Hemorheological properties in patients with type-1 and type-2 diabetes mellitus

The hemorheologic disorders, which are potentially deleterious in a wide range of pathologies, were studied in patients with type-1 and type-2 diabetes mellitus. The significant determinants of blood viscosity, red blood cells (RBC) deformability and RBC reversible aggregation were assessed by ektac...
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Autor*in:	Irina A. Sokolova [verfasserIn] Aleksandrina V. Kachalova [verfasserIn] Anastasiya A. Fabrichnova [verfasserIn] Yulia A. Kovaleva [verfasserIn] Aleksandr A. Shahnazarov [verfasserIn] Vladimir B. Koshelev [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2017

Schlagwörter:	diabetes mellitus RBC aggregation RBC deformability monafram

Übergeordnetes Werk:	In: Journal of Biomedical Photonics & Engineering - Samara National Research University, 2018, 3(2017), 3
Übergeordnetes Werk:	volume:3 ; year:2017 ; number:3

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.18287/JBPE17.03.030402

Katalog-ID:	DOAJ045932220

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allfieldsSound	10.18287/JBPE17.03.030402 doi (DE-627)DOAJ045932220 (DE-599)DOAJf25846fbe0374849997c016c28aabdc8 DE-627 ger DE-627 rakwb eng TA1501-1820 R855-855.5 Irina A. Sokolova verfasserin aut Hemorheological properties in patients with type-1 and type-2 diabetes mellitus 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The hemorheologic disorders, which are potentially deleterious in a wide range of pathologies, were studied in patients with type-1 and type-2 diabetes mellitus. The significant determinants of blood viscosity, red blood cells (RBC) deformability and RBC reversible aggregation were assessed by ektacytometry and by laser backscattering technique, respectively. For both types of the disease, we observed acceleration of the first phase of RBC aggregation that contrasted with its deceleration at the second phase. The hydrodynamic stability of the aggregates, especially the smallest ones, exceeded the normal values in both cases. The influence of GP IIb/IIIa receptor inhibitor, monafram on RBC aggregation and disaggregation was the same in the cases of patients and normal subjects. The maximal shear induced RBC stretching exceeded the normal one in patients of both groups. The data reveal not only pathological but also compensatory character of hemorheological alterations in patients with type-1 and type-2 diabetes mellitus. diabetes mellitus RBC aggregation RBC deformability monafram Applied optics. Photonics Medical technology Aleksandrina V. Kachalova verfasserin aut Anastasiya A. Fabrichnova verfasserin aut Yulia A. Kovaleva verfasserin aut Aleksandr A. Shahnazarov verfasserin aut Vladimir B. Koshelev verfasserin aut In Journal of Biomedical Photonics & Engineering Samara National Research University, 2018 3(2017), 3 (DE-627)1005305714 24112844 nnns volume:3 year:2017 number:3 https://doi.org/10.18287/JBPE17.03.030402 kostenfrei https://doaj.org/article/f25846fbe0374849997c016c28aabdc8 kostenfrei http://jbpe.ssau.ru/index.php/JBPE/article/view/3219 kostenfrei https://doaj.org/toc/2411-2844 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 3 2017 3
language	English
source	In Journal of Biomedical Photonics & Engineering 3(2017), 3 volume:3 year:2017 number:3
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institution	findex.gbv.de
topic_facet	diabetes mellitus RBC aggregation RBC deformability monafram Applied optics. Photonics Medical technology
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container_title	Journal of Biomedical Photonics & Engineering
authorswithroles_txt_mv	Irina A. Sokolova @@aut@@ Aleksandrina V. Kachalova @@aut@@ Anastasiya A. Fabrichnova @@aut@@ Yulia A. Kovaleva @@aut@@ Aleksandr A. Shahnazarov @@aut@@ Vladimir B. Koshelev @@aut@@
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callnumber-first	T - Technology
author	Irina A. Sokolova
spellingShingle	Irina A. Sokolova misc TA1501-1820 misc R855-855.5 misc diabetes mellitus misc RBC aggregation misc RBC deformability misc monafram misc Applied optics. Photonics misc Medical technology Hemorheological properties in patients with type-1 and type-2 diabetes mellitus
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topic_title	TA1501-1820 R855-855.5 Hemorheological properties in patients with type-1 and type-2 diabetes mellitus diabetes mellitus RBC aggregation RBC deformability monafram
topic	misc TA1501-1820 misc R855-855.5 misc diabetes mellitus misc RBC aggregation misc RBC deformability misc monafram misc Applied optics. Photonics misc Medical technology
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title	Hemorheological properties in patients with type-1 and type-2 diabetes mellitus
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title_full	Hemorheological properties in patients with type-1 and type-2 diabetes mellitus
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title_sort	hemorheological properties in patients with type-1 and type-2 diabetes mellitus
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title_auth	Hemorheological properties in patients with type-1 and type-2 diabetes mellitus
abstract	The hemorheologic disorders, which are potentially deleterious in a wide range of pathologies, were studied in patients with type-1 and type-2 diabetes mellitus. The significant determinants of blood viscosity, red blood cells (RBC) deformability and RBC reversible aggregation were assessed by ektacytometry and by laser backscattering technique, respectively. For both types of the disease, we observed acceleration of the first phase of RBC aggregation that contrasted with its deceleration at the second phase. The hydrodynamic stability of the aggregates, especially the smallest ones, exceeded the normal values in both cases. The influence of GP IIb/IIIa receptor inhibitor, monafram on RBC aggregation and disaggregation was the same in the cases of patients and normal subjects. The maximal shear induced RBC stretching exceeded the normal one in patients of both groups. The data reveal not only pathological but also compensatory character of hemorheological alterations in patients with type-1 and type-2 diabetes mellitus.
abstractGer	The hemorheologic disorders, which are potentially deleterious in a wide range of pathologies, were studied in patients with type-1 and type-2 diabetes mellitus. The significant determinants of blood viscosity, red blood cells (RBC) deformability and RBC reversible aggregation were assessed by ektacytometry and by laser backscattering technique, respectively. For both types of the disease, we observed acceleration of the first phase of RBC aggregation that contrasted with its deceleration at the second phase. The hydrodynamic stability of the aggregates, especially the smallest ones, exceeded the normal values in both cases. The influence of GP IIb/IIIa receptor inhibitor, monafram on RBC aggregation and disaggregation was the same in the cases of patients and normal subjects. The maximal shear induced RBC stretching exceeded the normal one in patients of both groups. The data reveal not only pathological but also compensatory character of hemorheological alterations in patients with type-1 and type-2 diabetes mellitus.
abstract_unstemmed	The hemorheologic disorders, which are potentially deleterious in a wide range of pathologies, were studied in patients with type-1 and type-2 diabetes mellitus. The significant determinants of blood viscosity, red blood cells (RBC) deformability and RBC reversible aggregation were assessed by ektacytometry and by laser backscattering technique, respectively. For both types of the disease, we observed acceleration of the first phase of RBC aggregation that contrasted with its deceleration at the second phase. The hydrodynamic stability of the aggregates, especially the smallest ones, exceeded the normal values in both cases. The influence of GP IIb/IIIa receptor inhibitor, monafram on RBC aggregation and disaggregation was the same in the cases of patients and normal subjects. The maximal shear induced RBC stretching exceeded the normal one in patients of both groups. The data reveal not only pathological but also compensatory character of hemorheological alterations in patients with type-1 and type-2 diabetes mellitus.
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title_short	Hemorheological properties in patients with type-1 and type-2 diabetes mellitus
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Hemorheological properties in patients with type-1 and type-2 diabetes mellitus

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