Meconium Peritonitis In Utero—the Value of Prenatal Diagnosis in Determining Neonatal Outcome

Objective: Meconium peritonitis (MP) is a chemical peritonitis caused by fetal intestinal perforation in utero. Its incidence is rare, but serious neonatal morbidity or even mortality can occur if the diagnosis is not made until after birth. Prenatal diagnosis is important in prompting early postnat...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Chao-Nin Wang [verfasserIn] Shuenn-Dyh Chang [verfasserIn] An-Shine Chao [verfasserIn] Tzu-Hao Wang [verfasserIn] Ling-Hong Tseng [verfasserIn] Yao-Lung Chang [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2008

Schlagwörter:	calcification fetal ascites meconium peritonitis prenatal ultrasound pseudocyst

Übergeordnetes Werk:	In: Taiwanese Journal of Obstetrics & Gynecology - Elsevier, 2017, 47(2008), 4, Seite 391-396
Übergeordnetes Werk:	volume:47 ; year:2008 ; number:4 ; pages:391-396

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1016/S1028-4559(09)60004-8

Katalog-ID:	DOAJ048646679

Internformat


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520			\|a Objective: Meconium peritonitis (MP) is a chemical peritonitis caused by fetal intestinal perforation in utero. Its incidence is rare, but serious neonatal morbidity or even mortality can occur if the diagnosis is not made until after birth. Prenatal diagnosis is important in prompting early postnatal surgical intervention, and so improving neonatal outcome. Materials and Methods: Fourteen cases diagnosed in utero with MP from January 1996 to December 2005 were enrolled in this study. The final diagnoses were established by surgical findings or postnatal radiography. The prenatal ultrasound features, neonatal birth characteristics, surgical findings, postnatal management and neonatal outcomes were reviewed. Results: All infants received follow-up care at our hospital. Prenatal ultrasound findings included fetal ascites (100%), intra-abdominal calcification (93%), dilated bowel loops (57%), pseudocysts (29%), and polyhydramnios (50%). Four infants (4/14; 28.5%) did not undergo postnatal surgery, but survived well. The mean gestational age at detection was significantly earlier in the non-surgery group (23 ± 3.6 weeks) than in the surgery group (31.7 ± 2.5 weeks). One infant (7.1%) died because of sepsis after two neonatal operations. The overall survival rate was 92.9%. Conclusion: MP can be diagnosed by prenatal ultrasound, and the neonatal outcome is favorable. Early detection is not associated with poor neonatal outcome, and selective termination is unnecessary. Resolution of dilated bowel loops and polyhydramnios predict a low rate of postnatal surgical intervention.
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allfields	10.1016/S1028-4559(09)60004-8 doi (DE-627)DOAJ048646679 (DE-599)DOAJc2c520cacd834f839c59b3a6963cd308 DE-627 ger DE-627 rakwb eng RG1-991 Chao-Nin Wang verfasserin aut Meconium Peritonitis In Utero—the Value of Prenatal Diagnosis in Determining Neonatal Outcome 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: Meconium peritonitis (MP) is a chemical peritonitis caused by fetal intestinal perforation in utero. Its incidence is rare, but serious neonatal morbidity or even mortality can occur if the diagnosis is not made until after birth. Prenatal diagnosis is important in prompting early postnatal surgical intervention, and so improving neonatal outcome. Materials and Methods: Fourteen cases diagnosed in utero with MP from January 1996 to December 2005 were enrolled in this study. The final diagnoses were established by surgical findings or postnatal radiography. The prenatal ultrasound features, neonatal birth characteristics, surgical findings, postnatal management and neonatal outcomes were reviewed. Results: All infants received follow-up care at our hospital. Prenatal ultrasound findings included fetal ascites (100%), intra-abdominal calcification (93%), dilated bowel loops (57%), pseudocysts (29%), and polyhydramnios (50%). Four infants (4/14; 28.5%) did not undergo postnatal surgery, but survived well. The mean gestational age at detection was significantly earlier in the non-surgery group (23 ± 3.6 weeks) than in the surgery group (31.7 ± 2.5 weeks). One infant (7.1%) died because of sepsis after two neonatal operations. The overall survival rate was 92.9%. Conclusion: MP can be diagnosed by prenatal ultrasound, and the neonatal outcome is favorable. Early detection is not associated with poor neonatal outcome, and selective termination is unnecessary. Resolution of dilated bowel loops and polyhydramnios predict a low rate of postnatal surgical intervention. calcification fetal ascites meconium peritonitis prenatal ultrasound pseudocyst Gynecology and obstetrics Shuenn-Dyh Chang verfasserin aut An-Shine Chao verfasserin aut Tzu-Hao Wang verfasserin aut Ling-Hong Tseng verfasserin aut Yao-Lung Chang verfasserin aut In Taiwanese Journal of Obstetrics & Gynecology Elsevier, 2017 47(2008), 4, Seite 391-396 (DE-627)500021422 (DE-600)2202946-1 10284559 nnns volume:47 year:2008 number:4 pages:391-396 https://doi.org/10.1016/S1028-4559(09)60004-8 kostenfrei https://doaj.org/article/c2c520cacd834f839c59b3a6963cd308 kostenfrei http://www.sciencedirect.com/science/article/pii/S1028455909600048 kostenfrei https://doaj.org/toc/1028-4559 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_647 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 47 2008 4 391-396
spelling	10.1016/S1028-4559(09)60004-8 doi (DE-627)DOAJ048646679 (DE-599)DOAJc2c520cacd834f839c59b3a6963cd308 DE-627 ger DE-627 rakwb eng RG1-991 Chao-Nin Wang verfasserin aut Meconium Peritonitis In Utero—the Value of Prenatal Diagnosis in Determining Neonatal Outcome 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: Meconium peritonitis (MP) is a chemical peritonitis caused by fetal intestinal perforation in utero. Its incidence is rare, but serious neonatal morbidity or even mortality can occur if the diagnosis is not made until after birth. Prenatal diagnosis is important in prompting early postnatal surgical intervention, and so improving neonatal outcome. Materials and Methods: Fourteen cases diagnosed in utero with MP from January 1996 to December 2005 were enrolled in this study. The final diagnoses were established by surgical findings or postnatal radiography. The prenatal ultrasound features, neonatal birth characteristics, surgical findings, postnatal management and neonatal outcomes were reviewed. Results: All infants received follow-up care at our hospital. Prenatal ultrasound findings included fetal ascites (100%), intra-abdominal calcification (93%), dilated bowel loops (57%), pseudocysts (29%), and polyhydramnios (50%). Four infants (4/14; 28.5%) did not undergo postnatal surgery, but survived well. The mean gestational age at detection was significantly earlier in the non-surgery group (23 ± 3.6 weeks) than in the surgery group (31.7 ± 2.5 weeks). One infant (7.1%) died because of sepsis after two neonatal operations. The overall survival rate was 92.9%. Conclusion: MP can be diagnosed by prenatal ultrasound, and the neonatal outcome is favorable. Early detection is not associated with poor neonatal outcome, and selective termination is unnecessary. Resolution of dilated bowel loops and polyhydramnios predict a low rate of postnatal surgical intervention. calcification fetal ascites meconium peritonitis prenatal ultrasound pseudocyst Gynecology and obstetrics Shuenn-Dyh Chang verfasserin aut An-Shine Chao verfasserin aut Tzu-Hao Wang verfasserin aut Ling-Hong Tseng verfasserin aut Yao-Lung Chang verfasserin aut In Taiwanese Journal of Obstetrics & Gynecology Elsevier, 2017 47(2008), 4, Seite 391-396 (DE-627)500021422 (DE-600)2202946-1 10284559 nnns volume:47 year:2008 number:4 pages:391-396 https://doi.org/10.1016/S1028-4559(09)60004-8 kostenfrei https://doaj.org/article/c2c520cacd834f839c59b3a6963cd308 kostenfrei http://www.sciencedirect.com/science/article/pii/S1028455909600048 kostenfrei https://doaj.org/toc/1028-4559 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_647 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 47 2008 4 391-396
allfields_unstemmed	10.1016/S1028-4559(09)60004-8 doi (DE-627)DOAJ048646679 (DE-599)DOAJc2c520cacd834f839c59b3a6963cd308 DE-627 ger DE-627 rakwb eng RG1-991 Chao-Nin Wang verfasserin aut Meconium Peritonitis In Utero—the Value of Prenatal Diagnosis in Determining Neonatal Outcome 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: Meconium peritonitis (MP) is a chemical peritonitis caused by fetal intestinal perforation in utero. Its incidence is rare, but serious neonatal morbidity or even mortality can occur if the diagnosis is not made until after birth. Prenatal diagnosis is important in prompting early postnatal surgical intervention, and so improving neonatal outcome. Materials and Methods: Fourteen cases diagnosed in utero with MP from January 1996 to December 2005 were enrolled in this study. The final diagnoses were established by surgical findings or postnatal radiography. The prenatal ultrasound features, neonatal birth characteristics, surgical findings, postnatal management and neonatal outcomes were reviewed. Results: All infants received follow-up care at our hospital. Prenatal ultrasound findings included fetal ascites (100%), intra-abdominal calcification (93%), dilated bowel loops (57%), pseudocysts (29%), and polyhydramnios (50%). Four infants (4/14; 28.5%) did not undergo postnatal surgery, but survived well. The mean gestational age at detection was significantly earlier in the non-surgery group (23 ± 3.6 weeks) than in the surgery group (31.7 ± 2.5 weeks). One infant (7.1%) died because of sepsis after two neonatal operations. The overall survival rate was 92.9%. Conclusion: MP can be diagnosed by prenatal ultrasound, and the neonatal outcome is favorable. Early detection is not associated with poor neonatal outcome, and selective termination is unnecessary. Resolution of dilated bowel loops and polyhydramnios predict a low rate of postnatal surgical intervention. calcification fetal ascites meconium peritonitis prenatal ultrasound pseudocyst Gynecology and obstetrics Shuenn-Dyh Chang verfasserin aut An-Shine Chao verfasserin aut Tzu-Hao Wang verfasserin aut Ling-Hong Tseng verfasserin aut Yao-Lung Chang verfasserin aut In Taiwanese Journal of Obstetrics & Gynecology Elsevier, 2017 47(2008), 4, Seite 391-396 (DE-627)500021422 (DE-600)2202946-1 10284559 nnns volume:47 year:2008 number:4 pages:391-396 https://doi.org/10.1016/S1028-4559(09)60004-8 kostenfrei https://doaj.org/article/c2c520cacd834f839c59b3a6963cd308 kostenfrei http://www.sciencedirect.com/science/article/pii/S1028455909600048 kostenfrei https://doaj.org/toc/1028-4559 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_647 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 47 2008 4 391-396
allfieldsGer	10.1016/S1028-4559(09)60004-8 doi (DE-627)DOAJ048646679 (DE-599)DOAJc2c520cacd834f839c59b3a6963cd308 DE-627 ger DE-627 rakwb eng RG1-991 Chao-Nin Wang verfasserin aut Meconium Peritonitis In Utero—the Value of Prenatal Diagnosis in Determining Neonatal Outcome 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: Meconium peritonitis (MP) is a chemical peritonitis caused by fetal intestinal perforation in utero. Its incidence is rare, but serious neonatal morbidity or even mortality can occur if the diagnosis is not made until after birth. Prenatal diagnosis is important in prompting early postnatal surgical intervention, and so improving neonatal outcome. Materials and Methods: Fourteen cases diagnosed in utero with MP from January 1996 to December 2005 were enrolled in this study. The final diagnoses were established by surgical findings or postnatal radiography. The prenatal ultrasound features, neonatal birth characteristics, surgical findings, postnatal management and neonatal outcomes were reviewed. Results: All infants received follow-up care at our hospital. Prenatal ultrasound findings included fetal ascites (100%), intra-abdominal calcification (93%), dilated bowel loops (57%), pseudocysts (29%), and polyhydramnios (50%). Four infants (4/14; 28.5%) did not undergo postnatal surgery, but survived well. The mean gestational age at detection was significantly earlier in the non-surgery group (23 ± 3.6 weeks) than in the surgery group (31.7 ± 2.5 weeks). One infant (7.1%) died because of sepsis after two neonatal operations. The overall survival rate was 92.9%. Conclusion: MP can be diagnosed by prenatal ultrasound, and the neonatal outcome is favorable. Early detection is not associated with poor neonatal outcome, and selective termination is unnecessary. Resolution of dilated bowel loops and polyhydramnios predict a low rate of postnatal surgical intervention. calcification fetal ascites meconium peritonitis prenatal ultrasound pseudocyst Gynecology and obstetrics Shuenn-Dyh Chang verfasserin aut An-Shine Chao verfasserin aut Tzu-Hao Wang verfasserin aut Ling-Hong Tseng verfasserin aut Yao-Lung Chang verfasserin aut In Taiwanese Journal of Obstetrics & Gynecology Elsevier, 2017 47(2008), 4, Seite 391-396 (DE-627)500021422 (DE-600)2202946-1 10284559 nnns volume:47 year:2008 number:4 pages:391-396 https://doi.org/10.1016/S1028-4559(09)60004-8 kostenfrei https://doaj.org/article/c2c520cacd834f839c59b3a6963cd308 kostenfrei http://www.sciencedirect.com/science/article/pii/S1028455909600048 kostenfrei https://doaj.org/toc/1028-4559 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_647 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 47 2008 4 391-396
allfieldsSound	10.1016/S1028-4559(09)60004-8 doi (DE-627)DOAJ048646679 (DE-599)DOAJc2c520cacd834f839c59b3a6963cd308 DE-627 ger DE-627 rakwb eng RG1-991 Chao-Nin Wang verfasserin aut Meconium Peritonitis In Utero—the Value of Prenatal Diagnosis in Determining Neonatal Outcome 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective: Meconium peritonitis (MP) is a chemical peritonitis caused by fetal intestinal perforation in utero. Its incidence is rare, but serious neonatal morbidity or even mortality can occur if the diagnosis is not made until after birth. Prenatal diagnosis is important in prompting early postnatal surgical intervention, and so improving neonatal outcome. Materials and Methods: Fourteen cases diagnosed in utero with MP from January 1996 to December 2005 were enrolled in this study. The final diagnoses were established by surgical findings or postnatal radiography. The prenatal ultrasound features, neonatal birth characteristics, surgical findings, postnatal management and neonatal outcomes were reviewed. Results: All infants received follow-up care at our hospital. Prenatal ultrasound findings included fetal ascites (100%), intra-abdominal calcification (93%), dilated bowel loops (57%), pseudocysts (29%), and polyhydramnios (50%). Four infants (4/14; 28.5%) did not undergo postnatal surgery, but survived well. The mean gestational age at detection was significantly earlier in the non-surgery group (23 ± 3.6 weeks) than in the surgery group (31.7 ± 2.5 weeks). One infant (7.1%) died because of sepsis after two neonatal operations. The overall survival rate was 92.9%. Conclusion: MP can be diagnosed by prenatal ultrasound, and the neonatal outcome is favorable. Early detection is not associated with poor neonatal outcome, and selective termination is unnecessary. Resolution of dilated bowel loops and polyhydramnios predict a low rate of postnatal surgical intervention. calcification fetal ascites meconium peritonitis prenatal ultrasound pseudocyst Gynecology and obstetrics Shuenn-Dyh Chang verfasserin aut An-Shine Chao verfasserin aut Tzu-Hao Wang verfasserin aut Ling-Hong Tseng verfasserin aut Yao-Lung Chang verfasserin aut In Taiwanese Journal of Obstetrics & Gynecology Elsevier, 2017 47(2008), 4, Seite 391-396 (DE-627)500021422 (DE-600)2202946-1 10284559 nnns volume:47 year:2008 number:4 pages:391-396 https://doi.org/10.1016/S1028-4559(09)60004-8 kostenfrei https://doaj.org/article/c2c520cacd834f839c59b3a6963cd308 kostenfrei http://www.sciencedirect.com/science/article/pii/S1028455909600048 kostenfrei https://doaj.org/toc/1028-4559 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_647 GBV_ILN_2014 GBV_ILN_2068 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 47 2008 4 391-396
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source	In Taiwanese Journal of Obstetrics & Gynecology 47(2008), 4, Seite 391-396 volume:47 year:2008 number:4 pages:391-396
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Its incidence is rare, but serious neonatal morbidity or even mortality can occur if the diagnosis is not made until after birth. Prenatal diagnosis is important in prompting early postnatal surgical intervention, and so improving neonatal outcome. Materials and Methods: Fourteen cases diagnosed in utero with MP from January 1996 to December 2005 were enrolled in this study. The final diagnoses were established by surgical findings or postnatal radiography. The prenatal ultrasound features, neonatal birth characteristics, surgical findings, postnatal management and neonatal outcomes were reviewed. Results: All infants received follow-up care at our hospital. Prenatal ultrasound findings included fetal ascites (100%), intra-abdominal calcification (93%), dilated bowel loops (57%), pseudocysts (29%), and polyhydramnios (50%). Four infants (4/14; 28.5%) did not undergo postnatal surgery, but survived well. The mean gestational age at detection was significantly earlier in the non-surgery group (23 ± 3.6 weeks) than in the surgery group (31.7 ± 2.5 weeks). One infant (7.1%) died because of sepsis after two neonatal operations. The overall survival rate was 92.9%. Conclusion: MP can be diagnosed by prenatal ultrasound, and the neonatal outcome is favorable. Early detection is not associated with poor neonatal outcome, and selective termination is unnecessary. 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callnumber-first	R - Medicine
author	Chao-Nin Wang
spellingShingle	Chao-Nin Wang misc RG1-991 misc calcification misc fetal ascites misc meconium peritonitis misc prenatal ultrasound misc pseudocyst misc Gynecology and obstetrics Meconium Peritonitis In Utero—the Value of Prenatal Diagnosis in Determining Neonatal Outcome
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topic_title	RG1-991 Meconium Peritonitis In Utero—the Value of Prenatal Diagnosis in Determining Neonatal Outcome calcification fetal ascites meconium peritonitis prenatal ultrasound pseudocyst
topic	misc RG1-991 misc calcification misc fetal ascites misc meconium peritonitis misc prenatal ultrasound misc pseudocyst misc Gynecology and obstetrics
topic_unstemmed	misc RG1-991 misc calcification misc fetal ascites misc meconium peritonitis misc prenatal ultrasound misc pseudocyst misc Gynecology and obstetrics
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title	Meconium Peritonitis In Utero—the Value of Prenatal Diagnosis in Determining Neonatal Outcome
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title_full	Meconium Peritonitis In Utero—the Value of Prenatal Diagnosis in Determining Neonatal Outcome
author_sort	Chao-Nin Wang
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author_browse	Chao-Nin Wang Shuenn-Dyh Chang An-Shine Chao Tzu-Hao Wang Ling-Hong Tseng Yao-Lung Chang
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title_sort	meconium peritonitis in utero—the value of prenatal diagnosis in determining neonatal outcome
callnumber	RG1-991
title_auth	Meconium Peritonitis In Utero—the Value of Prenatal Diagnosis in Determining Neonatal Outcome
abstract	Objective: Meconium peritonitis (MP) is a chemical peritonitis caused by fetal intestinal perforation in utero. Its incidence is rare, but serious neonatal morbidity or even mortality can occur if the diagnosis is not made until after birth. Prenatal diagnosis is important in prompting early postnatal surgical intervention, and so improving neonatal outcome. Materials and Methods: Fourteen cases diagnosed in utero with MP from January 1996 to December 2005 were enrolled in this study. The final diagnoses were established by surgical findings or postnatal radiography. The prenatal ultrasound features, neonatal birth characteristics, surgical findings, postnatal management and neonatal outcomes were reviewed. Results: All infants received follow-up care at our hospital. Prenatal ultrasound findings included fetal ascites (100%), intra-abdominal calcification (93%), dilated bowel loops (57%), pseudocysts (29%), and polyhydramnios (50%). Four infants (4/14; 28.5%) did not undergo postnatal surgery, but survived well. The mean gestational age at detection was significantly earlier in the non-surgery group (23 ± 3.6 weeks) than in the surgery group (31.7 ± 2.5 weeks). One infant (7.1%) died because of sepsis after two neonatal operations. The overall survival rate was 92.9%. Conclusion: MP can be diagnosed by prenatal ultrasound, and the neonatal outcome is favorable. Early detection is not associated with poor neonatal outcome, and selective termination is unnecessary. Resolution of dilated bowel loops and polyhydramnios predict a low rate of postnatal surgical intervention.
abstractGer	Objective: Meconium peritonitis (MP) is a chemical peritonitis caused by fetal intestinal perforation in utero. Its incidence is rare, but serious neonatal morbidity or even mortality can occur if the diagnosis is not made until after birth. Prenatal diagnosis is important in prompting early postnatal surgical intervention, and so improving neonatal outcome. Materials and Methods: Fourteen cases diagnosed in utero with MP from January 1996 to December 2005 were enrolled in this study. The final diagnoses were established by surgical findings or postnatal radiography. The prenatal ultrasound features, neonatal birth characteristics, surgical findings, postnatal management and neonatal outcomes were reviewed. Results: All infants received follow-up care at our hospital. Prenatal ultrasound findings included fetal ascites (100%), intra-abdominal calcification (93%), dilated bowel loops (57%), pseudocysts (29%), and polyhydramnios (50%). Four infants (4/14; 28.5%) did not undergo postnatal surgery, but survived well. The mean gestational age at detection was significantly earlier in the non-surgery group (23 ± 3.6 weeks) than in the surgery group (31.7 ± 2.5 weeks). One infant (7.1%) died because of sepsis after two neonatal operations. The overall survival rate was 92.9%. Conclusion: MP can be diagnosed by prenatal ultrasound, and the neonatal outcome is favorable. Early detection is not associated with poor neonatal outcome, and selective termination is unnecessary. Resolution of dilated bowel loops and polyhydramnios predict a low rate of postnatal surgical intervention.
abstract_unstemmed	Objective: Meconium peritonitis (MP) is a chemical peritonitis caused by fetal intestinal perforation in utero. Its incidence is rare, but serious neonatal morbidity or even mortality can occur if the diagnosis is not made until after birth. Prenatal diagnosis is important in prompting early postnatal surgical intervention, and so improving neonatal outcome. Materials and Methods: Fourteen cases diagnosed in utero with MP from January 1996 to December 2005 were enrolled in this study. The final diagnoses were established by surgical findings or postnatal radiography. The prenatal ultrasound features, neonatal birth characteristics, surgical findings, postnatal management and neonatal outcomes were reviewed. Results: All infants received follow-up care at our hospital. Prenatal ultrasound findings included fetal ascites (100%), intra-abdominal calcification (93%), dilated bowel loops (57%), pseudocysts (29%), and polyhydramnios (50%). Four infants (4/14; 28.5%) did not undergo postnatal surgery, but survived well. The mean gestational age at detection was significantly earlier in the non-surgery group (23 ± 3.6 weeks) than in the surgery group (31.7 ± 2.5 weeks). One infant (7.1%) died because of sepsis after two neonatal operations. The overall survival rate was 92.9%. Conclusion: MP can be diagnosed by prenatal ultrasound, and the neonatal outcome is favorable. Early detection is not associated with poor neonatal outcome, and selective termination is unnecessary. Resolution of dilated bowel loops and polyhydramnios predict a low rate of postnatal surgical intervention.
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title_short	Meconium Peritonitis In Utero—the Value of Prenatal Diagnosis in Determining Neonatal Outcome
url	https://doi.org/10.1016/S1028-4559(09)60004-8 https://doaj.org/article/c2c520cacd834f839c59b3a6963cd308 http://www.sciencedirect.com/science/article/pii/S1028455909600048 https://doaj.org/toc/1028-4559
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up_date	2024-07-03T18:55:44.376Z
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The mean gestational age at detection was significantly earlier in the non-surgery group (23 ± 3.6 weeks) than in the surgery group (31.7 ± 2.5 weeks). One infant (7.1%) died because of sepsis after two neonatal operations. The overall survival rate was 92.9%. Conclusion: MP can be diagnosed by prenatal ultrasound, and the neonatal outcome is favorable. Early detection is not associated with poor neonatal outcome, and selective termination is unnecessary. 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