A Revolution of Biomaterials in Medical Sciences

Biomaterial science discusses diagnostics and therapeutics; it encloses the basic sciences (Chemistry, Physics, Biology, and Mathematics), medical sciences, and engineering sciences. The Biomaterials field has noticed a revolutionary growth since the application of old medical devices used in the late 1940s and early 1050s.1 This field progressed with the industrial revolution, increasing population, advances in medical health, luxurious life standards, and previously untreatable medical conditions that caused dire health crises to humanity. Right after World War II, the scientists started working on the biomaterials by dint off. Biomedicals experienced a revolutionary generation with an average gap of 10-20 years approximately. The first-generation biomaterials era is supposed to be between the 1950s–1960s. These materials were mainly used for industrial purposes rather than being specifically used for medical purposes. They were merely the conjugation of physical properties particular to use in the clinical field and also because they were bioinert, that is why they thought to be biocompatible.2 The extensively used silicone rubbers and elastomeric polymers were prototypical. Pyrolytic carbon was synthesized in the early 1960s as a material used for fuel-related components like fuel particles. But today, it is widely used to coat the mechanical heart valves, they are considered to be the earliest biomaterials whose properties and composition were analyzed thoroughly by using the principles of engineering.3 The second-generation biomaterials are evolved from previous biomaterials that were designed to show a therapeutic effect after being implanted in human tissues. In the 1980s these biomaterials were extensively used in dental, orthopedic, ocular surgeries. In the controlled localized drugs release applications like Norplant hormone-loaded contraceptive formulations, and in other devices like HeartMate, a device that is used to assist left ventricle in patients who have congestive heart failure. This aforementioned device is internally composed of Polyurethane, a material that controls a thrombotic pathology to reduce the risk of de-adhering fractions of blood clots into the bloodstream of patients. Drug-eluting endovascular stents is another exemplary precedent of the second-generation biomaterials used in medical devices that helps in controlling the restenosis following balloon angioplasty.4,5 The third and the most revolutionary generation of biomaterials elicits the novel art of science and technology, that are bestowed with the goal of regeneration of functional human tissues. Throughout the medical history of humans, medical scientists, physicians were unable to restore and regenerate the infected tissues and organs of humans. The role of the physician was very palliative – relieving symptoms without curing. The boom in regenerative medicine and tissue engineering broke all previous stereotypes by replacing the infected tissues and organs with implants. As we can see now these both medical domains are widely being used in therapeutics. The term tissue engineering is a broad concept that inter-relates the biomedical, engineering, medical sciences principles simultaneously.6 The advances in hip joint prosthesis are another precedent of the third generation of biomaterials, they are fabricated from a plethora of materials like titanium, composites, ceramics, Ultrahigh molecular weight polyethylene, and special high strength alloys. The contemporary Intraocular lenses which are made from a biopolymer named Polymethyl methacrylate have also played a tremendous role in treating and correcting vision problems, Per-Ingvar Branemark revolutionized the dental implantology by introducing the development of roots from titanium, an applaudable use of Polyethylene terephthalate and Polytetrafluoroethylene in dialysis machine also helped medical practitioners in treating kidneys diseases, the suturing techniques uses biomaterials mainly Polyglactin, Polypropylene, Polydioxanone, etc. also helping the surgeons in vascular and skin grafting of patients and the list does not end here. Almost everything that we use in our daily life is the contemporary blessings of biomaterials.7 Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Taimoor Hassan [verfasserIn] Sana Saeed [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2021

Schlagwörter:	Biomaterials, Prosthesis, generations of biomaterials, polymers

Übergeordnetes Werk:	In: Journal of Rawalpindi Medical College - Rawalpindi Medical University, 2020, 25(2021), 3
Übergeordnetes Werk:	volume:25 ; year:2021 ; number:3

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.37939/jrmc.v25i3.1649

Katalog-ID:	DOAJ046142215

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allfields	10.37939/jrmc.v25i3.1649 doi (DE-627)DOAJ046142215 (DE-599)DOAJ448224d893cd44debea327a89767f3ba DE-627 ger DE-627 rakwb eng Taimoor Hassan verfasserin aut A Revolution of Biomaterials in Medical Sciences 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Biomaterial science discusses diagnostics and therapeutics; it encloses the basic sciences (Chemistry, Physics, Biology, and Mathematics), medical sciences, and engineering sciences. The Biomaterials field has noticed a revolutionary growth since the application of old medical devices used in the late 1940s and early 1050s.1 This field progressed with the industrial revolution, increasing population, advances in medical health, luxurious life standards, and previously untreatable medical conditions that caused dire health crises to humanity. Right after World War II, the scientists started working on the biomaterials by dint off. Biomedicals experienced a revolutionary generation with an average gap of 10-20 years approximately. The first-generation biomaterials era is supposed to be between the 1950s–1960s. These materials were mainly used for industrial purposes rather than being specifically used for medical purposes. They were merely the conjugation of physical properties particular to use in the clinical field and also because they were bioinert, that is why they thought to be biocompatible.2 The extensively used silicone rubbers and elastomeric polymers were prototypical. Pyrolytic carbon was synthesized in the early 1960s as a material used for fuel-related components like fuel particles. But today, it is widely used to coat the mechanical heart valves, they are considered to be the earliest biomaterials whose properties and composition were analyzed thoroughly by using the principles of engineering.3 The second-generation biomaterials are evolved from previous biomaterials that were designed to show a therapeutic effect after being implanted in human tissues. In the 1980s these biomaterials were extensively used in dental, orthopedic, ocular surgeries. In the controlled localized drugs release applications like Norplant hormone-loaded contraceptive formulations, and in other devices like HeartMate, a device that is used to assist left ventricle in patients who have congestive heart failure. This aforementioned device is internally composed of Polyurethane, a material that controls a thrombotic pathology to reduce the risk of de-adhering fractions of blood clots into the bloodstream of patients. Drug-eluting endovascular stents is another exemplary precedent of the second-generation biomaterials used in medical devices that helps in controlling the restenosis following balloon angioplasty.4,5 The third and the most revolutionary generation of biomaterials elicits the novel art of science and technology, that are bestowed with the goal of regeneration of functional human tissues. Throughout the medical history of humans, medical scientists, physicians were unable to restore and regenerate the infected tissues and organs of humans. The role of the physician was very palliative – relieving symptoms without curing. The boom in regenerative medicine and tissue engineering broke all previous stereotypes by replacing the infected tissues and organs with implants. As we can see now these both medical domains are widely being used in therapeutics. The term tissue engineering is a broad concept that inter-relates the biomedical, engineering, medical sciences principles simultaneously.6 The advances in hip joint prosthesis are another precedent of the third generation of biomaterials, they are fabricated from a plethora of materials like titanium, composites, ceramics, Ultrahigh molecular weight polyethylene, and special high strength alloys. The contemporary Intraocular lenses which are made from a biopolymer named Polymethyl methacrylate have also played a tremendous role in treating and correcting vision problems, Per-Ingvar Branemark revolutionized the dental implantology by introducing the development of roots from titanium, an applaudable use of Polyethylene terephthalate and Polytetrafluoroethylene in dialysis machine also helped medical practitioners in treating kidneys diseases, the suturing techniques uses biomaterials mainly Polyglactin, Polypropylene, Polydioxanone, etc. also helping the surgeons in vascular and skin grafting of patients and the list does not end here. Almost everything that we use in our daily life is the contemporary blessings of biomaterials.7 Biomaterials, Prosthesis, generations of biomaterials, polymers Medicine R Sana Saeed verfasserin aut In Journal of Rawalpindi Medical College Rawalpindi Medical University, 2020 25(2021), 3 (DE-627)1735713449 16833570 nnns volume:25 year:2021 number:3 https://doi.org/10.37939/jrmc.v25i3.1649 kostenfrei https://doaj.org/article/448224d893cd44debea327a89767f3ba kostenfrei https://www.journalrmc.com/index.php/JRMC/article/view/1649 kostenfrei https://doaj.org/toc/1683-3562 Journal toc kostenfrei https://doaj.org/toc/1683-3570 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 25 2021 3
spelling	10.37939/jrmc.v25i3.1649 doi (DE-627)DOAJ046142215 (DE-599)DOAJ448224d893cd44debea327a89767f3ba DE-627 ger DE-627 rakwb eng Taimoor Hassan verfasserin aut A Revolution of Biomaterials in Medical Sciences 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Biomaterial science discusses diagnostics and therapeutics; it encloses the basic sciences (Chemistry, Physics, Biology, and Mathematics), medical sciences, and engineering sciences. The Biomaterials field has noticed a revolutionary growth since the application of old medical devices used in the late 1940s and early 1050s.1 This field progressed with the industrial revolution, increasing population, advances in medical health, luxurious life standards, and previously untreatable medical conditions that caused dire health crises to humanity. Right after World War II, the scientists started working on the biomaterials by dint off. Biomedicals experienced a revolutionary generation with an average gap of 10-20 years approximately. The first-generation biomaterials era is supposed to be between the 1950s–1960s. These materials were mainly used for industrial purposes rather than being specifically used for medical purposes. They were merely the conjugation of physical properties particular to use in the clinical field and also because they were bioinert, that is why they thought to be biocompatible.2 The extensively used silicone rubbers and elastomeric polymers were prototypical. Pyrolytic carbon was synthesized in the early 1960s as a material used for fuel-related components like fuel particles. But today, it is widely used to coat the mechanical heart valves, they are considered to be the earliest biomaterials whose properties and composition were analyzed thoroughly by using the principles of engineering.3 The second-generation biomaterials are evolved from previous biomaterials that were designed to show a therapeutic effect after being implanted in human tissues. In the 1980s these biomaterials were extensively used in dental, orthopedic, ocular surgeries. In the controlled localized drugs release applications like Norplant hormone-loaded contraceptive formulations, and in other devices like HeartMate, a device that is used to assist left ventricle in patients who have congestive heart failure. This aforementioned device is internally composed of Polyurethane, a material that controls a thrombotic pathology to reduce the risk of de-adhering fractions of blood clots into the bloodstream of patients. Drug-eluting endovascular stents is another exemplary precedent of the second-generation biomaterials used in medical devices that helps in controlling the restenosis following balloon angioplasty.4,5 The third and the most revolutionary generation of biomaterials elicits the novel art of science and technology, that are bestowed with the goal of regeneration of functional human tissues. Throughout the medical history of humans, medical scientists, physicians were unable to restore and regenerate the infected tissues and organs of humans. The role of the physician was very palliative – relieving symptoms without curing. The boom in regenerative medicine and tissue engineering broke all previous stereotypes by replacing the infected tissues and organs with implants. As we can see now these both medical domains are widely being used in therapeutics. The term tissue engineering is a broad concept that inter-relates the biomedical, engineering, medical sciences principles simultaneously.6 The advances in hip joint prosthesis are another precedent of the third generation of biomaterials, they are fabricated from a plethora of materials like titanium, composites, ceramics, Ultrahigh molecular weight polyethylene, and special high strength alloys. The contemporary Intraocular lenses which are made from a biopolymer named Polymethyl methacrylate have also played a tremendous role in treating and correcting vision problems, Per-Ingvar Branemark revolutionized the dental implantology by introducing the development of roots from titanium, an applaudable use of Polyethylene terephthalate and Polytetrafluoroethylene in dialysis machine also helped medical practitioners in treating kidneys diseases, the suturing techniques uses biomaterials mainly Polyglactin, Polypropylene, Polydioxanone, etc. also helping the surgeons in vascular and skin grafting of patients and the list does not end here. Almost everything that we use in our daily life is the contemporary blessings of biomaterials.7 Biomaterials, Prosthesis, generations of biomaterials, polymers Medicine R Sana Saeed verfasserin aut In Journal of Rawalpindi Medical College Rawalpindi Medical University, 2020 25(2021), 3 (DE-627)1735713449 16833570 nnns volume:25 year:2021 number:3 https://doi.org/10.37939/jrmc.v25i3.1649 kostenfrei https://doaj.org/article/448224d893cd44debea327a89767f3ba kostenfrei https://www.journalrmc.com/index.php/JRMC/article/view/1649 kostenfrei https://doaj.org/toc/1683-3562 Journal toc kostenfrei https://doaj.org/toc/1683-3570 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 25 2021 3
allfields_unstemmed	10.37939/jrmc.v25i3.1649 doi (DE-627)DOAJ046142215 (DE-599)DOAJ448224d893cd44debea327a89767f3ba DE-627 ger DE-627 rakwb eng Taimoor Hassan verfasserin aut A Revolution of Biomaterials in Medical Sciences 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Biomaterial science discusses diagnostics and therapeutics; it encloses the basic sciences (Chemistry, Physics, Biology, and Mathematics), medical sciences, and engineering sciences. The Biomaterials field has noticed a revolutionary growth since the application of old medical devices used in the late 1940s and early 1050s.1 This field progressed with the industrial revolution, increasing population, advances in medical health, luxurious life standards, and previously untreatable medical conditions that caused dire health crises to humanity. Right after World War II, the scientists started working on the biomaterials by dint off. Biomedicals experienced a revolutionary generation with an average gap of 10-20 years approximately. The first-generation biomaterials era is supposed to be between the 1950s–1960s. These materials were mainly used for industrial purposes rather than being specifically used for medical purposes. They were merely the conjugation of physical properties particular to use in the clinical field and also because they were bioinert, that is why they thought to be biocompatible.2 The extensively used silicone rubbers and elastomeric polymers were prototypical. Pyrolytic carbon was synthesized in the early 1960s as a material used for fuel-related components like fuel particles. But today, it is widely used to coat the mechanical heart valves, they are considered to be the earliest biomaterials whose properties and composition were analyzed thoroughly by using the principles of engineering.3 The second-generation biomaterials are evolved from previous biomaterials that were designed to show a therapeutic effect after being implanted in human tissues. In the 1980s these biomaterials were extensively used in dental, orthopedic, ocular surgeries. In the controlled localized drugs release applications like Norplant hormone-loaded contraceptive formulations, and in other devices like HeartMate, a device that is used to assist left ventricle in patients who have congestive heart failure. This aforementioned device is internally composed of Polyurethane, a material that controls a thrombotic pathology to reduce the risk of de-adhering fractions of blood clots into the bloodstream of patients. Drug-eluting endovascular stents is another exemplary precedent of the second-generation biomaterials used in medical devices that helps in controlling the restenosis following balloon angioplasty.4,5 The third and the most revolutionary generation of biomaterials elicits the novel art of science and technology, that are bestowed with the goal of regeneration of functional human tissues. Throughout the medical history of humans, medical scientists, physicians were unable to restore and regenerate the infected tissues and organs of humans. The role of the physician was very palliative – relieving symptoms without curing. The boom in regenerative medicine and tissue engineering broke all previous stereotypes by replacing the infected tissues and organs with implants. As we can see now these both medical domains are widely being used in therapeutics. The term tissue engineering is a broad concept that inter-relates the biomedical, engineering, medical sciences principles simultaneously.6 The advances in hip joint prosthesis are another precedent of the third generation of biomaterials, they are fabricated from a plethora of materials like titanium, composites, ceramics, Ultrahigh molecular weight polyethylene, and special high strength alloys. The contemporary Intraocular lenses which are made from a biopolymer named Polymethyl methacrylate have also played a tremendous role in treating and correcting vision problems, Per-Ingvar Branemark revolutionized the dental implantology by introducing the development of roots from titanium, an applaudable use of Polyethylene terephthalate and Polytetrafluoroethylene in dialysis machine also helped medical practitioners in treating kidneys diseases, the suturing techniques uses biomaterials mainly Polyglactin, Polypropylene, Polydioxanone, etc. also helping the surgeons in vascular and skin grafting of patients and the list does not end here. Almost everything that we use in our daily life is the contemporary blessings of biomaterials.7 Biomaterials, Prosthesis, generations of biomaterials, polymers Medicine R Sana Saeed verfasserin aut In Journal of Rawalpindi Medical College Rawalpindi Medical University, 2020 25(2021), 3 (DE-627)1735713449 16833570 nnns volume:25 year:2021 number:3 https://doi.org/10.37939/jrmc.v25i3.1649 kostenfrei https://doaj.org/article/448224d893cd44debea327a89767f3ba kostenfrei https://www.journalrmc.com/index.php/JRMC/article/view/1649 kostenfrei https://doaj.org/toc/1683-3562 Journal toc kostenfrei https://doaj.org/toc/1683-3570 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 25 2021 3
allfieldsGer	10.37939/jrmc.v25i3.1649 doi (DE-627)DOAJ046142215 (DE-599)DOAJ448224d893cd44debea327a89767f3ba DE-627 ger DE-627 rakwb eng Taimoor Hassan verfasserin aut A Revolution of Biomaterials in Medical Sciences 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Biomaterial science discusses diagnostics and therapeutics; it encloses the basic sciences (Chemistry, Physics, Biology, and Mathematics), medical sciences, and engineering sciences. The Biomaterials field has noticed a revolutionary growth since the application of old medical devices used in the late 1940s and early 1050s.1 This field progressed with the industrial revolution, increasing population, advances in medical health, luxurious life standards, and previously untreatable medical conditions that caused dire health crises to humanity. Right after World War II, the scientists started working on the biomaterials by dint off. Biomedicals experienced a revolutionary generation with an average gap of 10-20 years approximately. The first-generation biomaterials era is supposed to be between the 1950s–1960s. These materials were mainly used for industrial purposes rather than being specifically used for medical purposes. They were merely the conjugation of physical properties particular to use in the clinical field and also because they were bioinert, that is why they thought to be biocompatible.2 The extensively used silicone rubbers and elastomeric polymers were prototypical. Pyrolytic carbon was synthesized in the early 1960s as a material used for fuel-related components like fuel particles. But today, it is widely used to coat the mechanical heart valves, they are considered to be the earliest biomaterials whose properties and composition were analyzed thoroughly by using the principles of engineering.3 The second-generation biomaterials are evolved from previous biomaterials that were designed to show a therapeutic effect after being implanted in human tissues. In the 1980s these biomaterials were extensively used in dental, orthopedic, ocular surgeries. In the controlled localized drugs release applications like Norplant hormone-loaded contraceptive formulations, and in other devices like HeartMate, a device that is used to assist left ventricle in patients who have congestive heart failure. This aforementioned device is internally composed of Polyurethane, a material that controls a thrombotic pathology to reduce the risk of de-adhering fractions of blood clots into the bloodstream of patients. Drug-eluting endovascular stents is another exemplary precedent of the second-generation biomaterials used in medical devices that helps in controlling the restenosis following balloon angioplasty.4,5 The third and the most revolutionary generation of biomaterials elicits the novel art of science and technology, that are bestowed with the goal of regeneration of functional human tissues. Throughout the medical history of humans, medical scientists, physicians were unable to restore and regenerate the infected tissues and organs of humans. The role of the physician was very palliative – relieving symptoms without curing. The boom in regenerative medicine and tissue engineering broke all previous stereotypes by replacing the infected tissues and organs with implants. As we can see now these both medical domains are widely being used in therapeutics. The term tissue engineering is a broad concept that inter-relates the biomedical, engineering, medical sciences principles simultaneously.6 The advances in hip joint prosthesis are another precedent of the third generation of biomaterials, they are fabricated from a plethora of materials like titanium, composites, ceramics, Ultrahigh molecular weight polyethylene, and special high strength alloys. The contemporary Intraocular lenses which are made from a biopolymer named Polymethyl methacrylate have also played a tremendous role in treating and correcting vision problems, Per-Ingvar Branemark revolutionized the dental implantology by introducing the development of roots from titanium, an applaudable use of Polyethylene terephthalate and Polytetrafluoroethylene in dialysis machine also helped medical practitioners in treating kidneys diseases, the suturing techniques uses biomaterials mainly Polyglactin, Polypropylene, Polydioxanone, etc. also helping the surgeons in vascular and skin grafting of patients and the list does not end here. Almost everything that we use in our daily life is the contemporary blessings of biomaterials.7 Biomaterials, Prosthesis, generations of biomaterials, polymers Medicine R Sana Saeed verfasserin aut In Journal of Rawalpindi Medical College Rawalpindi Medical University, 2020 25(2021), 3 (DE-627)1735713449 16833570 nnns volume:25 year:2021 number:3 https://doi.org/10.37939/jrmc.v25i3.1649 kostenfrei https://doaj.org/article/448224d893cd44debea327a89767f3ba kostenfrei https://www.journalrmc.com/index.php/JRMC/article/view/1649 kostenfrei https://doaj.org/toc/1683-3562 Journal toc kostenfrei https://doaj.org/toc/1683-3570 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 25 2021 3
allfieldsSound	10.37939/jrmc.v25i3.1649 doi (DE-627)DOAJ046142215 (DE-599)DOAJ448224d893cd44debea327a89767f3ba DE-627 ger DE-627 rakwb eng Taimoor Hassan verfasserin aut A Revolution of Biomaterials in Medical Sciences 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Biomaterial science discusses diagnostics and therapeutics; it encloses the basic sciences (Chemistry, Physics, Biology, and Mathematics), medical sciences, and engineering sciences. The Biomaterials field has noticed a revolutionary growth since the application of old medical devices used in the late 1940s and early 1050s.1 This field progressed with the industrial revolution, increasing population, advances in medical health, luxurious life standards, and previously untreatable medical conditions that caused dire health crises to humanity. Right after World War II, the scientists started working on the biomaterials by dint off. Biomedicals experienced a revolutionary generation with an average gap of 10-20 years approximately. The first-generation biomaterials era is supposed to be between the 1950s–1960s. These materials were mainly used for industrial purposes rather than being specifically used for medical purposes. They were merely the conjugation of physical properties particular to use in the clinical field and also because they were bioinert, that is why they thought to be biocompatible.2 The extensively used silicone rubbers and elastomeric polymers were prototypical. Pyrolytic carbon was synthesized in the early 1960s as a material used for fuel-related components like fuel particles. But today, it is widely used to coat the mechanical heart valves, they are considered to be the earliest biomaterials whose properties and composition were analyzed thoroughly by using the principles of engineering.3 The second-generation biomaterials are evolved from previous biomaterials that were designed to show a therapeutic effect after being implanted in human tissues. In the 1980s these biomaterials were extensively used in dental, orthopedic, ocular surgeries. In the controlled localized drugs release applications like Norplant hormone-loaded contraceptive formulations, and in other devices like HeartMate, a device that is used to assist left ventricle in patients who have congestive heart failure. This aforementioned device is internally composed of Polyurethane, a material that controls a thrombotic pathology to reduce the risk of de-adhering fractions of blood clots into the bloodstream of patients. Drug-eluting endovascular stents is another exemplary precedent of the second-generation biomaterials used in medical devices that helps in controlling the restenosis following balloon angioplasty.4,5 The third and the most revolutionary generation of biomaterials elicits the novel art of science and technology, that are bestowed with the goal of regeneration of functional human tissues. Throughout the medical history of humans, medical scientists, physicians were unable to restore and regenerate the infected tissues and organs of humans. The role of the physician was very palliative – relieving symptoms without curing. The boom in regenerative medicine and tissue engineering broke all previous stereotypes by replacing the infected tissues and organs with implants. As we can see now these both medical domains are widely being used in therapeutics. The term tissue engineering is a broad concept that inter-relates the biomedical, engineering, medical sciences principles simultaneously.6 The advances in hip joint prosthesis are another precedent of the third generation of biomaterials, they are fabricated from a plethora of materials like titanium, composites, ceramics, Ultrahigh molecular weight polyethylene, and special high strength alloys. The contemporary Intraocular lenses which are made from a biopolymer named Polymethyl methacrylate have also played a tremendous role in treating and correcting vision problems, Per-Ingvar Branemark revolutionized the dental implantology by introducing the development of roots from titanium, an applaudable use of Polyethylene terephthalate and Polytetrafluoroethylene in dialysis machine also helped medical practitioners in treating kidneys diseases, the suturing techniques uses biomaterials mainly Polyglactin, Polypropylene, Polydioxanone, etc. also helping the surgeons in vascular and skin grafting of patients and the list does not end here. Almost everything that we use in our daily life is the contemporary blessings of biomaterials.7 Biomaterials, Prosthesis, generations of biomaterials, polymers Medicine R Sana Saeed verfasserin aut In Journal of Rawalpindi Medical College Rawalpindi Medical University, 2020 25(2021), 3 (DE-627)1735713449 16833570 nnns volume:25 year:2021 number:3 https://doi.org/10.37939/jrmc.v25i3.1649 kostenfrei https://doaj.org/article/448224d893cd44debea327a89767f3ba kostenfrei https://www.journalrmc.com/index.php/JRMC/article/view/1649 kostenfrei https://doaj.org/toc/1683-3562 Journal toc kostenfrei https://doaj.org/toc/1683-3570 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 25 2021 3
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In the controlled localized drugs release applications like Norplant hormone-loaded contraceptive formulations, and in other devices like HeartMate, a device that is used to assist left ventricle in patients who have congestive heart failure. This aforementioned device is internally composed of Polyurethane, a material that controls a thrombotic pathology to reduce the risk of de-adhering fractions of blood clots into the bloodstream of patients. Drug-eluting endovascular stents is another exemplary precedent of the second-generation biomaterials used in medical devices that helps in controlling the restenosis following balloon angioplasty.4,5 The third and the most revolutionary generation of biomaterials elicits the novel art of science and technology, that are bestowed with the goal of regeneration of functional human tissues. Throughout the medical history of humans, medical scientists, physicians were unable to restore and regenerate the infected tissues and organs of humans. 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title_sort	revolution of biomaterials in medical sciences
title_auth	A Revolution of Biomaterials in Medical Sciences
abstract	Biomaterial science discusses diagnostics and therapeutics; it encloses the basic sciences (Chemistry, Physics, Biology, and Mathematics), medical sciences, and engineering sciences. The Biomaterials field has noticed a revolutionary growth since the application of old medical devices used in the late 1940s and early 1050s.1 This field progressed with the industrial revolution, increasing population, advances in medical health, luxurious life standards, and previously untreatable medical conditions that caused dire health crises to humanity. Right after World War II, the scientists started working on the biomaterials by dint off. Biomedicals experienced a revolutionary generation with an average gap of 10-20 years approximately. The first-generation biomaterials era is supposed to be between the 1950s–1960s. These materials were mainly used for industrial purposes rather than being specifically used for medical purposes. They were merely the conjugation of physical properties particular to use in the clinical field and also because they were bioinert, that is why they thought to be biocompatible.2 The extensively used silicone rubbers and elastomeric polymers were prototypical. Pyrolytic carbon was synthesized in the early 1960s as a material used for fuel-related components like fuel particles. But today, it is widely used to coat the mechanical heart valves, they are considered to be the earliest biomaterials whose properties and composition were analyzed thoroughly by using the principles of engineering.3 The second-generation biomaterials are evolved from previous biomaterials that were designed to show a therapeutic effect after being implanted in human tissues. In the 1980s these biomaterials were extensively used in dental, orthopedic, ocular surgeries. In the controlled localized drugs release applications like Norplant hormone-loaded contraceptive formulations, and in other devices like HeartMate, a device that is used to assist left ventricle in patients who have congestive heart failure. This aforementioned device is internally composed of Polyurethane, a material that controls a thrombotic pathology to reduce the risk of de-adhering fractions of blood clots into the bloodstream of patients. Drug-eluting endovascular stents is another exemplary precedent of the second-generation biomaterials used in medical devices that helps in controlling the restenosis following balloon angioplasty.4,5 The third and the most revolutionary generation of biomaterials elicits the novel art of science and technology, that are bestowed with the goal of regeneration of functional human tissues. Throughout the medical history of humans, medical scientists, physicians were unable to restore and regenerate the infected tissues and organs of humans. The role of the physician was very palliative – relieving symptoms without curing. The boom in regenerative medicine and tissue engineering broke all previous stereotypes by replacing the infected tissues and organs with implants. As we can see now these both medical domains are widely being used in therapeutics. The term tissue engineering is a broad concept that inter-relates the biomedical, engineering, medical sciences principles simultaneously.6 The advances in hip joint prosthesis are another precedent of the third generation of biomaterials, they are fabricated from a plethora of materials like titanium, composites, ceramics, Ultrahigh molecular weight polyethylene, and special high strength alloys. The contemporary Intraocular lenses which are made from a biopolymer named Polymethyl methacrylate have also played a tremendous role in treating and correcting vision problems, Per-Ingvar Branemark revolutionized the dental implantology by introducing the development of roots from titanium, an applaudable use of Polyethylene terephthalate and Polytetrafluoroethylene in dialysis machine also helped medical practitioners in treating kidneys diseases, the suturing techniques uses biomaterials mainly Polyglactin, Polypropylene, Polydioxanone, etc. also helping the surgeons in vascular and skin grafting of patients and the list does not end here. Almost everything that we use in our daily life is the contemporary blessings of biomaterials.7
abstractGer	Biomaterial science discusses diagnostics and therapeutics; it encloses the basic sciences (Chemistry, Physics, Biology, and Mathematics), medical sciences, and engineering sciences. The Biomaterials field has noticed a revolutionary growth since the application of old medical devices used in the late 1940s and early 1050s.1 This field progressed with the industrial revolution, increasing population, advances in medical health, luxurious life standards, and previously untreatable medical conditions that caused dire health crises to humanity. Right after World War II, the scientists started working on the biomaterials by dint off. Biomedicals experienced a revolutionary generation with an average gap of 10-20 years approximately. The first-generation biomaterials era is supposed to be between the 1950s–1960s. These materials were mainly used for industrial purposes rather than being specifically used for medical purposes. They were merely the conjugation of physical properties particular to use in the clinical field and also because they were bioinert, that is why they thought to be biocompatible.2 The extensively used silicone rubbers and elastomeric polymers were prototypical. Pyrolytic carbon was synthesized in the early 1960s as a material used for fuel-related components like fuel particles. But today, it is widely used to coat the mechanical heart valves, they are considered to be the earliest biomaterials whose properties and composition were analyzed thoroughly by using the principles of engineering.3 The second-generation biomaterials are evolved from previous biomaterials that were designed to show a therapeutic effect after being implanted in human tissues. In the 1980s these biomaterials were extensively used in dental, orthopedic, ocular surgeries. In the controlled localized drugs release applications like Norplant hormone-loaded contraceptive formulations, and in other devices like HeartMate, a device that is used to assist left ventricle in patients who have congestive heart failure. This aforementioned device is internally composed of Polyurethane, a material that controls a thrombotic pathology to reduce the risk of de-adhering fractions of blood clots into the bloodstream of patients. Drug-eluting endovascular stents is another exemplary precedent of the second-generation biomaterials used in medical devices that helps in controlling the restenosis following balloon angioplasty.4,5 The third and the most revolutionary generation of biomaterials elicits the novel art of science and technology, that are bestowed with the goal of regeneration of functional human tissues. Throughout the medical history of humans, medical scientists, physicians were unable to restore and regenerate the infected tissues and organs of humans. The role of the physician was very palliative – relieving symptoms without curing. The boom in regenerative medicine and tissue engineering broke all previous stereotypes by replacing the infected tissues and organs with implants. As we can see now these both medical domains are widely being used in therapeutics. The term tissue engineering is a broad concept that inter-relates the biomedical, engineering, medical sciences principles simultaneously.6 The advances in hip joint prosthesis are another precedent of the third generation of biomaterials, they are fabricated from a plethora of materials like titanium, composites, ceramics, Ultrahigh molecular weight polyethylene, and special high strength alloys. The contemporary Intraocular lenses which are made from a biopolymer named Polymethyl methacrylate have also played a tremendous role in treating and correcting vision problems, Per-Ingvar Branemark revolutionized the dental implantology by introducing the development of roots from titanium, an applaudable use of Polyethylene terephthalate and Polytetrafluoroethylene in dialysis machine also helped medical practitioners in treating kidneys diseases, the suturing techniques uses biomaterials mainly Polyglactin, Polypropylene, Polydioxanone, etc. also helping the surgeons in vascular and skin grafting of patients and the list does not end here. Almost everything that we use in our daily life is the contemporary blessings of biomaterials.7
abstract_unstemmed	Biomaterial science discusses diagnostics and therapeutics; it encloses the basic sciences (Chemistry, Physics, Biology, and Mathematics), medical sciences, and engineering sciences. The Biomaterials field has noticed a revolutionary growth since the application of old medical devices used in the late 1940s and early 1050s.1 This field progressed with the industrial revolution, increasing population, advances in medical health, luxurious life standards, and previously untreatable medical conditions that caused dire health crises to humanity. Right after World War II, the scientists started working on the biomaterials by dint off. Biomedicals experienced a revolutionary generation with an average gap of 10-20 years approximately. The first-generation biomaterials era is supposed to be between the 1950s–1960s. These materials were mainly used for industrial purposes rather than being specifically used for medical purposes. They were merely the conjugation of physical properties particular to use in the clinical field and also because they were bioinert, that is why they thought to be biocompatible.2 The extensively used silicone rubbers and elastomeric polymers were prototypical. Pyrolytic carbon was synthesized in the early 1960s as a material used for fuel-related components like fuel particles. But today, it is widely used to coat the mechanical heart valves, they are considered to be the earliest biomaterials whose properties and composition were analyzed thoroughly by using the principles of engineering.3 The second-generation biomaterials are evolved from previous biomaterials that were designed to show a therapeutic effect after being implanted in human tissues. In the 1980s these biomaterials were extensively used in dental, orthopedic, ocular surgeries. In the controlled localized drugs release applications like Norplant hormone-loaded contraceptive formulations, and in other devices like HeartMate, a device that is used to assist left ventricle in patients who have congestive heart failure. This aforementioned device is internally composed of Polyurethane, a material that controls a thrombotic pathology to reduce the risk of de-adhering fractions of blood clots into the bloodstream of patients. Drug-eluting endovascular stents is another exemplary precedent of the second-generation biomaterials used in medical devices that helps in controlling the restenosis following balloon angioplasty.4,5 The third and the most revolutionary generation of biomaterials elicits the novel art of science and technology, that are bestowed with the goal of regeneration of functional human tissues. Throughout the medical history of humans, medical scientists, physicians were unable to restore and regenerate the infected tissues and organs of humans. The role of the physician was very palliative – relieving symptoms without curing. The boom in regenerative medicine and tissue engineering broke all previous stereotypes by replacing the infected tissues and organs with implants. As we can see now these both medical domains are widely being used in therapeutics. The term tissue engineering is a broad concept that inter-relates the biomedical, engineering, medical sciences principles simultaneously.6 The advances in hip joint prosthesis are another precedent of the third generation of biomaterials, they are fabricated from a plethora of materials like titanium, composites, ceramics, Ultrahigh molecular weight polyethylene, and special high strength alloys. The contemporary Intraocular lenses which are made from a biopolymer named Polymethyl methacrylate have also played a tremendous role in treating and correcting vision problems, Per-Ingvar Branemark revolutionized the dental implantology by introducing the development of roots from titanium, an applaudable use of Polyethylene terephthalate and Polytetrafluoroethylene in dialysis machine also helped medical practitioners in treating kidneys diseases, the suturing techniques uses biomaterials mainly Polyglactin, Polypropylene, Polydioxanone, etc. also helping the surgeons in vascular and skin grafting of patients and the list does not end here. Almost everything that we use in our daily life is the contemporary blessings of biomaterials.7
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title_short	A Revolution of Biomaterials in Medical Sciences
url	https://doi.org/10.37939/jrmc.v25i3.1649 https://doaj.org/article/448224d893cd44debea327a89767f3ba https://www.journalrmc.com/index.php/JRMC/article/view/1649 https://doaj.org/toc/1683-3562 https://doaj.org/toc/1683-3570
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doi_str	10.37939/jrmc.v25i3.1649
up_date	2024-07-03T19:00:45.002Z
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