Assessment of Unsuspected Exposure to Drugs of Abuse in Children from a Mediterranean City by Hair Testing

Hair testing was used to investigate the prevalence of unsuspected exposure to drugs of abuse in a group of children presenting to an urban paediatric emergency department without suggestive signs or symptoms. Hair samples were obtained from 114 children between 24 months and 10 years of age attendi...
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Gespeichert in:

Autor*in:	Simona Pichini [verfasserIn] Oscar Garcia-Algar [verfasserIn] Airam Alvarez [verfasserIn] Massimo Gottardi [verfasserIn] Emilia Marchei [verfasserIn] Fiorenza Svaizer [verfasserIn] Manuela Pellegrini [verfasserIn] Maria Concetta Rotolo [verfasserIn] Roberta Pacifici [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2014

Schlagwörter:	hair testing drugs of abuse children unsuspected exposure

Übergeordnetes Werk:	In: International Journal of Environmental Research and Public Health - MDPI AG, 2005, 11(2014), 2, Seite 2288-2298
Übergeordnetes Werk:	volume:11 ; year:2014 ; number:2 ; pages:2288-2298

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/ijerph110202288

Katalog-ID:	DOAJ047089105

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allfields	10.3390/ijerph110202288 doi (DE-627)DOAJ047089105 (DE-599)DOAJ9834304102c346a480a75554fe35e4e7 DE-627 ger DE-627 rakwb eng Simona Pichini verfasserin aut Assessment of Unsuspected Exposure to Drugs of Abuse in Children from a Mediterranean City by Hair Testing 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Hair testing was used to investigate the prevalence of unsuspected exposure to drugs of abuse in a group of children presenting to an urban paediatric emergency department without suggestive signs or symptoms. Hair samples were obtained from 114 children between 24 months and 10 years of age attending the emergency room of Hospital del Mar in Barcelona, Spain. Hair samples from the accompanying parent were also collected. The samples were analyzed for the presence of opiates, cocaine, amphetamines, and cannabinoids by ultra-performance liquid chromatography-tandem mass spectrometry. Parental sociodemographics and possible drug of abuse history were recorded. Hair samples from twenty-three children (20.1%) were positive for cocaine (concentration range 0.15–3.81 ng/mg hair), those of thirteen children (11.4%) to cannabinoids (D9-THC concentration range 0.05–0.54 ng/mg hair), with four samples positive to codeine (0.1–0.25 ng/mg hair), one positive for 2.09 ng methadone per mg hair and one to 6-MAM (0.42 ng/mg hair) and morphine (0. 15 ng/mg hair) . In 69.5 and 69.2% of the positive cocaine and cannabinoids cases respectively, drugs was also found in the hair of accompanying parent. Parental sociodemographics were not associated with children exposure to drugs of abuse. However, the behavioural patterns with potential harmful effects for the child’s health (e.g., tobacco smoking, cannabis, benzodiazepines and/or antidepressants use) were significantly higher in the parents of exposed children. In the light of the obtained results (28% overall children exposure to drugs of abuse) and in agreement with 2009 unsuspected 23% cocaine exposure in pre-school children from the same hospital, we support general hair screening to disclose exposure to drugs of abuse in children from risky environments to provide the basis for specific social and health interventions. hair testing drugs of abuse children unsuspected exposure Medicine R Oscar Garcia-Algar verfasserin aut Airam Alvarez verfasserin aut Massimo Gottardi verfasserin aut Emilia Marchei verfasserin aut Fiorenza Svaizer verfasserin aut Manuela Pellegrini verfasserin aut Maria Concetta Rotolo verfasserin aut Roberta Pacifici verfasserin aut In International Journal of Environmental Research and Public Health MDPI AG, 2005 11(2014), 2, Seite 2288-2298 (DE-627)477992463 (DE-600)2175195-X 16604601 nnns volume:11 year:2014 number:2 pages:2288-2298 https://doi.org/10.3390/ijerph110202288 kostenfrei https://doaj.org/article/9834304102c346a480a75554fe35e4e7 kostenfrei http://www.mdpi.com/1660-4601/11/2/2288 kostenfrei https://doaj.org/toc/1660-4601 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2153 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2014 2 2288-2298
spelling	10.3390/ijerph110202288 doi (DE-627)DOAJ047089105 (DE-599)DOAJ9834304102c346a480a75554fe35e4e7 DE-627 ger DE-627 rakwb eng Simona Pichini verfasserin aut Assessment of Unsuspected Exposure to Drugs of Abuse in Children from a Mediterranean City by Hair Testing 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Hair testing was used to investigate the prevalence of unsuspected exposure to drugs of abuse in a group of children presenting to an urban paediatric emergency department without suggestive signs or symptoms. Hair samples were obtained from 114 children between 24 months and 10 years of age attending the emergency room of Hospital del Mar in Barcelona, Spain. Hair samples from the accompanying parent were also collected. The samples were analyzed for the presence of opiates, cocaine, amphetamines, and cannabinoids by ultra-performance liquid chromatography-tandem mass spectrometry. Parental sociodemographics and possible drug of abuse history were recorded. Hair samples from twenty-three children (20.1%) were positive for cocaine (concentration range 0.15–3.81 ng/mg hair), those of thirteen children (11.4%) to cannabinoids (D9-THC concentration range 0.05–0.54 ng/mg hair), with four samples positive to codeine (0.1–0.25 ng/mg hair), one positive for 2.09 ng methadone per mg hair and one to 6-MAM (0.42 ng/mg hair) and morphine (0. 15 ng/mg hair) . In 69.5 and 69.2% of the positive cocaine and cannabinoids cases respectively, drugs was also found in the hair of accompanying parent. Parental sociodemographics were not associated with children exposure to drugs of abuse. However, the behavioural patterns with potential harmful effects for the child’s health (e.g., tobacco smoking, cannabis, benzodiazepines and/or antidepressants use) were significantly higher in the parents of exposed children. In the light of the obtained results (28% overall children exposure to drugs of abuse) and in agreement with 2009 unsuspected 23% cocaine exposure in pre-school children from the same hospital, we support general hair screening to disclose exposure to drugs of abuse in children from risky environments to provide the basis for specific social and health interventions. hair testing drugs of abuse children unsuspected exposure Medicine R Oscar Garcia-Algar verfasserin aut Airam Alvarez verfasserin aut Massimo Gottardi verfasserin aut Emilia Marchei verfasserin aut Fiorenza Svaizer verfasserin aut Manuela Pellegrini verfasserin aut Maria Concetta Rotolo verfasserin aut Roberta Pacifici verfasserin aut In International Journal of Environmental Research and Public Health MDPI AG, 2005 11(2014), 2, Seite 2288-2298 (DE-627)477992463 (DE-600)2175195-X 16604601 nnns volume:11 year:2014 number:2 pages:2288-2298 https://doi.org/10.3390/ijerph110202288 kostenfrei https://doaj.org/article/9834304102c346a480a75554fe35e4e7 kostenfrei http://www.mdpi.com/1660-4601/11/2/2288 kostenfrei https://doaj.org/toc/1660-4601 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2153 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2014 2 2288-2298
allfields_unstemmed	10.3390/ijerph110202288 doi (DE-627)DOAJ047089105 (DE-599)DOAJ9834304102c346a480a75554fe35e4e7 DE-627 ger DE-627 rakwb eng Simona Pichini verfasserin aut Assessment of Unsuspected Exposure to Drugs of Abuse in Children from a Mediterranean City by Hair Testing 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Hair testing was used to investigate the prevalence of unsuspected exposure to drugs of abuse in a group of children presenting to an urban paediatric emergency department without suggestive signs or symptoms. Hair samples were obtained from 114 children between 24 months and 10 years of age attending the emergency room of Hospital del Mar in Barcelona, Spain. Hair samples from the accompanying parent were also collected. The samples were analyzed for the presence of opiates, cocaine, amphetamines, and cannabinoids by ultra-performance liquid chromatography-tandem mass spectrometry. Parental sociodemographics and possible drug of abuse history were recorded. Hair samples from twenty-three children (20.1%) were positive for cocaine (concentration range 0.15–3.81 ng/mg hair), those of thirteen children (11.4%) to cannabinoids (D9-THC concentration range 0.05–0.54 ng/mg hair), with four samples positive to codeine (0.1–0.25 ng/mg hair), one positive for 2.09 ng methadone per mg hair and one to 6-MAM (0.42 ng/mg hair) and morphine (0. 15 ng/mg hair) . In 69.5 and 69.2% of the positive cocaine and cannabinoids cases respectively, drugs was also found in the hair of accompanying parent. Parental sociodemographics were not associated with children exposure to drugs of abuse. However, the behavioural patterns with potential harmful effects for the child’s health (e.g., tobacco smoking, cannabis, benzodiazepines and/or antidepressants use) were significantly higher in the parents of exposed children. In the light of the obtained results (28% overall children exposure to drugs of abuse) and in agreement with 2009 unsuspected 23% cocaine exposure in pre-school children from the same hospital, we support general hair screening to disclose exposure to drugs of abuse in children from risky environments to provide the basis for specific social and health interventions. hair testing drugs of abuse children unsuspected exposure Medicine R Oscar Garcia-Algar verfasserin aut Airam Alvarez verfasserin aut Massimo Gottardi verfasserin aut Emilia Marchei verfasserin aut Fiorenza Svaizer verfasserin aut Manuela Pellegrini verfasserin aut Maria Concetta Rotolo verfasserin aut Roberta Pacifici verfasserin aut In International Journal of Environmental Research and Public Health MDPI AG, 2005 11(2014), 2, Seite 2288-2298 (DE-627)477992463 (DE-600)2175195-X 16604601 nnns volume:11 year:2014 number:2 pages:2288-2298 https://doi.org/10.3390/ijerph110202288 kostenfrei https://doaj.org/article/9834304102c346a480a75554fe35e4e7 kostenfrei http://www.mdpi.com/1660-4601/11/2/2288 kostenfrei https://doaj.org/toc/1660-4601 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2153 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2014 2 2288-2298
allfieldsGer	10.3390/ijerph110202288 doi (DE-627)DOAJ047089105 (DE-599)DOAJ9834304102c346a480a75554fe35e4e7 DE-627 ger DE-627 rakwb eng Simona Pichini verfasserin aut Assessment of Unsuspected Exposure to Drugs of Abuse in Children from a Mediterranean City by Hair Testing 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Hair testing was used to investigate the prevalence of unsuspected exposure to drugs of abuse in a group of children presenting to an urban paediatric emergency department without suggestive signs or symptoms. Hair samples were obtained from 114 children between 24 months and 10 years of age attending the emergency room of Hospital del Mar in Barcelona, Spain. Hair samples from the accompanying parent were also collected. The samples were analyzed for the presence of opiates, cocaine, amphetamines, and cannabinoids by ultra-performance liquid chromatography-tandem mass spectrometry. Parental sociodemographics and possible drug of abuse history were recorded. Hair samples from twenty-three children (20.1%) were positive for cocaine (concentration range 0.15–3.81 ng/mg hair), those of thirteen children (11.4%) to cannabinoids (D9-THC concentration range 0.05–0.54 ng/mg hair), with four samples positive to codeine (0.1–0.25 ng/mg hair), one positive for 2.09 ng methadone per mg hair and one to 6-MAM (0.42 ng/mg hair) and morphine (0. 15 ng/mg hair) . In 69.5 and 69.2% of the positive cocaine and cannabinoids cases respectively, drugs was also found in the hair of accompanying parent. Parental sociodemographics were not associated with children exposure to drugs of abuse. However, the behavioural patterns with potential harmful effects for the child’s health (e.g., tobacco smoking, cannabis, benzodiazepines and/or antidepressants use) were significantly higher in the parents of exposed children. In the light of the obtained results (28% overall children exposure to drugs of abuse) and in agreement with 2009 unsuspected 23% cocaine exposure in pre-school children from the same hospital, we support general hair screening to disclose exposure to drugs of abuse in children from risky environments to provide the basis for specific social and health interventions. hair testing drugs of abuse children unsuspected exposure Medicine R Oscar Garcia-Algar verfasserin aut Airam Alvarez verfasserin aut Massimo Gottardi verfasserin aut Emilia Marchei verfasserin aut Fiorenza Svaizer verfasserin aut Manuela Pellegrini verfasserin aut Maria Concetta Rotolo verfasserin aut Roberta Pacifici verfasserin aut In International Journal of Environmental Research and Public Health MDPI AG, 2005 11(2014), 2, Seite 2288-2298 (DE-627)477992463 (DE-600)2175195-X 16604601 nnns volume:11 year:2014 number:2 pages:2288-2298 https://doi.org/10.3390/ijerph110202288 kostenfrei https://doaj.org/article/9834304102c346a480a75554fe35e4e7 kostenfrei http://www.mdpi.com/1660-4601/11/2/2288 kostenfrei https://doaj.org/toc/1660-4601 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2153 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2014 2 2288-2298
allfieldsSound	10.3390/ijerph110202288 doi (DE-627)DOAJ047089105 (DE-599)DOAJ9834304102c346a480a75554fe35e4e7 DE-627 ger DE-627 rakwb eng Simona Pichini verfasserin aut Assessment of Unsuspected Exposure to Drugs of Abuse in Children from a Mediterranean City by Hair Testing 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Hair testing was used to investigate the prevalence of unsuspected exposure to drugs of abuse in a group of children presenting to an urban paediatric emergency department without suggestive signs or symptoms. Hair samples were obtained from 114 children between 24 months and 10 years of age attending the emergency room of Hospital del Mar in Barcelona, Spain. Hair samples from the accompanying parent were also collected. The samples were analyzed for the presence of opiates, cocaine, amphetamines, and cannabinoids by ultra-performance liquid chromatography-tandem mass spectrometry. Parental sociodemographics and possible drug of abuse history were recorded. Hair samples from twenty-three children (20.1%) were positive for cocaine (concentration range 0.15–3.81 ng/mg hair), those of thirteen children (11.4%) to cannabinoids (D9-THC concentration range 0.05–0.54 ng/mg hair), with four samples positive to codeine (0.1–0.25 ng/mg hair), one positive for 2.09 ng methadone per mg hair and one to 6-MAM (0.42 ng/mg hair) and morphine (0. 15 ng/mg hair) . In 69.5 and 69.2% of the positive cocaine and cannabinoids cases respectively, drugs was also found in the hair of accompanying parent. Parental sociodemographics were not associated with children exposure to drugs of abuse. However, the behavioural patterns with potential harmful effects for the child’s health (e.g., tobacco smoking, cannabis, benzodiazepines and/or antidepressants use) were significantly higher in the parents of exposed children. In the light of the obtained results (28% overall children exposure to drugs of abuse) and in agreement with 2009 unsuspected 23% cocaine exposure in pre-school children from the same hospital, we support general hair screening to disclose exposure to drugs of abuse in children from risky environments to provide the basis for specific social and health interventions. hair testing drugs of abuse children unsuspected exposure Medicine R Oscar Garcia-Algar verfasserin aut Airam Alvarez verfasserin aut Massimo Gottardi verfasserin aut Emilia Marchei verfasserin aut Fiorenza Svaizer verfasserin aut Manuela Pellegrini verfasserin aut Maria Concetta Rotolo verfasserin aut Roberta Pacifici verfasserin aut In International Journal of Environmental Research and Public Health MDPI AG, 2005 11(2014), 2, Seite 2288-2298 (DE-627)477992463 (DE-600)2175195-X 16604601 nnns volume:11 year:2014 number:2 pages:2288-2298 https://doi.org/10.3390/ijerph110202288 kostenfrei https://doaj.org/article/9834304102c346a480a75554fe35e4e7 kostenfrei http://www.mdpi.com/1660-4601/11/2/2288 kostenfrei https://doaj.org/toc/1660-4601 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2153 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2014 2 2288-2298
language	English
source	In International Journal of Environmental Research and Public Health 11(2014), 2, Seite 2288-2298 volume:11 year:2014 number:2 pages:2288-2298
sourceStr	In International Journal of Environmental Research and Public Health 11(2014), 2, Seite 2288-2298 volume:11 year:2014 number:2 pages:2288-2298
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authorswithroles_txt_mv	Simona Pichini @@aut@@ Oscar Garcia-Algar @@aut@@ Airam Alvarez @@aut@@ Massimo Gottardi @@aut@@ Emilia Marchei @@aut@@ Fiorenza Svaizer @@aut@@ Manuela Pellegrini @@aut@@ Maria Concetta Rotolo @@aut@@ Roberta Pacifici @@aut@@
publishDateDaySort_date	2014-01-01T00:00:00Z
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author	Simona Pichini
spellingShingle	Simona Pichini misc hair testing misc drugs of abuse misc children misc unsuspected exposure misc Medicine misc R Assessment of Unsuspected Exposure to Drugs of Abuse in Children from a Mediterranean City by Hair Testing
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topic_title	Assessment of Unsuspected Exposure to Drugs of Abuse in Children from a Mediterranean City by Hair Testing hair testing drugs of abuse children unsuspected exposure
topic	misc hair testing misc drugs of abuse misc children misc unsuspected exposure misc Medicine misc R
topic_unstemmed	misc hair testing misc drugs of abuse misc children misc unsuspected exposure misc Medicine misc R
topic_browse	misc hair testing misc drugs of abuse misc children misc unsuspected exposure misc Medicine misc R
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title	Assessment of Unsuspected Exposure to Drugs of Abuse in Children from a Mediterranean City by Hair Testing
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title_full	Assessment of Unsuspected Exposure to Drugs of Abuse in Children from a Mediterranean City by Hair Testing
author_sort	Simona Pichini
journal	International Journal of Environmental Research and Public Health
journalStr	International Journal of Environmental Research and Public Health
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author_browse	Simona Pichini Oscar Garcia-Algar Airam Alvarez Massimo Gottardi Emilia Marchei Fiorenza Svaizer Manuela Pellegrini Maria Concetta Rotolo Roberta Pacifici
container_volume	11
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author-letter	Simona Pichini
doi_str_mv	10.3390/ijerph110202288
author2-role	verfasserin
title_sort	assessment of unsuspected exposure to drugs of abuse in children from a mediterranean city by hair testing
title_auth	Assessment of Unsuspected Exposure to Drugs of Abuse in Children from a Mediterranean City by Hair Testing
abstract	Hair testing was used to investigate the prevalence of unsuspected exposure to drugs of abuse in a group of children presenting to an urban paediatric emergency department without suggestive signs or symptoms. Hair samples were obtained from 114 children between 24 months and 10 years of age attending the emergency room of Hospital del Mar in Barcelona, Spain. Hair samples from the accompanying parent were also collected. The samples were analyzed for the presence of opiates, cocaine, amphetamines, and cannabinoids by ultra-performance liquid chromatography-tandem mass spectrometry. Parental sociodemographics and possible drug of abuse history were recorded. Hair samples from twenty-three children (20.1%) were positive for cocaine (concentration range 0.15–3.81 ng/mg hair), those of thirteen children (11.4%) to cannabinoids (D9-THC concentration range 0.05–0.54 ng/mg hair), with four samples positive to codeine (0.1–0.25 ng/mg hair), one positive for 2.09 ng methadone per mg hair and one to 6-MAM (0.42 ng/mg hair) and morphine (0. 15 ng/mg hair) . In 69.5 and 69.2% of the positive cocaine and cannabinoids cases respectively, drugs was also found in the hair of accompanying parent. Parental sociodemographics were not associated with children exposure to drugs of abuse. However, the behavioural patterns with potential harmful effects for the child’s health (e.g., tobacco smoking, cannabis, benzodiazepines and/or antidepressants use) were significantly higher in the parents of exposed children. In the light of the obtained results (28% overall children exposure to drugs of abuse) and in agreement with 2009 unsuspected 23% cocaine exposure in pre-school children from the same hospital, we support general hair screening to disclose exposure to drugs of abuse in children from risky environments to provide the basis for specific social and health interventions.
abstractGer	Hair testing was used to investigate the prevalence of unsuspected exposure to drugs of abuse in a group of children presenting to an urban paediatric emergency department without suggestive signs or symptoms. Hair samples were obtained from 114 children between 24 months and 10 years of age attending the emergency room of Hospital del Mar in Barcelona, Spain. Hair samples from the accompanying parent were also collected. The samples were analyzed for the presence of opiates, cocaine, amphetamines, and cannabinoids by ultra-performance liquid chromatography-tandem mass spectrometry. Parental sociodemographics and possible drug of abuse history were recorded. Hair samples from twenty-three children (20.1%) were positive for cocaine (concentration range 0.15–3.81 ng/mg hair), those of thirteen children (11.4%) to cannabinoids (D9-THC concentration range 0.05–0.54 ng/mg hair), with four samples positive to codeine (0.1–0.25 ng/mg hair), one positive for 2.09 ng methadone per mg hair and one to 6-MAM (0.42 ng/mg hair) and morphine (0. 15 ng/mg hair) . In 69.5 and 69.2% of the positive cocaine and cannabinoids cases respectively, drugs was also found in the hair of accompanying parent. Parental sociodemographics were not associated with children exposure to drugs of abuse. However, the behavioural patterns with potential harmful effects for the child’s health (e.g., tobacco smoking, cannabis, benzodiazepines and/or antidepressants use) were significantly higher in the parents of exposed children. In the light of the obtained results (28% overall children exposure to drugs of abuse) and in agreement with 2009 unsuspected 23% cocaine exposure in pre-school children from the same hospital, we support general hair screening to disclose exposure to drugs of abuse in children from risky environments to provide the basis for specific social and health interventions.
abstract_unstemmed	Hair testing was used to investigate the prevalence of unsuspected exposure to drugs of abuse in a group of children presenting to an urban paediatric emergency department without suggestive signs or symptoms. Hair samples were obtained from 114 children between 24 months and 10 years of age attending the emergency room of Hospital del Mar in Barcelona, Spain. Hair samples from the accompanying parent were also collected. The samples were analyzed for the presence of opiates, cocaine, amphetamines, and cannabinoids by ultra-performance liquid chromatography-tandem mass spectrometry. Parental sociodemographics and possible drug of abuse history were recorded. Hair samples from twenty-three children (20.1%) were positive for cocaine (concentration range 0.15–3.81 ng/mg hair), those of thirteen children (11.4%) to cannabinoids (D9-THC concentration range 0.05–0.54 ng/mg hair), with four samples positive to codeine (0.1–0.25 ng/mg hair), one positive for 2.09 ng methadone per mg hair and one to 6-MAM (0.42 ng/mg hair) and morphine (0. 15 ng/mg hair) . In 69.5 and 69.2% of the positive cocaine and cannabinoids cases respectively, drugs was also found in the hair of accompanying parent. Parental sociodemographics were not associated with children exposure to drugs of abuse. However, the behavioural patterns with potential harmful effects for the child’s health (e.g., tobacco smoking, cannabis, benzodiazepines and/or antidepressants use) were significantly higher in the parents of exposed children. In the light of the obtained results (28% overall children exposure to drugs of abuse) and in agreement with 2009 unsuspected 23% cocaine exposure in pre-school children from the same hospital, we support general hair screening to disclose exposure to drugs of abuse in children from risky environments to provide the basis for specific social and health interventions.
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container_issue	2
title_short	Assessment of Unsuspected Exposure to Drugs of Abuse in Children from a Mediterranean City by Hair Testing
url	https://doi.org/10.3390/ijerph110202288 https://doaj.org/article/9834304102c346a480a75554fe35e4e7 http://www.mdpi.com/1660-4601/11/2/2288 https://doaj.org/toc/1660-4601
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author2	Oscar Garcia-Algar Airam Alvarez Massimo Gottardi Emilia Marchei Fiorenza Svaizer Manuela Pellegrini Maria Concetta Rotolo Roberta Pacifici
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