Ionotropic glutamate receptors (iGluRs) of the delta family (GluD1 and GluD2) and synaptogenesis

Glutamate delta-1 (GluD1) and glutamate delta-2 (GluD2) form the delta family of ionotropic glutamate receptors (iGluRs) and are distinct from other (iGluRs) in that they do not exhibit typical agonist-induced ion channel currents. Recent studies have demonstrated a crucial role of the delta recepto...
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Autor*in:	Muhammad Zahid Khan [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2017

Schlagwörter:	iGluRs GluD1 GluD2 Synaptogenesis Autism spectrum disorder (ASD) Schizophrenia (SCZ)

Übergeordnetes Werk:	In: Alexandria Journal of Medicine - Taylor & Francis Group, 2020, 53(2017), 3, Seite 201-206
Übergeordnetes Werk:	volume:53 ; year:2017 ; number:3 ; pages:201-206

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1016/j.ajme.2016.09.003

Katalog-ID:	DOAJ047437448

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author	Muhammad Zahid Khan
spellingShingle	Muhammad Zahid Khan misc iGluRs misc GluD1 misc GluD2 misc Synaptogenesis misc Autism spectrum disorder (ASD) misc Schizophrenia (SCZ) misc Medicine misc R Ionotropic glutamate receptors (iGluRs) of the delta family (GluD1 and GluD2) and synaptogenesis
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topic_title	Ionotropic glutamate receptors (iGluRs) of the delta family (GluD1 and GluD2) and synaptogenesis iGluRs GluD1 GluD2 Synaptogenesis Autism spectrum disorder (ASD) Schizophrenia (SCZ)
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title	Ionotropic glutamate receptors (iGluRs) of the delta family (GluD1 and GluD2) and synaptogenesis
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title_full	Ionotropic glutamate receptors (iGluRs) of the delta family (GluD1 and GluD2) and synaptogenesis
author_sort	Muhammad Zahid Khan
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title_sort	ionotropic glutamate receptors (iglurs) of the delta family (glud1 and glud2) and synaptogenesis
title_auth	Ionotropic glutamate receptors (iGluRs) of the delta family (GluD1 and GluD2) and synaptogenesis
abstract	Glutamate delta-1 (GluD1) and glutamate delta-2 (GluD2) form the delta family of ionotropic glutamate receptors (iGluRs) and are distinct from other (iGluRs) in that they do not exhibit typical agonist-induced ion channel currents. Recent studies have demonstrated a crucial role of the delta receptors in synapse formation by interacting with presynaptic proteins such as Neurexin1. This review presents current knowledge regarding the expression, structure and function of Glu delta receptors (GluD1, GluD2) in brain, focusing on synapse formation, function and dysfunction.
abstractGer	Glutamate delta-1 (GluD1) and glutamate delta-2 (GluD2) form the delta family of ionotropic glutamate receptors (iGluRs) and are distinct from other (iGluRs) in that they do not exhibit typical agonist-induced ion channel currents. Recent studies have demonstrated a crucial role of the delta receptors in synapse formation by interacting with presynaptic proteins such as Neurexin1. This review presents current knowledge regarding the expression, structure and function of Glu delta receptors (GluD1, GluD2) in brain, focusing on synapse formation, function and dysfunction.
abstract_unstemmed	Glutamate delta-1 (GluD1) and glutamate delta-2 (GluD2) form the delta family of ionotropic glutamate receptors (iGluRs) and are distinct from other (iGluRs) in that they do not exhibit typical agonist-induced ion channel currents. Recent studies have demonstrated a crucial role of the delta receptors in synapse formation by interacting with presynaptic proteins such as Neurexin1. This review presents current knowledge regarding the expression, structure and function of Glu delta receptors (GluD1, GluD2) in brain, focusing on synapse formation, function and dysfunction.
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title_short	Ionotropic glutamate receptors (iGluRs) of the delta family (GluD1 and GluD2) and synaptogenesis
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up_date	2024-07-04T01:19:11.243Z
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