The Effects of Patient Education on Psychological Status and Clinical Outcomes in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis

BackgroundRheumatoid arthritis (RA) is a common systemic inflammatory autoimmune disease. The disease has a serious impact on mental health and requires more effective non-pharmacological interventions.ObjectiveThis study aims to systematically evaluate the effectiveness of patient education on psychological status and clinical outcomes in rheumatoid arthritis.MethodsThis systematic review and meta-analysis was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PubMed, Cochrane Library, EMBASE database, and Web of Science database were screened for articles published until November 2, 2021. Randomized controlled trials (RCTs) of patient education for RA were included. Outcomes measures included pain, physical function, disease activity, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), anxiety, depression, Arthritis Self-Efficacy (pain, other symptoms, total), and General health. For each outcome, standardized mean differences or mean differences and 95% confidence intervals (CIs) were calculated.ResultsA total of 24 RCTs (n = 2,276) were included according to the inclusion and exclusion criteria. Meta-analysis revealed a statistically significant overall effect in favor of patient education for physical function [SMD = −0.52, 95% CI (−0.96, −0.08), I2 = 93%, P = 0.02], disease activity [SMD = −1.97, 95% CI (−3.24, −0.71), I2 = 97%, P = 0.002], ASE (pain) [SMD = −1.24, 95% CI (−2.05, −0.43), I2 = 95%, P = 0.003], ASE (other symptoms) [SMD = −0.25, 95% CI (−0.41, −0.09), I2 = 25%, P = 0.002], ASE (total) [SMD = −0.67, 95% CI (−1.30, −0.05), I2 = 90%, P = 0.03], and general health [SMD = −1.11, 95% CI (−1.36, −0.86), I2 = 96%, P < 0.00001]. No effects were found for anxiety [SMD = 0.17, 95% CI (−0.64, 0.98), I2 = 82%, P = 0.68], depression [SMD = −0.18, 95% CI (−0.52, 0.15), I2 = 52%, P = 0.28], pain [SMD = −0.37, 95% CI (−0.80, 0.05), I2 = 89%, P = 0.08], and CRP [SMD = −0.27, 95% CI (−0.57, 0.02), I2 = 0%, P = 0.07].ConclusionsPatient education may be effective in improving clinical outcomes and psychological status in patients with rheumatoid arthritis. Considering the methodological limitations of the included RCTs, more high-quality and large-sample RCTs are needed to confirm this conclusion in the future.Systematic Review Registrationhttp://www.crd.york.ac.uk/prospero, identifier: CRD42021250607. Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Zugui Wu [verfasserIn] Yue Zhu [verfasserIn] Yi Wang [verfasserIn] Rui Zhou [verfasserIn] Xiangling Ye [verfasserIn] Zehua Chen [verfasserIn] Congcong Li [verfasserIn] Junyi Li [verfasserIn] Zixuan Ye [verfasserIn] Zhenbang Wang [verfasserIn] Wengang Liu [verfasserIn] Xuemeng Xu [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022

Schlagwörter:	patient education psychotherapy rheumatoid arthritis meta-analysis systematic review

Übergeordnetes Werk:	In: Frontiers in Psychiatry - Frontiers Media S.A., 2010, 13(2022)
Übergeordnetes Werk:	volume:13 ; year:2022

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3389/fpsyt.2022.848427

Katalog-ID:	DOAJ04652097X

Internformat


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520			\|a BackgroundRheumatoid arthritis (RA) is a common systemic inflammatory autoimmune disease. The disease has a serious impact on mental health and requires more effective non-pharmacological interventions.ObjectiveThis study aims to systematically evaluate the effectiveness of patient education on psychological status and clinical outcomes in rheumatoid arthritis.MethodsThis systematic review and meta-analysis was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PubMed, Cochrane Library, EMBASE database, and Web of Science database were screened for articles published until November 2, 2021. Randomized controlled trials (RCTs) of patient education for RA were included. Outcomes measures included pain, physical function, disease activity, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), anxiety, depression, Arthritis Self-Efficacy (pain, other symptoms, total), and General health. For each outcome, standardized mean differences or mean differences and 95% confidence intervals (CIs) were calculated.ResultsA total of 24 RCTs (n = 2,276) were included according to the inclusion and exclusion criteria. Meta-analysis revealed a statistically significant overall effect in favor of patient education for physical function [SMD = −0.52, 95% CI (−0.96, −0.08), I2 = 93%, P = 0.02], disease activity [SMD = −1.97, 95% CI (−3.24, −0.71), I2 = 97%, P = 0.002], ASE (pain) [SMD = −1.24, 95% CI (−2.05, −0.43), I2 = 95%, P = 0.003], ASE (other symptoms) [SMD = −0.25, 95% CI (−0.41, −0.09), I2 = 25%, P = 0.002], ASE (total) [SMD = −0.67, 95% CI (−1.30, −0.05), I2 = 90%, P = 0.03], and general health [SMD = −1.11, 95% CI (−1.36, −0.86), I2 = 96%, P < 0.00001]. No effects were found for anxiety [SMD = 0.17, 95% CI (−0.64, 0.98), I2 = 82%, P = 0.68], depression [SMD = −0.18, 95% CI (−0.52, 0.15), I2 = 52%, P = 0.28], pain [SMD = −0.37, 95% CI (−0.80, 0.05), I2 = 89%, P = 0.08], and CRP [SMD = −0.27, 95% CI (−0.57, 0.02), I2 = 0%, P = 0.07].ConclusionsPatient education may be effective in improving clinical outcomes and psychological status in patients with rheumatoid arthritis. Considering the methodological limitations of the included RCTs, more high-quality and large-sample RCTs are needed to confirm this conclusion in the future.Systematic Review Registrationhttp://www.crd.york.ac.uk/prospero, identifier: CRD42021250607.
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allfields	10.3389/fpsyt.2022.848427 doi (DE-627)DOAJ04652097X (DE-599)DOAJfda0ee3d5a4d449aa593d3a2e1fdb259 DE-627 ger DE-627 rakwb eng RC435-571 Zugui Wu verfasserin aut The Effects of Patient Education on Psychological Status and Clinical Outcomes in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier BackgroundRheumatoid arthritis (RA) is a common systemic inflammatory autoimmune disease. The disease has a serious impact on mental health and requires more effective non-pharmacological interventions.ObjectiveThis study aims to systematically evaluate the effectiveness of patient education on psychological status and clinical outcomes in rheumatoid arthritis.MethodsThis systematic review and meta-analysis was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PubMed, Cochrane Library, EMBASE database, and Web of Science database were screened for articles published until November 2, 2021. Randomized controlled trials (RCTs) of patient education for RA were included. Outcomes measures included pain, physical function, disease activity, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), anxiety, depression, Arthritis Self-Efficacy (pain, other symptoms, total), and General health. For each outcome, standardized mean differences or mean differences and 95% confidence intervals (CIs) were calculated.ResultsA total of 24 RCTs (n = 2,276) were included according to the inclusion and exclusion criteria. Meta-analysis revealed a statistically significant overall effect in favor of patient education for physical function [SMD = −0.52, 95% CI (−0.96, −0.08), I2 = 93%, P = 0.02], disease activity [SMD = −1.97, 95% CI (−3.24, −0.71), I2 = 97%, P = 0.002], ASE (pain) [SMD = −1.24, 95% CI (−2.05, −0.43), I2 = 95%, P = 0.003], ASE (other symptoms) [SMD = −0.25, 95% CI (−0.41, −0.09), I2 = 25%, P = 0.002], ASE (total) [SMD = −0.67, 95% CI (−1.30, −0.05), I2 = 90%, P = 0.03], and general health [SMD = −1.11, 95% CI (−1.36, −0.86), I2 = 96%, P < 0.00001]. No effects were found for anxiety [SMD = 0.17, 95% CI (−0.64, 0.98), I2 = 82%, P = 0.68], depression [SMD = −0.18, 95% CI (−0.52, 0.15), I2 = 52%, P = 0.28], pain [SMD = −0.37, 95% CI (−0.80, 0.05), I2 = 89%, P = 0.08], and CRP [SMD = −0.27, 95% CI (−0.57, 0.02), I2 = 0%, P = 0.07].ConclusionsPatient education may be effective in improving clinical outcomes and psychological status in patients with rheumatoid arthritis. Considering the methodological limitations of the included RCTs, more high-quality and large-sample RCTs are needed to confirm this conclusion in the future.Systematic Review Registrationhttp://www.crd.york.ac.uk/prospero, identifier: CRD42021250607. patient education psychotherapy rheumatoid arthritis meta-analysis systematic review Psychiatry Yue Zhu verfasserin aut Yi Wang verfasserin aut Rui Zhou verfasserin aut Xiangling Ye verfasserin aut Zehua Chen verfasserin aut Congcong Li verfasserin aut Junyi Li verfasserin aut Zixuan Ye verfasserin aut Zhenbang Wang verfasserin aut Wengang Liu verfasserin aut Wengang Liu verfasserin aut Xuemeng Xu verfasserin aut Xuemeng Xu verfasserin aut In Frontiers in Psychiatry Frontiers Media S.A., 2010 13(2022) (DE-627)631498796 (DE-600)2564218-2 16640640 nnns volume:13 year:2022 https://doi.org/10.3389/fpsyt.2022.848427 kostenfrei https://doaj.org/article/fda0ee3d5a4d449aa593d3a2e1fdb259 kostenfrei https://www.frontiersin.org/articles/10.3389/fpsyt.2022.848427/full kostenfrei https://doaj.org/toc/1664-0640 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2022
spelling	10.3389/fpsyt.2022.848427 doi (DE-627)DOAJ04652097X (DE-599)DOAJfda0ee3d5a4d449aa593d3a2e1fdb259 DE-627 ger DE-627 rakwb eng RC435-571 Zugui Wu verfasserin aut The Effects of Patient Education on Psychological Status and Clinical Outcomes in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier BackgroundRheumatoid arthritis (RA) is a common systemic inflammatory autoimmune disease. The disease has a serious impact on mental health and requires more effective non-pharmacological interventions.ObjectiveThis study aims to systematically evaluate the effectiveness of patient education on psychological status and clinical outcomes in rheumatoid arthritis.MethodsThis systematic review and meta-analysis was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PubMed, Cochrane Library, EMBASE database, and Web of Science database were screened for articles published until November 2, 2021. Randomized controlled trials (RCTs) of patient education for RA were included. Outcomes measures included pain, physical function, disease activity, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), anxiety, depression, Arthritis Self-Efficacy (pain, other symptoms, total), and General health. For each outcome, standardized mean differences or mean differences and 95% confidence intervals (CIs) were calculated.ResultsA total of 24 RCTs (n = 2,276) were included according to the inclusion and exclusion criteria. Meta-analysis revealed a statistically significant overall effect in favor of patient education for physical function [SMD = −0.52, 95% CI (−0.96, −0.08), I2 = 93%, P = 0.02], disease activity [SMD = −1.97, 95% CI (−3.24, −0.71), I2 = 97%, P = 0.002], ASE (pain) [SMD = −1.24, 95% CI (−2.05, −0.43), I2 = 95%, P = 0.003], ASE (other symptoms) [SMD = −0.25, 95% CI (−0.41, −0.09), I2 = 25%, P = 0.002], ASE (total) [SMD = −0.67, 95% CI (−1.30, −0.05), I2 = 90%, P = 0.03], and general health [SMD = −1.11, 95% CI (−1.36, −0.86), I2 = 96%, P < 0.00001]. No effects were found for anxiety [SMD = 0.17, 95% CI (−0.64, 0.98), I2 = 82%, P = 0.68], depression [SMD = −0.18, 95% CI (−0.52, 0.15), I2 = 52%, P = 0.28], pain [SMD = −0.37, 95% CI (−0.80, 0.05), I2 = 89%, P = 0.08], and CRP [SMD = −0.27, 95% CI (−0.57, 0.02), I2 = 0%, P = 0.07].ConclusionsPatient education may be effective in improving clinical outcomes and psychological status in patients with rheumatoid arthritis. Considering the methodological limitations of the included RCTs, more high-quality and large-sample RCTs are needed to confirm this conclusion in the future.Systematic Review Registrationhttp://www.crd.york.ac.uk/prospero, identifier: CRD42021250607. patient education psychotherapy rheumatoid arthritis meta-analysis systematic review Psychiatry Yue Zhu verfasserin aut Yi Wang verfasserin aut Rui Zhou verfasserin aut Xiangling Ye verfasserin aut Zehua Chen verfasserin aut Congcong Li verfasserin aut Junyi Li verfasserin aut Zixuan Ye verfasserin aut Zhenbang Wang verfasserin aut Wengang Liu verfasserin aut Wengang Liu verfasserin aut Xuemeng Xu verfasserin aut Xuemeng Xu verfasserin aut In Frontiers in Psychiatry Frontiers Media S.A., 2010 13(2022) (DE-627)631498796 (DE-600)2564218-2 16640640 nnns volume:13 year:2022 https://doi.org/10.3389/fpsyt.2022.848427 kostenfrei https://doaj.org/article/fda0ee3d5a4d449aa593d3a2e1fdb259 kostenfrei https://www.frontiersin.org/articles/10.3389/fpsyt.2022.848427/full kostenfrei https://doaj.org/toc/1664-0640 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2022
allfields_unstemmed	10.3389/fpsyt.2022.848427 doi (DE-627)DOAJ04652097X (DE-599)DOAJfda0ee3d5a4d449aa593d3a2e1fdb259 DE-627 ger DE-627 rakwb eng RC435-571 Zugui Wu verfasserin aut The Effects of Patient Education on Psychological Status and Clinical Outcomes in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier BackgroundRheumatoid arthritis (RA) is a common systemic inflammatory autoimmune disease. The disease has a serious impact on mental health and requires more effective non-pharmacological interventions.ObjectiveThis study aims to systematically evaluate the effectiveness of patient education on psychological status and clinical outcomes in rheumatoid arthritis.MethodsThis systematic review and meta-analysis was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PubMed, Cochrane Library, EMBASE database, and Web of Science database were screened for articles published until November 2, 2021. Randomized controlled trials (RCTs) of patient education for RA were included. Outcomes measures included pain, physical function, disease activity, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), anxiety, depression, Arthritis Self-Efficacy (pain, other symptoms, total), and General health. For each outcome, standardized mean differences or mean differences and 95% confidence intervals (CIs) were calculated.ResultsA total of 24 RCTs (n = 2,276) were included according to the inclusion and exclusion criteria. Meta-analysis revealed a statistically significant overall effect in favor of patient education for physical function [SMD = −0.52, 95% CI (−0.96, −0.08), I2 = 93%, P = 0.02], disease activity [SMD = −1.97, 95% CI (−3.24, −0.71), I2 = 97%, P = 0.002], ASE (pain) [SMD = −1.24, 95% CI (−2.05, −0.43), I2 = 95%, P = 0.003], ASE (other symptoms) [SMD = −0.25, 95% CI (−0.41, −0.09), I2 = 25%, P = 0.002], ASE (total) [SMD = −0.67, 95% CI (−1.30, −0.05), I2 = 90%, P = 0.03], and general health [SMD = −1.11, 95% CI (−1.36, −0.86), I2 = 96%, P < 0.00001]. No effects were found for anxiety [SMD = 0.17, 95% CI (−0.64, 0.98), I2 = 82%, P = 0.68], depression [SMD = −0.18, 95% CI (−0.52, 0.15), I2 = 52%, P = 0.28], pain [SMD = −0.37, 95% CI (−0.80, 0.05), I2 = 89%, P = 0.08], and CRP [SMD = −0.27, 95% CI (−0.57, 0.02), I2 = 0%, P = 0.07].ConclusionsPatient education may be effective in improving clinical outcomes and psychological status in patients with rheumatoid arthritis. Considering the methodological limitations of the included RCTs, more high-quality and large-sample RCTs are needed to confirm this conclusion in the future.Systematic Review Registrationhttp://www.crd.york.ac.uk/prospero, identifier: CRD42021250607. patient education psychotherapy rheumatoid arthritis meta-analysis systematic review Psychiatry Yue Zhu verfasserin aut Yi Wang verfasserin aut Rui Zhou verfasserin aut Xiangling Ye verfasserin aut Zehua Chen verfasserin aut Congcong Li verfasserin aut Junyi Li verfasserin aut Zixuan Ye verfasserin aut Zhenbang Wang verfasserin aut Wengang Liu verfasserin aut Wengang Liu verfasserin aut Xuemeng Xu verfasserin aut Xuemeng Xu verfasserin aut In Frontiers in Psychiatry Frontiers Media S.A., 2010 13(2022) (DE-627)631498796 (DE-600)2564218-2 16640640 nnns volume:13 year:2022 https://doi.org/10.3389/fpsyt.2022.848427 kostenfrei https://doaj.org/article/fda0ee3d5a4d449aa593d3a2e1fdb259 kostenfrei https://www.frontiersin.org/articles/10.3389/fpsyt.2022.848427/full kostenfrei https://doaj.org/toc/1664-0640 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2022
allfieldsGer	10.3389/fpsyt.2022.848427 doi (DE-627)DOAJ04652097X (DE-599)DOAJfda0ee3d5a4d449aa593d3a2e1fdb259 DE-627 ger DE-627 rakwb eng RC435-571 Zugui Wu verfasserin aut The Effects of Patient Education on Psychological Status and Clinical Outcomes in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier BackgroundRheumatoid arthritis (RA) is a common systemic inflammatory autoimmune disease. The disease has a serious impact on mental health and requires more effective non-pharmacological interventions.ObjectiveThis study aims to systematically evaluate the effectiveness of patient education on psychological status and clinical outcomes in rheumatoid arthritis.MethodsThis systematic review and meta-analysis was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PubMed, Cochrane Library, EMBASE database, and Web of Science database were screened for articles published until November 2, 2021. Randomized controlled trials (RCTs) of patient education for RA were included. Outcomes measures included pain, physical function, disease activity, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), anxiety, depression, Arthritis Self-Efficacy (pain, other symptoms, total), and General health. For each outcome, standardized mean differences or mean differences and 95% confidence intervals (CIs) were calculated.ResultsA total of 24 RCTs (n = 2,276) were included according to the inclusion and exclusion criteria. Meta-analysis revealed a statistically significant overall effect in favor of patient education for physical function [SMD = −0.52, 95% CI (−0.96, −0.08), I2 = 93%, P = 0.02], disease activity [SMD = −1.97, 95% CI (−3.24, −0.71), I2 = 97%, P = 0.002], ASE (pain) [SMD = −1.24, 95% CI (−2.05, −0.43), I2 = 95%, P = 0.003], ASE (other symptoms) [SMD = −0.25, 95% CI (−0.41, −0.09), I2 = 25%, P = 0.002], ASE (total) [SMD = −0.67, 95% CI (−1.30, −0.05), I2 = 90%, P = 0.03], and general health [SMD = −1.11, 95% CI (−1.36, −0.86), I2 = 96%, P < 0.00001]. No effects were found for anxiety [SMD = 0.17, 95% CI (−0.64, 0.98), I2 = 82%, P = 0.68], depression [SMD = −0.18, 95% CI (−0.52, 0.15), I2 = 52%, P = 0.28], pain [SMD = −0.37, 95% CI (−0.80, 0.05), I2 = 89%, P = 0.08], and CRP [SMD = −0.27, 95% CI (−0.57, 0.02), I2 = 0%, P = 0.07].ConclusionsPatient education may be effective in improving clinical outcomes and psychological status in patients with rheumatoid arthritis. Considering the methodological limitations of the included RCTs, more high-quality and large-sample RCTs are needed to confirm this conclusion in the future.Systematic Review Registrationhttp://www.crd.york.ac.uk/prospero, identifier: CRD42021250607. patient education psychotherapy rheumatoid arthritis meta-analysis systematic review Psychiatry Yue Zhu verfasserin aut Yi Wang verfasserin aut Rui Zhou verfasserin aut Xiangling Ye verfasserin aut Zehua Chen verfasserin aut Congcong Li verfasserin aut Junyi Li verfasserin aut Zixuan Ye verfasserin aut Zhenbang Wang verfasserin aut Wengang Liu verfasserin aut Wengang Liu verfasserin aut Xuemeng Xu verfasserin aut Xuemeng Xu verfasserin aut In Frontiers in Psychiatry Frontiers Media S.A., 2010 13(2022) (DE-627)631498796 (DE-600)2564218-2 16640640 nnns volume:13 year:2022 https://doi.org/10.3389/fpsyt.2022.848427 kostenfrei https://doaj.org/article/fda0ee3d5a4d449aa593d3a2e1fdb259 kostenfrei https://www.frontiersin.org/articles/10.3389/fpsyt.2022.848427/full kostenfrei https://doaj.org/toc/1664-0640 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2022
allfieldsSound	10.3389/fpsyt.2022.848427 doi (DE-627)DOAJ04652097X (DE-599)DOAJfda0ee3d5a4d449aa593d3a2e1fdb259 DE-627 ger DE-627 rakwb eng RC435-571 Zugui Wu verfasserin aut The Effects of Patient Education on Psychological Status and Clinical Outcomes in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier BackgroundRheumatoid arthritis (RA) is a common systemic inflammatory autoimmune disease. The disease has a serious impact on mental health and requires more effective non-pharmacological interventions.ObjectiveThis study aims to systematically evaluate the effectiveness of patient education on psychological status and clinical outcomes in rheumatoid arthritis.MethodsThis systematic review and meta-analysis was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PubMed, Cochrane Library, EMBASE database, and Web of Science database were screened for articles published until November 2, 2021. Randomized controlled trials (RCTs) of patient education for RA were included. Outcomes measures included pain, physical function, disease activity, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), anxiety, depression, Arthritis Self-Efficacy (pain, other symptoms, total), and General health. For each outcome, standardized mean differences or mean differences and 95% confidence intervals (CIs) were calculated.ResultsA total of 24 RCTs (n = 2,276) were included according to the inclusion and exclusion criteria. Meta-analysis revealed a statistically significant overall effect in favor of patient education for physical function [SMD = −0.52, 95% CI (−0.96, −0.08), I2 = 93%, P = 0.02], disease activity [SMD = −1.97, 95% CI (−3.24, −0.71), I2 = 97%, P = 0.002], ASE (pain) [SMD = −1.24, 95% CI (−2.05, −0.43), I2 = 95%, P = 0.003], ASE (other symptoms) [SMD = −0.25, 95% CI (−0.41, −0.09), I2 = 25%, P = 0.002], ASE (total) [SMD = −0.67, 95% CI (−1.30, −0.05), I2 = 90%, P = 0.03], and general health [SMD = −1.11, 95% CI (−1.36, −0.86), I2 = 96%, P < 0.00001]. No effects were found for anxiety [SMD = 0.17, 95% CI (−0.64, 0.98), I2 = 82%, P = 0.68], depression [SMD = −0.18, 95% CI (−0.52, 0.15), I2 = 52%, P = 0.28], pain [SMD = −0.37, 95% CI (−0.80, 0.05), I2 = 89%, P = 0.08], and CRP [SMD = −0.27, 95% CI (−0.57, 0.02), I2 = 0%, P = 0.07].ConclusionsPatient education may be effective in improving clinical outcomes and psychological status in patients with rheumatoid arthritis. Considering the methodological limitations of the included RCTs, more high-quality and large-sample RCTs are needed to confirm this conclusion in the future.Systematic Review Registrationhttp://www.crd.york.ac.uk/prospero, identifier: CRD42021250607. patient education psychotherapy rheumatoid arthritis meta-analysis systematic review Psychiatry Yue Zhu verfasserin aut Yi Wang verfasserin aut Rui Zhou verfasserin aut Xiangling Ye verfasserin aut Zehua Chen verfasserin aut Congcong Li verfasserin aut Junyi Li verfasserin aut Zixuan Ye verfasserin aut Zhenbang Wang verfasserin aut Wengang Liu verfasserin aut Wengang Liu verfasserin aut Xuemeng Xu verfasserin aut Xuemeng Xu verfasserin aut In Frontiers in Psychiatry Frontiers Media S.A., 2010 13(2022) (DE-627)631498796 (DE-600)2564218-2 16640640 nnns volume:13 year:2022 https://doi.org/10.3389/fpsyt.2022.848427 kostenfrei https://doaj.org/article/fda0ee3d5a4d449aa593d3a2e1fdb259 kostenfrei https://www.frontiersin.org/articles/10.3389/fpsyt.2022.848427/full kostenfrei https://doaj.org/toc/1664-0640 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2022
language	English
source	In Frontiers in Psychiatry 13(2022) volume:13 year:2022
sourceStr	In Frontiers in Psychiatry 13(2022) volume:13 year:2022
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	patient education psychotherapy rheumatoid arthritis meta-analysis systematic review Psychiatry
isfreeaccess_bool	true
container_title	Frontiers in Psychiatry
authorswithroles_txt_mv	Zugui Wu @@aut@@ Yue Zhu @@aut@@ Yi Wang @@aut@@ Rui Zhou @@aut@@ Xiangling Ye @@aut@@ Zehua Chen @@aut@@ Congcong Li @@aut@@ Junyi Li @@aut@@ Zixuan Ye @@aut@@ Zhenbang Wang @@aut@@ Wengang Liu @@aut@@ Xuemeng Xu @@aut@@
publishDateDaySort_date	2022-01-01T00:00:00Z
hierarchy_top_id	631498796
id	DOAJ04652097X
language_de	englisch
fullrecord	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ04652097X</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230308111209.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230227s2022 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.3389/fpsyt.2022.848427</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ04652097X</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJfda0ee3d5a4d449aa593d3a2e1fdb259</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RC435-571</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Zugui Wu</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="4"><subfield code="a">The Effects of Patient Education on Psychological Status and Clinical Outcomes in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2022</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">BackgroundRheumatoid arthritis (RA) is a common systemic inflammatory autoimmune disease. The disease has a serious impact on mental health and requires more effective non-pharmacological interventions.ObjectiveThis study aims to systematically evaluate the effectiveness of patient education on psychological status and clinical outcomes in rheumatoid arthritis.MethodsThis systematic review and meta-analysis was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PubMed, Cochrane Library, EMBASE database, and Web of Science database were screened for articles published until November 2, 2021. Randomized controlled trials (RCTs) of patient education for RA were included. Outcomes measures included pain, physical function, disease activity, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), anxiety, depression, Arthritis Self-Efficacy (pain, other symptoms, total), and General health. For each outcome, standardized mean differences or mean differences and 95% confidence intervals (CIs) were calculated.ResultsA total of 24 RCTs (n = 2,276) were included according to the inclusion and exclusion criteria. Meta-analysis revealed a statistically significant overall effect in favor of patient education for physical function [SMD = −0.52, 95% CI (−0.96, −0.08), I2 = 93%, P = 0.02], disease activity [SMD = −1.97, 95% CI (−3.24, −0.71), I2 = 97%, P = 0.002], ASE (pain) [SMD = −1.24, 95% CI (−2.05, −0.43), I2 = 95%, P = 0.003], ASE (other symptoms) [SMD = −0.25, 95% CI (−0.41, −0.09), I2 = 25%, P = 0.002], ASE (total) [SMD = −0.67, 95% CI (−1.30, −0.05), I2 = 90%, P = 0.03], and general health [SMD = −1.11, 95% CI (−1.36, −0.86), I2 = 96%, P &lt; 0.00001]. No effects were found for anxiety [SMD = 0.17, 95% CI (−0.64, 0.98), I2 = 82%, P = 0.68], depression [SMD = −0.18, 95% CI (−0.52, 0.15), I2 = 52%, P = 0.28], pain [SMD = −0.37, 95% CI (−0.80, 0.05), I2 = 89%, P = 0.08], and CRP [SMD = −0.27, 95% CI (−0.57, 0.02), I2 = 0%, P = 0.07].ConclusionsPatient education may be effective in improving clinical outcomes and psychological status in patients with rheumatoid arthritis. 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callnumber-first	R - Medicine
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spellingShingle	Zugui Wu misc RC435-571 misc patient education misc psychotherapy misc rheumatoid arthritis misc meta-analysis misc systematic review misc Psychiatry The Effects of Patient Education on Psychological Status and Clinical Outcomes in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis
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topic_title	RC435-571 The Effects of Patient Education on Psychological Status and Clinical Outcomes in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis patient education psychotherapy rheumatoid arthritis meta-analysis systematic review
topic	misc RC435-571 misc patient education misc psychotherapy misc rheumatoid arthritis misc meta-analysis misc systematic review misc Psychiatry
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title	The Effects of Patient Education on Psychological Status and Clinical Outcomes in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis
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title_full	The Effects of Patient Education on Psychological Status and Clinical Outcomes in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis
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author_browse	Zugui Wu Yue Zhu Yi Wang Rui Zhou Xiangling Ye Zehua Chen Congcong Li Junyi Li Zixuan Ye Zhenbang Wang Wengang Liu Xuemeng Xu
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title_sort	effects of patient education on psychological status and clinical outcomes in rheumatoid arthritis: a systematic review and meta-analysis
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title_auth	The Effects of Patient Education on Psychological Status and Clinical Outcomes in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis
abstract	BackgroundRheumatoid arthritis (RA) is a common systemic inflammatory autoimmune disease. The disease has a serious impact on mental health and requires more effective non-pharmacological interventions.ObjectiveThis study aims to systematically evaluate the effectiveness of patient education on psychological status and clinical outcomes in rheumatoid arthritis.MethodsThis systematic review and meta-analysis was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PubMed, Cochrane Library, EMBASE database, and Web of Science database were screened for articles published until November 2, 2021. Randomized controlled trials (RCTs) of patient education for RA were included. Outcomes measures included pain, physical function, disease activity, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), anxiety, depression, Arthritis Self-Efficacy (pain, other symptoms, total), and General health. For each outcome, standardized mean differences or mean differences and 95% confidence intervals (CIs) were calculated.ResultsA total of 24 RCTs (n = 2,276) were included according to the inclusion and exclusion criteria. Meta-analysis revealed a statistically significant overall effect in favor of patient education for physical function [SMD = −0.52, 95% CI (−0.96, −0.08), I2 = 93%, P = 0.02], disease activity [SMD = −1.97, 95% CI (−3.24, −0.71), I2 = 97%, P = 0.002], ASE (pain) [SMD = −1.24, 95% CI (−2.05, −0.43), I2 = 95%, P = 0.003], ASE (other symptoms) [SMD = −0.25, 95% CI (−0.41, −0.09), I2 = 25%, P = 0.002], ASE (total) [SMD = −0.67, 95% CI (−1.30, −0.05), I2 = 90%, P = 0.03], and general health [SMD = −1.11, 95% CI (−1.36, −0.86), I2 = 96%, P < 0.00001]. No effects were found for anxiety [SMD = 0.17, 95% CI (−0.64, 0.98), I2 = 82%, P = 0.68], depression [SMD = −0.18, 95% CI (−0.52, 0.15), I2 = 52%, P = 0.28], pain [SMD = −0.37, 95% CI (−0.80, 0.05), I2 = 89%, P = 0.08], and CRP [SMD = −0.27, 95% CI (−0.57, 0.02), I2 = 0%, P = 0.07].ConclusionsPatient education may be effective in improving clinical outcomes and psychological status in patients with rheumatoid arthritis. Considering the methodological limitations of the included RCTs, more high-quality and large-sample RCTs are needed to confirm this conclusion in the future.Systematic Review Registrationhttp://www.crd.york.ac.uk/prospero, identifier: CRD42021250607.
abstractGer	BackgroundRheumatoid arthritis (RA) is a common systemic inflammatory autoimmune disease. The disease has a serious impact on mental health and requires more effective non-pharmacological interventions.ObjectiveThis study aims to systematically evaluate the effectiveness of patient education on psychological status and clinical outcomes in rheumatoid arthritis.MethodsThis systematic review and meta-analysis was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PubMed, Cochrane Library, EMBASE database, and Web of Science database were screened for articles published until November 2, 2021. Randomized controlled trials (RCTs) of patient education for RA were included. Outcomes measures included pain, physical function, disease activity, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), anxiety, depression, Arthritis Self-Efficacy (pain, other symptoms, total), and General health. For each outcome, standardized mean differences or mean differences and 95% confidence intervals (CIs) were calculated.ResultsA total of 24 RCTs (n = 2,276) were included according to the inclusion and exclusion criteria. Meta-analysis revealed a statistically significant overall effect in favor of patient education for physical function [SMD = −0.52, 95% CI (−0.96, −0.08), I2 = 93%, P = 0.02], disease activity [SMD = −1.97, 95% CI (−3.24, −0.71), I2 = 97%, P = 0.002], ASE (pain) [SMD = −1.24, 95% CI (−2.05, −0.43), I2 = 95%, P = 0.003], ASE (other symptoms) [SMD = −0.25, 95% CI (−0.41, −0.09), I2 = 25%, P = 0.002], ASE (total) [SMD = −0.67, 95% CI (−1.30, −0.05), I2 = 90%, P = 0.03], and general health [SMD = −1.11, 95% CI (−1.36, −0.86), I2 = 96%, P < 0.00001]. No effects were found for anxiety [SMD = 0.17, 95% CI (−0.64, 0.98), I2 = 82%, P = 0.68], depression [SMD = −0.18, 95% CI (−0.52, 0.15), I2 = 52%, P = 0.28], pain [SMD = −0.37, 95% CI (−0.80, 0.05), I2 = 89%, P = 0.08], and CRP [SMD = −0.27, 95% CI (−0.57, 0.02), I2 = 0%, P = 0.07].ConclusionsPatient education may be effective in improving clinical outcomes and psychological status in patients with rheumatoid arthritis. Considering the methodological limitations of the included RCTs, more high-quality and large-sample RCTs are needed to confirm this conclusion in the future.Systematic Review Registrationhttp://www.crd.york.ac.uk/prospero, identifier: CRD42021250607.
abstract_unstemmed	BackgroundRheumatoid arthritis (RA) is a common systemic inflammatory autoimmune disease. The disease has a serious impact on mental health and requires more effective non-pharmacological interventions.ObjectiveThis study aims to systematically evaluate the effectiveness of patient education on psychological status and clinical outcomes in rheumatoid arthritis.MethodsThis systematic review and meta-analysis was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PubMed, Cochrane Library, EMBASE database, and Web of Science database were screened for articles published until November 2, 2021. Randomized controlled trials (RCTs) of patient education for RA were included. Outcomes measures included pain, physical function, disease activity, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), anxiety, depression, Arthritis Self-Efficacy (pain, other symptoms, total), and General health. For each outcome, standardized mean differences or mean differences and 95% confidence intervals (CIs) were calculated.ResultsA total of 24 RCTs (n = 2,276) were included according to the inclusion and exclusion criteria. Meta-analysis revealed a statistically significant overall effect in favor of patient education for physical function [SMD = −0.52, 95% CI (−0.96, −0.08), I2 = 93%, P = 0.02], disease activity [SMD = −1.97, 95% CI (−3.24, −0.71), I2 = 97%, P = 0.002], ASE (pain) [SMD = −1.24, 95% CI (−2.05, −0.43), I2 = 95%, P = 0.003], ASE (other symptoms) [SMD = −0.25, 95% CI (−0.41, −0.09), I2 = 25%, P = 0.002], ASE (total) [SMD = −0.67, 95% CI (−1.30, −0.05), I2 = 90%, P = 0.03], and general health [SMD = −1.11, 95% CI (−1.36, −0.86), I2 = 96%, P < 0.00001]. No effects were found for anxiety [SMD = 0.17, 95% CI (−0.64, 0.98), I2 = 82%, P = 0.68], depression [SMD = −0.18, 95% CI (−0.52, 0.15), I2 = 52%, P = 0.28], pain [SMD = −0.37, 95% CI (−0.80, 0.05), I2 = 89%, P = 0.08], and CRP [SMD = −0.27, 95% CI (−0.57, 0.02), I2 = 0%, P = 0.07].ConclusionsPatient education may be effective in improving clinical outcomes and psychological status in patients with rheumatoid arthritis. Considering the methodological limitations of the included RCTs, more high-quality and large-sample RCTs are needed to confirm this conclusion in the future.Systematic Review Registrationhttp://www.crd.york.ac.uk/prospero, identifier: CRD42021250607.
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title_short	The Effects of Patient Education on Psychological Status and Clinical Outcomes in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis
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The disease has a serious impact on mental health and requires more effective non-pharmacological interventions.ObjectiveThis study aims to systematically evaluate the effectiveness of patient education on psychological status and clinical outcomes in rheumatoid arthritis.MethodsThis systematic review and meta-analysis was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PubMed, Cochrane Library, EMBASE database, and Web of Science database were screened for articles published until November 2, 2021. Randomized controlled trials (RCTs) of patient education for RA were included. Outcomes measures included pain, physical function, disease activity, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), anxiety, depression, Arthritis Self-Efficacy (pain, other symptoms, total), and General health. For each outcome, standardized mean differences or mean differences and 95% confidence intervals (CIs) were calculated.ResultsA total of 24 RCTs (n = 2,276) were included according to the inclusion and exclusion criteria. Meta-analysis revealed a statistically significant overall effect in favor of patient education for physical function [SMD = −0.52, 95% CI (−0.96, −0.08), I2 = 93%, P = 0.02], disease activity [SMD = −1.97, 95% CI (−3.24, −0.71), I2 = 97%, P = 0.002], ASE (pain) [SMD = −1.24, 95% CI (−2.05, −0.43), I2 = 95%, P = 0.003], ASE (other symptoms) [SMD = −0.25, 95% CI (−0.41, −0.09), I2 = 25%, P = 0.002], ASE (total) [SMD = −0.67, 95% CI (−1.30, −0.05), I2 = 90%, P = 0.03], and general health [SMD = −1.11, 95% CI (−1.36, −0.86), I2 = 96%, P &lt; 0.00001]. No effects were found for anxiety [SMD = 0.17, 95% CI (−0.64, 0.98), I2 = 82%, P = 0.68], depression [SMD = −0.18, 95% CI (−0.52, 0.15), I2 = 52%, P = 0.28], pain [SMD = −0.37, 95% CI (−0.80, 0.05), I2 = 89%, P = 0.08], and CRP [SMD = −0.27, 95% CI (−0.57, 0.02), I2 = 0%, P = 0.07].ConclusionsPatient education may be effective in improving clinical outcomes and psychological status in patients with rheumatoid arthritis. Considering the methodological limitations of the included RCTs, more high-quality and large-sample RCTs are needed to confirm this conclusion in the future.Systematic Review Registrationhttp://www.crd.york.ac.uk/prospero, identifier: CRD42021250607.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">patient education</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">psychotherapy</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">rheumatoid arthritis</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">meta-analysis</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">systematic review</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Psychiatry</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Yue Zhu</subfield><subfield code="e">verfasserin</subfield><subfield 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The Effects of Patient Education on Psychological Status and Clinical Outcomes in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis

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