Surveillance for Unexplained Deaths and Critical Illnesses

Population-based surveillance for unexplained death and critical illness possibly due to infectious causes (UNEX) was conducted in four U.S. Emerging Infections Program sites (population 7.7 million) from May 1, 1995, to December 31, 1998, to define the incidence, epidemiologic features, and etiolog...
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Autor*in:	Rana A. Hajjeh [verfasserIn] David Relman [verfasserIn] Paul R. Cieslak [verfasserIn] Andre N. Sofair [verfasserIn] Douglas Passaro [verfasserIn] Jennifer Flood [verfasserIn] James Johnson [verfasserIn] Jill K. Hacker [verfasserIn] Wun-Ju Shieh [verfasserIn] R. Michael Hendry [verfasserIn] Simo Nikkari [verfasserIn] Stephen Ladd-Wilson [verfasserIn] James L. Hadler [verfasserIn] Jean Rainbow [verfasserIn] Jordan W. Tappero [verfasserIn] Christopher W. Woods [verfasserIn] Laura Conn [verfasserIn] Sarah Reagan [verfasserIn] Sherif Zaki [verfasserIn] Bradley A. Perkins [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2002

Schlagwörter:	16S polymerase chain reaction emerging infectious diseases unexplained infectious diseases United States

Übergeordnetes Werk:	In: Emerging Infectious Diseases - Centers for Disease Control and Prevention, 2003, 8(2002), 2, Seite 145-153
Übergeordnetes Werk:	volume:8 ; year:2002 ; number:2 ; pages:145-153

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.3201/eid0802.010165

Katalog-ID:	DOAJ047421975

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allfields	10.3201/eid0802.010165 doi (DE-627)DOAJ047421975 (DE-599)DOAJ4aaf882958c04e3c9056321c732b466b DE-627 ger DE-627 rakwb eng RC109-216 Rana A. Hajjeh verfasserin aut Surveillance for Unexplained Deaths and Critical Illnesses 2002 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Population-based surveillance for unexplained death and critical illness possibly due to infectious causes (UNEX) was conducted in four U.S. Emerging Infections Program sites (population 7.7 million) from May 1, 1995, to December 31, 1998, to define the incidence, epidemiologic features, and etiology of this syndrome. A case was defined as death or critical illness in a hospitalized, previously healthy person, 1 to 49 years of age, with infection hallmarks but no cause identified after routine testing. A total of 137 cases were identified (incidence rate 0.5 per 100,000 per year). Patients’ median age was 20 years, 72 (53%) were female, 112 (82%) were white, and 41 (30%) died. The most common clinical presentations were neurologic (29%), respiratory (27%), and cardiac (21%). Infectious causes were identified for 34 cases (28% of the 122 cases with clinical specimens); 23 (68%) were diagnosed by reference serologic tests, and 11 (32%) by polymerase chain reaction-based methods. The UNEX network model would improve U.S. diagnostic capacities and preparedness for emerging infections. 16S polymerase chain reaction emerging infectious diseases unexplained infectious diseases United States Medicine R Infectious and parasitic diseases David Relman verfasserin aut Paul R. Cieslak verfasserin aut Andre N. Sofair verfasserin aut Douglas Passaro verfasserin aut Jennifer Flood verfasserin aut James Johnson verfasserin aut Jill K. Hacker verfasserin aut Wun-Ju Shieh verfasserin aut R. Michael Hendry verfasserin aut Simo Nikkari verfasserin aut Stephen Ladd-Wilson verfasserin aut James L. Hadler verfasserin aut Jean Rainbow verfasserin aut Jordan W. Tappero verfasserin aut Christopher W. Woods verfasserin aut Laura Conn verfasserin aut Sarah Reagan verfasserin aut Sherif Zaki verfasserin aut Bradley A. Perkins verfasserin aut In Emerging Infectious Diseases Centers for Disease Control and Prevention, 2003 8(2002), 2, Seite 145-153 (DE-627)320436217 (DE-600)2004375-2 10806059 nnns volume:8 year:2002 number:2 pages:145-153 https://doi.org/10.3201/eid0802.010165 kostenfrei https://doaj.org/article/4aaf882958c04e3c9056321c732b466b kostenfrei https://wwwnc.cdc.gov/eid/article/8/2/01-0165_article kostenfrei https://doaj.org/toc/1080-6040 Journal toc kostenfrei https://doaj.org/toc/1080-6059 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_252 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2002 2 145-153
spelling	10.3201/eid0802.010165 doi (DE-627)DOAJ047421975 (DE-599)DOAJ4aaf882958c04e3c9056321c732b466b DE-627 ger DE-627 rakwb eng RC109-216 Rana A. Hajjeh verfasserin aut Surveillance for Unexplained Deaths and Critical Illnesses 2002 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Population-based surveillance for unexplained death and critical illness possibly due to infectious causes (UNEX) was conducted in four U.S. Emerging Infections Program sites (population 7.7 million) from May 1, 1995, to December 31, 1998, to define the incidence, epidemiologic features, and etiology of this syndrome. A case was defined as death or critical illness in a hospitalized, previously healthy person, 1 to 49 years of age, with infection hallmarks but no cause identified after routine testing. A total of 137 cases were identified (incidence rate 0.5 per 100,000 per year). Patients’ median age was 20 years, 72 (53%) were female, 112 (82%) were white, and 41 (30%) died. The most common clinical presentations were neurologic (29%), respiratory (27%), and cardiac (21%). Infectious causes were identified for 34 cases (28% of the 122 cases with clinical specimens); 23 (68%) were diagnosed by reference serologic tests, and 11 (32%) by polymerase chain reaction-based methods. The UNEX network model would improve U.S. diagnostic capacities and preparedness for emerging infections. 16S polymerase chain reaction emerging infectious diseases unexplained infectious diseases United States Medicine R Infectious and parasitic diseases David Relman verfasserin aut Paul R. Cieslak verfasserin aut Andre N. Sofair verfasserin aut Douglas Passaro verfasserin aut Jennifer Flood verfasserin aut James Johnson verfasserin aut Jill K. Hacker verfasserin aut Wun-Ju Shieh verfasserin aut R. Michael Hendry verfasserin aut Simo Nikkari verfasserin aut Stephen Ladd-Wilson verfasserin aut James L. Hadler verfasserin aut Jean Rainbow verfasserin aut Jordan W. Tappero verfasserin aut Christopher W. Woods verfasserin aut Laura Conn verfasserin aut Sarah Reagan verfasserin aut Sherif Zaki verfasserin aut Bradley A. Perkins verfasserin aut In Emerging Infectious Diseases Centers for Disease Control and Prevention, 2003 8(2002), 2, Seite 145-153 (DE-627)320436217 (DE-600)2004375-2 10806059 nnns volume:8 year:2002 number:2 pages:145-153 https://doi.org/10.3201/eid0802.010165 kostenfrei https://doaj.org/article/4aaf882958c04e3c9056321c732b466b kostenfrei https://wwwnc.cdc.gov/eid/article/8/2/01-0165_article kostenfrei https://doaj.org/toc/1080-6040 Journal toc kostenfrei https://doaj.org/toc/1080-6059 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_252 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2002 2 145-153
allfields_unstemmed	10.3201/eid0802.010165 doi (DE-627)DOAJ047421975 (DE-599)DOAJ4aaf882958c04e3c9056321c732b466b DE-627 ger DE-627 rakwb eng RC109-216 Rana A. Hajjeh verfasserin aut Surveillance for Unexplained Deaths and Critical Illnesses 2002 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Population-based surveillance for unexplained death and critical illness possibly due to infectious causes (UNEX) was conducted in four U.S. Emerging Infections Program sites (population 7.7 million) from May 1, 1995, to December 31, 1998, to define the incidence, epidemiologic features, and etiology of this syndrome. A case was defined as death or critical illness in a hospitalized, previously healthy person, 1 to 49 years of age, with infection hallmarks but no cause identified after routine testing. A total of 137 cases were identified (incidence rate 0.5 per 100,000 per year). Patients’ median age was 20 years, 72 (53%) were female, 112 (82%) were white, and 41 (30%) died. The most common clinical presentations were neurologic (29%), respiratory (27%), and cardiac (21%). Infectious causes were identified for 34 cases (28% of the 122 cases with clinical specimens); 23 (68%) were diagnosed by reference serologic tests, and 11 (32%) by polymerase chain reaction-based methods. The UNEX network model would improve U.S. diagnostic capacities and preparedness for emerging infections. 16S polymerase chain reaction emerging infectious diseases unexplained infectious diseases United States Medicine R Infectious and parasitic diseases David Relman verfasserin aut Paul R. Cieslak verfasserin aut Andre N. Sofair verfasserin aut Douglas Passaro verfasserin aut Jennifer Flood verfasserin aut James Johnson verfasserin aut Jill K. Hacker verfasserin aut Wun-Ju Shieh verfasserin aut R. Michael Hendry verfasserin aut Simo Nikkari verfasserin aut Stephen Ladd-Wilson verfasserin aut James L. Hadler verfasserin aut Jean Rainbow verfasserin aut Jordan W. Tappero verfasserin aut Christopher W. Woods verfasserin aut Laura Conn verfasserin aut Sarah Reagan verfasserin aut Sherif Zaki verfasserin aut Bradley A. Perkins verfasserin aut In Emerging Infectious Diseases Centers for Disease Control and Prevention, 2003 8(2002), 2, Seite 145-153 (DE-627)320436217 (DE-600)2004375-2 10806059 nnns volume:8 year:2002 number:2 pages:145-153 https://doi.org/10.3201/eid0802.010165 kostenfrei https://doaj.org/article/4aaf882958c04e3c9056321c732b466b kostenfrei https://wwwnc.cdc.gov/eid/article/8/2/01-0165_article kostenfrei https://doaj.org/toc/1080-6040 Journal toc kostenfrei https://doaj.org/toc/1080-6059 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_252 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2002 2 145-153
allfieldsGer	10.3201/eid0802.010165 doi (DE-627)DOAJ047421975 (DE-599)DOAJ4aaf882958c04e3c9056321c732b466b DE-627 ger DE-627 rakwb eng RC109-216 Rana A. Hajjeh verfasserin aut Surveillance for Unexplained Deaths and Critical Illnesses 2002 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Population-based surveillance for unexplained death and critical illness possibly due to infectious causes (UNEX) was conducted in four U.S. Emerging Infections Program sites (population 7.7 million) from May 1, 1995, to December 31, 1998, to define the incidence, epidemiologic features, and etiology of this syndrome. A case was defined as death or critical illness in a hospitalized, previously healthy person, 1 to 49 years of age, with infection hallmarks but no cause identified after routine testing. A total of 137 cases were identified (incidence rate 0.5 per 100,000 per year). Patients’ median age was 20 years, 72 (53%) were female, 112 (82%) were white, and 41 (30%) died. The most common clinical presentations were neurologic (29%), respiratory (27%), and cardiac (21%). Infectious causes were identified for 34 cases (28% of the 122 cases with clinical specimens); 23 (68%) were diagnosed by reference serologic tests, and 11 (32%) by polymerase chain reaction-based methods. The UNEX network model would improve U.S. diagnostic capacities and preparedness for emerging infections. 16S polymerase chain reaction emerging infectious diseases unexplained infectious diseases United States Medicine R Infectious and parasitic diseases David Relman verfasserin aut Paul R. Cieslak verfasserin aut Andre N. Sofair verfasserin aut Douglas Passaro verfasserin aut Jennifer Flood verfasserin aut James Johnson verfasserin aut Jill K. Hacker verfasserin aut Wun-Ju Shieh verfasserin aut R. Michael Hendry verfasserin aut Simo Nikkari verfasserin aut Stephen Ladd-Wilson verfasserin aut James L. Hadler verfasserin aut Jean Rainbow verfasserin aut Jordan W. Tappero verfasserin aut Christopher W. Woods verfasserin aut Laura Conn verfasserin aut Sarah Reagan verfasserin aut Sherif Zaki verfasserin aut Bradley A. Perkins verfasserin aut In Emerging Infectious Diseases Centers for Disease Control and Prevention, 2003 8(2002), 2, Seite 145-153 (DE-627)320436217 (DE-600)2004375-2 10806059 nnns volume:8 year:2002 number:2 pages:145-153 https://doi.org/10.3201/eid0802.010165 kostenfrei https://doaj.org/article/4aaf882958c04e3c9056321c732b466b kostenfrei https://wwwnc.cdc.gov/eid/article/8/2/01-0165_article kostenfrei https://doaj.org/toc/1080-6040 Journal toc kostenfrei https://doaj.org/toc/1080-6059 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_252 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2002 2 145-153
allfieldsSound	10.3201/eid0802.010165 doi (DE-627)DOAJ047421975 (DE-599)DOAJ4aaf882958c04e3c9056321c732b466b DE-627 ger DE-627 rakwb eng RC109-216 Rana A. Hajjeh verfasserin aut Surveillance for Unexplained Deaths and Critical Illnesses 2002 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Population-based surveillance for unexplained death and critical illness possibly due to infectious causes (UNEX) was conducted in four U.S. Emerging Infections Program sites (population 7.7 million) from May 1, 1995, to December 31, 1998, to define the incidence, epidemiologic features, and etiology of this syndrome. A case was defined as death or critical illness in a hospitalized, previously healthy person, 1 to 49 years of age, with infection hallmarks but no cause identified after routine testing. A total of 137 cases were identified (incidence rate 0.5 per 100,000 per year). Patients’ median age was 20 years, 72 (53%) were female, 112 (82%) were white, and 41 (30%) died. The most common clinical presentations were neurologic (29%), respiratory (27%), and cardiac (21%). Infectious causes were identified for 34 cases (28% of the 122 cases with clinical specimens); 23 (68%) were diagnosed by reference serologic tests, and 11 (32%) by polymerase chain reaction-based methods. The UNEX network model would improve U.S. diagnostic capacities and preparedness for emerging infections. 16S polymerase chain reaction emerging infectious diseases unexplained infectious diseases United States Medicine R Infectious and parasitic diseases David Relman verfasserin aut Paul R. Cieslak verfasserin aut Andre N. Sofair verfasserin aut Douglas Passaro verfasserin aut Jennifer Flood verfasserin aut James Johnson verfasserin aut Jill K. Hacker verfasserin aut Wun-Ju Shieh verfasserin aut R. Michael Hendry verfasserin aut Simo Nikkari verfasserin aut Stephen Ladd-Wilson verfasserin aut James L. Hadler verfasserin aut Jean Rainbow verfasserin aut Jordan W. Tappero verfasserin aut Christopher W. Woods verfasserin aut Laura Conn verfasserin aut Sarah Reagan verfasserin aut Sherif Zaki verfasserin aut Bradley A. Perkins verfasserin aut In Emerging Infectious Diseases Centers for Disease Control and Prevention, 2003 8(2002), 2, Seite 145-153 (DE-627)320436217 (DE-600)2004375-2 10806059 nnns volume:8 year:2002 number:2 pages:145-153 https://doi.org/10.3201/eid0802.010165 kostenfrei https://doaj.org/article/4aaf882958c04e3c9056321c732b466b kostenfrei https://wwwnc.cdc.gov/eid/article/8/2/01-0165_article kostenfrei https://doaj.org/toc/1080-6040 Journal toc kostenfrei https://doaj.org/toc/1080-6059 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_252 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2002 2 145-153
language	English
source	In Emerging Infectious Diseases 8(2002), 2, Seite 145-153 volume:8 year:2002 number:2 pages:145-153
sourceStr	In Emerging Infectious Diseases 8(2002), 2, Seite 145-153 volume:8 year:2002 number:2 pages:145-153
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	16S polymerase chain reaction emerging infectious diseases unexplained infectious diseases United States Medicine R Infectious and parasitic diseases
isfreeaccess_bool	true
container_title	Emerging Infectious Diseases
authorswithroles_txt_mv	Rana A. Hajjeh @@aut@@ David Relman @@aut@@ Paul R. Cieslak @@aut@@ Andre N. Sofair @@aut@@ Douglas Passaro @@aut@@ Jennifer Flood @@aut@@ James Johnson @@aut@@ Jill K. Hacker @@aut@@ Wun-Ju Shieh @@aut@@ R. Michael Hendry @@aut@@ Simo Nikkari @@aut@@ Stephen Ladd-Wilson @@aut@@ James L. Hadler @@aut@@ Jean Rainbow @@aut@@ Jordan W. Tappero @@aut@@ Christopher W. Woods @@aut@@ Laura Conn @@aut@@ Sarah Reagan @@aut@@ Sherif Zaki @@aut@@ Bradley A. Perkins @@aut@@
publishDateDaySort_date	2002-01-01T00:00:00Z
hierarchy_top_id	320436217
id	DOAJ047421975
language_de	englisch
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callnumber-first	R - Medicine
author	Rana A. Hajjeh
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topic_title	RC109-216 Surveillance for Unexplained Deaths and Critical Illnesses 16S polymerase chain reaction emerging infectious diseases unexplained infectious diseases United States
topic	misc RC109-216 misc 16S polymerase chain reaction misc emerging infectious diseases misc unexplained infectious diseases misc United States misc Medicine misc R misc Infectious and parasitic diseases
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title	Surveillance for Unexplained Deaths and Critical Illnesses
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title_full	Surveillance for Unexplained Deaths and Critical Illnesses
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title_sort	surveillance for unexplained deaths and critical illnesses
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title_auth	Surveillance for Unexplained Deaths and Critical Illnesses
abstract	Population-based surveillance for unexplained death and critical illness possibly due to infectious causes (UNEX) was conducted in four U.S. Emerging Infections Program sites (population 7.7 million) from May 1, 1995, to December 31, 1998, to define the incidence, epidemiologic features, and etiology of this syndrome. A case was defined as death or critical illness in a hospitalized, previously healthy person, 1 to 49 years of age, with infection hallmarks but no cause identified after routine testing. A total of 137 cases were identified (incidence rate 0.5 per 100,000 per year). Patients’ median age was 20 years, 72 (53%) were female, 112 (82%) were white, and 41 (30%) died. The most common clinical presentations were neurologic (29%), respiratory (27%), and cardiac (21%). Infectious causes were identified for 34 cases (28% of the 122 cases with clinical specimens); 23 (68%) were diagnosed by reference serologic tests, and 11 (32%) by polymerase chain reaction-based methods. The UNEX network model would improve U.S. diagnostic capacities and preparedness for emerging infections.
abstractGer	Population-based surveillance for unexplained death and critical illness possibly due to infectious causes (UNEX) was conducted in four U.S. Emerging Infections Program sites (population 7.7 million) from May 1, 1995, to December 31, 1998, to define the incidence, epidemiologic features, and etiology of this syndrome. A case was defined as death or critical illness in a hospitalized, previously healthy person, 1 to 49 years of age, with infection hallmarks but no cause identified after routine testing. A total of 137 cases were identified (incidence rate 0.5 per 100,000 per year). Patients’ median age was 20 years, 72 (53%) were female, 112 (82%) were white, and 41 (30%) died. The most common clinical presentations were neurologic (29%), respiratory (27%), and cardiac (21%). Infectious causes were identified for 34 cases (28% of the 122 cases with clinical specimens); 23 (68%) were diagnosed by reference serologic tests, and 11 (32%) by polymerase chain reaction-based methods. The UNEX network model would improve U.S. diagnostic capacities and preparedness for emerging infections.
abstract_unstemmed	Population-based surveillance for unexplained death and critical illness possibly due to infectious causes (UNEX) was conducted in four U.S. Emerging Infections Program sites (population 7.7 million) from May 1, 1995, to December 31, 1998, to define the incidence, epidemiologic features, and etiology of this syndrome. A case was defined as death or critical illness in a hospitalized, previously healthy person, 1 to 49 years of age, with infection hallmarks but no cause identified after routine testing. A total of 137 cases were identified (incidence rate 0.5 per 100,000 per year). Patients’ median age was 20 years, 72 (53%) were female, 112 (82%) were white, and 41 (30%) died. The most common clinical presentations were neurologic (29%), respiratory (27%), and cardiac (21%). Infectious causes were identified for 34 cases (28% of the 122 cases with clinical specimens); 23 (68%) were diagnosed by reference serologic tests, and 11 (32%) by polymerase chain reaction-based methods. The UNEX network model would improve U.S. diagnostic capacities and preparedness for emerging infections.
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title_short	Surveillance for Unexplained Deaths and Critical Illnesses
url	https://doi.org/10.3201/eid0802.010165 https://doaj.org/article/4aaf882958c04e3c9056321c732b466b https://wwwnc.cdc.gov/eid/article/8/2/01-0165_article https://doaj.org/toc/1080-6040 https://doaj.org/toc/1080-6059
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