanchanar Guggulu and Nishamalaki regularized the cycles in 1st and 3rd weeks respectively. Conclusion: Nishamalaki effectively corrected all changes in PCOS whereas Kanchanar Guggulu only regularized the estrous cycles.
abstract_unstemmed	Polycystic ovarian syndrome (PCOS) is a complex endocrine disorder characterized by insulin resistance which in turn leads to elevated levels of androgens, anovulation, amenorrhea or oligomenorrhea, obesity and polycystic ovaries. Objectives: To evaluate efficacy of herbal formulations-Nishamalaki and Kanchanar Guggulu in animal model of PCOS. Material and Methods: Six female rats of Group I served as control (No Letrozole, no treatment), Letrozole was given 1mg/kg /day for 28 days to induce PCOS in remaining female wistar rats which were then divided into 6 groups of 6 animals each Group II- PCOS disease control, Group III – Clomiphene citrate, Group IV- Nishamalaki, Group V- Metformin, Group VI- Nishamalaki & Metformin and Group VII- Kanchanar Guggulu. Animals were treated orally according to groups for 56 days. Body weight, food intake, Insulin, blood glucose levels and lipid profile checked before and after treatment. Vaginal smear was done daily to study estrous changes. Results: Along with dyslipidaemia, Rats with PCOS showed increase in body weight and insulin levels. Significant reduction in body weight, lipid profile, Blood sugar and insulin was seen in Nishamalaki treated animals but not in Kanchanar Guggulu group. Kanchanar Guggulu and Nishamalaki regularized the cycles in 1st and 3rd weeks respectively. Conclusion: Nishamalaki effectively corrected all changes in PCOS whereas Kanchanar Guggulu only regularized the estrous cycles.
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title_short	Study the efficacy of herbal formulation Niśāmalakī in animal model of polycystic ovarian disease syndrome
url	https://doi.org/10.4103/asl.ASL_51_18 https://doaj.org/article/62a7eaa972f04cddb1300c696a6c1500 http://www.ancientscienceoflife.org/article.asp?issn=0257-7941;year=2017;volume=37;issue=2;spage=86;epage=93;aulast=Dawane https://doaj.org/toc/0257-7941
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Significant reduction in body weight, lipid profile, Blood sugar and insulin was seen in Nishamalaki treated animals but not in Kanchanar Guggulu group. Kanchanar Guggulu and Nishamalaki regularized the cycles in 1st and 3rd weeks respectively. 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Study the efficacy of herbal formulation Niśāmalakī in animal model of polycystic ovarian disease syndrome

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