A review of structural neuroimaging in schizophrenia: from connectivity to connectomics

In patients with schizophrenia neuroimaging studies have revealed global differences with some brain regions showing focal abnormalities. Examining neurocircuitry, diffusion-weighted imaging studies have identified altered structural integrity of white matter in frontal and temporal brain regions an...
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Autor*in:	Anne L Wheeler [verfasserIn] Aristotle N Voineskos [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2014

Schlagwörter:	Diffusion Tensor Imaging Magnetic Resonance Imaging Schizophrenia connectivity white matter connectomics

Übergeordnetes Werk:	In: Frontiers in Human Neuroscience - Frontiers Media S.A., 2008, 8(2014)
Übergeordnetes Werk:	volume:8 ; year:2014

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3389/fnhum.2014.00653

Katalog-ID:	DOAJ046743456

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source	In Frontiers in Human Neuroscience 8(2014) volume:8 year:2014
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topic_facet	Diffusion Tensor Imaging Magnetic Resonance Imaging Schizophrenia connectivity white matter connectomics Neurosciences. Biological psychiatry. Neuropsychiatry
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callnumber-first	R - Medicine
author	Anne L Wheeler
spellingShingle	Anne L Wheeler misc RC321-571 misc Diffusion Tensor Imaging misc Magnetic Resonance Imaging misc Schizophrenia misc connectivity misc white matter misc connectomics misc Neurosciences. Biological psychiatry. Neuropsychiatry A review of structural neuroimaging in schizophrenia: from connectivity to connectomics
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topic_title	RC321-571 A review of structural neuroimaging in schizophrenia: from connectivity to connectomics Diffusion Tensor Imaging Magnetic Resonance Imaging Schizophrenia connectivity white matter connectomics
topic	misc RC321-571 misc Diffusion Tensor Imaging misc Magnetic Resonance Imaging misc Schizophrenia misc connectivity misc white matter misc connectomics misc Neurosciences. Biological psychiatry. Neuropsychiatry
topic_unstemmed	misc RC321-571 misc Diffusion Tensor Imaging misc Magnetic Resonance Imaging misc Schizophrenia misc connectivity misc white matter misc connectomics misc Neurosciences. Biological psychiatry. Neuropsychiatry
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title	A review of structural neuroimaging in schizophrenia: from connectivity to connectomics
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title_auth	A review of structural neuroimaging in schizophrenia: from connectivity to connectomics
abstract	In patients with schizophrenia neuroimaging studies have revealed global differences with some brain regions showing focal abnormalities. Examining neurocircuitry, diffusion-weighted imaging studies have identified altered structural integrity of white matter in frontal and temporal brain regions and tracts such as the cingulum bundles, uncinate fasciculi and corpus callosum associated with the illness. Furthermore, structural co-variance analyses have revealed altered structural relationships among regional morphology in the thalamus, frontal, temporal and parietal cortices in schizophrenia patients. The distributed nature of these abnormalities in schizophrenia suggests that multiple brain circuits are impaired, a neural feature that may be better addressed with network level analyses. However, even with the advent of these newer analyses, a large amount of variability in findings remains, likely partially due to the considerable heterogeneity of this disorder.
abstractGer	In patients with schizophrenia neuroimaging studies have revealed global differences with some brain regions showing focal abnormalities. Examining neurocircuitry, diffusion-weighted imaging studies have identified altered structural integrity of white matter in frontal and temporal brain regions and tracts such as the cingulum bundles, uncinate fasciculi and corpus callosum associated with the illness. Furthermore, structural co-variance analyses have revealed altered structural relationships among regional morphology in the thalamus, frontal, temporal and parietal cortices in schizophrenia patients. The distributed nature of these abnormalities in schizophrenia suggests that multiple brain circuits are impaired, a neural feature that may be better addressed with network level analyses. However, even with the advent of these newer analyses, a large amount of variability in findings remains, likely partially due to the considerable heterogeneity of this disorder.
abstract_unstemmed	In patients with schizophrenia neuroimaging studies have revealed global differences with some brain regions showing focal abnormalities. Examining neurocircuitry, diffusion-weighted imaging studies have identified altered structural integrity of white matter in frontal and temporal brain regions and tracts such as the cingulum bundles, uncinate fasciculi and corpus callosum associated with the illness. Furthermore, structural co-variance analyses have revealed altered structural relationships among regional morphology in the thalamus, frontal, temporal and parietal cortices in schizophrenia patients. The distributed nature of these abnormalities in schizophrenia suggests that multiple brain circuits are impaired, a neural feature that may be better addressed with network level analyses. However, even with the advent of these newer analyses, a large amount of variability in findings remains, likely partially due to the considerable heterogeneity of this disorder.
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A review of structural neuroimaging in schizophrenia: from connectivity to connectomics

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Vorhandene Bände

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