Jaffe's kinetic method comparison between isotope dilution mass spectrometry standardized versus nonstandardized method
INTRODUCTION: Serum creatinine is estimated by several methods in different laboratories, having varying degrees of bias and imprecision, leading to different values across the laboratories with the same sample. To reduce the interlaboratory variations in creatinine assay, creatinine standardization...
Ausführliche Beschreibung
Autor*in: |
Girish Konasagara Shanthaveeranna [verfasserIn] Anitha Devanath [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
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2020 |
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Übergeordnetes Werk: |
In: Indian Journal of Health Sciences and Biomedical Research KLEU - Wolters Kluwer Medknow Publications, 2019, 13(2020), 2, Seite 137-139 |
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Übergeordnetes Werk: |
volume:13 ; year:2020 ; number:2 ; pages:137-139 |
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Link aufrufen |
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DOI / URN: |
10.4103/kleuhsj.kleuhsj_39_20 |
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Katalog-ID: |
DOAJ048280283 |
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10.4103/kleuhsj.kleuhsj_39_20 doi (DE-627)DOAJ048280283 (DE-599)DOAJf2ee2275202b4fa699d5df8c38d4c2e6 DE-627 ger DE-627 rakwb eng Girish Konasagara Shanthaveeranna verfasserin aut Jaffe's kinetic method comparison between isotope dilution mass spectrometry standardized versus nonstandardized method 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier INTRODUCTION: Serum creatinine is estimated by several methods in different laboratories, having varying degrees of bias and imprecision, leading to different values across the laboratories with the same sample. To reduce the interlaboratory variations in creatinine assay, creatinine standardization program was established by the National Kidney Disease Education Program Laboratory Working Group and recommended that creatinine calibration should be done with material traceable to an Isotope dilution mass spectrometry (IDMS) reference measurement procedure. AIMS AND OBJECTIVE: To compare the serum creatinine estimated by CRE (calibration nonstandardized IDMS with correction factor) and CRE2 (standardized to IDMS) method. MATERIALS AND METHODS: The study was conducted in a tertiary care hospital as a part of validation of CRE2 method. Two hundred samples were selected from individuals aged between 18 and 60 years with normal serum urea, creatinine, and electrolytes based on the CRE2 method. Further, the sample is estimated for serum creatinine by CRE method on the same instrument with a correction factor (Siemens Dimension RXL with LM). Descriptive statistics and Bland–Altman analysis were used to describe the population and check for agreement between the methods. RESULTS AND CONCLUSION: The average serum creatinine by CRE and CRE2 method was 0.803 mg/dl and 0.809 mg/dl, respectively. Bland–Altman plot shows a good agreement between the methods for serum creatinine with a mean bias of − 0.01 mg/dL for serum creatinine values ranging from 0.4 to 1.4 mg/dL. cre cre2 creatinine idms-traceable jaffe's method Medicine R Anitha Devanath verfasserin aut In Indian Journal of Health Sciences and Biomedical Research KLEU Wolters Kluwer Medknow Publications, 2019 13(2020), 2, Seite 137-139 (DE-627)1683676793 25426222 nnns volume:13 year:2020 number:2 pages:137-139 https://doi.org/10.4103/kleuhsj.kleuhsj_39_20 kostenfrei https://doaj.org/article/f2ee2275202b4fa699d5df8c38d4c2e6 kostenfrei http://www.ijournalhs.org/article.asp?issn=2542-6214;year=2020;volume=13;issue=2;spage=137;epage=139;aulast=Shanthaveeranna kostenfrei https://doaj.org/toc/2542-6214 Journal toc kostenfrei https://doaj.org/toc/2542-6222 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2020 2 137-139 |
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10.4103/kleuhsj.kleuhsj_39_20 doi (DE-627)DOAJ048280283 (DE-599)DOAJf2ee2275202b4fa699d5df8c38d4c2e6 DE-627 ger DE-627 rakwb eng Girish Konasagara Shanthaveeranna verfasserin aut Jaffe's kinetic method comparison between isotope dilution mass spectrometry standardized versus nonstandardized method 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier INTRODUCTION: Serum creatinine is estimated by several methods in different laboratories, having varying degrees of bias and imprecision, leading to different values across the laboratories with the same sample. To reduce the interlaboratory variations in creatinine assay, creatinine standardization program was established by the National Kidney Disease Education Program Laboratory Working Group and recommended that creatinine calibration should be done with material traceable to an Isotope dilution mass spectrometry (IDMS) reference measurement procedure. AIMS AND OBJECTIVE: To compare the serum creatinine estimated by CRE (calibration nonstandardized IDMS with correction factor) and CRE2 (standardized to IDMS) method. MATERIALS AND METHODS: The study was conducted in a tertiary care hospital as a part of validation of CRE2 method. Two hundred samples were selected from individuals aged between 18 and 60 years with normal serum urea, creatinine, and electrolytes based on the CRE2 method. Further, the sample is estimated for serum creatinine by CRE method on the same instrument with a correction factor (Siemens Dimension RXL with LM). Descriptive statistics and Bland–Altman analysis were used to describe the population and check for agreement between the methods. RESULTS AND CONCLUSION: The average serum creatinine by CRE and CRE2 method was 0.803 mg/dl and 0.809 mg/dl, respectively. Bland–Altman plot shows a good agreement between the methods for serum creatinine with a mean bias of − 0.01 mg/dL for serum creatinine values ranging from 0.4 to 1.4 mg/dL. cre cre2 creatinine idms-traceable jaffe's method Medicine R Anitha Devanath verfasserin aut In Indian Journal of Health Sciences and Biomedical Research KLEU Wolters Kluwer Medknow Publications, 2019 13(2020), 2, Seite 137-139 (DE-627)1683676793 25426222 nnns volume:13 year:2020 number:2 pages:137-139 https://doi.org/10.4103/kleuhsj.kleuhsj_39_20 kostenfrei https://doaj.org/article/f2ee2275202b4fa699d5df8c38d4c2e6 kostenfrei http://www.ijournalhs.org/article.asp?issn=2542-6214;year=2020;volume=13;issue=2;spage=137;epage=139;aulast=Shanthaveeranna kostenfrei https://doaj.org/toc/2542-6214 Journal toc kostenfrei https://doaj.org/toc/2542-6222 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2020 2 137-139 |
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10.4103/kleuhsj.kleuhsj_39_20 doi (DE-627)DOAJ048280283 (DE-599)DOAJf2ee2275202b4fa699d5df8c38d4c2e6 DE-627 ger DE-627 rakwb eng Girish Konasagara Shanthaveeranna verfasserin aut Jaffe's kinetic method comparison between isotope dilution mass spectrometry standardized versus nonstandardized method 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier INTRODUCTION: Serum creatinine is estimated by several methods in different laboratories, having varying degrees of bias and imprecision, leading to different values across the laboratories with the same sample. To reduce the interlaboratory variations in creatinine assay, creatinine standardization program was established by the National Kidney Disease Education Program Laboratory Working Group and recommended that creatinine calibration should be done with material traceable to an Isotope dilution mass spectrometry (IDMS) reference measurement procedure. AIMS AND OBJECTIVE: To compare the serum creatinine estimated by CRE (calibration nonstandardized IDMS with correction factor) and CRE2 (standardized to IDMS) method. MATERIALS AND METHODS: The study was conducted in a tertiary care hospital as a part of validation of CRE2 method. Two hundred samples were selected from individuals aged between 18 and 60 years with normal serum urea, creatinine, and electrolytes based on the CRE2 method. Further, the sample is estimated for serum creatinine by CRE method on the same instrument with a correction factor (Siemens Dimension RXL with LM). Descriptive statistics and Bland–Altman analysis were used to describe the population and check for agreement between the methods. RESULTS AND CONCLUSION: The average serum creatinine by CRE and CRE2 method was 0.803 mg/dl and 0.809 mg/dl, respectively. Bland–Altman plot shows a good agreement between the methods for serum creatinine with a mean bias of − 0.01 mg/dL for serum creatinine values ranging from 0.4 to 1.4 mg/dL. cre cre2 creatinine idms-traceable jaffe's method Medicine R Anitha Devanath verfasserin aut In Indian Journal of Health Sciences and Biomedical Research KLEU Wolters Kluwer Medknow Publications, 2019 13(2020), 2, Seite 137-139 (DE-627)1683676793 25426222 nnns volume:13 year:2020 number:2 pages:137-139 https://doi.org/10.4103/kleuhsj.kleuhsj_39_20 kostenfrei https://doaj.org/article/f2ee2275202b4fa699d5df8c38d4c2e6 kostenfrei http://www.ijournalhs.org/article.asp?issn=2542-6214;year=2020;volume=13;issue=2;spage=137;epage=139;aulast=Shanthaveeranna kostenfrei https://doaj.org/toc/2542-6214 Journal toc kostenfrei https://doaj.org/toc/2542-6222 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2020 2 137-139 |
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10.4103/kleuhsj.kleuhsj_39_20 doi (DE-627)DOAJ048280283 (DE-599)DOAJf2ee2275202b4fa699d5df8c38d4c2e6 DE-627 ger DE-627 rakwb eng Girish Konasagara Shanthaveeranna verfasserin aut Jaffe's kinetic method comparison between isotope dilution mass spectrometry standardized versus nonstandardized method 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier INTRODUCTION: Serum creatinine is estimated by several methods in different laboratories, having varying degrees of bias and imprecision, leading to different values across the laboratories with the same sample. To reduce the interlaboratory variations in creatinine assay, creatinine standardization program was established by the National Kidney Disease Education Program Laboratory Working Group and recommended that creatinine calibration should be done with material traceable to an Isotope dilution mass spectrometry (IDMS) reference measurement procedure. AIMS AND OBJECTIVE: To compare the serum creatinine estimated by CRE (calibration nonstandardized IDMS with correction factor) and CRE2 (standardized to IDMS) method. MATERIALS AND METHODS: The study was conducted in a tertiary care hospital as a part of validation of CRE2 method. Two hundred samples were selected from individuals aged between 18 and 60 years with normal serum urea, creatinine, and electrolytes based on the CRE2 method. Further, the sample is estimated for serum creatinine by CRE method on the same instrument with a correction factor (Siemens Dimension RXL with LM). Descriptive statistics and Bland–Altman analysis were used to describe the population and check for agreement between the methods. RESULTS AND CONCLUSION: The average serum creatinine by CRE and CRE2 method was 0.803 mg/dl and 0.809 mg/dl, respectively. Bland–Altman plot shows a good agreement between the methods for serum creatinine with a mean bias of − 0.01 mg/dL for serum creatinine values ranging from 0.4 to 1.4 mg/dL. cre cre2 creatinine idms-traceable jaffe's method Medicine R Anitha Devanath verfasserin aut In Indian Journal of Health Sciences and Biomedical Research KLEU Wolters Kluwer Medknow Publications, 2019 13(2020), 2, Seite 137-139 (DE-627)1683676793 25426222 nnns volume:13 year:2020 number:2 pages:137-139 https://doi.org/10.4103/kleuhsj.kleuhsj_39_20 kostenfrei https://doaj.org/article/f2ee2275202b4fa699d5df8c38d4c2e6 kostenfrei http://www.ijournalhs.org/article.asp?issn=2542-6214;year=2020;volume=13;issue=2;spage=137;epage=139;aulast=Shanthaveeranna kostenfrei https://doaj.org/toc/2542-6214 Journal toc kostenfrei https://doaj.org/toc/2542-6222 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2020 2 137-139 |
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10.4103/kleuhsj.kleuhsj_39_20 doi (DE-627)DOAJ048280283 (DE-599)DOAJf2ee2275202b4fa699d5df8c38d4c2e6 DE-627 ger DE-627 rakwb eng Girish Konasagara Shanthaveeranna verfasserin aut Jaffe's kinetic method comparison between isotope dilution mass spectrometry standardized versus nonstandardized method 2020 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier INTRODUCTION: Serum creatinine is estimated by several methods in different laboratories, having varying degrees of bias and imprecision, leading to different values across the laboratories with the same sample. To reduce the interlaboratory variations in creatinine assay, creatinine standardization program was established by the National Kidney Disease Education Program Laboratory Working Group and recommended that creatinine calibration should be done with material traceable to an Isotope dilution mass spectrometry (IDMS) reference measurement procedure. AIMS AND OBJECTIVE: To compare the serum creatinine estimated by CRE (calibration nonstandardized IDMS with correction factor) and CRE2 (standardized to IDMS) method. MATERIALS AND METHODS: The study was conducted in a tertiary care hospital as a part of validation of CRE2 method. Two hundred samples were selected from individuals aged between 18 and 60 years with normal serum urea, creatinine, and electrolytes based on the CRE2 method. Further, the sample is estimated for serum creatinine by CRE method on the same instrument with a correction factor (Siemens Dimension RXL with LM). Descriptive statistics and Bland–Altman analysis were used to describe the population and check for agreement between the methods. RESULTS AND CONCLUSION: The average serum creatinine by CRE and CRE2 method was 0.803 mg/dl and 0.809 mg/dl, respectively. Bland–Altman plot shows a good agreement between the methods for serum creatinine with a mean bias of − 0.01 mg/dL for serum creatinine values ranging from 0.4 to 1.4 mg/dL. cre cre2 creatinine idms-traceable jaffe's method Medicine R Anitha Devanath verfasserin aut In Indian Journal of Health Sciences and Biomedical Research KLEU Wolters Kluwer Medknow Publications, 2019 13(2020), 2, Seite 137-139 (DE-627)1683676793 25426222 nnns volume:13 year:2020 number:2 pages:137-139 https://doi.org/10.4103/kleuhsj.kleuhsj_39_20 kostenfrei https://doaj.org/article/f2ee2275202b4fa699d5df8c38d4c2e6 kostenfrei http://www.ijournalhs.org/article.asp?issn=2542-6214;year=2020;volume=13;issue=2;spage=137;epage=139;aulast=Shanthaveeranna kostenfrei https://doaj.org/toc/2542-6214 Journal toc kostenfrei https://doaj.org/toc/2542-6222 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2020 2 137-139 |
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Jaffe's kinetic method comparison between isotope dilution mass spectrometry standardized versus nonstandardized method |
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INTRODUCTION: Serum creatinine is estimated by several methods in different laboratories, having varying degrees of bias and imprecision, leading to different values across the laboratories with the same sample. To reduce the interlaboratory variations in creatinine assay, creatinine standardization program was established by the National Kidney Disease Education Program Laboratory Working Group and recommended that creatinine calibration should be done with material traceable to an Isotope dilution mass spectrometry (IDMS) reference measurement procedure. AIMS AND OBJECTIVE: To compare the serum creatinine estimated by CRE (calibration nonstandardized IDMS with correction factor) and CRE2 (standardized to IDMS) method. MATERIALS AND METHODS: The study was conducted in a tertiary care hospital as a part of validation of CRE2 method. Two hundred samples were selected from individuals aged between 18 and 60 years with normal serum urea, creatinine, and electrolytes based on the CRE2 method. Further, the sample is estimated for serum creatinine by CRE method on the same instrument with a correction factor (Siemens Dimension RXL with LM). Descriptive statistics and Bland–Altman analysis were used to describe the population and check for agreement between the methods. RESULTS AND CONCLUSION: The average serum creatinine by CRE and CRE2 method was 0.803 mg/dl and 0.809 mg/dl, respectively. Bland–Altman plot shows a good agreement between the methods for serum creatinine with a mean bias of − 0.01 mg/dL for serum creatinine values ranging from 0.4 to 1.4 mg/dL. |
abstractGer |
INTRODUCTION: Serum creatinine is estimated by several methods in different laboratories, having varying degrees of bias and imprecision, leading to different values across the laboratories with the same sample. To reduce the interlaboratory variations in creatinine assay, creatinine standardization program was established by the National Kidney Disease Education Program Laboratory Working Group and recommended that creatinine calibration should be done with material traceable to an Isotope dilution mass spectrometry (IDMS) reference measurement procedure. AIMS AND OBJECTIVE: To compare the serum creatinine estimated by CRE (calibration nonstandardized IDMS with correction factor) and CRE2 (standardized to IDMS) method. MATERIALS AND METHODS: The study was conducted in a tertiary care hospital as a part of validation of CRE2 method. Two hundred samples were selected from individuals aged between 18 and 60 years with normal serum urea, creatinine, and electrolytes based on the CRE2 method. Further, the sample is estimated for serum creatinine by CRE method on the same instrument with a correction factor (Siemens Dimension RXL with LM). Descriptive statistics and Bland–Altman analysis were used to describe the population and check for agreement between the methods. RESULTS AND CONCLUSION: The average serum creatinine by CRE and CRE2 method was 0.803 mg/dl and 0.809 mg/dl, respectively. Bland–Altman plot shows a good agreement between the methods for serum creatinine with a mean bias of − 0.01 mg/dL for serum creatinine values ranging from 0.4 to 1.4 mg/dL. |
abstract_unstemmed |
INTRODUCTION: Serum creatinine is estimated by several methods in different laboratories, having varying degrees of bias and imprecision, leading to different values across the laboratories with the same sample. To reduce the interlaboratory variations in creatinine assay, creatinine standardization program was established by the National Kidney Disease Education Program Laboratory Working Group and recommended that creatinine calibration should be done with material traceable to an Isotope dilution mass spectrometry (IDMS) reference measurement procedure. AIMS AND OBJECTIVE: To compare the serum creatinine estimated by CRE (calibration nonstandardized IDMS with correction factor) and CRE2 (standardized to IDMS) method. MATERIALS AND METHODS: The study was conducted in a tertiary care hospital as a part of validation of CRE2 method. Two hundred samples were selected from individuals aged between 18 and 60 years with normal serum urea, creatinine, and electrolytes based on the CRE2 method. Further, the sample is estimated for serum creatinine by CRE method on the same instrument with a correction factor (Siemens Dimension RXL with LM). Descriptive statistics and Bland–Altman analysis were used to describe the population and check for agreement between the methods. RESULTS AND CONCLUSION: The average serum creatinine by CRE and CRE2 method was 0.803 mg/dl and 0.809 mg/dl, respectively. Bland–Altman plot shows a good agreement between the methods for serum creatinine with a mean bias of − 0.01 mg/dL for serum creatinine values ranging from 0.4 to 1.4 mg/dL. |
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Jaffe's kinetic method comparison between isotope dilution mass spectrometry standardized versus nonstandardized method |
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